{"id":4908,"date":"2018-08-07T08:12:36","date_gmt":"2018-08-07T08:12:36","guid":{"rendered":"http:\/\/mirth0\/en\/?page_id=4908"},"modified":"2025-07-23T15:42:05","modified_gmt":"2025-07-23T15:42:05","slug":"lymphoid-differentiation","status":"publish","type":"page","link":"https:\/\/imas12.es\/en\/research\/cancer\/lymphoid-differentiation\/","title":{"rendered":"Stem Cells, Immunity and Cancer"},"content":{"rendered":"

Research interests<\/h2>\n
    \n
  1. Thymus\n
      \n
    1. Role of FoxN1 in the early thymic morphogenesis and the differentiation of medullary epithelium involved in central tolerance<\/li>\n
    2. Role of Thymocytes-Thymic epithelial cells (TECs) in the generation of T-cell repertoire\n
        \n
      1. The immune condition in mouse mutants suffering deficiences in the thymic epitelial component<\/li>\n
      2. Determination of the minimal requests needed by thymocytes and TECs for the generation of an immunocompetent T-cell repertoire<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n<\/li>\n
      3. Role of Eph and ephrins in the biology of normal and pathological MSCs\n
          \n
        1. Relevance of EphB2 vs EphB3 signalling for osteogenic differentiation of MSC<\/li>\n
        2. Role of Eph and ephrins in the cell interactions between bone marrow-derived MSC and normal and neoplasia hematopoietic stem cells: The condition in the tumoral niches of patients suffering Jak2- myeloproliferative syndromes<\/li>\n<\/ol>\n<\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"

          Research interests Thymus Role of FoxN1 in the early thymic morphogenesis and the differentiation of medullary epithelium involved in central tolerance Role of Thymocytes-Thymic epithelial cells (TECs) in the generation of T-cell repertoire The immune condition in mouse mutants suffering…<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":24,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"research-group.php","meta":{"footnotes":""},"class_list":["post-4908","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages\/4908","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/comments?post=4908"}],"version-history":[{"count":3,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages\/4908\/revisions"}],"predecessor-version":[{"id":6110,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages\/4908\/revisions\/6110"}],"up":[{"embeddable":true,"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/pages\/24"}],"wp:attachment":[{"href":"https:\/\/imas12.es\/en\/wp-json\/wp\/v2\/media?parent=4908"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}