{"id":4901,"date":"2018-08-07T07:43:06","date_gmt":"2018-08-07T07:43:06","guid":{"rendered":"http:\/\/mirth0\/en\/?page_id=4901"},"modified":"2018-10-09T11:12:20","modified_gmt":"2018-10-09T11:12:20","slug":"clinical-translational-oncology","status":"publish","type":"page","link":"https:\/\/imas12.es\/en\/research\/cancer\/clinical-translational-oncology\/","title":{"rendered":"Thoracic and Clinical-Translational Oncology"},"content":{"rendered":"

The goal of the Research Group in Thoracic and Clinical-Translational Oncology<\/strong> is to characterize thoracic tumors from a molecular viewpoint and to understand the biological mechanisms governing their growth. The research group integrates clinical-translational research with the daily healthcare practice, and is committed to implement the medical advances achieved in the laboratory in standard clinical practice.<\/p>\n

Scientific objectives and lines of work<\/h2>\n
    \n
  1. Molecular characterization of thoracic neoplasms.<\/li>\n
  2. Translational development of novel biomarkers.<\/li>\n
  3. Preclinical evaluation of new therapeutic strategies using patient-derived xenograft (PDX) mouse models.<\/li>\n
  4. Early clinical trials.<\/li>\n
  5. Improvements in standard clinical practice in lung cancer.<\/li>\n<\/ol>\n

    Specific objectives<\/h2>\n
      \n
    1. Molecular characterization of thoracic neoplasms.\n
        \n
      1. Molecular taxonomy of lung cancer<\/li>\n
      2. Integral molecular and immunological profiling of non-small cell lung cancer (NSCLC). Design and validation of adapted immunotherapy approaches<\/li>\n<\/ol>\n<\/li>\n
      3. Translational development of novel biomarkers.\n
          \n
        1. Study of new biomarkers aimed at determining the efficacy of the inhibition of FGFR1\/4 as a therapeutic approach for lung cancer<\/li>\n
        2. Study of new diagnostic biomarkers of lung cancer<\/li>\n<\/ol>\n<\/li>\n
        3. Preclinical evaluation of new therapeutic strategies using PDX mouse models.<\/li>\n
        4. Early clinical trials.<\/li>\n
        5. Improvements in standard clinical practice in lung cancer.<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

          The goal of the Research Group in Thoracic and Clinical-Translational Oncology is to characterize thoracic tumors from a molecular viewpoint and to understand the biological mechanisms governing their growth. The research group integrates clinical-translational research with the daily healthcare practice,…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":24,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"research-group.php","meta":{"footnotes":""},"class_list":["post-4901","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages\/4901","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/comments?post=4901"}],"version-history":[{"count":3,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages\/4901\/revisions"}],"predecessor-version":[{"id":5075,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages\/4901\/revisions\/5075"}],"up":[{"embeddable":true,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages\/24"}],"wp:attachment":[{"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/media?parent=4901"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}