Skip to main content Skip to search

Oncología Genitourinaria y Celular y Molecular

Publicaciones

2023

Juan, A, Segrelles, C, del Campo-Balguerías, A, Bravo, I, Silva, I, Peral, J, Ocaña, A, Clemente-Casares, P, Alonso-Moreno, C, Lorz, C (2023).

Anti-EGFR conjugated nanoparticles to deliver Alpelisib as targeted therapy for head and neck cancer

Cancer Nanotechnology. Article. 14(1).
[doi:10.1186/s12645-023-00180-z]
Rodríguez-Izquierdo, M, del Cañizo, CG, Rubio, C, Reina, IA, Arroyo, MH, Antolin, AR, Porto, MD, Guerrero-Ramos, F (2023).

Immune Predictors of Response after Bacillus Calmette-Guerin Treatment in Non-Muscle-Invasive Bladder Cancer

Cancers. Review. 15(23).
[doi:10.3390/cancers15235554]
Bedke, J, Black, PC, Szabados, B, Guerrero-Ramosd, F, Shariate, SF, Xylinas, E, Brinkmann, J, Blake-Haskins, JA, Cesari, R, Redorta, JP (2023).

Optimizing outcomes for high-risk, non-muscle-invasive bladder cancer: The evolving role of PD-(L)1 inhibition

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS. Review. 41(12):461-475.
[doi:10.1016/j.urolonc.2023.10.004]
Subiela, JD, Sellés, EG, Maldonado, A, Campos, FL, Ovide, JA, Illarramendi, OA, González-Padilla, DA, Gajate, P, Polledo, LEO, Gregorio, SAY, Guerrero-Ramos, F, Dos Santos, VG, Rodríguez-Patrón, R, Calais, J, Kishan, AU, Revilla, FJB, Couañgo, F (2023).

Clinical Usefulness of Prostate-specific Membrane Antigen-ligand Positron Emission Tomography/Computed Tomography for the Detection of Prostate Cancer Biochemical Recurrence after Primary Radiation Therapy in Patients with Prostate-specific Antigen Below the Phoenix Threshold: Systematic Review and Meta-analysis

CLINICAL ONCOLOGY. Review. 35(12):676-688.
[doi:10.1016/j.clon.2023.09.012]
Lodewijk, I, Duenas, M, Paramio, JM, Rubio, C (2023).

CD44v6, STn & O-GD2: promising tumor associated antigens paving the way for new targeted cancer therapies

Frontiers in immunology. Review. 14.
[doi:10.3389/fimmu.2023.1272681]
Recuero, E, Lázaro, S, Lorz, C, Enguita, AB, Garcia-Escudero, R, Santos, M (2023).

Novel Mouse Cell Lines and In Vivo Models for Human High-Grade Neuroendocrine Lung Carcinoma, Small Cell Lung Carcinoma (SCLC), and Large Cell Neuroendocrine Carcinoma (LCNEC)

International Journal Of Molecular Sciences. Article. 24(20).
[doi:10.3390/ijms242015284]
Alvarez, SJ, Utrera, NRM, Ojeda, JMD, Sutil, RS, Gil-Moradillo, J, Guerrero-Ramos, F, Hernández-Arroyo, M, de la Blanca, RSP, Antolín, AR, del Cañizo, CG (2023).

Extrauterine Retroperitoneal Leiomyomas: 3 Case Reports and Review of the Literature

UROLOGIA INTERNATIONALIS. Review. 107(8):814-818.
[doi:10.1159/000530213]
Nguyen, HT, Tang, WL, Webster, ALH, Whiteaker, JR, Chandler, CM, Errazquin, R, Roohollahi, K, Fritzke, M, Hoskins, EE, Jonlin, E, Wakefield, L, Sullivan, LB, Chen, EY, Dorsman, J, Brakenhoff, R, Paulovich, AG, Grompe, M, Garcia-Escudero, R, Wells, SI, Smogorzewska, A, Monnat, RJ Jr (2023).

Fanconi anemia-isogenic head and neck cancer cell line pairs: A basic and translational science resource

INTERNATIONAL JOURNAL OF CANCER. Article. 153(1):183-196.
[doi:10.1002/ijc.34506]
Tyson, MD, Morris, D, Palou, J, Rodriguez, O, Mir, MC, Dickstein, RJ, Guerrero-Ramos, F, Scarpato, KR, Hafron, JM, Messing, EM, Cutie, CJ, Maffeo, JC, Raybold, B, Chau, A, Stromberg, KA, Keegan, KA (2023).

Reply by Authors.

JOURNAL OF UROLOGY. Article. 209(5):900-900.
[doi:10.1097/JU.0000000000003195.02]
Tyson, MD, Morris, D, Palou, J, Rodriguez, O, Mir, MC, Dickstein, RJ, Guerrero-Ramos, F, Scarpato, KR, Hafron, JM, Messing, EM, Cutie, CJ, Maffeo, JC, Raybold, B, Chau, A, Stromberg, KA, Keegan, KA (2023).

Safety, Tolerability, and Preliminary Efficacy of TAR-200 in Patients With Muscle-invasive Bladder Cancer Who Refused or Were Unfit for Curative-intent Therapy: A Phase 1 Study

JOURNAL OF UROLOGY. Article. 209(5):890-900.
[doi:10.1097/JU.0000000000003195]
Ramírez-Pardo I, Villarejo-Zori B, Jiménez-Loygorri JI, Sierra-Filardi E, Alonso-Gil S, Mariño G, de la Villa P, Fitze PS, Fuentes JM, García-Escudero R, Ferrington DA, Gomez-Sintes R, Boya P (2023).

Ambra1 haploinsufficiency in CD1 mice results in metabolic alterations and exacerbates age-associated retinal degeneration.

Autophagy. Article. 19(3):1-21.
[doi:10.1080/15548627.2022.2103307]
Fernández-Cortés, M, Delgado-Bellido, D, Bermúdez-Jiménez, E, Paramio, JM, O'Valle, F, Vinckier, S, Carmeliet, P, Garcia-Diaz, A, Oliver, FJ (2023).

PARP inhibition promotes endothelial-like traits in melanoma cells and modulates pericyte coverage dynamics during vasculogenic mimicry

JOURNAL OF PATHOLOGY. Article. 259(3):318-330.
[doi:10.1002/path.6043]
Errazquin, R, Carrasco, E, Del Marro, S, Suñol, A, Peral, J, Ortiz, J, Rubio, JC, Segrelles, C, Dueñas, M, Garrido-Aranda, A, Alvarez, M, Belendez, C, Balmaña, J, Garcia-Escudero, R (2023).

Early Diagnosis of Oral Cancer and Lesions in Fanconi Anemia Patients: A Prospective and Longitudinal Study Using Saliva and Plasma

Cancers. Article. 15(6).
[doi:10.3390/cancers15061871]
Borque-Fernando, A, Gaya, JM, Esteban-Escaño, LM, Gómez-Rivas, J, García-Baquero, R, Agreda-Castañeda, F, Gallioli, A, Verri, P, Ortiz-Vico, FJ, Amir-Nicolau, BF, Osman-Garcia, I, Gil-Martínez, P, Arrabal-Martín, M, Lozano, AGF, Campos-Juanatey, F, Guerrero-Ramos, F, Rubio-Briones, J (2023).

Epidemiology, Diagnosis and Management of Penile Cancer: Results from the Spanish National Registry of Penile Cancer

Cancers. Article. 15(3).
[doi:10.3390/cancers15030616]
Hervás-Salcedo, R, Fernández-García, M, Hernando-Rodríguez, M, Suárez-Cabrera, C, Bueren, JA, Yáñez, RM (2023).

Improved efficacy of mesenchymal stromal cells stably expressing CXCR4 and IL-10 in a xenogeneic graft versus host disease mouse model

Frontiers in immunology. Article. 14.
[doi:10.3389/fimmu.2023.1062086]
Soengas-Gonda, E, de la Fuente, RP, Arteche-Lopez, A, Gomez-Cano, MD, Quesada-Espinosa, JF, Milla, CP, Rosales, JML, de Andres, SM, Sanchez-Calvin, MT, Gomez-Rodriguez, MJ, Tomillo, OS, Rufian, AJ, Gomez, PR, Herrero-Forte, C, Fenollar-Cortes, M, Cotarelo-Perez, C, Ron, AG, Rodriguez, OP, Oancea-Ionescu, R, Moreno-Garcia, M (2023).

Expanding the Phenotypic Spectrum of Alazami Syndrome: Two Unrelated Spanish Families

Neuropediatrics. Article. 54(01):31-36.
[doi:10.1055/a-1947-8411]
Santos, M, Lanillos, J, Caleiras, E, Valdivia, C, Roldan-Romero, JM, Lainez, N, Puente, J, Beuselinck, B, Oudard, S, Zucman-Rossi, J, Navarro, P, Robledo, M, Castellano, D, de Velasco, G, Garcia-Donas, J, Rodriguez-Antona, C (2023).

PBRM1 and KDM5C cooperate to define high-angiogenesis tumors and increased antiangiogenic response in renal cancer

AMERICAN JOURNAL OF CANCER RESEARCH. Article. 13(5):2116-2125.
Lopez-Nevado, M, Ortiz-Martin, J, Serrano, C, Perez-Saez, MA, Lopez-Lorenzo, JL, Gil-Etayo, FJ, Rodriguez-Frias, E, Cabrera-Marante, O, Morales-Perez, P, Rodriguez-Pinilla, MS, Manso, R, Salgado-Sanchez, RN, Cerda-Montagud, A, Quesada-Espinosa, JF, Gomez-Rodriguez, MJ, Paz-Artal, E, Munoz-Calleja, C, Arranz-Saez, R, Allende, LM (2023).

Novel Germline TET2 Mutations in Two Unrelated Patients with Autoimmune Lymphoproliferative Syndrome-Like Phenotype and Hematologic Malignancy

JOURNAL OF CLINICAL IMMUNOLOGY. Article. 43(1):165-180.
[doi:10.1007/s10875-022-01361-y]
Santos Pérez de la Blanca R, Medina-Polo J, Peña-Vallejo H, Juste-Álvarez S, Pamplona-Casamayor M, Duarte-Ojeda JM, Miranda Utrera N, García-González L, Arrébola-Pajares A, Rodríguez Antolín A, Tejido-Sánchez Á (2023).

Ureteral Stenosis and Fistula after Kidney Transplantation.

UROLOGIA INTERNATIONALIS. Article. 107(2):1-8.
[doi:10.1159/000523690]

2022

Suarez-Cabrera, C, Estudillo, L, Ramon-Gil, E, Martinez-Fernandez, M, Peral, J, Rubio, C, Lodewijk, I, de Bernardo, AM, Garcia-Escudero, R, Villacampa, F, Duarte, J, de la Rosa, F, Castellano, D, Guerrero-Ramos, F, Real, FX, Malats, N, Paramio, JM, Duenas, M (2022).

BlaDimiR: A Urine-based miRNA Score for Accurate Bladder Cancer Diagnosis and Follow-up

EUROPEAN UROLOGY. Letter. 82(6):663-667.
[doi:10.1016/j.eururo.2022.08.011]
Errazquin R, Page A, Suñol A, Segrelles C, Carrasco E, Peral J, Garrido-Aranda A, Del Marro S, Ortiz J, Lorz C, Minguillon J, Surralles J, Belendez C, Alvarez M, Balmaña J, Bravo A, Ramirez A, Garcia-Escudero R (2022).

Development of a mouse model for spontaneous oral squamous cell carcinoma in Fanconi anemia.

ORAL ONCOLOGY. Article. 134:106184-106184.
[doi:10.1016/j.oraloncology.2022.106184]
González-Padilla DA, Subiela JD, González-Díaz A, Hernández-Arroyo M, García-Rojo E, Aumatell J, Burgos Revilla J, Rodríguez-Antolín A, Guerrero-Ramos F (2022).

Corrigendum to <'Mitomycin C allergy after passive and device-assisted hyperthermia for non-muscle invasive bladder cancer treatment: A retrospective cohort from a high-volume center'> <[Volume 40, Issue 7, July 2022, Pages 345.e19-345.e23]>.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS. Correction. 40(10):463-463.
[doi:10.1016/j.urolonc.2022.06.017]
Earl J, Calabuig-Fariñas S, Sarasquete ME, Muinelo Romay L, Lopez-Tarruella S, Bellosillo Paricio B, Rodríguez M, Valencia Leoz K, Dueñas Porto M, Tarazona N, Hernandez Losa J, Toledo RA (2022).

A Standardized Liquid Biopsy Preanalytical Protocol for Downstream Circulating-Free DNA Applications.

JOVE-JOURNAL OF VISUALIZED EXPERIMENTS. Article.
[doi:10.3791/64123]
Gómez-Rodríguez MJ, Morales-Conejo M, Arteche-López A, Sánchez-Calvín MT, Quesada-Espinosa JF, Gómez-Manjón I, Palma-Milla C, Lezana-Rosales JM, Pérez de la Fuente R, Martin-Ramos ML, Fernández-Guijarro M, Moreno-García M, Alvarez-Mora MI (2022).

Fragile X Syndrome Caused by Maternal Somatic Mosaicism of FMR1 Gene: Case Report and Literature Review.

Genes. Review. 13(9).
[doi:10.3390/genes13091609]
Rodrigo, JP, Rodriguez-Santamarta, T, Corte, D, Garcia-de-la-Fuente, V, Rodriguez-Torres, N, Lequerica-Fernandez, P, Lorz, C, Garcia-Pedrero, JM, de Vicente, JC (2022).

Hippo-YAP signaling activation and cross-talk with PI3K in oral cancer: A retrospective cohort study.

ORAL DISEASES. Article.
[doi:10.1111/odi.14350]
Velázquez-Lam E, Tome-Amat J, Segrelles C, Yuste-Calvo C, Asensio S, Peral J, Ponz F, Lorz C (2022).

Antitumor applications of polyphenol-conjugated turnip mosaic virus-derived nanoparticles.

NANOMEDICINE. Article. 17(14):999-1012.
[doi:10.2217/nnm-2022-0067]
de Velasco G, Carril-Ajuria L, Guerrero-Ramos F, Alonso-Gordoa T, Rodríguez-Moreno JF, Carretero A, Martin-Soberon M, de la Rosa-Kehrmann F, Castellano D (2022).

Addendum: A case series of advanced renal cell carcinoma patients treated with neoadjuvant cabozantinib prior to cytoreductive nephrectomy within the phase 2 CABOPRE trial.

Oncotarget. Correction. 13:983-983.
[doi:10.18632/oncotarget.28263]
Mayoral, IH, Martinez-Salio, A, Llamas-Velasco, S, Gomez-Majon, I, Arteche-Lopez, A, Quesada-Espinosa, JF, Milla, CP, Rosales, JML, de la Fuente, RP, Rufian, AJ, Tomillo, OS, Calvin, MTS, Rodriguez, MJG, Gomez, PR, Villarejo-Galende, A, Diaz-Guzman, J, Ortega-Casarrubios, MA, Calleja-Castano, P, Moreno-Garcia, M (2022).

Hereditary cerebral small vessel disease: Assessment of a HTRA1 variant using protein stability predictors and 3D modelling

European Journal of Medical Genetics. Article. 65(8):104539-104539.
[doi:10.1016/j.ejmg.2022.104539]
Lázaro S, Lorz C, Enguita AB, Seller I, Paramio JM, Santos M (2022).

Pten and p53 Loss in the Mouse Lung Causes Adenocarcinoma and Sarcomatoid Carcinoma.

Cancers. Article. 14(15).
[doi:10.3390/cancers14153671]
Montalbán-Hernández K, Cantero-Cid R, Casalvilla-Dueñas JC, Avendaño-Ortiz J, Marín E, Lozano-Rodríguez R, Terrón-Arcos V, Vicario-Bravo M, Marcano C, Saavedra-Ambrosy J, Prado-Montero J, Valentín J, Pérez de Diego R, Córdoba L, Pulido E, Del Fresno C, Dueñas M, López-Collazo E (2022).

Colorectal Cancer Stem Cells Fuse with Monocytes to Form Tumour Hybrid Cells with the Ability to Migrate and Evade the Immune System.

Cancers. Article. 14(14).
[doi:10.3390/cancers14143445]
Vallejo, EP, Sanchez, AT, Utrera, NM, del Canizo, CG (2022).

Massive Hydronephrosis, Countless Lithiasis and Upper Urinary Tract Carcinoma

UROLOGY. Editorial Material. 165:7-8.
[doi:10.1016/j.urology.2022.03.024]
Gonzalez-Padilla, DA, Subiela, JD, Gonzalez-Diaz, A, Hernandez-Arroyo, M, Garcia-Rojo, E, Aumatell, J, Revilla, JB, Rodriguez-Antolin, A, Guerrero-Ramos, F (2022).

Mitomycin C allergy after passive and device-assisted hyperthermia for non-muscle invasive bladder cancer treatment: A retrospective cohort from a high-volume center

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS. Article. 40(7).
[doi:10.1016/j.urolonc.2022.02.018]
Duréndez-Sáez E, Calabuig-Fariñas S, Torres-Martínez S, Moreno-Manuel A, Herreros-Pomares A, Escorihuela E, Mosqueda M, Gallach S, Guijarro R, Serna E, Suárez-Cabrera C, Paramio JM, Blasco A, Camps C, Jantus-Lewintre E (2022).

Analysis of Exosomal Cargo Provides Accurate Clinical, Histologic and Mutational Information in Non-Small Cell Lung Cancer.

Cancers. Article. 14(13).
[doi:10.3390/cancers14133216]
Moreira-Silva F, Outeiro-Pinho G, Lobo J, Guimarães R, Gaspar VM, Mano JF, Agirre X, Pineda-Lucena A, Prosper F, Paramio JM, Henrique R, Correia MP, Jerónimo C (2022).

G9a inhibition by CM-272: Developing a novel anti-tumoral strategy for castration-resistant prostate cancer using 2D and 3D in vitro models.

BIOMEDICINE & PHARMACOTHERAPY. Article. 150:113031-113031.
[doi:10.1016/j.biopha.2022.113031]
Morales, L, Oliveros, JC, Enjuanes, L, Sola, I (2022).

Contribution of Host miRNA-223-3p to SARS-CoV-Induced Lung Inflammatory Pathology

Mbio. Article. 13(2).
[doi:10.1128/mbio.03135-21]
González-Padilla DA, García-Rojo E, Abad-López P, Guerrero-Ramos F (2022).

Metastatic testicular cancer presenting with hematuria and flank pain.

Urology annals. Article. 14(2):196-198.
[doi:10.4103/UA.UA_63_20]
Alvarez-Mora, MI, Blanco-Palmero, VA, Quesada-Espinosa, JF, Arteche-Lopez, AR, Llamas-Velasco, S, Milla, CP, Rosales, JML, Gomez-Manjon, I, Hernandez-Lain, A, Almonacid, JJ, Gil-Fournier, B, Ramiro-Leon, S, Gonzalez-Sanchez, M, Herrero-San Martin, AO, Perez-Martinez, DA, Gomez-Tortosa, E, Carro, E, Bartolome, F, Gomez-Rodriguez, MJ, Sanchez-Calvin, MT, Villarejo-Galende, A, Moreno-Garcia, M (2022).

Heterozygous and Homozygous Variants in SORL1 Gene in Alzheimer's Disease Patients: Clinical, Neuroimaging and Neuropathological Findings

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 23(8).
[doi:10.3390/ijms23084230]
Guerrero-Ramos, F, Gonzalez-Padilla, DA, Gonzalez-Diaz, A, de la Rosa-Kehrmann, F, Rodriguez-Antolin, A, Inman, BA, Villacampa-Auba, F (2022).

Recirculating hyperthermic intravesical chemotherapy with mitomycin C (HIVEC) versus BCG in high-risk non-muscle-invasive bladder cancer: results of the HIVEC-HR randomized clinical trial

WORLD JOURNAL OF UROLOGY. Article. 40(4):999-1004.
[doi:10.1007/s00345-022-03928-1]
Lodewijk I, Bernardini A, Suárez-Cabrera C, Bernal E, Sánchez R, Garcia JL, Rojas K, Morales L, Wang S, Han X, Dueñas M, Paramio JM, Manso L (2022).

Genomic landscape and immune-related gene expression profiling of epithelial ovarian cancer after neoadjuvant chemotherapy.

npj Precision Oncology. Article. 6(1):7-7.
[doi:10.1038/s41698-021-00247-3]
García-García VA, Alameda JP, Page A, Mérida-García A, Navarro M, Tejero A, Paramio JM, García-Fernández RA, Casanova ML (2022).

IKKa Induces Epithelial-Mesenchymal Changes in Mouse Skin Carcinoma Cells That Can Be Partially Reversed by Apigenin.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 23(3).
[doi:10.3390/ijms23031375]
Bernardini A, Dueñas M, Martín-Soberon MC, Rubio C, Suarez-Cabrera C, Ruiz-Palomares R, Munera-Maravilla E, Lázaro S, Lodewijk I, Rueda D, Gómez-Sánchez D, Alonso-Gordoa T, Puente J, Pinto Á, González-Peramato P, Aguado C, Herrera M, López F, Martinez VMG, Morales L, Castellano D, Paramio JM, de Velasco G (2022).

Genomic Landscape of Vinflunine Response in Metastatic Urothelial Cancer.

Cancers. Article. 14(2).
[doi:10.3390/cancers14020378]
Rubio C, Avendaño-Ortiz J, Ruiz-Palomares R, Karaivanova V, Alberquilla O, Sánchez-Domínguez R, Casalvilla-Dueñas JC, Montalbán-Hernández K, Lodewijk I, Rodríguez-Izquierdo M, Munera-Maravilla E, Nunes SP, Suárez-Cabrera C, Pérez-Crespo M, Martínez VG, Morales L, Pérez-Escavy M, Alonso-Sánchez M, Lozano-Rodríguez R, Cueto FJ, Aguirre LA, Guerrero-Ramos F, Paramio JM, López-Collazo E, Dueñas M (2022).

Toward Tumor Fight and Tumor Microenvironment Remodeling: PBA Induces Cell Cycle Arrest and Reduces Tumor Hybrid Cells' Pluripotency in Bladder Cancer.

Cancers. Article. 14(2).
[doi:10.3390/cancers14020287]
Tan, WP, Bello, AP, Alvarez, CG, Guerrero-Ramos, F, Gonzalez-Padilla, DA, Nzeh, C, De la Morena, JM, De Torres, IGV, Hendricksen, K, Goizueta, FJD, Del Alamo, JF, Chiancone, F, Fedelini, P, Poggio, M, Porpiglia, F, Rodriguez, VCG, Torres, JM, Wilby, D, Robinson, R, Sousa-Escandon, A, Mata, JL, Moreno, JLP, Molina, FD, Semino, MAA, Stemberger, AT, Escudero, JC, Redorta, JP, Tan, WS (2022).

A Multicenter Study of 2-year Outcomes Following Hyperthermia Therapy with Mitomycin C in Treating Non-Muscle Invasive Bladder Cancer: HIVEC-E

Bladder Cancer. Article. 8(4):379-393.
[doi:10.3233/BLC-220026]
Guerrero-Ramos, F, Subiela, JD, Rodriguez-Faba, O, Aumatell, J, Manfredi, C, Bozzini, G, Romero-Otero, J, Counago, F (2022).

Predicting Recurrence and Progression in Patients with Non-Muscle-Invasive Bladder Cancer: Systematic Review on the Performance of Risk Stratification Models

Bladder Cancer. Review. 8(4):339-357.
[doi:10.3233/BLC-220055]

2021

Sanchez, AT, Casamayor, MP, Ojeda, JMD, Polo, JM, Utrera, NRM, Gonzalez, LG, Pajares, AA, Antolin, AR (2021).

TREATMENT OF LATE COMPLICATIONS OF RENAL TRANSPLANTATION

ARCHIVOS ESPANOLES DE UROLOGIA. Article. 74(10):1040-1049.
Tejido Sánchez A, Pamplona Casamayor M, Duarte Ojeda JM, Medina Polo J, Miranda Utrera NR, García González L, Arrébola Pajares A, Rodríguez Antolín A (2021).

Tratamiento de las complicaciones tardías del trasplante renal.

ARCHIVOS ESPANOLES DE UROLOGIA. Article. 74(10):1040-1049.
Zhao H, Chan VW, Castellani D, Chan EO, Ong WLK, Peng Q, Moschini M, Krajewski W, Pradere B, Ng CF, Enikeev D, Vasdev N, Ekin G, Sousa A, Leon J, Guerrero-Ramos F, Tan WS, Kelly J, Shariat SF, Witjes JA, Teoh JY (2021).

Intravesical Chemohyperthermia vs. Bacillus Calmette-Guerin Instillation for Intermediate- and High-Risk Non-muscle Invasive Bladder Cancer: A Systematic Review and Meta-Analysis.

Frontiers in Surgery. Review. 8:775527-775527.
[doi:10.3389/fsurg.2021.775527]
Pernas, S, Villagrasa, P, Vivancos, A, Scaltriti, M, Rodon, J, Burgues, O, Nuciforo, P, Canes, J, Pare, L, Dueñas M, Vidal, M, Cejalvo, JM, Perello, A, Llommbard-Cussac, A, Dorca, J, Montaño A, Pascual, T, Oliveira, M, Ribas, G, Rapado, I, Prat, A, Ciruelos, E (2021).

First Nationwide Molecular Screening Program in Spain for Patients With Advanced Breast Cancer: Results From the AGATA SOLTI-1301 Study.

Frontiers in oncology. Article. 11:744112-744112.
[doi:10.3389/fonc.2021.744112]
Suarez-Cabrera, C, Ojeda-Perez, I, Sanchez-Baltasar, R, Page, A, Bravo, A, Navarro, M, Ramirez, A (2021).

ERAS, a Member of the Ras Superfamily, Acts as an Oncoprotein in the Mammary Gland

Cancers. Article. 13(21).
[doi:10.3390/cancers13215588]
Plata, A, Guerrero-Ramos, F, Garcia, C, Gonzalez-Diaz, A, Gonzalez-Valcarcel, I, de la Morena, JM, Diaz-Goizueta, FJ, del Alamo, JF, Gonzalo, V, Montero, J, Sousa-Escandon, A, Leon, J, Pontones, JL, Delgado, F, Adriazola, M, Pascual, A, Calleja, J, Ruano, A, Martinez-Pineiro, L, Angulo, JC (2021).

Long-Term Experience with Hyperthermic Chemotherapy (HIVEC) Using Mitomycin-C in Patients with Non-Muscle Invasive Bladder Cancer in Spain

Journal of Clinical Medicine. Article. 10(21).
[doi:10.3390/jcm10215105]
Quesada-Espinosa, JF, Garzon-Lorenzo, L, Lezana-Rosales, JM, Gomez-Rodriguez, MJ, Sanchez-Calvin, MT, Palma-Milla, C, Gomez-Manjon, I, Hidalgo-Mayoral, I, de la Fuente, RP, Arteche-Lopez, A, Alvarez-Mora, MI, Camacho-Salas, A, Cruz-Rojo, J, Lazaro-Rodriguez, I, Morales-Conejo, M, Nunez-Enamorado, N, Bustamante-Aragones, A, de las Heras, RS, Gomez-Cano, MA, Ramos-Gomez, P, Sierra-Tomillo, O, Juarez-Rufian, A, Gallego-Merlo, J, Rausell-Sanchez, L, Moreno-Garcia, M, del Pozo, JS (2021).

First female with Allan-Herndon-Dudley syndrome and partial deletion of X-inactivation center

NEUROGENETICS. Article. 22(4):343-346.
[doi:10.1007/s10048-021-00660-7]
Arteche-López A, Álvarez-Mora MI, Sánchez Calvin MT, Lezana Rosales JM, Palma Milla C, Gómez Rodríguez MJ, Gomez Manjón I, Blázquez A, Juarez Rufián A, Ramos Gómez P, Sierra Tomillo O, Hidalgo Mayoral I, Pérez de la Fuente R, Posada Rodríguez IJ, González Granado LI, Martin MA, Quesada-Espinosa JF, Moreno-García M (2021).

Biallelic variants in genes previously associated with dominant inheritance: CACNA1A, RET and SLC20A2.

EUROPEAN JOURNAL OF HUMAN GENETICS. Article. 29(10):1520-1526.
[doi:10.1038/s41431-021-00919-5]
Bedke J, Merseburger AS, Loriot Y, Castellano D, Choy E, Duran I, Rosenberg JE, Petrylak DP, Dreicer R, Perez-Gracia JL, Hoffman-Censits JH, Van Der Heijden MS, Pavlova J, Thiebach L, de Ducla S, Fear S, Powles T, Sternberg CN (2021).

Partial Response and Stable Disease Correlate with Positive Outcomes in Atezolizumab-treated Patients with Advanced Urinary Tract Carcinoma.

European Urology Focus. Article. 7(5):1084-1091.
[doi:10.1016/j.euf.2020.10.009]
Fankhauser CD, Tran B, Pedregal M, Ruiz-Morales JM, Gonzalez-Billalabeitia E, Patrikidou A, Amir E, Seidel C, Bokemeyer C, Hermanns T, Rumyantsev A, Tryakin A, Brito M, Fléchon A, Kwan EM, Cheng T, Castellano D, Del Muro XG, Hamid AA, Ottaviano M, Palmieri G, Kitson R, Reid A, Heng DYC, Bedard PL, Sweeney CJ, Connors JM (2021).

A Risk-benefit Analysis of Prophylactic Anticoagulation for Patients with Metastatic Germ Cell Tumours Undergoing First-line Chemotherapy.

European Urology Focus. Article. 7(5):1130-1136.
[doi:10.1016/j.euf.2020.09.017]
Medina-Polo J, Gil-Moradillo J, González-Díaz A, Abad-López P, Santos-Pérez de la Blanca R, Hernández-Arroyo M, Peña-Vallejo H, Téigell-Tobar J, Calzas-Montalvo C, Caro-González P, Miranda-Utrera N, Tejido-Sánchez Á (2021).

Observational study over 8-year period evaluating microbiological characteristics and risk factor for isolation of multidrug-resistant organisms (MDRO) in patients with healthcare-associated infections (HAIs) hospitalized in a urology ward.

Gms Infectious Diseases. Article. 9.
[doi:10.3205/id000073]
Elorza A, Márquez Y, Cabrera JR, Sánchez-Trincado JL, Santos-Galindo M, Hernández IH, Picó S, Díaz-Hernández JI, García-Escudero R, Irimia M, Lucas JJ (2021).

Huntington's disease-specific mis-splicing unveils key effector genes and altered splicing factors.

BRAIN. Article. 144(7):2009-2023.
[doi:10.1093/brain/awab087]
Suzuki, H, Castellano, D, de Bono, J, Sternberg, CN, Fizazi, K, Tombal, B, Wulfing, C, Foster, MC, Ozatilgan, A, Geffriaud-Ricouard, C, de Wit, R (2021).

Cabazitaxel versus abiraterone or enzalutamide in metastatic castration-resistant prostate cancer: post hoc analysis of the CARD study excluding chemohormonal therapy for castrate-naive disease

JAPANESE JOURNAL OF CLINICAL ONCOLOGY. Article. 51(8):1287-1297.
[doi:10.1093/jjco/hyab028]
Esagian, SM, Khaki, AR, Diamantopoulos, LN, Carril-Ajuria, L, Castellano, D, De Kouchkovsky, I, Park, JJ, Alva, A, Bilen, MA, Stewart, TF, McKay, RR, Santos, VS, Agarwal, N, Jain, J, Zakharia, Y, Morales-Barrera, R, Devitt, ME, Nelson, A, Hoimes, CJ, Shreck, E, Gartrell, BA, Sankin, A, Tripathi, A, Zakopoulou, R, Bamias, A, Rodriguez-Vida, A, Drakaki, A, Liu, S, Kumar, V, Lythgoe, MP, Pinato, DJ, Murgic, J, Fröbe A, Joshi, M, Isaacsson Velho P, Hahn, N, Alonso Buznego L, Duran, I, Moses, M, Barata, P, Galsky, MD, Sonpavde, G, Yu, EY, Msaouel, P, Koshkin, VS, Grivas, P (2021).

Immune checkpoint inhibitors in advanced upper and lower tract urothelial carcinoma: a comparison of outcomes

BJU INTERNATIONAL. Article. 128(2):196-205.
[doi:10.1111/bju.15324]
Merseburger AS, Castellano D, Powles T, Loriot Y, Retz M, Voortman J, Huddart RA, Gedye C, Van Der Heijden MS, Gurney H, Ong M, de Ducla S, Pavlova J, Fear S, Sternberg CN (2021).

Safety and Efficacy of Atezolizumab in Understudied Populations with Pretreated Urinary Tract Carcinoma: Subgroup Analyses of the SAUL Study in Real-World Practice.

JOURNAL OF UROLOGY. Article. 206(2):240-251.
[doi:10.1097/JU.0000000000001768]
de Velasco G, Ruiz-Granados Á, Reig O, Massari F, Climent Duran MA, Verzoni E, Graham J, Llarena R, De Tursi M, Donskov F, Iglesias C, Pandha HS, Garcia Del Muro X, Procopio G, Oudard S, Castellano D, Albiges L (2021).

Outcomes of systemic targeted therapy in recurrent renal cell carcinoma treated with adjuvant sunitinib.

BJU INTERNATIONAL. Article. 128(2):254-261.
[doi:10.1111/bju.15356]
Wells JC, Dudani S, Gan CL, Stukalin I, Azad AA, Liow E, Donskov F, Yuasa T, Pal SK, De Velasco G, Hansen AR, Beuselinck B, Kollmannsberger CK, Powles T, McGregor BA, Duh MS, Huynh L, Heng DYC (2021).

Clinical Effectiveness of Second-line Sunitinib Following Immuno-oncology Therapy in Patients with Metastatic Renal Cell Carcinoma: A Real-world Study.

CLINICAL GENITOURINARY CANCER. Article. 19(4):354-361.
[doi:10.1016/j.clgc.2021.03.006]
Canllavi E, Teigell J, Trujillo H, Gutiérrez E, Sánchez A, Miranda-Utrera N, Morales E (2021).

Acute Page kidney after angioplasty in kidney transplant allografts.

Clinical kidney journal. Editorial Material. 14(8):1980-1982.
[doi:10.1093/ckj/sfab064]
Garcia-Garcia, VA, Alameda, JP, Page, A, Casanova, ML (2021).

Role of NF-kappa B in Ageing and Age-Related Diseases: Lessons from Genetically Modified Mouse Models

Cells. Review. 10(8).
[doi:10.3390/cells10081906]
García-Escudero V, Ruiz-Gabarre D, Gargini R, Pérez M, García E, Cuadros R, Hernández IH, Cabrera JR, García-Escudero R, Lucas JJ, Hernández F, Ávila J (2021).

A new non-aggregative splicing isoform of human Tau is decreased in Alzheimer's disease.

ACTA NEUROPATHOLOGICA. Article. 142(1):159-177.
[doi:10.1007/s00401-021-02317-z]
Alameda, JP, Garcia-Garcia, VA, Lopez, S, Hernando, A, Page, A, Navarro, M, Moreno-Maldonado, R, Paramio, JM, Ramirez, A, Garcia-Fernandez, RA, Casanova, ML (2021).

CYLD Inhibits the Development of Skin Squamous Cell Tumors in Immunocompetent Mice

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 22(13).
[doi:10.3390/ijms22136736]
Araujo DV, Wells JC, Hansen AR, Dizman N, Pal SK, Beuselinck B, Donskov F, Gan CL, Yan F, Tran B, Kollmannsberger CK, de Velasco G, Yuasa T, Reaume MN, Ernst DS, Powles T, Bjarnason GA, Choueiri TK, Heng DYC, Dudani S (2021).

Efficacy of immune-checkpoint inhibitors (ICI) in the treatment of older adults with metastatic renal cell carcinoma (mRCC) - an International mRCC Database Consortium (IMDC) analysis.

JOURNAL OF GERIATRIC ONCOLOGY. Article. 12(5):820-826.
[doi:10.1016/j.jgo.2021.02.022]
Khaki AR, Li A, Diamantopoulos LN, Miller NJ, Carril-Ajuria L, Castellano D, De Kouchkovsky I, Koshkin V, Park J, Alva A, Bilen MA, Stewart T, Santos V, Agarwal N, Jain J, Zakharia Y, Morales-Barrera R, Devitt M, Nelson A, Hoimes CJ, Shreck E, Gartrell BA, Sankin A, Tripathi A, Zakopoulou R, Bamias A, Rodriguez-Vida A, Drakaki A, Liu S, Kumar V, Lythgoe MP, Pinato DJ, Murgic J, Fröbe A, Joshi M, Isaacsson Velho P, Hahn N, Alonso Buznego L, Duran I, Moses M, Barata P, Galsky MD, Sonpavde G, Yu EY, Shankaran V, Lyman GH, Grivas P (2021).

A New Prognostic Model in Patients with Advanced Urothelial Carcinoma Treated with First-line Immune Checkpoint Inhibitors.

European Urology Oncology. Article. 4(3):464-472.
[doi:10.1016/j.euo.2020.12.006]
Vallina C, López-Pintor RM, González-Serrano J, de Vicente JC, Hernández G, Lorz C (2021).

Genes involved in the epithelial-mesenchymal transition in oral cancer: A systematic review.

ORAL ONCOLOGY. Review. 117:105310-105310.
[doi:10.1016/j.oraloncology.2021.105310]
González-Padilla DA, González-Díaz A, García-Rojo E, Abad-López P, Santos-Pérez de la Blanca R, Hernández-Arroyo M, Teigell-Tobar J, Peña-Vallejo H, Rodríguez-Antolín A, Cabrera-Meirás F (2021).

Analgesic refractory colic pain: Is prolonged conservative management appropriate?

AMERICAN JOURNAL OF EMERGENCY MEDICINE. Article. 44:137-142.
[doi:10.1016/j.ajem.2021.02.018]
de la Blanca, RSP, Medina-Polo, J, Pena-Vallejo, E, Pamplona-Casamayor, M, Teigell-Tobar, J, Hernandez-Arroyo, M, Duarte-Ojeda, JM, Tejido-Sanchez, A, Cabrera-Meiras, F, Miranda-Utrera, N, Garcia-Gonzalez, L, Gonzalez-Monte, E, Rodriguez-Antolin, A (2021).

Iterative renal transplantation: our experience on third transplants

INTERNATIONAL UROLOGY AND NEPHROLOGY. Article. 53(6):1097-1104.
[doi:10.1007/s11255-021-02788-9]
Szabados B, Rodriguez-Vida A, Durán I, Crabb SJ, Van Der Heijden MS, Pous AF, Gravis G, Herranz UA, Protheroe A, Ravaud A, Maillet D, Mendez-Vidal MJ, Suárez C, Linch M, Prendergast A, Tyson C, Mousa K, Castellano D, Powles T (2021).

Toxicity and Surgical Complication Rates of Neoadjuvant Atezolizumab in Patients with Muscle-invasive Bladder Cancer Undergoing Radical Cystectomy: Updated Safety Results from the ABACUS Trial.

European Urology Oncology. Article. 4(3):456-463.
[doi:10.1016/j.euo.2020.11.010]
De Borbon, ECD, Vales, JMG, Bermejo, CL, Ramos, FG, Padilla, MJB, de la Aleja, JG, Conejo, MM (2021).

Clinical, genetic and quality-of-life study of a cohort of adult patients with tuberous sclerosis

ORPHANET JOURNAL OF RARE DISEASES. Article. 16(1).
[doi:10.1186/s13023-021-01878-2]
Rojo EG, Gómez BG, de la Blanca RSP, Manfredi C, Isa MA, Polo JM, Antolín AR, Otero JR (2021).

Role of neutrophil-to-lymphocyte and platelet-to-lymphocyte ratios in Peyronie's disease: a new diagnostic approach to predict the stage of the disease?

ASIAN JOURNAL OF ANDROLOGY. Article. 23(3):325-329.
[doi:10.4103/aja.aja_74_20]
Baltanás FC, Mucientes-Valdivieso C, Lorenzo-Martín LF, Fernández-Parejo N, García-Navas R, Segrelles C, Calzada N, Fuentes-Mateos R, Paramio JM, Bustelo XR, Santos E (2021).

Functional Specificity of the Members of the Sos Family of Ras-GEF Activators: Novel Role of Sos2 in Control of Epidermal Stem Cell Homeostasis.

Cancers. Article. 13(9).
[doi:10.3390/cancers13092152]
Errazquin R, Sieiro E, Moreno P, Ramirez MJ, Lorz C, Peral J, Ortiz J, Casado JA, Roman-Rodriguez FJ, Hanenberg H, Río P, Surralles J, Segrelles C, Garcia-Escudero R (2021).

Generating New FANCA-Deficient HNSCC Cell Lines by Genomic Editing Recapitulates the Cellular Phenotypes of Fanconi Anemia.

Genes. Article. 12(4).
[doi:10.3390/genes12040548]
García-Rojo E, Manfredi C, Santos-Pérez-de-la-Blanca R, Tejido-Sánchez Á, García-Gómez B, Aliaga-Benítez M, Romero-Otero J, Rodriguez-Antolín A (2021).

Impact of COVID-19 outbreak on urology surgical waiting lists and waiting lists prioritization strategies in the Post-COVID-19 era.

ACTAS UROLOGICAS ESPANOLAS. Article. 45(3):207-214.
[doi:10.1016/j.acuro.2020.11.001]
Santos, M, Lanillos, J, Roldan-Romero, JM, Caleiras, E, Montero-Conde, C, Cascon, A, Climent, MA, Anguera, G, Hernando, S, Lainez, N, Robledo, M, Robles, L, de Velasco, G, Garcia-Donas, J, Rodriguez-Antona, C (2021).

Prevalence of pathogenic germline variants in patients with metastatic renal cell carcinoma

GENETICS IN MEDICINE. Article. 23(4):698-704.
[doi:10.1038/s41436-020-01062-0]
Carril-Ajuria L, Lora D, Carretero-González A, Martín-Soberón M, Rioja-Viera P, Castellano D, de Velasco G (2021).

Systemic Analysis and Review of Nivolumab-ipilimumab Combination as a Rescue Strategy for Renal Cell Carcinoma After Treatment With Anti-PD-1/PD-L1 Therapy.

CLINICAL GENITOURINARY CANCER. Review. 19(2):95-102.
[doi:10.1016/j.clgc.2020.10.004]
Sotelo M, Alonso-Gordoa T, Gajate P, Gallardo E, Morales-Barrera R, Pérez-Gracia JL, Puente J, Sánchez P, Castellano D, Durán I (2021).

Atezolizumab in locally advanced or metastatic urothelial cancer: a pooled analysis from the Spanish patients of the IMvigor 210 cohort 2 and 211 studies

CLINICAL & TRANSLATIONAL ONCOLOGY. Article. 23(4):882-891.
[doi:10.1007/s12094-020-02482-9]
Bellmunt J, Hussain M, Gschwend JE, Albers P, Oudard S, Castellano D, Daneshmand S, Nishiyama H, Majchrowicz M, Degaonkar V, Shi Y, Mariathasan S, Grivas P, Drakaki A, O'Donnell PH, Rosenberg JE, Geynisman DM, Petrylak DP, Hoffman-Censits J, Bedke J, Kalebasty AR, Zakharia Y, van der Heijden MS, Sternberg CN, Davarpanah NN, Powles T, IMvigor010 Study Group (2021).

Adjuvant atezolizumab versus observation in muscle-invasive urothelial carcinoma (IMvigor010): a multicentre, open-label, randomised, phase 3 trial.

LANCET ONCOLOGY. Article. 22(4):525-537.
[doi:10.1016/S1470-2045(21)00004-8]
Arteche-Lopez, A, Rodriguez, MJG, Calvin, MTS, Quesada-Espinosa, JF, Rosales, JML, Milla, CP, Gomez-Manjon, I, Mayoral, IH, de la Fuente, RP, de Bustamante, AD, Darnaude, MT, Gil-Fournier, B, Leon, SR, Gomez, PR, Tomillo, OS, Rufian, AJ, Cano, MIA, Alonso, RV, Morales-Perez, P, Segura-Tudela, A, Camacho, A, Nunez, N, Simon, R, Moreno-Garcia, M, Alvarez-Mora, MI (2021).

Towards a Change in the Diagnostic Algorithm of Autism Spectrum Disorders: Evidence Supporting Whole Exome Sequencing as a First-Tier Test

Genes. Article. 12(4).
[doi:10.3390/genes12040560]
García-Gómez B, García-Rojo E, Alonso-Isa M, Medina-Polo J, Santos-Pérez de la Blanca R, Justo-Quintas J, Parnham A, Rodríguez-Antolín A, Romero-Otero J (2021).

Treatment of peyronie's disease with combination of clostridium histolyticum collagenase and penile traction therapy: a prospective, multicenter, single-arm study

INTERNATIONAL JOURNAL OF IMPOTENCE RESEARCH. Article. 33(3):325-331.
[doi:10.1038/s41443-020-0292-y]
Powles T, Rosenberg JE, Sonpavde GP, Loriot Y, Durán I, Lee JL, Matsubara N, Vulsteke C, Castellano D, Wu C, Campbell M, Matsangou M, Petrylak DP (2021).

Enfortumab Vedotin in Previously Treated Advanced Urothelial Carcinoma.

NEW ENGLAND JOURNAL OF MEDICINE. Article. 384(12):1125-1135.
[doi:10.1056/NEJMoa2035807]
Lodewijk I, Nunes SP, Henrique R, Jerónimo C, Dueñas M, Paramio JM (2021).

Tackling tumor microenvironment through epigenetic tools to improve cancer immunotherapy.

Clinical epigenetics. Review. 13(1):63-63.
[doi:10.1186/s13148-021-01046-0]
McDermott DF, Lee JL, Ziobro M, Suarez C, Langiewicz P, Matveev VB, Wiechno P, Gafanov RA, Tomczak P, Pouliot F, Donskov F, Alekseev BY, Shin SJ, Bjarnason GA, Castellano D, Silverman RK, Perini RF, Schloss C, Atkins MB (2021).

Open-Label, Single-Arm, Phase II Study of Pembrolizumab Monotherapy as First-Line Therapy in Patients With Advanced Non-Clear Cell Renal Cell Carcinoma.

JOURNAL OF CLINICAL ONCOLOGY. Article. 39(9):1029-1039.
[doi:10.1200/JCO.20.02365]
Sopeña Sutil R, Silva Ruiz J, Garcia Gomez B, Romero-Otero J, Garcia-Gonzalez L, Duarte Ojeda JM, de Velasco G, Castellano Gauna D, Rodriguez Antolin A (2021).

Seizures and Neuropsychiatric Toxicity in Patients with Non-Metastatic CRPC Treated with New Antiandrogens: Systematic Review and Meta-Analysis.

ONCOLOGY RESEARCH AND TREATMENT. Review. 44(4):154-163.
[doi:10.1159/000515014]
Morales L, Paramio JM (2021).

Cell Therapies in Bladder Cancer Management.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 22(6).
[doi:10.3390/ijms22062818]
Martín-Soberón MC, Ruiz S, De Velasco G, Yarza R, Carretero A, Castellano D, Sepúlveda-Sánchez JM (2021).

Pneumatosis intestinalis in a radioactive iodine-refractory metastasic thyroid papillary carcinoma with BRAF(V600E) mutation treated with dabrafenib-trametinib: a case report.

Journal Of Medical Case Reports. Article. 15(1):109-109.
[doi:10.1186/s13256-020-02581-9]
García-Rojo E, Medina-Polo J, Miranda-Utrera N, Abad-López P, Gonzalez-Padilla DA, González-Díaz A, Arrébola-Pajares A, Guerrero-Ramos F, Tejido-Sánchez Á, Rodríguez-Antolín A (2021).

Evaluation of health care-associated infections following radical cystectomy.

ACTAS UROLOGICAS ESPANOLAS. Article. 45(2):124-131.
[doi:10.1016/j.acuro.2020.06.004]
Álvarez-Maestro M, Guerrero-Ramos F, Rodríguez-Faba O, Domínguez-Escrig JL, Fernández-Gómez JM (2021).

Current treatments for BCG failure in non-muscle invasive bladder cancer (NMIBC).

Actas Urologicas Espanolas. Review. 45(2):93-102.
[doi:10.1016/j.acuro.2020.08.003]
Fernández-Montes A, de Velasco G, Aguín S, Farriols C, Guirado-Risueño M, Jerviz-Guía VG, Baeza-Nadal MV, Chicas-Sett R, Fírvida JL, García-Navalón F, Martín P, Perezagua-Marín C, Rodríguez D, Santamaría J, Saurí T, Cobo M (2021).

Insights into the Use of Peripherally Acting µ-Opioid Receptor Antagonists (PAMORAs) in Oncologic Patients: from Scientific Evidence to Real Clinical Practice.

CURRENT TREATMENT OPTIONS IN ONCOLOGY. Review. 22(3):26-26.
[doi:10.1007/s11864-021-00816-5]
Carretero-González A, Otero I, Lora D, Carril-Ajuria L, Castellano D, de Velasco G (2021).

Efficacy and safety of anti-PD-1/PD-L1 combinations versus standard of care in cancer: a systematic review and meta-analysis.

OncoImmunology. Review. 10(1):1878599-1878599.
[doi:10.1080/2162402X.2021.1878599]
Gan, CL, Dudani, S, Wells, JC, Donskov, F, Pal, SK, Dizman, N, Rathi, N, Beuselinck, B, Yan, F, Lalani, AKA, Hansen, A, Szabados, B, de Velasco, G, Tran, B, Lee, JL, Vaishampayan, UN, Bjarnason, GA, Subasri, M, Choueiri, TK, Heng DYC (2021).

Cabozantinib real-world effectiveness in the first-through fourth-line settings for the treatment of metastatic renal cell carcinoma: Results from the International Metastatic Renal Cell Carcinoma Database Consortium

Cancer Medicine. Article. 10(4):1212-1221.
[doi:10.1002/cam4.3717]
Wei, XX, Werner, L, Teo, MY, Rosenberg, JE, Koshkin, VS, Grivas, P, Szabados, B, Morrison, L, Powles, T, Carril-Ajuria, L, Castellano, D, Velho, PI, Hahn, NM, McKay, RR, Raggi, D, Necchi, A, Kanesvaran, R, Alerasool, P, Gaines, J, Galsky, M, Bellmunt, J, Sonpavde, G (2021).

Sequencing of PD-1/L1 Inhibitors and Carboplatin Based Chemotherapy for Cisplatin Ineligible Metastatic Urothelial Carcinoma

JOURNAL OF UROLOGY. Article. 205(2):414-419.
[doi:10.1097/JU.0000000000001371]
Moreno-Garcia, M, Arteche-Lopez, AR, Alvarez-Mora, MI, Milla, CP, Espinosa, JFQ, Rosales, JML, Calvin, MTS, Manjon, IG, Rodriguez, MJG, Mendez-Guerrero, A, Villarejo-Galende, A (2021).

First patient with mosaic NOTCH3 gene pathogenic variant. Unrevealed mosaicisms and importance of their detection

AMERICAN JOURNAL OF MEDICAL GENETICS PART A. Article. 185(2):591-595.
[doi:10.1002/ajmg.a.61999]
Graham J, Shah AY, Wells JC, McKay RR, Vaishampayan U, Hansen A, Donskov F, Bjarnason GA, Beuselinck B, De Velasco G, Iafolla M, Duh MS, Huynh L, Chang R, Zanotti G, Ramaswamy K, Choueiri TK, Tannir NM, Heng DYC (2021).

Outcomes of Patients with Metastatic Renal Cell Carcinoma Treated with Targeted Therapy After Immuno-oncology Checkpoint Inhibitors.

European Urology Oncology. Article. 4(1):102-111.
[doi:10.1016/j.euo.2019.11.001]
Rey-Cárdenas M, Guerrero-Ramos F, Gómez de Liaño Lista A, Carretero-González A, Bote H, Herrera-Juárez M, Carril-Ajuria L, Martín-Soberón M, Sepulveda JM, Billalabeitia EG, Castellano D, de Velasco G (2021).

Recent advances in neoadjuvant immunotherapy for urothelial bladder cancer: What to expect in the near future.

CANCER TREATMENT REVIEWS. Review. 93:102142-102142.
[doi:10.1016/j.ctrv.2020.102142]
Dudani, S, de Velasco, G, Wells, JC, Gan, CL, Donskov, F, Porta, C, Fraccon, A, Pasini, F, Lee, JL, Hansen, A, Bjarnason, GA, Beuselinck, B, Pal, SK, Yuasa, T, Kroeger, N, Kanesvaran, R, Reaume, MN, Canil, C, Choueiri, TK, Heng DYC (2021).

Evaluation of Clear Cell, Papillary, and Chromophobe Renal Cell Carcinoma Metastasis Sites and Association With Survival

Jama Network Open. Article. 4(1).
[doi:10.1001/jamanetworkopen.2020.21869]
Guccini I, Revandkar A, D'Ambrosio M, Colucci M, Pasquini E, Mosole S, Troiani M, Brina D, Sheibani-Tezerji R, Elia AR, Rinaldi A, Pernigoni N, Rüschoff JH, Dettwiler S, De Marzo AM, Antonarakis ES, Borrelli C, Moor AE, Garcia-Escudero R, Alajati A, Attanasio G, Losa M, Moch H, Wild P, Egger G, Alimonti A (2021).

Senescence Reprogramming by TIMP1 Deficiency Promotes Prostate Cancer Metastasis.

CANCER CELL. Article. 39(1):68.
[doi:10.1016/j.ccell.2020.10.012]
González-Padilla DA, González-Díaz A, Guerrero-Ramos F, Rodríguez-Serrano A, García-Jarabo E, Corona-laPuerta M, Rodríguez-Antolín A, Villacampa-Aubá F (2021).

Quality of life and adverse events in patients with nonmuscle invasive bladder cancer receiving adjuvant treatment with BCG, MMC, or chemohyperthermia

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS. Article. 39(1).
[doi:10.1016/j.urolonc.2020.07.003]
Aparicio J, García Del Muro X, Maroto P, Terrasa J, Castellano D, Bastús R, Gumà J, Sagastibeltza N, Durán I, Ochenduszko S, Meana JA, García-Sánchez J, Arranz JA, Gironés R, Germà JR (2021).

Patterns of relapse and treatment outcome after active surveillance or adjuvant carboplatin for stage I seminoma: a retrospective study of the Spanish Germ Cell Cancer Group

CLINICAL & TRANSLATIONAL ONCOLOGY. Article. 23(1):58-64.
[doi:10.1007/s12094-020-02393-9]
Lorz, C, Oteo, M, Santos, M (2021).

Neuroendocrine Lung Cancer Mouse Models: An Overview

Cancers. Review. 13(1).
[doi:10.3390/cancers13010014]

2020

Powles, T, van der Heijden, MS, Castellano, D, Galsky, MD, Loriot, Y, Petrylak, DP, Ogawa, O, Park, SN, Lee, JL, De Giorgi, U, Bögemann M, Bamias, A, Eigl, BJ, Gurney, H, Mukherjee, SD, Fradet, Y, Skoneczna, I, Tsiatas, M, Novikov, A, Suarez, C, Fay, AP, Duran, I, Necchi, A, Wildsmith, S, He, P, Angra, N, Gupta, AK, Levin, W, Bellmunt, J, DANUBE Study Investigators (2020).

Durvalumab alone and durvalumab plus tremelimumab versus chemotherapy in previously untreated patients with unresectable, locally advanced or metastatic urothelial carcinoma (DANUBE): a randomised, open-label, multicentre, phase 3 trial.

LANCET ONCOLOGY. Article. 21(12):1574-1588.
[doi:10.1016/S1470-2045(20)30541-6]
Bellmunt Molins J, García-Donas Jiménez J, Valderrama, BP, Virizuela Echaburu JA, Hernando-Polo, S, Climent Durán MÁ, Villa-Guzman, JC, Arranz Arija JÁ, Ostiategui, ML, Milagro, NL, Gonzalez-del-Alba, A, Gonzalez, BM, Diaz, EG, Gauna, DC, Santasusana, MD, Herranz, UA, Del Muro Solans XG, Perez-Gracia, JL, Vazquez, JP, Morales-Barrera, R, Pous, AF (2020).

Final Overall Survival Analysis of the SOGUG Phase 2 MAJA Study: Maintenance Vinflunine Versus Best Supportive Care After First-Line Chemotherapy in Advanced Urothelial Carcinoma.

CLINICAL GENITOURINARY CANCER. Article. 18(6):452-460.
[doi:10.1016/j.clgc.2020.05.004]
Gonzalez-Diaz, A, Abad-Lopez, P, Peña-Vallejo E, Caro-Gonzalez, MP, Calzas-Montalvo, C, Gil-Moradillo, J, Miranda-Utrera, N, Diez-Sebastian, J, Varela-Rodriguez, C, Rodriguez-Antolin, A, Tejido-Sanchez, A (2020).

Urological surgery during SARS-CoV-2 pandemic. Descriptive analysis of the experience in a Urology Department across the pandemic phases.

ACTAS UROLOGICAS ESPANOLAS. Article. 44(10):665-673.
[doi:10.1016/j.acuro.2020.09.007]
Roldan-Romero, JM, Santos, M, Lanillos, J, Caleiras, E, Anguera, G, Maroto, P, Garcia-Donas, J, de Velasco, G, Martinez-Montes, AM, Calsina, B, Monteagudo, M, Leton, R, Leandro-Garcia, LJ, Montero-Conde, C, Cascon, A, Robledo, M, Rodriguez-Antona, C (2020).

Molecular characterization of chromophobe renal cell carcinoma reveals mTOR pathway alterations in patients with poor outcome.

MODERN PATHOLOGY. Article. 33(12):2580-2590.
[doi:10.1038/s41379-020-0607-z]
Guerrero-Ramos F, Rodríguez-Antolín A (2020).

Nuevos quimioterápicos endovesicales y vehículos de aplicación: EMDA, Synergo, HIVEC y Unithermia.

ARCHIVOS ESPANOLES DE UROLOGIA. Article. 73(10):934-944.
de Velasco G, Carril-Ajuria L, Guerrero-Ramos F, Alonso-Gordoa T, Rodríguez-Moreno JF, Carretero A, Martin-Soberon M, de la Rosa-Kehrmann F, Castellano D (2020).

A case series of advanced renal cell carcinoma patients treated with neoadjuvant cabozantinib prior to cytoreductive nephrectomy within the phase 2 CABOPRE trial.

Oncotarget. Case Reports. 11(47):4457-4462.
[doi:10.18632/oncotarget.27807]
Carretero-Gonzalez, A, Lora, D, Manneh, R, Lorente, D, Castellano, D, de Velasco, G (2020).

Combination of statin/vitamin D and metastatic castration-resistant prostate cancer (CRPC): a post hoc analysis of two randomized clinical trials.

CLINICAL & TRANSLATIONAL ONCOLOGY. Article. 22(11):2126-2129.
[doi:10.1007/s12094-020-02334-6]
Sanchez-Pina, JM, Rodriguez, MR, Castro Quismondo N, Gil Manso R, Colmenares, R, Gil Alos D, Paciello, ML, Zafra, D, Garcia-Sanchez, C, Villegas, C, Cuellar, C, Carreño-Tarragona G, Zamanillo, I, Poza, M, Iñiguez R, Gutierrez, X, Alonso, R, Rodriguez, A, Folgueira, MD, Delgado, R, Ferrari, JM, Lizasoain, M, Aguado, JM, Ayala, R, Martinez-Lopez, J, Calbacho, M (2020).

Clinical course and risk factors for mortality from COVID-19 in patients with haematological malignancies.

EUROPEAN JOURNAL OF HAEMATOLOGY. Article. 105(5):597-607.
[doi:10.1111/ejh.13493]
Gómez Del Cañizo C, Rodríguez-Izquierdo Jiménez M, Peña Vallejo E, Duarte Ojeda JM, de la Rosa Kehrman F, Rodríguez Antolín A, Guerrero Ramos F (2020).

New immunotherapies for high-risk non-muscle invasive bladder cancer: Current state and future perspectives.

ACTAS UROLOGICAS ESPANOLAS. Review. 44(9):574-585.
[doi:10.1016/j.acuro.2020.06.011]
Tejido-Sanchez, A, Gonzalez-Diaz, A, Garcia-Rojo, E, Santos-Pérez de la Blanca R, Varela-Rodriguez, C, Ruiz-Lopez, P, Rodriguez-Antolin, A (2020).

Design of an assistance protocol for the restart of scheduled urologic surgery in a COVID-19 epidemic period.

ACTAS UROLOGICAS ESPANOLAS. Article. 44(9):597-603.
[doi:10.1016/j.acuro.2020.05.006]
Albiges L, Tannir N, Burotto M, Mcdermott D, Plimack E, Barthélémy P, Porta C, Powles T, Donskov F, George S, Kollmannsberger C, Gurney H, Grimm M, Tomita Y, Castellano D, Rini B, Choueiri T, Shally Saggi S, Mchenry M, Motzer R (2020).

Nivolumab + ipilimumab (N+I) vs sunitinib (S) dans le traitement de première ligne du carcinome rénal avancé (aRCC) dans l’étude CheckMate 214 : suivi à 4 ans et analyse en sous-groupe des patients (pts) non néphrectomisés.

PROGRES EN UROLOGIE. Article. 30(13):785-786.
[doi:10.1016/j.purol.2020.07.155]
Albiges, L, Tannir, NM, Burotto, M, McDermott, D, Plimack, ER, Barthelemy, P, Porta, C, Powles, T, Donskov, F, George, S, Kollmannsberger, CK, Gurney, H, Grimm, MO, Tomita, Y, Castellano, D, Rini, BI, Choueiri, TK, Saggi, SS, McHenry, MB, Motzer, RJ (2020).

Nivolumab plus ipilimumab versus sunitinib for first-line treatment of advanced renal cell carcinoma: extended 4-year follow-up of the phase III CheckMate 214 trial.

Esmo Open. Article. 5(6).
[doi:10.1136/esmoopen-2020-001079]
Rodriguez-Vida, A, Bamias, A, Esteban, E, Saez, MI, Lopez-Brea, M, Castellano, D, Caballero, C, Gonzalez-Larriba, JL, Calvo, E, Macia, S, Ravaud, A, Bellmunt, J (2020).

Randomised Phase II study comparing alternating cycles of sunitinib and everolimus vs standard sequential administration in first-line metastatic renal carcinoma (SUNRISES study).

BJU INTERNATIONAL. Article. 126(5):559-567.
[doi:10.1111/bju.15165]
Fizazi, K, Kramer, G, Eymard, JC, Sternberg, CN, de Bono, J, Castellano, D, Tombal, B, Whulfing, C, Liontos, M, Carles, J, Iacovelli, R, Melichar, B, Sverrisdottir, A, Theodore, C, Feyerabend, S, Helissey, C, Oudard, S, Facchini, G, Poole, EM, Ozatilgan, A, Geffriaud-Ricouard, C, Bensfia, S, de Wit, R (2020).

Quality of life in patients with metastatic prostate cancer following treatment with cabazitaxel versus abiraterone or enzalutamide (CARD): an analysis of a randomised, multicentre, open-label, phase 4 study

LANCET ONCOLOGY. Article. 21(11):1513-1525.
[doi:10.1016/S1470-2045(20)30449-6]
Santos Perez De La Blanca R, de la Rosa Kehrman F, Medina Polo J, Pamplona Casamayor M, Duarte Ojeda J, Tejido Sanchez A, Rodriguez Antolín A (2020).

La transplantation rénale itérative : notre expérience sur la troisième transplantation rénale.

PROGRES EN UROLOGIE. Article. 30(13):722-722.
[doi:10.1016/j.purol.2020.07.051]
Mapelli, SN, Albino, D, Mello-Grand, M, Shinde, D, Scimeca, M, Bonfiglio, R, Bonanno, E, Chiorino, G, Garcia-Escudero, R, Catapano, CV, Carbone, GM (2020).

Erratum: Mapelli, S.N., et al. A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors). Cancers 2020, 12, 176.

Cancers. Correction. 12(10).
[doi:10.3390/cancers12102971]
Iacovelli, R, Ciccarese, C, Schutz, FA, Tortora, G, de Velasco, G (2020).

Complete response to immune checkpoint inhibitors-based therapy in advanced renal cell carcinoma patients. A meta-analysis of randomized clinical trials.

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS. Article. 38(10).
[doi:10.1016/j.urolonc.2020.06.021]
Loriot, Y, Sternberg, CN, Castellano, D, Oosting, SF, Dumez, H, Huddart, R, Vianna, K, Alonso Gordoa T, Skoneczna, I, Fay, AP, Nole, F, Massari, F, Brasiuniene, B, Maroto, P, Fear, S, Di Nucci, F, de Ducla, S, Choy, E (2020).

Safety and efficacy of atezolizumab in patients with autoimmune disease: Subgroup analysis of the SAUL study in locally advanced/metastatic urinary tract carcinoma.

EUROPEAN JOURNAL OF CANCER. Article. 138:202-211.
[doi:10.1016/j.ejca.2020.07.023]
Carvalho, S, Abreu, CM, Ferreira, D, Lima, L, Ferreira, JA, Santos, LL, Ribeiro, R, Grenha, V, Martinez-Fernandez, M, Duenas, M, Suarez-Cabrera, C, Paramio, JM, Dieguez, L, Freitas, PP, Oliveira, MI (2020).

Phenotypic Analysis of Urothelial Exfoliated Cells in Bladder Cancer via Microfluidic Immunoassays: Sialyl-Tn as a Novel Biomarker in Liquid Biopsies.

Frontiers in oncology. Article. 10:1774-1774.
[doi:10.3389/fonc.2020.01774]
Motzer, RJ, Escudier, B, George, S, Hammers, HJ, Srinivas, S, Tykodi, SS, Sosman, JA, Plimack, ER, Procopio, G, McDermott, DF, Castellano, D, Choueiri, TK, Donskov, F, Gurney, H, Oudard, S, Richardet, M, Peltola, K, Alva, AS, Carducci, M, Wagstaff, J, Chevreau, C, Fukasawa, S, Tomita, Y, Gauler, TC, Kollmannsberger, CK, Schutz, FA, Larkin, J, Cella, D, McHenry, MB, Saggi, SS, Tannir, NM (2020).

Nivolumab versus everolimus in patients with advanced renal cell carcinoma: Updated results with long-term follow-up of the randomized, open-label, phase 3 CheckMate 025 trial.

CANCER. Article. 126(18):4156-4167.
[doi:10.1002/cncr.33033]
Alcaraz, A, Rodriguez-Antolin, A, Carballido-Rodriguez, J, Castro-Diaz, D, Esteban-Fuertes, M, Cozar-Olmo, JM, Ficarra, V, Medina-Lopez, R, Fernandez-Gomez, JM, Angulo, JC, Medina-Polo, J, Brenes-Bermudez, FJ, Molero-Garcia, JM, Fernandez-Pro-Ledesma, A, Manasanch, J, The Qualiprost Study Group OBO (2020).

Clinical Benefit of Tamsulosin and the Hexanic Extract of Serenoa Repens, in Combination or as Monotherapy, in Patients with Moderate/Severe LUTS-BPH: A Subset Analysis of the QUALIPROST Study.

Journal of Clinical Medicine. Article. 9(9).
[doi:10.3390/jcm9092909]
Castellano, D, Pablo Maroto J, Benzaghou, F, Taguieva, N, Nguyen, L, Clary, DO, Jonasch, E (2020).

Exposure-response modeling of cabozantinib in patients with renal cell carcinoma: Implications for patient care.

CANCER TREATMENT REVIEWS. Review. 89:102062-102062.
[doi:10.1016/j.ctrv.2020.102062]
Huddart RA, Siefker-Radtke AO, Balar AV, Bilen MA, Powles T, Bamias A, Castellano D, Khalil MF, Van Der Heijden MS, Koshkin VS, Pook DW, Özgüroglu M, Santiago L, Zhong B, Chien D, Lin W, Tagliaferri MA, Loriot Y (2020).

PIVOT-10: Phase II study of bempegaldesleukin plus nivolumab in cisplatin-ineligible advanced urothelial cancer

FUTURE ONCOLOGY. Article. 17(2):137-149.
[doi:10.2217/fon-2020-0795]
Carril-Ajuria, L, Remolina-Bonilla, YA, Carretero-Gonzalez, A, Martin-Soberon, M, Castellano, D, Bourlon, C, de Velasco, G, Bourlon, MT (2020).

Challenges of Treating a Patient With Advanced Prostate Cancer During the COVID-19 Pandemic.

ONCOLOGY-NEW YORK. Article. 34(8):317-319.
[doi:10.46883/ONC.2020.3408.0317]
Vuky, J, Balar, AV, Castellano, D, O'Donnell, PH, Grivas, P, Bellmunt, J, Powles, T, Bajorin, D, Hahn, NM, Savage, MJ, Fang, X, Godwin, JL, Frenkl, TL, Homet Moreno B, de Wit, R, Plimack, ER (2020).

Long-Term Outcomes in KEYNOTE-052: Phase II Study Investigating First-Line Pembrolizumab in Cisplatin-Ineligible Patients With Locally Advanced or Metastatic Urothelial Cancer.

JOURNAL OF CLINICAL ONCOLOGY. Article. 38(23):2658-2666.
[doi:10.1200/JCO.19.01213]
Nunes, SP, Henrique, R, Jeronimo, C, Paramio, JM (2020).

DNA Methylation as a Therapeutic Target for Bladder Cancer.

Cells. Review. 9(8).
[doi:10.3390/cells9081850]
Wells, JC, Graham, J, Beuselinck, B, Bjarnason, GA, Donskov, F, Hansen, AR, McKay, RR, Vaishampayan, U, De Velasco, G, Duh, MS, Huynh, L, Nguyen, C, Zanotti, G, Ramaswamy, K, Choueiri, TK, Heng DYC (2020).

Clinical Outcomes of First-line Sunitinib Followed by Immuno-oncology Checkpoint Inhibitors in Patients With Metastatic Renal Cell Carcinoma.

CLINICAL GENITOURINARY CANCER. Article. 18(4):350-359.
[doi:10.1016/j.clgc.2019.12.007]
Urun, Y, Hussain, SA, Bakouny, Z, Castellano, D, Kiliçkap S, Morgan, G, Mckay, RR, Pels, K, Schmidt, A, Doroshow, DB, Schutz, F, Albiges, L, Lopes, G, Catto JWF, Peters, S, Choueiri, TK (2020).

Survey of the Impact of COVID-19 on Oncologists' Decision Making in Cancer.

Jco Global Oncology. Article. 6:1248-1257.
[doi:10.1200/GO.20.00300]
Innes, AJ, Sun, B, Wagner, V, Brookes, S, McHugh, D, Pombo, J, Porreca, RM, Dharmalingam, G, Vernia, S, Zuber, J, Vannier, JB, Garcia-Escudero, R, Gil, J (2020).

XPO7 is a tumor suppressor regulating p21(CIP1)-dependent senescence

GENES & DEVELOPMENT. Article. 34(15-16):379-391.
[doi:10.1101/gad.343269.120]
Carretero-Gonzalez, A, Lora, D, Martín Sobrino I, Sáez Sanz I, Bourlon, MT, Anido Herranz U, Martínez Chanzá N, Castellano, D, de Velasco, G (2020).

The Value of PD-L1 Expression as Predictive Biomarker in Metastatic Renal Cell Carcinoma Patients: A Meta-Analysis of Randomized Clinical Trials.

Cancers. Review. 12(7).
[doi:10.3390/cancers12071945]
Subiela, JD, Rodriguez Faba O, Guerrero Ramos F, Vila Reyes H, Pisano, F, Breda, A, Palou, J (2020).

Carcinoma In Situ of the Urinary Bladder: A Systematic Review of Current Knowledge Regarding Detection, Treatment, and Outcomes.

European Urology Focus. Review. 6(4):674-682.
[doi:10.1016/j.euf.2019.03.012]
Font, A, Domènech M, Benitez, R, Rava, M, Marques, M, Ramirez, JL, Pineda, S, Dominguez-Rodriguez, S, Gago, JL, Badal, J, Carrato, C, Lopez, H, Quer, A, Castellano, D, Malats, N, Real, FX (2020).

Immunohistochemistry-Based Taxonomical Classification of Bladder Cancer Predicts Response to Neoadjuvant Chemotherapy.

Cancers. Article. 12(7).
[doi:10.3390/cancers12071784]
Romero-Otero, J, Garcia-Gomez, B, Garcia-Gonzalez, L, Garcia-Rojo, E, Abad-Lopez, P, Justo-Quintas, J, Duarte-Ojeda, J, Rodriguez-Antolin, A (2020).

Critical analysis of a multicentric experience with holmium laser enucleation of the prostate for benign prostatic hyperplasia: outcomes and complications of 10 years of routine clinical practice.

BJU INTERNATIONAL. Article. 126(1):177-182.
[doi:10.1111/bju.15028]
Witjes, JA, Babjuk, M, Bellmunt, J, Bruins, HM, De Reijke, TM, De Santis, M, Gillessen, S, James, N, Maclennan, S, Palou, J, Powles, T, Ribal, MJ, Shariat, SF, Van der Kwast, T, Xylinas, E, Agarwal, N, Arends, T, Bamias, A, Birtle, A, Black, PC, Bochner, BH, Bolla, M, Boormans, JL, Bossi, A, Briganti, A, Brummelhuis, I, Burger, M, Castellano, D, Cathomas, R, Chiti, A, Choudhury, A, Comperat, E, Crabb, S, Culine, S, De Bari, B, De Blok, W, De Visschere, PJL, Decaestecker, K, Dimitropoulos, K, Dominguez-Escrig, JL, Fanti, S, Fonteyne, V, Frydenberg, M, Futterer, JJ, Gakis, G, Geavlete, B, Gontero, P, Grubmuller, B, Hafeez, S, Hansel, DE, Hartmann, A, Hayne, D, Henry, AM, Hernandez, V, Herr, H, Herrmann, K, Hoskin, P, Huguet, J, Jereczek-Fossa, BA, Jones, R, Kamat, AM, Khoo, V, Kiltie, AE, Krege, S, Ladoire, S, Lara, PC, Leliveld, A, Linares-Espinos, E, Logager, V, Lorch, A, Loriot, Y, Meijer, R, Mir, MC, Moschini, M, Mostafid, H, Muller, AC, Muller, CR, N'Dow, J, Necchi, A, Neuzillet, Y, Oddens, JR, Oldenburg, J, Osanto, S, Oyen, WJG, Pacheco-Figueiredo, L, Pappot, H, Patel, MI, Pieters, BR, Plass, K, Remzi, M, Retz, M, Richenberg, J, Rink, M, Roghmann, F, Rosenberg, JE, Roupret, M, Rouviere, O, Salembier, C, Salminen, A, Sargos, P, Sengupta, S, Sherif, A, Smeenk, RJ, Smits, A, Stenzl, A, Thalmann, GN, Tombal, B, Turkbey, B, Lauridsen, SV, Valdagni, R, Van Der Heijden, AG, Van Poppel, H, Vartolomei, MD, Veskimae, E, Vilaseca, A, Rivera, FAV, Wiegel, T, Wiklund, P, Willemse, PPM, Williams, A, Zigeuner, R, Horwich, A (2020).

EAU-ESMO Consensus Statements on the Management of Advanced and Variant Bladder Cancer-An International Collaborative Multistakeholder Effort Under the Auspices of the EAU-ESMO Guidelines Committees (vol 77, pg 223, 2020)

EUROPEAN UROLOGY. Correction. 78(1):48-50.
[doi:10.1016/j.eururo.2020.03.017]
Hernandez, IH, Cabrera, JR, Santos-Galindo, M, Sanchez-Martin, M, Dominguez, V, Garcia-Escudero, R, Perez-Alvarez, MJ, Pintado, B, Lucas, JJ (2020).

Pathogenic SREK1 decrease in Huntington's disease lowers TAF1 mimicking X-linked dystonia parkinsonism.

BRAIN. Article. 143(7):2207-2219.
[doi:10.1093/brain/awaa150]
Palacios-Garcia, J, Sanz-Flores, M, Asensio, A, Alvarado, R, Rojo-Berciano, S, Stamatakis, K, Paramio, JM, Cano, A, Nieto, MA, Garcia-Escudero, R, Mayor, F, Ribas, C (2020).

G-protein coupled receptor kinase 2 safeguards epithelial phenotype in Head and Neck Squamous Cell Carcinomas.

INTERNATIONAL JOURNAL OF CANCER. Article. 147(1):218-229.
[doi:10.1002/ijc.32838]
Kuderer, NM, Choueiri, TK, Shah, DP, Shyr, Y, Rubinstein, SM, Rivera, DR, Shete, S, Hsu, CY, Desai, A, de Lima Lopes G, Grivas, P, Painter, CA, Peters, S, Thompson, MA, Bakouny, Z, Batist, G, Bekaii-Saab, T, Bilen, MA, Bouganim, N, Larroya, MB, Castellano, D, Del Prete, SA, Doroshow, DB, Egan, PC, Elkrief, A, Farmakiotis, D, Flora, D, Galsky, MD, Glover, MJ, Griffiths, EA, Gulati, AP, Gupta, S, Hafez, N, Halfdanarson, TR, Hawley, JE, Hsu, E, Kasi, A, Khaki, AR, Lemmon, CA, Lewis, C, Logan, B, Masters, T, McKay, RR, Mesa, RA, Morgans, AK, Mulcahy, MF, Panagiotou, OA, Peddi, P, Pennell, NA, Reynolds, K, Rosen, LR, Rosovsky, R, Salazar, M, Schmidt, A, Shah, SA, Shaya, JA, Steinharter, J, Stockerl-Goldstein, KE, Subbiah, S, Vinh, DC, Wehbe, FH, Weissmann, LB, Wu, JTY, Wulff-Burchfield, E, Xie, ZE, Yeh, A, Yu, PP, Zhou, AY, Zubiri, L, Mishra, S, Lyman, GH, Rini, BI, Warner, JL, COVID-19 Canc Consortium (2020).

Clinical impact of COVID-19 on patients with cancer (CCC19): a cohort study.

LANCET. Article. 395(10241):1907-1918.
[doi:10.1016/S0140-6736(20)31187-9]
Couñago F, Lopez-Campos, F, Diaz-Gavela, AA, Almagro, E, Fenandez-Pascual, E, Henriquez, I, Lozano, R, Linares Espinós E, Gomez-Iturriaga, A, de Velasco, G, Quintana Franco LM, Rodriguez-Melcon, I, Lopez-Torrecilla, J, Spratt, DE, Guerrero, LL, Martinez-Salamanca, JI, del Cerro, E (2020).

Clinical Applications of Molecular Biomarkers in Prostate Cancer.

Cancers. Review. 12(6).
[doi:10.3390/cancers12061550]
Hermanova, I, Zuniga-Garcia, P, Caro-Maldonado, A, Fernandez-Ruiz, S, Salvador, F, Martin-Martin, N, Zabala-Letona, A, Nunez-Olle, M, Torrano, V, Camacho, L, Lizcano, JM, Talamillo, A, Carreira, S, Gurel, B, Cortazar, AR, Guiu, M, Lopez, JI, Martinez-Romero, A, Astobiza, I, Valcarcel-Jimenez, L, Lorente, M, Arruabarrena-Aristorena, A, Velasco, G, Gomez-Munoz, A, Suarez-Cabrera, C, Lodewijk, I, Flores, JM, Sutherland, JD, Barrio, R, de Bono, JS, Paramio, JM, Trka, J, Graupera, M, Gomis, RR, Carracedo, A (2020).

Genetic manipulation of LKB1 elicits lethal metastatic prostate cancer.

JOURNAL OF EXPERIMENTAL MEDICINE. Article. 217(6).
[doi:10.1084/jem.20191787]
Medina-Polo, J, Téigell Tobar J, Romero-Otero, J, Carballido-Rodriguez, J, Dominguez-Esteban, M, Martinez-Berganza, ML, Miñana-López B, Unda Urzaiz JM, Rodriguez-Antolin, A (2020).

Manejo de la hiperplasia benigna de próstata durante la pandemia COVID-19.

ARCHIVOS ESPANOLES DE UROLOGIA. Article. 73(5):405-412.
Manso, L, De Velasco, G, Paz-Ares, L (2020).

Impact of the COVID-19 outbreak on cancer patient flow and management: experience from a large university hospital in Spain.

Esmo Open. Letter. 4(Suppl 2).
[doi:10.1136/esmoopen-2020-000828]
Grivas, P, Plimack, ER, Balar, AV, Castellano, D, O'Donnell, PH, Bellmunt, J, Powles, T, Hahn, NM, de Wit, R, Bajorin, DF, Ellison, MC, Frenkl, TL, Godwin, JL, Vuky, J (2020).

Pembrolizumab as First-line Therapy in Cisplatin-ineligible Advanced Urothelial Cancer (KEYNOTE-052): Outcomes in Older Patients by Age and Performance Status.

European Urology Oncology. Article. 3(3):351-359.
[doi:10.1016/j.euo.2020.02.009]
Hevia, V, Linares-Espinos, E, Alonso-Gordoa, T, Fernandez-Pello, S, Guerrero-Ramos, F, Mir, C, Molina-Cerrillo, J, Musquera-Felip, M, Rodriguez-Faba, O, de Velasco, G, Gomez-Dos Santos, V (2020).

Renal cell carcinoma and COVID-19 pandemia: Management strategies adapted to current practice.

ARCHIVOS ESPANOLES DE UROLOGIA. Article. 73(5):360-366.
Powles, T, Kockx, M, Rodriguez-Vida, A, Duran, I, Crabb, SJ, Van Der Heijden, MS, Szabados, B, Pous, AF, Gravis, G, Herranz, UA, Protheroe, A, Ravaud, A, Maillet, D, Mendez, MJ, Suarez, C, Linch, M, Prendergast, A, van Dam, PJ, Stanoeva, D, Daelemans, S, Mariathasan, S, Tea, JS, Mousa, K, Banchereau, R, Castellano, D (2020).

Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial (vol 25, pg 1706, 2019)

NATURE MEDICINE. Correction. 26(6):983-983.
[doi:10.1038/s41591-020-0923-3]
Subiela, JD, Rodriguez Faba, O, Guerrero-Ramos, F, Aumatell, J, Breda, A, Palou, J (2020).

Carcinoma in situ of the bladder: why is it underdetected?

CURRENT OPINION IN UROLOGY. Review. 30(3):392-399.
[doi:10.1097/MOU.0000000000000758]
Gil-Gil, T, Corona, F, Martinez, JL, Bernardini, A (2020).

The Inactivation of Enzymes Belonging to the Central Carbon Metabolism Is a Novel Mechanism of Developing Antibiotic Resistance

mSystems. Article. 5(3).
[doi:10.1128/mSystems.00282-20]
Jimenez-Segovia, A, Mota, A, Rojo-Sebastian, A, Barrocal, B, Rynne-Vidal, A, Garcia-Bermejo, ML, Gomez-Bris, R, Hawinkels, LJAC, Sandoval, P, Garcia-Escudero, R, Lopez-Cabrera, M, Moreno-Bueno, G, Fresno, M, Stamatakis, K (2020).

"Prostaglandin F-2 alpha-induced prostate transmembrane protein, androgen induced 1 mediate ovarian cancer progression increasing epithelial plasticity" (vol 21, pg 1073, 2019)

NEOPLASIA. Correction. 22(5):217-219.
[doi:10.1016/j.neo.2020.03.003]
Cabrera, J, Fernandez-Ruiz, M, Trujillo, H, Gonzalez, E, Molina, M, Polanco, N, Hernandez, E, Morales, E, Gutierrez, E, Rodríguez Mori J, Canon, A, Rodríguez-Antolín A, Praga, M, Andres, A (2020).

Kidney transplantation in the extremely elderly from extremely aged deceased donors: a kidney for each age.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 35(4):687-696.
[doi:10.1093/ndt/gfz293]
Matsubara, N, Chi, KN, Ozguroglu, M, Rodriguez-Antolin, A, Feyerabend, S, Fein, L, Alekseev, BY, Sulur, G, Protheroe, A, Li, SS, Mundle, S, De Porre, P, Tran, N, Fizazi, K (2020).

Correlation of Prostate-specific Antigen Kinetics with Overall Survival and Radiological Progression-free Survival in Metastatic Castration-sensitive Prostate Cancer Treated with Abiraterone Acetate plus Prednisone or Placebos Added to Androgen Deprivation Therapy: Post Hoc Analysis of Phase 3 LATITUDE Study

EUROPEAN UROLOGY. Article. 77(4):494-500.
[doi:10.1016/j.eururo.2019.11.021]
Garcia-Rodriguez J, Fernandez-Gomez JM, Cozar JM, Minana B, Gomez-Veiga F, Rodriguez-Antolin A, en representación del Grupo Español de Cáncer de Próstata (GESCAP), En representación del del Grupo Español de Cáncer de Próstata (GESCAP) (2020).

Androgen deprivation therapy in patients with localized disease: Comparison with curative intent treatments and time to castration resistance. Results of the Spanish Prostate Cancer Registry.

ACTAS UROLOGICAS ESPANOLAS. Article. 44(3):156-163.
[doi:10.1016/j.acuro.2019.06.006]
de Wit, R, de Bono, J, Castellano, D (2020).

Cabazitaxel in Metastatic Prostate Cancer

NEW ENGLAND JOURNAL OF MEDICINE. Letter. 382(13):1286-1286.
Roldan-Romero JM, Beuselinck B, Santos M, Rodriguez-Moreno JF, Lanillos J, Calsina B, Gutierrez A, Tang K, Lainez N, Puente J, Castellano D, Esteban E, Climent MA, Arranz JA, Albersen M, Oudard S, Couchy G, Caleiras E, Montero-Conde C, Cascón A, Robledo M, Rodríguez-Antona C, García-Donas J, Spanish Oncology Genitourinary Group (SOGUG) (2020).

PTEN expression and mutations in TSC1, TSC2 and MTOR are associated with response to rapalogs in patients with renal cell carcinoma.

INTERNATIONAL JOURNAL OF CANCER. Article. 146(5):1435-1444.
[doi:10.1002/ijc.32579]
Lazaro, M, Valderrama, BP, Suarez, C, de-Velasco, G, Beato, C, Chirivella, I, Gonzalez-Del-Alba, A, Lainez, N, Mendez-Vidal, MJ, Arranz, JA (2020).

SEOM clinical guideline for treatment of kidney cancer (2019).

CLINICAL & TRANSLATIONAL ONCOLOGY. Article. 22(2):256-269.
[doi:10.1007/s12094-019-02285-7]
Gómez de Liaño Lista A, van Dijk, N, de Velasco Oria de Rueda G, Necchi, A, Lavaud, P, Morales-Barrera, R, Alonso Gordoa T, Maroto, P, Ravaud, A, Duran, I, Szabados, B, Castellano, D, Giannatempo, P, Loriot, Y, Carles, J, Anguera Palacios G, Lefort, F, Raggi, D, Gross Goupil M, Powles, T, Van der Heijden, MS (2020).

Clinical outcome after progressing to frontline and second-line Anti-PD-1/PD-L1 in advanced urothelial cancer.

EUROPEAN UROLOGY. Article. 77(2):269-276.
[doi:10.1016/j.eururo.2019.10.004]
Witjes, JA, Babjuk, M, Bellmunt, J, Bruins, HM, De Reijke, TM, De Santis, M, Gillessen, S, James, N, Maclennan, S, Palou, J, Powles, T, Ribal, MJ, Shariat, SF, Van der Kwast, T, Xylinas, E, Agarwal, N, Arends, T, Bamias, A, Birtle, A, Black, PC, Bochner, BH, Bolla, M, Boormans, JL, Bossi, A, Briganti, A, Brummelhuis, I, Burger, M, Castellano, D, Cathomas, R, Chiti, A, Choudhury, A, Comperat, E, Crabb, S, Culine, S, De Bari, B, De Blok, W, De Visschere, PJL, Decaestecker, K, Dimitropoulos, K, Dominguez-Escrig, JL, Fanti, S, Fonteyne, V, Frydenberg, M, Futterer, JJ, Gakis, G, Geavlete, B, Gontero, P, Grubmuller, B, Hafeez, S, Hansel, DE, Hartmann, A, Hayne, D, Henry, AM, Hernandez, V, Herr, H, Herrmann, K, Hoskin, P, Huguet, J, Jereczek-Fossa, BA, Jones, R, Kamat, AM, Khoo, V, Kiltie, AE, Krege, S, Ladoire, S, Lara, PC, Leliveld, A, Linares-Espinos, E, Logager, V, Lorch, A, Loriot, Y, Meijer, R, Mir, MC, Moschini, M, Mostafid, H, Muller, AC, Muller, CR, N'Dow, J, Necchi, A, Neuzillet, Y, Oddens, JR, Oldenburg, J, Osanto, S, Oyen, WJG, Pacheco-Figueiredo, L, Pappot, H, Patel, MI, Pieters, BR, Plass, K, Remzi, M, Retz, M, Richenberg, J, Rink, M, Roghmann, F, Rosenberg, JE, Roupret, M, Rouviere, O, Salembier, C, Salminen, A, Sargos, P, Sengupta, S, Sherif, A, Smeenk, RJ, Smits, A, Stenzl, A, Thalmann, GN, Tombal, B, Turkbey, B, Lauridsen, SV, Valdagni, R, Van der Heijden, AG, Van Poppel, H, Vartolomei, MD, Veskimae, E, Vilaseca, A, Rivera, FAV, Wiegel, T, Wiklund, P, Williams, A, Zigeuner, R, Horwich, A (2020).

EAU-ESMO Consensus Statements on the Management of Advanced and Variant Bladder Cancer-An International Collaborative Multistakeholder Effort Under the Auspices of the EAU-ESMO Guidelines Committees

EUROPEAN UROLOGY. Article. 77(2):223-250.
[doi:10.1016/j.eururo.2019.09.035]
Gargini, R, Segura-Collar, B, Herranz, B, Garcia-Escudero, V, Romero-Bravo, A, Nunez, FJ, Garcia-Perez, D, Gutierrez-Guaman, J, Ayuso-Sacido, A, Seoane, J, Perez-Nunez, A, Sepulveda-Sanchez, JM, Hernandez-Lain, A, Castro, MG, Garcia-Escudero, R, Avila, J, Sanchez-Gomez, P (2020).

The IDH-TAU-EGFR triad defines the neovascular landscape of diffuse gliomas.

SCIENCE TRANSLATIONAL MEDICINE. Article. 12(527).
[doi:10.1126/scitranslmed.aax1501]
de Velasco, G (2020).

Optimising first-line treatment for metastatic renal cell carcinoma.

LANCET. Letter. 395(10219):7-7.
[doi:10.1016/S0140-6736(19)32495-X]
Mapelli, SN, Albino, D, Mello-Grand, M, Shinde, D, Scimeca, M, Bonfiglio, R, Bonanno, E, Chiorino, G, Garcia-Escudero, R, Catapano, CV, Carbone, GM (2020).

A Novel Prostate Cell Type-Specific Gene Signature to Interrogate Prostate Tumor Differentiation Status and Monitor Therapeutic Response (Running Title: Phenotypic Classification of Prostate Tumors).

Cancers. Article. 12(1).
[doi:10.3390/cancers12010176]
Page, A, Bravo, A, Suarez-Cabrera, C, Sanchez-Baltasar, R, Oteo, M, Morcillo, MA, Casanova, ML, Segovia, JC, Navarro, M, Ramirez, A (2020).

IKKß overexpression together with a lack of tumour suppressor genes causes ameloblastic odontomas in mice.

INTERNATIONAL JOURNAL OF ORAL SCIENCE. Article. 12(1):1-1.
[doi:10.1038/s41368-019-0067-9]
Petrylak, DP, de Wit, R, Chi, KN, Drakaki, A, Sternberg, CN, Nishiyama, H, Castellano, D, Hussain, SA, Flechon, A, Bamias, A, Yu, EY, van der Heijden, MS, Matsubara, N, Alekseev, B, Necchi, A, Geczi, L, Ou, YC, Coskun, HS, Su, WP, Bedke, J, Gakis, G, Percent, IJ, Lee, JL, Tucci, M, Semenov, A, Laestadius, F, Peer, A, Tortora, G, Safina, S, Garcia Del Muro X, Rodriguez-Vida, A, Cicin, I, Harputluoglu, H, Tagawa, ST, Vaishampayan, U, Aragon-Ching, JB, Hamid, O, Liepa, AM, Wijayawardana, S, Russo, F, Walgren, RA, Zimmermann, AH, Hozak, RR, Bell-McGuinn, KM, Powles, T, RANGE Study Investigators (2020).

Ramucirumab plus docetaxel versus placebo plus docetaxel in patients with locally advanced or metastatic urothelial carcinoma after platinum-based therapy (RANGE): overall survival and updated results of a randomised, double-blind, phase 3 trial.

LANCET ONCOLOGY. Article. 21(1):105-120.
[doi:10.1016/S1470-2045(19)30668-0]
Tran, B, Ruiz-Morales, JM, Gonzalez-Billalabeitia, E, Patrikidou, A, Amir, E, Seidel, C, Bokemeyer, C, Fankhauser, C, Hermanns, T, Rumyantsev, A, Tryakin, A, Brito, M, Flechon, A, Kwan, EM, Cheng, T, Castellano, D, Garcia Del Muro X, Hamid, AA, Ottaviano, M, Palmieri, G, Kitson, R, Reid, A, Heng DYC, Bedard, PL (2020).

Large retroperitoneal lymphadenopathy and increased risk of venous thromboembolism in patients receiving first-line chemotherapy for metastatic germ cell tumors: A study by the global germ cell cancer group (G3).

Cancer Medicine. Article. 9(1):116-124.
[doi:10.1002/cam4.2674]
Lopez-Mateo, I, Alonso-Merino, E, Suarez-Cabrera, C, Park, JW, Cheng, SY, Alemany, S, Paramio, JM, Aranda, A (2020).

Thyroid Hormone Receptor beta Inhibits Self-Renewal Capacity of Breast Cancer Stem Cells

Thyroid. Article. 30(1):116-132.
[doi:10.1089/thy.2019.0175]
Trilla-Fuertes, L, Miranda, N, Castellano, D, Lopez-Vacas, R, Farfán Tello CA, de Velasco, G, Villacampa, F, Lopez-Camacho, E, Prado-Vazquez, G, Zapater-Moros, A, Espinosa, E, Fresno Vara JÁ, Pinto, A, Gamez-Pozo, A (2020).

miRNA profiling in renal carcinoma suggest the existence of a group of pro-angionenic tumors in localized clear cell renal carcinoma.

PLOS ONE. Article. 15(2).
[doi:10.1371/journal.pone.0229075]
Drakaki, A, Kirby, CJ, Van der Heijden, MS, Petrylak, DP, Powles, T, Chi, KN, Flechon, A, Necchi, A, Geczi, L, Lee, JL, Gakis, G, Bracarda, S, Chowdhury, S, Lin, CC, Keizman, D, Vaishampayan, UN, Zimmermann, AH, Bell-McGuinn, K, Castellano, D (2020).

Docetaxel with or without Ramucirumab after Platinum-Based Chemotherapy and Checkpoint Inhibitors in Advanced Urothelial Carcinoma: A Pre-Specified Subgroup Analysis from the Phase 3 RANGE Trial

Bladder Cancer. Article. 6(1):43-52.
[doi:10.3233/BLC-190252]
Segrelles, C, Santos-de-Frutos, K, Paramio, JM, Lorz, C (2020).

Competitive Repopulation Assay of Long-Term Epidermal Stem Cell Regeneration Potential

Methods in Molecular Biology. Article. 2109:45-53.
[doi:10.1007/7651_2019_234]

2019

Wulfing, C, Sverrisdottir, A, de Wit, R, de Bono, J, Sternberg, CN, Fizazi, K, Tombal, B, Wulfing, C, Kramer, G, Eymard, JC, Bamias, A, Carles, J, Iacovelli, R, Melichar, B, Sverrisdottir, A, Theodore, C, Feyerabend, S, Helissey, C, Ozatilgan, A, Geffriaud-Ricouard, C, Castellano, D, CARD Investigators (2019).

Cabazitaxel versus Abiraterone or Enzalutamide in Metastatic Prostate Cancer

NEW ENGLAND JOURNAL OF MEDICINE. Article. 381(26):2506-2518.
[doi:10.1056/NEJMoa1911206]
Carril-Ajuria, L, Santos, M, Roldan-Romero, JM, Rodriguez-Antona, C, de Velasco, G (2019).

Prognostic and Predictive Value of PBRM1 in Clear Cell Renal Cell Carcinoma.

Cancers. Review. 12(1).
[doi:10.3390/cancers12010016]
Santos-de-Frutos K, Segrelles C, Lorz C (2019).

Hippo Pathway and YAP Signaling Alterations in Squamous Cancer of the Head and Neck.

Journal of Clinical Medicine. Review. 8(12).
[doi:10.3390/jcm8122131]
Dudani, S, Graham, J, Wells, JC, Bakouny, Z, Pal, SK, Dizman, N, Donskov, F, Porta, C, de Velasco, G, Hansen, A, Iafolla, M, Beuselinck, B, Vaishampayan, UN, Woodk, LA, Liow, E, Yan, F, Yuasa, T, Bjarnason, GA, Choueiri, TK, Heng DYC (2019).

First-line Immuno-Oncology Combination Therapies in Metastatic Renal-cell Carcinoma: Results from the International Metastatic Renal-cell Carcinoma Database Consortium.

EUROPEAN UROLOGY. Article. 76(6):861-867.
[doi:10.1016/j.eururo.2019.07.048]
Martinez, VG, Munera-Maravilla, E, Bernardini, A, Rubio, C, Suarez-Cabrera, C, Segovia, C, Lodewijk, I, Dueñas M, Martinez-Fernandez, M, Paramio, JM (2019).

Epigenetics of Bladder Cancer: Where Biomarkers and Therapeutic Targets Meet.

Frontiers in Genetics. Review. 10:1125-1125.
[doi:10.3389/fgene.2019.01125]
Carretero-Gonzalez, A, Salamanca Santamaría J, Castellano, D, de Velasco, G (2019).

Three case reports: Temporal association between tyrosine-kinase inhibitor-induced hepatitis and immune checkpoint inhibitors in renal cell carcinoma.

MEDICINE. Article. 98(47).
[doi:10.1097/MD.0000000000018098]
Jiménez-Segovia A, Mota, A, Rojo-Sebastin, A, Barrocal, B, Rynne-Vidal, A, García-Bermejo ML, Gómez-Bris R, Hawinkels LJAC, Sandoval, P, Garcia-Escudero, R, López-Cabrera M, Moreno-Bueno, G, Fresno, M, Stamatakis, K (2019).

Prostaglandin F 2a -induced Prostate Transmembrane Protein, Androgen Induced 1 mediates ovarian cancer progression increasing epithelial plasticity.

NEOPLASIA. Article. 21(11):1073-1084.
[doi:10.1016/j.neo.2019.10.001]
Powles, T, Kockx, M, Rodriguez-Vida, A, Duran, I, Crabb, SJ, Van der Heijden, MS, Szabados, B, Pous, AF, Gravis, G, Herranz, UA, Protheroe, A, Ravaud, A, Maillet, D, Mendez, MJ, Suarez, C, Linch, M, Prendergast, A, van Dam, PJ, Stanoeva, D, Daelemans, S, Mariathasan, S, Tea, JS, Mousa, K, Banchereau, R, Castellano, D (2019).

Clinical efficacy and biomarker analysis of neoadjuvant atezolizumab in operable urothelial carcinoma in the ABACUS trial.

NATURE MEDICINE. Article. 25(11):1706-1714.
[doi:10.1038/s41591-019-0628-7]
Horwich, A, Babjuk, M, Bellmunt, J, Bruins, HM, De Reijke, TM, De Santis, M, Gillessen, S, James, N, Maclennan, S, Palou, J, Powles, T, Ribal, MJ, Shariat, SF, Van der Kwast, T, Xylinas, E, Agarwal, N, Arends, T, Bamias, A, Birtle, A, Black, PC, Bochner, BH, Bolla, M, Boormans, JL, Bossi, A, Briganti, A, Brummelhuis, I, Burger, M, Castellano, D, Cathomas, R, Chiti, A, Choudhury, A, Comperat, E, Crabb, S, Culine, S, De Bari, B, De Blok, W, De Visschere, PJL, Decaestecker, K, Dimitropoulos, K, Dominguez-Escrig, JL, Fanti, S, Fonteyne, V, Frydenberg, M, Futterer, JJ, Gakis, G, Geavlete, B, Gontero, P, Grubmuller, B, Hafeez, S, Hansel, DE, Hartmann, A, Hayne, D, Henry, AM, Hernandez, V, Herr, H, Herrmann, K, Hoskin, P, Huguet, J, Jereczek-Fossa, BA, Jones, R, Kamat, AM, Khoo, V, Kiltie, AE, Krege, S, Ladoire, S, Lara, PC, Leliveld, A, Linares-Espinos, E, Logager, V, Lorch, A, Loriot, Y, Meijer, R, Mir, MC, Moschini, M, Mostafid, H, Muller, AC, Muller, CR, N'Dow, J, Necchi, A, Neuzillet, Y, Oddens, JR, Oldenburg, J, Osanto, S, Oyen, WJG, Pacheco-Figueiredo, L, Pappot, H, Patel, MI, Pieters, BR, Plass, K, Remzi, M, Retz, M, Richenberg, J, Rink, M, Roghmann, F, Rosenberg, JE, Roupret, M, Rouviere, O, Salembier, C, Salminen, A, Sargos, P, Sengupta, S, Sherif, A, Smeenk, RJ, Smits, A, Stenzl, A, Thalmann, GN, Tombal, B, Turkbey, B, Lauridsen, SV, Valdagni, R, Van der Heijden, AG, Van Poppel, H, Vartolomei, MD, Veskimae, E, Vilaseca, A, Rivera, FAV, Wiegel, T, Wiklund, P, Williams, A, Zigeuner, R, Witjes, JA (2019).

EAU-ESMO consensus statements on the management of advanced and variant bladder cancer-an international collaborative multi-stakeholder effort: under the auspices of the EAU and ESMO Guidelines Committees

ANNALS OF ONCOLOGY. Article. 30(11):1697-1727.
[doi:10.1093/annonc/mdz296]
García Rojo E, García Gómez B, González Padilla DA, Abad López P, García González L, Rodríguez Antolín A, Romero Otero J (2019).

Assessment of the influence of transrectal and transperineal prostate biopsies on erectile function: A prospective observational single-center study.

INTERNATIONAL JOURNAL OF UROLOGY. Article. 26(11):1054-1058.
[doi:10.1111/iju.14088]
Lazaro, S, Perez-Crespo, M, Lorz, C, Bernardini, A, Oteo, M, Enguita, AB, Romero, E, Hernandez, P, Tomas, L, Morcillo, MA, Paramio, JM, Santos, M (2019).

Differential development of large-cell neuroendocrine or small-cell lung carcinoma upon inactivation of 4 tumor suppressor genes.

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Article. 116(44):22300-22306.
[doi:10.1073/pnas.1821745116]
Rodríguez Antolín A, Martinez-Pineiro, L, Jiménez Romero ME, García Ramos JB, López Bellido D, Muñoz Del Toro J, Garcia-Porrero, AG, Gómez Veiga F (2019).

PREVALENCE OF FATIGUE AND IMPACT ON QUALITY OF LIFE IN CASTRATION-RESISTANT PROSTATE CANCER PATIENTS: the VITAL study.

BMC UROLOGY. Article. 19(1):92-92.
[doi:10.1186/s12894-019-0527-8]
Romero-Otero, J, Garcia-Gonzalez, L, Garcia-Gomez, B, Justo-Quintas, J, Garcia-Rojo, E, Gonzalez-Padilla, DA, Sopeña-Sutil R, Duarte-Ojeda, JM, Rodriguez-Antolin, A (2019).

Factors Influencing Intraoperative Blood Loss in Patients Undergoing Holmium Laser Enucleation of the Prostate (HoLEP) for Benign Prostatic Hyperplasia: A Large Multicenter Analysis.

UROLOGY. Article. 132:177-182.
[doi:10.1016/j.urology.2019.06.024]
García Rojo E, González Padilla DA, Castelo Loureiro A, Parrilla Rubio L, Tejido Sánchez Á, Guerrero Ramos F (2019).

New case of secondary bladder amyloidosis with massive hematuria-role of intravesical instillations with dimethyl sulfoxide.

Translational Andrology and Urology. Article. 8(5):548-555.
[doi:10.21037/tau.2019.09.22]
Manneh Kopp RA, Sepulveda-Sanchez, JM, Ruano, Y, Toldos, O, Perez Nunez A, Cantero, D, Hilario, A, Ramos, A, de Velasco, G, Sanchez-Gomez, P, Hernandez-Lain, A (2019).

Correlation of radiological and immunochemical parameters with clinical outcome in patients with recurrent glioblastoma treated with Bevacizumab.

CLINICAL & TRANSLATIONAL ONCOLOGY. Article. 21(10):1413-1423.
[doi:10.1007/s12094-019-02070-6]
de Velasco, G, Bex, A, Albiges, L, Powles, T, Rini, BI, Motzer, RJ, Heng DYC, Escudier, B (2019).

Sequencing and Combination of Systemic Therapy in Metastatic Renal Cell Carcinoma.

European Urology Oncology. Review. 2(5):505-514.
[doi:10.1016/j.euo.2019.06.022]
Auvray M, Auclin E, Barthelemy P, Bono P, Kellokumpu-Lehtinen P, Gross-Goupil M, De Velasco G, Powles T, Mouillet G, Vano YA, Gravis G, Mourey L, Priou F, Rolland F, Escudier B, Albiges L (2019).

Erratum to 'Second-line targeted therapies after nivolumab-ipilimumab failure in metastatic renal cell carcinoma' [Eur J Cancer 108 (February 2019) 33-40].

EUROPEAN JOURNAL OF CANCER. Correction. 119:200-201.
[doi:10.1016/j.ejca.2019.04.012]
Mapelli, SN, Napoli, S, Pisignano, G, Garcia-Escudero, R, Carbone, GM, Catapano, CV (2019).

Deciphering the complexity of human non-coding promoter-proximal transcriptome

Bioinformatics. Article. 35(15):2529-2534.
[doi:10.1093/bioinformatics/bty981]
Bamias, A, Hegele, A, Medioni, J, Castellano, D, Doni, L, Passalacqua, R, Zagouri, F, Tzannis, K, Hussain, S, Ullen, A (2019).

Vinflunine in the treatment of relapsed metastatic urothelial cancer: A systematic review and meta-analysis of real-world series

CRITICAL REVIEWS IN ONCOLOGY HEMATOLOGY. Review. 140:80-87.
[doi:10.1016/j.critrevonc.2019.05.006]
Dueñas M, Perez-Figueroa, A, Oliveira, C, Suarez-Cabrera, C, Sousa, A, Oliveira, P, Villacampa, F, Paramio, JM, Martinez-Fernandez, M (2019).

Gene Expression Analyses in Non Muscle Invasive Bladder Cancer Reveals a Role for Alternative Splicing and Tp53 Status.

SCIENTIFIC REPORTS. Article. 9(1):10362-10362.
[doi:10.1038/s41598-019-46652-4]
Romero-Otero, J, Garcia-Gonzalez L, Garcia-Gomez, B, Alonso-Isa, M, Garcia-Rojo, E, Gil-Moradillo, J, Duarte-Ojeda, JM, Rodriguez-Antolin, A (2019).

Analysis of holmium laser enucleation of the prostate in a high volume centre: the impact of concomitant holmium laser cystolitholapaxy.

JOURNAL OF ENDOUROLOGY. Article. 33(7):564-569.
[doi:10.1089/end.2019.0019]
Sternberg, CN, Loriot, Y, James, N, Choy, E, Castellano, D, Lopez-Rios, F, Banna, GL, De Giorgi, U, Masini, C, Bamias, A, Garcia Del Muro X, Duran, I, Powles, T, Gamulin, M, Zengerling, F, Geczi, L, Gedye, C, de Ducla, S, Fear, S, Merseburger, AS (2019).

Primary Results from SAUL, a Multinational Single-arm Safety Study of Atezolizumab Therapy for Locally Advanced or Metastatic Urothelial or Nonurothelial Carcinoma of the Urinary Tract.

EUROPEAN UROLOGY. Article. 76(1):73-81.
[doi:10.1016/j.eururo.2019.03.015]
Carretero Gonzalez A, Martin, MC, Luyo, M, Castellano, D, de Velasco, G (2019).

Challenges of treatment selection in the older prostate patient.

JOURNAL OF GERIATRIC ONCOLOGY. Letter. 10(4):666-668.
[doi:10.1016/j.jgo.2019.01.009]
Segovia, C, San Jose-Eneriz, E, Munera-Maravilla, E, Martinez-Fernandez, M, Garate, L, Miranda, E, Vilas-Zornoza, A, Lodewijk, I, Rubio, C, Segrelles, C, Valcarcel, LV, Rabal, O, Casares, N, Bernardini, A, Suarez-Cabrera, C, Lopez-Calderon, FF, Fortes, P, Casado, JA, Dueñas M, Villacampa, F, Lasarte, JJ, Guerrero-Ramos, F, de Velasco, G, Oyarzabal, J, Castellano, D, Agirre, X, Prosper, F, Paramio, JM (2019).

Inhibition of a G9a/DNMT network triggers immune-mediated bladder cancer regression.

NATURE MEDICINE. Article. 25(7):1073-1081.
[doi:10.1038/s41591-019-0499-y]
Loras, A, Suarez-Cabrera, C, Martinez-Bisbal, MC, Quintas, G, Paramio, JM, Martinez-Manez, R, Gil, S, Ruiz-Cerdia, JL (2019).

Integrative Metabolomic and Transcriptomic Analysis for the Study of Bladder Cancer.

Cancers. Article. 11(5).
[doi:10.3390/cancers11050686]
Carretero-González A, Lora D, Ghanem I, Otero I, López F, Castellano D, de Velasco G (2019).

Comparative safety analysis of immunotherapy combined with chemotherapy versus monotherapy in solid tumors: a meta-analysis of randomized clinical trials.

Oncotarget. Article. 10(35):3294-3301.
[doi:10.18632/oncotarget.26908]
Fizazi, K, Tran, N, Fein, L, Matsubara, N, Rodriguez-Antolin, A, Alekseev, BY, Ozguroglu, M, Ye, DW, Feyerabend, S, Protheroe, A, Sulur, G, Luna, Y, Li, S, Mundle, S, Chi, KN (2019).

Abiraterone acetate plus prednisone in patients with newly Croatia& diagnosed high-risk metastatic castration-sensitive prostate cancer (LATITUDE): final overall survival analysis of a randomised, double-blind, phase 3 trial

LANCET ONCOLOGY. Article. 20(5):686-700.
[doi:10.1016/S1470-2045(19)30082-8]
Garcia-Rojo, E, Medina-Polo, J, Sopena-Sutil, R, Guerrero-Ramos, F, Garcia-Gomez, B, Aguilar-Gisbert, L, Garcia-Alvarez, G, Azcutia-Gomez, MR, Gomez-Martin, F, Molero-Garcia, JM, Pereda-Arregui, E, Vargas-Machuca Cabanero MC, Villacampa-Auba, F, Tejido Sanchez A (2019).

Analysis of referrals after a synergic work between Primary Care and Urology. Impact of joint protocol implementation and a continuing education program in our healthcare area.

ACTAS UROLOGICAS ESPANOLAS. Article. 43(4):176-181.
[doi:10.1016/j.acuro.2018.10.001]
Rubio, C, Munera-Maravilla, E, Lodewijk, I, Suarez-Cabrera, C, Karaivanova, V, Ruiz-Palomares, R, Paramio, JM, Duenas, M (2019).

Macrophage polarization as a novel weapon in conditioning tumor microenvironment for bladder cancer: can we turn demons into gods?

CLINICAL & TRANSLATIONAL ONCOLOGY. Review. 21(4):391-403.
[doi:10.1007/s12094-018-1952-y]
Benitez-Sala, R, Medina-Polo, J, Justo-Quintas, J, Gil-Moradillo, J, Perez-Cadavid, S, Arrebola-Pajares, A, Sopena-Sutil, R, Lara-Isla, A, Alonso-Isa, M, Gonzalez-Padilla, DA, Garcia-Rojo, E, Miranda-Utrera, N, Aguilar-Gisbert, L, Tejido-Sanchez, A (2019).

Infections related to healthcare in patients hospitalized in a Urology service: resistance patterns and adequacy of empirical antibiotic treatment as a prognostic factor.

ACTAS UROLOGICAS ESPANOLAS. Article. 43(3):151-157.
[doi:10.1016/j.acuro.2018.08.004]
Garcia-Sanz, R, Sureda, A, de la Cruz, F, Canales, M, Gonzalez, AP, Pinana, JL, Rodriguez, A, Gutierrez, A, Domingo-Domenech, E, Sanchez-Gonzalez, B, Rodriguez, G, Lopez, J, Moreno, M, Rodriguez-Salazar, MJ, Jimenez-Cabrera, S, Caballero, MD, Martinez, C (2019).

Brentuximab Vedotin and ESHAP is Highly Effective as Second-Line Therapy for Hodgkin Lymphoma Patients (Long-Term Results of a Trial by the Spanish GELTAMO Group).

ANNALS OF ONCOLOGY. Article. 30(4):612-620.
[doi:10.1093/annonc/mdz009]
Gonzalez-Padilla DA, Gonzalez-Diaz A, Garcia-Gomez B, Villacampa-Aub, F, Miranda-Utrera, N, Rodriguez-Antolin A, Guerrero-Ramos, F (2019).

Cystoscopy Real-Time Self-Visualization and Its Impact in Patient's Pain Perception

JOURNAL OF ENDOUROLOGY. Article. 33(4):309-313.
[doi:10.1089/end.2018.0768]
Perez-Gracia, JL, Castellano, D, Climent, MA, Mellado, B, Suarez, C (2019).

Best treatment options for advanced renal cell carcinoma (RCC) patients: a Delphi consensus study

MEDICAL ONCOLOGY. Article. 36(3):29-29.
[doi:10.1007/s12032-019-1251-7]
Page, A, Ortega, A, Alameda, JP, Navarro, M, Paramio, JM, Saiz-Pardo, M, Almeida, EI, Hernandez, P, Fernandez-Acenero, MJ, Garcia-Fernandez, RA, Casanova, ML (2019).

IKKa Promotes the Progression and Metastasis of Non-Small Cell Lung Cancer Independently of its Subcellular Localization.

Computational and Structural Biotechnology Journal. Article. 17:251-262.
[doi:10.1016/j.csbj.2019.02.003]
Auvray M, Auclin E, Barthelemy P, Bono P, Kellokumpu-Lehtinen P, Gross-Goupil M, De Velasco G, Powles T, Mouillet G, Vano YA, Gravis G, Mourey L, Priou F, Rolland F, Escudier B, Albiges L (2019).

Second-line targeted therapies after nivolumab-ipilimumab failure in metastatic renal cell carcinoma.

EUROPEAN JOURNAL OF CANCER. Article. 108:33-40.
[doi:10.1016/j.ejca.2018.11.031]
Molina, M, Guerrero-Ramos, F, Fernandez-Ruiz, M, Gonzalez, E, Cabrera, J, Morales, E, Gutierrez, E, Hernandez, E, Polanco, N, Hernandez, A, Praga, M, Rodriguez-Antolin, A, Pamplona, M, de la Rosa, F, Cavero, T, Chico, M, Villar, A, Justo, I, Andres, A (2019).

Kidney transplant from uncontrolled donation after circulatory death donors maintained by nECMO has long-term outcomes comparable to standard criteria donation after brain death

AMERICAN JOURNAL OF TRANSPLANTATION. Article. 19(2):434-447.
[doi:10.1111/ajt.14991]
Puig P, Erill N, Terricabras M, Subirana I, González-García J, Asensi-Puig A, Donovan MJ, Mengual L, Agulló-Ortuño MT, Olivan M, Alcaraz A, López-Martín JA, de Torres I, Rodríguez-Peralto JL, Rodríguez-Antolín A, Morote J, González-Rumayor V (2019).

Multiple immunofluorescence assay identifies upregulation of Active ß-catenin in prostate cancer.

BMC research notes. Article. 12(1):68-68.
[doi:10.1186/s13104-019-4100-z]
Alameda, JP, Ramirez, A, Garcia-Fernandez, RA, Navarro, M, Page, A, Segovia, JC, Sanchez, R, Suarez-Cabrera, C, Paramio, JM, Bravo, A, Fernandez-Acenero, MJ, Casanova, ML (2019).

Premature aging and cancer development in transgenic mice lacking functional CYLD

Aging-Us. Article. 11(1):127-159.
[doi:10.18632/aging.101732]
Lorenzo-Martin, LF, Citterio, C, Menacho-Marquez, M, Conde, J, Larive, RM, Rodriguez-Fdez, S, Garcia-Escudero, R, Robles-Valero, J, Cuadrado, M, Fernandez-Pisonero, I, Dosil, M, Sevilla, MA, Montero, MJ, Fernandez-Salguero, PM, Paramio, JM, Bustelo, XR (2019).

Vav proteins maintain epithelial traits in breast cancer cells using miR-200c-dependent and independent mechanisms

ONCOGENE. Article. 38(2):209-227.
[doi:10.1038/s41388-018-0433-7]
Capdevila J, Teulé A, Barriuso J, Castellano D, Lopez C, Manzano JL, Alonso V, García-Carbonero R, Dotor E, Matos I, Custodio A, Casanovas O, Salazar R, EVERLAR study investigators (2019).

Phase II Study of Everolimus and Octreotide LAR in Patients with Nonfunctioning Gastrointestinal Neuroendocrine Tumors: The GETNE1003_EVERLAR Study

ONCOLOGIST. Article. 24(1):38-46.
[doi:10.1634/theoncologist.2017-0622]
Bernardini, A, Cuesta, T, Tomas, A, Bengoechea, J, Martinez, J, Sanchez, MB (2019).

The intrinsic resistome of Klebsiella pneumoniae

INTERNATIONAL JOURNAL OF ANTIMICROBIAL AGENTS. Article. 53(1):29-33.
[doi:10.1016/j.ijantimicag.2018.09.012]
Hakenberg, OW, Perez-Gracia, JL, Castellano, D, Demkow, T, Ali, T, Caffo, O, Heidenreich, A, Schultze-Seemann, W, Sautois, B, Pavlik, I, Qin, A, Novosiadly, RD, Shahir, A, Ilaria R Jr, Nippgen, J (2019).

Randomised phase II study of second-line olaratumab with mitoxantrone/prednisone versus mitoxantrone/prednisone alone in metastatic castration-resistant prostate cancer

EUROPEAN JOURNAL OF CANCER. Article. 107:186-195.
[doi:10.1016/j.ejca.2018.10.005]
Gonzalez Del Alba A, De Velasco G, Lainez N, Maroto P, Morales-Barrera R, Munoz-Langa J, Perez-Valderrama B, Basterretxea L, Caballero C, Vazquez S (2019).

SEOM clinical guideline for treatment of muscle-invasive and metastatic urothelial bladder cancer (2018)

CLINICAL & TRANSLATIONAL ONCOLOGY. Article. 21(1):64-74.
[doi:10.1007/s12094-018-02001-x]
Rubio, C, Martinez-Fernandez, M, Segovia, C, Lodewijk, I, Suarez-Cabrera, C, Segrelles, C, Lopez-Calderon, F, Munera-Maravilla, E, Santos, M, Bernardini, A, Garcia-Escudero, R, Lorz, C, Gomez-Rodriguez, MJ, de Velasco, G, Otero, I, Villacampa, F, Guerrero-Ramos, F, Ruiz, S, de la Rosa, F, Dominguez-Rodriguez, S, Real, FX, Malats, N, Castellano, D, Duenas, M, Paramio, JM (2019).

CDK4/6 Inhibitor as a Novel Therapeutic Approach for Advanced Bladder Cancer Independently of RB1 Status

CLINICAL CANCER RESEARCH. Article. 25(1):390-402.
[doi:10.1158/1078-0432.CCR-18-0685]

2018

Caries, J, Castellano, D, Mendez-Vidal, MJ, Mellado, B, Saez, MI, del Alba, AG, Perez-Gracia, JL, Jimenez, J, Suarez, C, Sepulveda, JM, Manneh, R, Porras, I, Lopez, C, Morales-Barrera, R, Arranz, JA (2018).

Circulating Tumor Cells as a Biomarker of Survival and Response to Radium-223 Therapy: Experience in a Cohort of Patients With Metastatic Castration-Resistant Prostate Cancer

CLINICAL GENITOURINARY CANCER. Article. 16(6):1133-1139.
[doi:10.1016/j.clgc.2018.07.013]
Segrelles C, Paramio JM, Lorz C (2018).

The transcriptional co-activator YAP: A new player in head and neck cancer

ORAL ONCOLOGY. Review. 86:25-32.
[doi:10.1016/j.oraloncology.2018.08.020]
Korkut, A, Zaidi, S, Kanchi, RS, Rao, SY, Gough, NR, Schultz, A, Li, XB, Lorenzi, PL, Berger, AC, Robertson, G, Kwong, LN, Datto, M, Roszik, J, Ling, SY, Ravikumar, V, Manyam, G, Rao, A, Shelley, S, Liu, YX, Ju, ZL, Hansel, D, de Velasco, G, Pennathur, A, Andersen, JB, O'Rourke, CJ, Ohshiro, K, Jogunoori, W, Nguyen, BN, Li, SL, Osmanbeyoglu, HU, Ajani, JA, Mani, SA, Houseman, A, Wiznerowicz, M, Chen, J, Gu, SJ, Ma, WC, Zhang, JX, Tong, P, Cherniack, AD, Deng, CX, Resar, L, Weinstein, JN, Mishra, L, Akbani, R, Canc Genome Atlas Res Network (2018).

A Pan-Cancer Analysis Reveals High-Frequency Genetic Alterations in Mediators of Signaling by the TGF-beta Superfamily

Cell Systems. Article. 7(4):422.
[doi:10.1016/j.cels.2018.08.010]
Lodewijk, I, Duenas, M, Rubio, C, Munera-Maravilla, E, Segovia, C, Bernardini, A, Teijeira, A, Paramio, JM, Suarez-Cabrera, C (2018).

Liquid Biopsy Biomarkers in Bladder Cancer: A Current Need for Patient Diagnosis and Monitoring

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 19(9).
[doi:10.3390/ijms19092514]
Chen J, Guccini I, Di Mitri D, Brina D, Revandkar A, Sarti M, Pasquini E, Alajati A, Pinton S, Losa M, Civenni G, Catapano CV, Sgrignani J, Cavalli A, D'Antuono R, Asara JM, Morandi A, Chiarugi P, Crotti S, Agostini M, Montopoli M, Masgras I, Rasola A, Garcia-Escudero R, Delaleu N, Rinaldi A, Bertoni F, de Bono J, Carracedo A, Alimonti A (2018).

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer (vol 50, pg 219, 2018)

NATURE GENETICS. Correction. 50(9):1343-1343.
[doi:10.1038/s41588-018-0181-1]
Angelergues, A, Efstathiou, E, Gyftaki, R, Wysocki, PJ, Lainez, N, Gonzalez, I, Castellano, DE, Ozguroglu, M, Carbonero, IG, Flechon, A, Borrega, P, Guillot, A, Balea, BC, Le Moulec, S, Esteban, E, Munarriz, J, Rubio, G, Birtle, AJ, Delanoy, N, Bellmunt, J, Oudard, S (2018).

Results of the FLAC European Database of Metastatic Castration-Resistant Prostate Cancer Patients Treated With Docetaxel, Cabazitaxel, and Androgen Receptor-Targeted Agents

CLINICAL GENITOURINARY CANCER. Article. 16(4):777-784.
[doi:10.1016/j.clgc.2018.02.016]
McKay, RR, Bosse, D, Xie, WL, Wankowicz SAM, Flaifel, A, Brandao, R, Lalani, AKA, Martini, DJ, Wei, XX, Braun, DA, Van Allen, E, Castellano, D, De Velasco, G, Wells, JC, Heng DYC, Fay, AP, Schutz, FA, Hsu, J, Pal, SK, Lee, JL, Hsieh, JJ, Harshman, LC, Signoretti, S, Motzer, RJ, Feldman, D, Choueiri, TK (2018).

The Clinical Activity of PD-1/PD-L1 Inhibitors in Metastatic Non-Clear Cell Renal Cell Carcinoma

Cancer Immunology Research. Article. 6(7):758-765.
[doi:10.1158/2326-6066.CIR-17-0475]
Segrelles, C, Contreras, D, Navarro, EM, Gutierrez-Munoz, C, Garcia-Escudero, R, Paramio, JM, Lorz, C (2018).

Bosutinib Inhibits EGFR Activation in Head and Neck Cancer

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 19(7).
[doi:10.3390/ijms19071824]
Castellano, D, Maroto, JP, Espinosa, E, Grande, E, Bolos V, Linares J, Esteban, E, Gonzalez Del Alba A, Climent, MA, Arranz, JA, Mendez, MJ, Fernadez Parra E, Anton-Aparicio, L, Bayona, C, Gallegos, I, Gallardo, E, Samaniego, L, Garcia Donas J (2018).

Experience with Sunitinib in metastatic renal cell carcinoma (mRCC) patients: pooled analysis from 3 Spanish observational prospective studies

EXPERT OPINION ON DRUG SAFETY. Article. 17(6):573-579.
[doi:10.1080/14740338.2017.1330410]
Carretero-Gonzalez, A, Otero, I, Carril-Ajuria, L, de Velasco, G, Manso, L (2018).

Exosomes: Definition, Role in Tumor Development and Clinical Implications

CANCER MICROENVIRONMENT. Review. 11(1):13-21.
[doi:10.1007/s12307-018-0211-7]
Liu, XY, Swen, JJ, Diekstra, MHM, Boven, E, Castellano, D, Gelderblom, H, Mathijssen, RHJ, Vermeulen, SH, Oosterwijk, E, Junker, K, Roessler, M, Alexiusdottir, K, Sverrisdottir, A, Radu, MT, Ambert, V, Eisen, T, Warren, A, Rodriguez-Antona, C, Garcia-Donas, J, Bohringer, S, Koudijs, KKM, Kiemeney, LALM, Rini, BI, Guchelaar, HJ (2018).

A Genetic Polymorphism in CTLA-4 Is Associated with Overall Survival in Sunitinib-Treated Patients with Clear Cell Metastatic Renal Cell Carcinoma

CLINICAL CANCER RESEARCH. Article. 24(10):2350-2356.
[doi:10.1158/1078-0432.CCR-17-2815]
Guerrero-Ramos, F, Castellano-Gauna, D, Garcia-Rojo, E, Duarte-Ojeda, JM, de la Rosa-Kehrmann, F, Villacampa-Auba, F (2018).

Mitomycin C HIVEC. Update and results in high risk patients

ARCHIVOS ESPANOLES DE UROLOGIA. Article. 71(4):417-425.
de Velasco, G, Wankowicz, SA, Madison, R, Ali, SM, Norton, C, Duquette, A, Ross, JS, Bosse, D, Lalani, AKA, Miller, VA, Stephens, PJ, Young, L, Hakimi, AA, Signoretti, S, Pal, SK, Choueiri, TK (2018).

Targeted genomic landscape of metastases compared to primary tumours in clear cell metastatic renal cell carcinoma

BRITISH JOURNAL OF CANCER. Article. 118(9):1238-1242.
[doi:10.1038/s41416-018-0064-3]
Motzer, RJ, Tannir, NM, McDermott, DF, Frontera, OA, Melichar, B, Choueiri, TK, Plimack, ER, Barthelemy, P, Porta, C, George, S, Powles, T, Donskov, F, Neiman, V, Kollmannsberger, CK, Salman, P, Gurney, H, Hawkins, R, Ravaud, A, Grimm, MO, Bracarda, S, Barrios, CH, Tomita, Y, Castellano, D, Rini, BI, Chen, AC, Mekan, S, McHenry, MB, Wind-Rotolo, M, Doan, J, Sharma, P, Hammers, HJ, Escudier, B, CheckMate 214 Investigators (2018).

Nivolumab plus Ipilimumab versus Sunitinib in Advanced Renal-Cell Carcinoma

NEW ENGLAND JOURNAL OF MEDICINE. Article. 378(14):1277-1290.
[doi:10.1056/NEJMoa1712126]
Garcia-Escudero, R, Segrelles, C, Duenas, M, Pombo, M, Ballestin, C, Alonso-Riano, M, Nenclares, P, Alvarez-Rodriguez, R, Sanchez-Aniceto, G, Ruiz-Alonso, A, Lopez-Cedrun, JL, Paramio, JM, Lorz, C (2018).

Overexpression of PIK3CA in head and neck squamous cell carcinoma is associated with poor outcome and activation of the YAP pathway

ORAL ONCOLOGY. Article. 79:55-63.
[doi:10.1016/j.oraloncology.2018.02.014]
Nuñez-Valdovinos B, Carmona-Bayonas, A, Jimenez-Fonseca, P, Capdevila, J, Castaño-Pascual Á, Benavent, M, Pi Barrio JJ, Teule, A, Alonso, V, Custodio, A, Marazuela, M, Segura, A, Beguiristain, A, Llanos, M, Martinez Del Prado MP, Diaz-Perez, JA, Castellano, D, Sevilla, I, Lopez, C, Alonso, T, Garcia-Carbonero, R (2018).

Neuroendocrine Tumor Heterogeneity Adds Uncertainty to the World Health Organization 2010 Classification: Real-World Data from the Spanish Tumor Registry (R-GETNE)

ONCOLOGIST. Article. 23(4):422-432.
[doi:10.1634/theoncologist.2017-0364]
Escudier B, Sharma P, McDermott DF, George S, Hammers HJ, Srinivas S, Tykodi SS, Sosman JA, Procopio G, Plimack ER, Castellano D, Gurney H, Donskov F, Peltola K, Wagstaff J, Gauler TC, Ueda T, Zhao H, Waxman IM, Motzer RJ, CheckMate 025 investigators (2018).

CheckMate 025 Randomized Phase 3 Study: Outcomes by Key Baseline Factors and Prior Therapy for Nivolumab Versus Everolimus in Advanced Renal Cell Carcinoma (vol 72, pg 962, 2017)

EUROPEAN UROLOGY. Correction. 73(4):116-118.
[doi:10.1016/j.eururo.2017.12.016]
Escudier, B, Powles, T, Motzer, RJ, Olencki, T, Arén Frontera O, Oudard, S, Rolland, F, Tomczak, P, Castellano, D, Appleman, LJ, Drabkin, H, Vaena, D, Milwee, S, Youkstetter, J, Lougheed, JC, Bracarda, S, Choueiri, TK (2018).

Cabozantinib, a New Standard of Care for Patients With Advanced Renal Cell Carcinoma and Bone Metastases? Subgroup Analysis of the METEOR Trial

JOURNAL OF CLINICAL ONCOLOGY. Article. 36(8):765-772.
[doi:10.1200/JCO.2017.74.7352]
Liu, X, Swen, J, Diekstra, M, Boven, E, Castellano, D, Gelderblom, H, Mathijssen, R, Vermeulen, S, Oosterwijk, E, Junker, K, Roessler, M, Rafnar, T, Radu, M, Eisen, T, Rodriguez-Antona, C, Garcia-Donas, J, Bohringer, S, Kiemeney, L, Rini, B, Guchelaar, HJ (2018).

A GENETIC POLYMORPHISM IN CTLA-4 IS ASSOCIATED WITH OVERALL SURVIVAL OF SUNITINIB-TREATED PATIENTS WITH CLEAR CELL METASTATIC RENAL CELL CARCINOMA.

CLINICAL PHARMACOLOGY & THERAPEUTICS. Meeting Abstract. 103:42-42.
Powles, T, Duran, I, van der Heijden, MS, Loriot, Y, Vogelzang, NJ, De Giorgi, U, Oudard, S, Retz, MM, Castellano, D, Bamias, A, Flechon, A, Gravis, G, Hussain, S, Takano, T, Leng, N, Kadel, EE, Banchereau, R, Hegde, PS, Mariathasan, S, Cui, N, Shen, XD, Derleth, CL, Green, MC, Ravaud, A (2018).

Atezolizumab versus chemotherapy in patients with platinum-treated locally advanced or metastatic urothelial carcinoma (IMvigor211): a multicentre, open-label, phase 3 randomised controlled trial

LANCET. Article. 391(10122):748-757.
[doi:10.1016/S0140-6736(17)33297-X]
Carretero-Gonzalez A, Lora D, Ghanem I, Zugazagoitia J, Castellano D, Sepulveda JM, Lopez-Martin JA, Paz-Ares L, de Velasco G (2018).

Analysis of response rate with ANTI PD1/PD-L1 monoclonal antibodies in advanced solid tumors: a meta-analysis of randomized clinical trials.

Oncotarget. Article. 9(9):8706-8715.
[doi:10.18632/oncotarget.24283]
Chen, JJ, Guccini, I, Mitri DD, Brina, D, Revandkar, A, Sarti, M, Pasquini, E, Alajati, A, Pinton, S, Losa, M, Civenni, G, Catapano, CV, Sgrignani, J, Cavalli, A, D'Antuono, R, Asara, JM, Morandi, A, Chiarugi, P, Crotti, S, Agostini, M, Montopoli, M, Masgras, I, Rasola, A, Garcia-Escudero, R, Delaleu, N, Rinaldi, A, Bertoni, F, Bono J, Carracedo, A, Alimonti, A (2018).

Compartmentalized activities of the pyruvate dehydrogenase complex sustain lipogenesis in prostate cancer

NATURE GENETICS. Article. 50(2):219-228.
[doi:10.1038/s41588-017-0026-3]
Gillessen, S, Attard, G, Beer, TM, Beltran, H, Bossi, A, Bristow, R, Carver, B, Castellano, D, Chung, BH, Clarke, N, Daugaard, G, Davis, ID, de Bono, J, dos Reis, RB, Drake, CG, Eeles, R, Efstathiou, E, Evans, CP, Fanti, S, Feng, F, Fizazi, K, Frydenberg, M, Gleave, M, Halabi, S, Heidenreich, A, Higano, CS, James, N, Kantoff, P, Kellokumpu-Lehtinen, PL, Khauli, RB, Kramer, G, Logothetis, C, Maluf, F, Morgans, AK, Morris, MJ, Mottet, N, Murthy, V, Oh, W, Ost, P, Padhani, AR, Parker, C, Pritchard, CC, Roach, M, Rubin, MA, Ryan, C, Saad, F, Sartor, O, Scher, H, Sella, A, Shore, N, Smith, M, Soule, H, Sternberg, CN, Suzuki, H, Sweeney, C, Sydes, MR, Tannock, I, Tombal, B, Valdagni, R, Wiegel, T, Omlin, A (2018).

Management of Patients with Advanced Prostate Cancer: The Report of the Advanced Prostate Cancer Consensus Conference APCCC 2017

EUROPEAN UROLOGY. Article. 73(2):178-211.
[doi:10.1016/j.eururo.2017.06.002]
Sharma, P, Tykodi, SS, Escudier, B, Carducci, M, Oudard, S, Hammers, HJ, George, S, Gauna, DC, Alva, AS, Richardet, ME, Chevreau, C, Plimack, ER, Srinivas, S, Procopio, G, Sosman, JA, McDermott, D, Choueiri, TK, Gauler, T, Berghorn, E, Yang, L, Motzer, R (2018).

Three-Year Efficacy and Safety Update From the Phase III Checkmate 025 Study of Nivolumab (NIVO) v Everolimus (EVE) in Patients With Advanced Renal Cell Carcinoma (aRCC)

ONCOLOGY RESEARCH AND TREATMENT. Meeting Abstract. 41:78-78.
Cordero, JG, Garcia-Escudero, R, Avila, J, Gargini, R, Garcia-Escudero, V (2018).

Benefit of Oleuropein Aglycone for Alzheimer's Disease by Promoting Autophagy

Oxidative Medicine And Cellular Longevity. Review. 2018:5010741-5010741.
[doi:10.1155/2018/5010741]
Carles, J, Mendez, MJ, Pinto, A, Saez, MI, Arranz, JA, Maroto, P, Lopez-Criado, P, Mellado, B, Donas, JG, Hernando, S, Leon, L, del Alba, AG, Lainez, N, Esteban, E, Reynes, G, Perez-Gracia, JL, Germa, JR, Lopez-Brea, M, Perez-Valderrama, B, Moretones, C, Castellano, D (2018).

Radium-223 international early access program: results from the Spanish subset

FUTURE ONCOLOGY. Article. 14(1):41-50.
[doi:10.2217/fon-2017-0297]

2017

Page A, Navarro M, Suárez-Cabrera C, Bravo A, Ramirez A (2017).

Context-Dependent Role of IKKß in Cancer.

Genes. Article. 8(12).
[doi:10.3390/genes8120376]
Escudier B, Sharma P, McDermott DF, George S, Hammers HJ, Srinivas S, Tykodi SS, Sosman JA, Procopio G, Plimack ER, Castellano D, Gurney H, Donskov F, Peltola K, Wagstaff J, Gauler TC, Ueda T, Zhao H, Waxman IM, Motzer RJ, CheckMate 025 investigators (2017).

CheckMate 025 Randomized Phase 3 Study: Outcomes by Key Baseline Factors; and Prior Therapy for Nivolumab Versus Everolimus in Advanced Renal Cell; Carcinoma

EUROPEAN UROLOGY. Article. 72(6):962-971.
[doi:10.1016/j.eururo.2017.02.010]
Climent MÁ, Pérez-Valderrama B, Mellado B, Fernández Parra EM, Fernández Calvo O, Ochoa de Olza M, Muinelo Romay L, Anido U, Domenech M, Hernando Polo S, Arranz Arija JÁ, Caballero C, Juan Fita MJ, Castellano D (2017).

Weekly cabazitaxel plus prednisone is effective and less toxic for; 'unfit' metastatic castration-resistant prostate cancer: Phase II; Spanish Oncology Genitourinary Group (SOGUG) trial

EUROPEAN JOURNAL OF CANCER. Article. 87:30-37.
[doi:10.1016/j.ejca.2017.09.028]
Segovia C, Paramio JM (2017).

Ezh2-dependent therapies in bladder cancer: synthetic lethality

Annals of translational medicine. Editorial Material. 5(24):494-494.
[doi:10.21037/atm.2017.10.08]
Martínez VG, Rubio C, Martínez-Fernández M, Segovia C, López-Calderón F, Garín M, Teijeira A, Munera-Maravilla E, Varas A, Sacedón R, Guerrero-Ramos F, Villacampa F, de la Rosa F, Castellano D, López-Collazo E, Paramio JM, Vicente Á, Dueñas M (2017).

BMP4 Induces M2 Macrophage Polarization and Favors Tumor Progression in; Bladder Cancer

CLINICAL CANCER RESEARCH. Article. 23(23):7388-7399.
[doi:10.1158/1078-0432.CCR-17-1004]
de Velasco G, McKay RR, Lin X, Moreira RB, Simantov R, Choueiri TK (2017).

Comprehensive Analysis of Survival Outcomes in Non-Clear Cell Renal Cell; Carcinoma Patients Treated in Clinical Trials

CLINICAL GENITOURINARY CANCER. Article. 15(6):652.
[doi:10.1016/j.clgc.2017.03.004]
Sevillano E, Werner L, Bossé D, Lalani AA, Wankowicz SAM, de Velasco G, Farina M, Lundgren K, Choueiri TK, González Del Alba A, Bellmunt J (2017).

Upper Tract Urothelial Carcinomas: Prognostic Factors and Outcomes in; Patients With Non-Lymph Node Distant Metastasis

CLINICAL GENITOURINARY CANCER. Article. 15(6):1089-1094.
[doi:10.1016/j.clgc.2017.07.012]
de Velasco G, Culhane AC, Heng DYC, Signoretti S, Choueiri TK (2017).

The Issue of Tissue in Molecular Stratification Reply

ONCOLOGIST. Letter. 22(12):1561-1561.
[doi:10.1634/theoncologist.2017-0283]
Petrylak DP, de Wit R, Chi KN, Drakaki A, Sternberg CN, Nishiyama H, Castellano D, Hussain S, Fléchon A, Bamias A, Yu EY, van der Heijden MS, Matsubara N, Alekseev B, Necchi A, Géczi L, Ou YC, Coskun HS, Su WP, Hegemann M, Percent IJ, Lee JL, Tucci M, Semenov A, Laestadius F, Peer A, Tortora G, Safina S, Del Muro XG, Rodriguez-Vida A, Cicin I, Harputluoglu H, Widau RC, Liepa AM, Walgren RA, Hamid O, Zimmermann AH, Bell-McGuinn KM, Powles T, RANGE study investigators (2017).

Ramucirumab plus docetaxel versus placebo plus docetaxel in patients; with locally advanced or metastatic urothelial carcinoma after; platinum-based therapy (RANGE): a randomised, double-blind, phase 3; trial

LANCET. Article. 390(10109):2266-2277.
[doi:10.1016/S0140-6736(17)32365-6]
de Velasco G, Trilla-Fuertes L, Gamez-Pozo A, Urbanowicz M, Ruiz-Ares G, Sepúlveda JM, Prado-Vazquez G, Arevalillo JM, Zapater-Moros A, Navarro H, Lopez-Vacas R, Manneh R, Otero I, Villacampa F, Paramio JM, Vara JAF, Castellano D (2017).

Urothelial cancer proteomics provides both prognostic and functional; information

SCIENTIFIC REPORTS. Article. 7(1):15819-15819.
[doi:10.1038/s41598-017-15920-6]
Guerrero-Ramos F, Lara-Isla A, Justo-Quintas J, Duarte-Ojeda JM, de la Rosa-Kehrmann F, Villacampa-Aubá F (2017).

Adjuvant intravesical treatment for nonmuscle invasive bladder cancer:; The importance of the strain and maintenance

ACTAS UROLOGICAS ESPANOLAS. Article. 41(9):590-595.
[doi:10.1016/j.acuro.2017.03.003]
Balar AV, Castellano D, O'Donnell PH, Grivas P, Vuky J, Powles T, Plimack ER, Hahn NM, de Wit R, Pang L, Savage MJ, Perini RF, Keefe SM, Bajorin D, Bellmunt J (2017).

First-line pembrolizumab in cisplatin-ineligible patients with locally; advanced and unresectable or metastatic urothelial cancer (KEYNOTE-052):; a multicentre, single-arm, phase 2 study

LANCET ONCOLOGY. Article. 18(11):1483-1492.
[doi:10.1016/S1470-2045(17)30616]
Oudard S, Fizazi K, Sengeløv L, Daugaard G, Saad F, Hansen S, Hjälm-Eriksson M, Jassem J, Thiery-Vuillemin A, Caffo O, Castellano D, Mainwaring PN, Bernard J, Shen L, Chadjaa M, Sartor O (2017).

Cabazitaxel Versus Docetaxel As First-Line Therapy for Patients With; Metastatic Castration-Resistant Prostate Cancer: A Randomized Phase III; Trial-FIRSTANA

JOURNAL OF CLINICAL ONCOLOGY. Article. 35(28):3189-3197.
[doi:10.1200/JCO.2016.72.1068]
Bellmunt J, Eigl BJ, Senkus E, Loriot Y, Twardowski P, Castellano D, Blais N, Sridhar SS, Sternberg CN, Retz M, Pal S, Blumenstein B, Jacobs C, Stewart PS, Petrylak DP (2017).

Borealis-1: a randomized, first-line, placebo-controlled, phase II study; evaluating apatorsen and chemotherapy for patients with advanced; urothelial cancer

ANNALS OF ONCOLOGY. Article. 28(10):2481-2488.
[doi:10.1093/annonc/mdx400]
Perez-Montero, H, Bonel, AC, Fasano, M, Pedraza, S, Guardado, S, Mendoza, AMC, Gascon, N, Asiain, L, Nenclares, P, Sanz, A, Dura, J, Mera, A, Perez-Escutia, MA, Bartolome, A, Perez-Regadera, J, Castellano, D, Villacampa, F, Cabeza, MA (2017).

Long-Term Outcomes of Organ Preservation for Bladder Cancer in a Large; Cohort

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. Meeting Abstract. 99(2):259-259.
[doi:10.1016/j.ijrobp.2017.06.1223]
Guerrero-Ramos F, Cavero-Escribano T, Rodríguez-Antolín A, Andrés-Belmonte A, Passas-Martínez J, Tejido-Sánchez Á (2017).

Perigraft fluid collections after kidney transplantation: Does the type; of donor (uncontrolled donation after circulatory death vs. donation; after brain death) have a role?

Central European Journal Of Urology. Article. 70(4):439-444.
[doi:10.5173/ceju.2017.1255]
Page A, Bravo A, Suarez-Cabrera C, Alameda JP, Casanova ML, Lorz C, Segrelles C, Segovia JC, Paramio JM, Navarro M, Ramirez A (2017).

IKK beta-Mediated Resistance to Skin Cancer Development Is; Ink4a/Arf-Dependent

MOLECULAR CANCER RESEARCH. Article. 15(9):1255-1264.
[doi:10.1158/1541-7786.MCR-17-0157]
Massard C, Chi KN, Castellano D, de Bono J, Gravis G, Dirix L, Machiels JP, Mita A, Mellado B, Turri S, Maier J, Csonka D, Chakravartty A, Fizazi K (2017).

Phase Ib dose-finding study of abiraterone acetate plus buparlisib; (BKM120) or dactolisib (BEZ235) in patients with castration-resistant; prostate cancer (vol 76, pg 36, 2017)

EUROPEAN JOURNAL OF CANCER. Correction. 81:242-242.
[doi:10.1016/j.ejca.2017.05.003]
Meyer CP, Sun M, Karam JA, Leow JJ, de Velasco G, Pal SK, Chang SL, Trinh QD, Choueiri TK (2017).

Complications After Metastasectomy for Renal Cell Carcinoma-A; Population-based Assessment

EUROPEAN UROLOGY. Article. 72(2):171-174.
[doi:10.1016/j.eururo.2017.03.005]
van der Zanden LF, Vermeulen SH, Oskarsdottir A, Maurits JS, Diekstra MH, Ambert V, Cambon-Thomsen A, Castellano D, Fritsch A, Garcia Donas J, Guarch Troyas R, Guchelaar HJ, Hartmann A, Hulsbergen-van de Kaa C, Jaehde U, Junker K, Martinez-Cardus A, Masson G, Oosterwijk-Wakka J, Radu MT, Rafnar T, Rodriguez-Antona C, Roessler M, Ruijtenbeek R, Stefansson K, Warren A, Wessels L, Eisen T, Kiemeney LA, Oosterwijk E (2017).

Description of the EuroTARGET cohort: A European collaborative project; on TArgeted therapy in renal cell cancer-GEnetic- and tumor-related; biomarkers for response and toxicity

UROLOGIC ONCOLOGY-SEMINARS AND ORIGINAL INVESTIGATIONS. Article. 35(8).
[doi:10.1016/j.urolonc.2017.03.009]
Conteduca V, Wetterskog D, Sharabiani MTA, Grande E, Fernandez-Perez MP, Jayaram A, Salvi S, Castellano D, Romanel A, Lolli C, Casadio V, Gurioli G, Amadori D, Font A, Vazquez-Estevez S, González Del Alba A, Mellado B, Fernandez-Calvo O, Méndez-Vidal MJ, Climent MA, Duran I, Gallardo E, Rodriguez A, Santander C, Sáez MI, Puente J, Gasi Tandefelt D, Wingate A, Dearnaley D, PREMIERE Collaborators, Spanish Oncology Genitourinary Group, Demichelis F, De Giorgi U, Gonzalez-Billalabeitia E, Attard G (2017).

Androgen receptor gene status in plasma DNA associates with worse; outcome on enzalutamide or abiraterone for castration-resistant prostate; cancer: a multi-institution correlative biomarker study

ANNALS OF ONCOLOGY. Article. 28(7):1508-1516.
[doi:10.1093/annonc/mdx155]
Zhang Y, Kwok-Shing Ng P, Kucherlapati M, Chen F, Liu Y, Tsang YH, de Velasco G, Jeong KJ, Akbani R, Hadjipanayis A, Pantazi A, Bristow CA, Lee E, Mahadeshwar HS, Tang J, Zhang J, Yang L, Seth S, Lee S, Ren X, Song X, Sun H, Seidman J, Luquette LJ, Xi R, Chin L, Protopopov A, Westbrook TF, Shelley CS, Choueiri TK, Ittmann M, Van Waes C, Weinstein JN, Liang H, Henske EP, Godwin AK, Park PJ, Kucherlapati R, Scott KL, Mills GB, Kwiatkowski DJ, Creighton CJ (2017).

A Pan-Cancer Proteogenomic Atlas of PI3K/AKT/mTOR Pathway Alterations

CANCER CELL. Article. 31(6):820.
[doi:10.1016/j.ccell.2017.04.013]
Apellániz-Ruiz M, Diekstra MH, Roldán JM, Boven E, Castellano D, Gelderblom H, Mathijssen RHJ, Swen JJ, Böhringer S, García-Donás J, Rini BI, Guchelaar HJ, Rodríguez-Antona C (2017).

Evaluation of KDR rs34231037 as a predictor of sunitinib efficacy in; patients with metastatic renal cell carcinoma

PHARMACOGENETICS AND GENOMICS. Article. 27(6):227-231.
[doi:10.1097/FPC.0000000000000280]
De Velasco G, Xie W, Donskov F, Albiges L, Beuselinck B, Srinivas S, Agarwal N, Lee JL, Brugarolas J, Wood LA, Rha SY, Kollmannsberger C, North S, Kanesvaran R, Rini BI, Broom R, Yamamoto H, Kaymakcalan MD, Heng DY, Choueiri TK (2017).

Discontinuing VEGF-targeted Therapy for Progression Versus Toxicity; Affects Outcomes of Second-line Therapies in Metastatic Renal Cell; Carcinoma

CLINICAL GENITOURINARY CANCER. Article. 15(3):403-410.
[doi:10.1016/j.clgc.2017.01.005]
Puente J, Laínez N, Dueñas M, Méndez-Vidal MJ, Esteban E, Castellano D, Martinez-Fernández M, Basterretxea L, Juan-Fita MJ, Antón L, León L, Lambea J, Pérez-Valderrama B, Vázquez S, Suarez C, Del Muro XG, Gallardo E, Maroto JP, Samaniego ML, Suárez-Paniagua B, Sanz J, Paramio JM, SOGUG (Spanish Oncology Genitourinary Group) (2017).

Novel potential predictive markers of sunitinib outcomes in long-term; responders versus primary refractory patients with metastatic clear-cell; renal cell carcinoma

Oncotarget. Article. 8(18):30410-30421.
[doi:10.18632/oncotarget.16494]
Segovia, C, Paramio, JM, Martinez-Fernandez, M (2017).

Epigenetic mutations and cancer therapy Effectiven(EZH2)

Translational Cancer Research. Editorial Material. 6:629-634.
[doi:10.21037/tcr.2017.05.27]
García-Donas J, Font A, Pérez-Valderrama B, Virizuela JA, Climent MÁ, Hernando-Polo S, Arranz JÁ, Del Mar Llorente M, Lainez N, Villa-Guzmán JC, Mellado B, Del Alba AG, Castellano D, Gallardo E, Anido U, Del Muro XG, Domènech M, Puente J, Morales-Barrera R, Pérez-Gracia JL, Bellmunt J (2017).

Maintenance therapy with vinflunine plus best supportive care versus; best supportive care alone in patients with advanced urothelial; carcinoma with a response after first-line chemotherapy (MAJA; SOGUG; 2011/02): a multicentre, randomised, controlled, open-label, phase 2; trial

LANCET ONCOLOGY. Article. 18(5):672-681.
[doi:10.1016/S1470-2045(17)30242-5]
Geynisman DM, De Velasco G, Sewell KL, Jacobs I (2017).

Biosimilar biologic drugs: a new frontier in medical care

POSTGRADUATE MEDICINE. Review. 129(4):460-470.
[doi:10.1080/00325481.2017.1311196]
Massard C, Chi KN, Castellano D, de Bono J, Gravis G, Dirix L, Machiels JP, Mita A, Gonzalez BM, Turri S, Maier J, Csonka D, Chakravartty A, Fizazi K (2017).

Phase Ib dose-finding study of abiraterone acetate plus buparlisib; (BKM120) or dactolisib (BEZ235) in patients with castration-resistant; prostate cancer

EUROPEAN JOURNAL OF CANCER. Article. 76:36-44.
[doi:10.1016/j.ejca.2017.01.024]
de Lena PG, Paz-Gallardo A, Paramio JM, García-Escudero R (2017).

Clusterization in head and neck squamous carcinomas based on lncRNA; expression: molecular and clinical correlates

Clinical epigenetics. Article. 9:36-36.
[doi:10.1186/s13148-017-0334-6]
Capdevila J, Casanovas O, Salazar R, Castellano D, Segura A, Fuster P, Aller J, García-Carbonero R, Jimenez-Fonseca P, Grande E, Castaño JP (2017).

Translational research in neuroendocrine tumors: pitfalls and; opportunities

ONCOGENE. Review. 36(14):1899-1907.
[doi:10.1038/onc.2016.316]
González-Billalabeitia E, Sepúlveda JM, Maroto P, Aparicio J, Arranz JA, Esteban E, Gironés R, López-Brea M, Mendez-Vidal MJ, Pinto A, Sastre J, de Prado DS, Terrasa J, Vázquez S, Powles T, Beyer J, Castellano D, Del Muro XG, Spanish Germ Cell Cancer Group and the Spanish Oncology Genitourinary Group (2017).

Consensus Recommendations from the Spanish Germ Cell Cancer Group on the Use of High-dose Chemotherapy in Germ Cell Cancer.

European Urology Focus. Article. 3(2-3):280-286.
[doi:10.1016/j.euf.2016.07.002]
Loizaga-Iriarte A, Rodriguez-Antolin A, Miñana B, Lacasa-Viscasillas I, Senarriaga-Ruiz de la Illa N, Cozar-Olmo JM, Unda-Urzaiz M (2017).

Castrate resistant prostate cancer. Consensus recommendations of the; Spanish Association of Urology

ACTAS UROLOGICAS ESPANOLAS. Editorial Material. 41(3):141-145.
[doi:10.1016/j.acuro.2016.09.001]
De Velasco G, Je Y, Bossé D, Awad MM, Ott PA, Moreira RB, Schutz F, Bellmunt J, Sonpavde GP, Hodi FS, Choueiri TK (2017).

Comprehensive Meta-analysis of Key Immune-Related Adverse Events from; CTLA-4 and PD-1/PD-L1 Inhibitors in Cancer Patients

Cancer Immunology Research. Article. 5(4):312-318.
[doi:10.1158/2326-6066.CIR-16-0237]
Gonzalez-Billalabeitia E, Castellano D, Sobrevilla N, Guma J, Hervas D, Luengo MI, Aparicio J, Sanchez-Muñoz A, Mellado B, Saenz A, Valverde C, Fernandez A, Margeli M, Duran I, Fernandez S, Sastre J, Ros S, Maroto P, Manneh R, Cerezuela P, Carmona-Bayonas A, Spanish Germ Cell Cancer Group/Grupo Germinal (SGCCG) (2017).

Prognostic Significance of Venous Thromboembolic Events in Disseminated; Germ Cell Cancer Patients

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. Article. 109(4).
[doi:10.1093/jnci/djw265]
Page A, Navarro M, Suarez-Cabrera C, Alameda JP, Casanova ML, Paramio JM, Bravo A, Ramirez A (2017).

Protective role of p53 in skin cancer: Carcinogenesis studies in mice; lacking epidermal p53 (vol 7, pg 20902, 2016)

Oncotarget. Correction. 8(13):22304-22304.
[doi:10.18632/oncotarget.16592]
Suárez-Cabrera C, Quintana RM, Bravo A, Casanova ML, Page A, Alameda JP, Paramio JM, Maroto A, Salamanca J, Dupuy AJ, Ramírez A, Navarro M (2017).

A Transposon-based Analysis Reveals RASA1 Is Involved in Triple-Negative Breast Cancer

CANCER RESEARCH. Article. 77(6):1357-1368.
[doi:10.1158/0008-5472.CAN-16-1586]
Riveiro-Falkenbach E, Ruano Y, García-Martín RM, Lora D, Cifdaloz M, Acquadro F, Ballestin C, Ortiz-Romero PL, Soengas MS, Rodríguez-Peralto JL (2017).

DEK oncogene is overexpressed during melanoma progression

PIGMENT CELL & MELANOMA RESEARCH. Article. 30(2):194-202.
[doi:10.1111/pcmr.12563]
Jiménez-Romero C, Conde M, de la Rosa F, Manrique A, Calvo J, Caso Ó, Muñoz C, Marcacuzco A, Justo I (2017).

Treatment of caval vein thrombosis associated with renal tumors

CIRUGIA ESPANOLA. Article. 95(3):152-159.
[doi:10.1016/j.ciresp.2017.01.004]
de Velasco G, Culhane AC, Fay AP, Hakimi AA, Voss MH, Tannir NM, Tamboli P, Appleman LJ, Bellmunt J, Kimryn Rathmell W, Albiges L, Hsieh JJ, Heng DY, Signoretti S, Choueiri TK (2017).

Molecular Subtypes Improve Prognostic Value of International Metastatic; Renal Cell Carcinoma Database Consortium Prognostic Model

ONCOLOGIST. Article. 22(3):286-292.
[doi:10.1634/theoncologist.2016-0078]
González-Larriba JL, Maroto P, Durán I, Lambea J, Flores L, Castellano D, The Changing Group (2017).

The role of mTOR inhibition as second-line therapy in metastatic renal; carcinoma: clinical evidence and current challenges

EXPERT REVIEW OF ANTICANCER THERAPY. Review. 17(3):217-226.
[doi:10.1080/14737140.2017.1273774]
Segovia C, Martínez-Fernández M, Dueñas M, Rubio C, López-Calderón FF, Costa C, Saiz-Ladera C, Fernández-Grajera M, Duarte J, Muñoz HG, de la Rosa F, Villacampa F, Castellano D, Paramio JM (2017).

Opposing roles of PIK3CA gene alterations to EZH2 signaling in; non-muscle invasive bladder cancer

Oncotarget. Article. 8(6):10531-10542.
[doi:10.18632/oncotarget.14453]
Perez-Gracia JL, Sanmamed MF, Bosch A, Patiño-Garcia A, Schalper KA, Segura V, Bellmunt J, Tabernero J, Sweeney CJ, Choueiri TK, Martín M, Fusco JP, Rodriguez-Ruiz ME, Calvo A, Prior C, Paz-Ares L, Pio R, Gonzalez-Billalabeitia E, Gonzalez Hernandez A, Páez D, Piulats JM, Gurpide A, Andueza M, de Velasco G, Pazo R, Grande E, Nicolas P, Abad-Santos F, Garcia-Donas J, Castellano D, Pajares MJ, Suarez C, Colomer R, Montuenga LM, Melero I (2017).

Strategies to design clinical studies to identify predictive biomarkers; in cancer research

CANCER TREATMENT REVIEWS. Review. 53:79-97.
[doi:10.1016/j.ctrv.2016.12.005]
Faivre S, Niccoli P, Castellano D, Valle JW, Hammel P, Raoul JL, Vinik A, Van Cutsem E, Bang YJ, Lee SH, Borbath I, Lombard-Bohas C, Metrakos P, Smith D, Chen JS, Ruszniewski P, Seitz JF, Patyna S, Lu DR, Ishak KJ, Raymond E (2017).

Sunitinib in pancreatic neuroendocrine tumors: updated progression-free; survival and final overall survival from a phase III randomized study

ANNALS OF ONCOLOGY. Article. 28(2):339-343.
[doi:10.1093/annonc/mdw561]
Feber A, Dhami P, Dong L, de Winter P, Tan WS, Martínez-Fernández M, Paul DS, Hynes-Allen A, Rezaee S, Gurung P, Rodney S, Mehmood A, Villacampa F, de la Rosa F, Jameson C, Cheng KK, Zeegers MP, Bryan RT, James ND, Paramio JM, Freeman A, Beck S, Kelly JD (2017).

UroMark-a urinary biomarker assay for the detection of bladder cancer

Clinical epigenetics. Article. 9:8-8.
[doi:10.1186/s13148-016-0303-5]
Cebrian, Arancha, Gomez del Pulgar, Teresa, Jose Mendez-Vidal, Maria, Luisa Gonzalvez, Maria, Lainez, Nuria, Castellano, Daniel, Garcia-Carbonero, Iciar, Esteban, Emilio, Isabel Saez, Maria, Villatoro, Rosa, Suarez, Cristina, Carrato, Alfredo, Munarriz-Ferrandiz, Javier, Basterrechea, Laura, Garcia-Alonso, Mirta, Luis Gonzalez-Larriba, Jose, Perez-Valderrama, Begona, Cruz-Jurado, Josefina, Gonzalez del Alba, Aranzazu, Moreno, Fernando, Reynes, Gaspar, Rodriguez-Remirez, Maria, Boni, Valentina, Mahillo-Fernandez, Ignacio, Martin, Yolanda, Viqueira, Andrea, Garcia-Foncillas, Jesus (2017).

Functional PTGS2 polymorphism-based models as novel predictive markers; in metastatic renal cell carcinoma patients receiving first-line; sunitinib

SCIENTIFIC REPORTS. Article. 7.
[doi:10.1038/srep41371]
Lázaro S, Pérez-Crespo M, Enguita AB, Hernández P, Martínez-Palacio J, Oteo M, Sage J, Paramio JM, Santos M (2017).

Ablating all three retinoblastoma family members in mouse lung leads to; neuroendocrine tumor formation

Oncotarget. Article. 8(3):4373-4386.
[doi:10.18632/oncotarget.13875]
Liu X, Swen JJ, Boven E, Castellano D, Gelderblom H, Mathijssen RH, Rodríguez-Antona C, García-Donas J, Rini BI, Guchelaar HJ (2017).

Meta-analysis on the association of VEGFR1 genetic variants with; sunitinib outcome in metastatic renal cell carcinoma patients

Oncotarget. Article. 8(1):1204-1212.
[doi:10.18632/oncotarget.13597]
Lista, AGD, Necchi, A, Lavaud, P, Galceran, JC, Castellano, D, Ravaud, A, Duran, I, van Dijk, N, Giannatempo, P, Loriot, Y, Barrera, RM, De Rueda, GDO, Lefort, F, Bernal, GM, Raggi, D, Gross-Goupil, M, Powles, T, van der Heijden, M (2017).

Treatment and outcome after Immune checkpoint inhibitors (ICI) in; metastatic Urothelial Carcinoma (mUC): A European perspective

ANNALS OF ONCOLOGY. Meeting Abstract. 28.
Grivas, P, Plimack, E, Balar, AV, Castellano, D, O'Donnell, PH, Bellmunt, J, Powles, T, Hahn, N, de Wit, R, Bajorin, D, Ellison, MC, Frenkl, T, Keefe, SM, Vuky, J (2017).

Pembrolizumab (pembro) as first-line therapy in cisplatin-ineligible; advanced urothelial cancer (UC): Outcomes from KEYNOTE-052 in senior; patients (pts) with poor performance status

ANNALS OF ONCOLOGY. Meeting Abstract. 28.
Garcia-Donas, J, Lainez, N, Santos-Romero, M, Puente, J, Castellano, D, Rodriguez-Moreno, JF, Esteban, E, Pulido, EG, Parra, EMF, Lajusticia, LR, Domenech, M, Billalabeitia, EG, Saez, MI, Diaz, EG, Polo, SH, Herrador, A, Inglada-Perez, L, Robledo, M, Rodriguez-Antona, C (2017).

Prospective study assessing the expression of angiogenesis-related genes; as markers of anti-VEGFR2 response in advanced renal cell carcinoma

ANNALS OF ONCOLOGY. Meeting Abstract. 28.
Font, A, Real, FX, Puente, J, Mazon, FJV, Sala, N, Virizuela, JA, Rodriguez-Vida, A, Pulido, EG, Castellano, D, Climent, MA, Gallardo, E, del Alba, AG, Fernandez, PL, Jares, P, Aldecoa, I, Gibson, N, Serra, J, Imedio, ER, Ehrnrooth, E, Mellado, B (2017).

Afatinib in patients with advanced or metastatic urothelial carcinoma; (UC) with genetic alterations in ErbB receptors 1-3 who failed on; platinum-based chemotherapy: The Phase II LUX-Bladder 1 trial

ANNALS OF ONCOLOGY. Meeting Abstract. 28.
Medina, A, Montesa, A, Laorden, NR, Gonzalez-Billalabeitia, E, Rodriguez-Vida, A, Grau, G, Garces, T, Barrera, RM, Mazon, FJV, Villatoro, R, Baamonde, MAGD, Lopez, F, Polo, SH, Domenech, M, de Velasco, G, Borrega, P, Querol, R, Velez, E, Marcos, EC, Hidalgo, DO (2017).

PROSENZA: Prospective multi-centre study of prognostic factors in; castration resistant prostate cancer (CRPC) patients treated with; enzalutamide (ENZ)

ANNALS OF ONCOLOGY. Meeting Abstract. 28.
Diekstra MH, Belaustegui A, Swen JJ, Boven E, Castellano D, Gelderblom H, Mathijssen RH, García-Donas J, Rodríguez-Antona C, Rini BI, Guchelaar HJ (2017).

Sunitinib-induced hypertension in CYP3A4 rs4646437 A-allele carriers; with metastatic renal cell carcinoma

PHARMACOGENOMICS JOURNAL. Article. 17(1):42-46.
[doi:10.1038/tpj.2015.100]

2016

Park, SH, Castellano, D, Petrylak, DP, Galsky, MD, van der Heijden, MS, Loriot, Y, Ogawa, O, Su, WP, Huang, W, Levin, W, Ferro, S, Ben, Y, Bellmunt, J, Powles, T (2016).

DANUBE: A Phase 3 randomised study of first-line durvalumab (MEDI4736); +/- tremelimumab vs standard of care (SoC) chemotherapy (CT) in patients; (pts) with Stage IV urothelial carcinoma (UC)

ANNALS OF ONCOLOGY. Meeting Abstract. 27.
Dallavalle, C, Albino, D, Civenni, G, Merulla, J, Ostano, P, Mello-Grand, M, Rossi, S, Losa, M, D'Ambrosio, G, Sessa, F, Thalmann, GN, Garcia-Escudero, R, Zitella, A, Chiorino, G, Catapano, CV, Carbone, GM (2016).

MicroRNA-424 impairs ubiquitination to activate STAT3 and promote prostate tumor progression

JOURNAL OF CLINICAL INVESTIGATION. Article. 126(12):4585-4602.
[doi:10.1172/JCI86505]
Alameda, Josefa P., Navarro, Manuel, Ramirez, Angel, Page, Angustias, Suarez-Cabrera, Cristian, Moreno-Maldonado, Rodolfo, Paramio, Jesus M., del Carmen Farina, Maria, Del Rio, Marcela, Jesus Fernandez-Acenero, Maria, Bravo, Ana, de los Llanos Casanova, Maria (2016).

IKK alpha regulates the stratification and differentiation of the epidermis: implications for skin cancer development

Oncotarget. Article. 7(47):76779-76792.
[doi:10.18632/oncotarget.12527]
Costa C, Santos M, Martínez-Fernández M, Lorz C, Lázaro S, Paramio JM (2016).

Deregulation of the pRb-E2F4 axis alters epidermal homeostasis and favors tumor development

Oncotarget. Article. 7(46):75712-75728.
[doi:10.18632/oncotarget.12362]
Gargini R, Escoll M, García E, García-Escudero R, Wandosell F, Antón IM (2016).

WIP Drives Tumor Progression through YAP/TAZ-Dependent Autonomous Cell Growth

CELL REPORTS. Article. 17(8):1962-1977.
[doi:10.1016/j.celrep.2016.10.064]
Caro M, Font A, Comas S, Viciano M, Remon J, Céliz P, Robles J, Musulén E, Sendrós MJ, Mesalles E, Jiménez JA, Boix J, Arellano A, Fernández-Llamazares J (2016).

Preoperative low-dose weekly cisplatin and continuous infusion fluorouracil plus hyperfractionated radiotherapy in stage II-III esophageal carcinoma

CLINICAL & TRANSLATIONAL ONCOLOGY. Article. 18(11):1106-1113.
[doi:10.1007/s12094-016-1488-y]
De la Rosa Kehrmann F, García González L, Pamplona Casamayor M, Rodríguez Antolín A, Duarte Ojeda J, Villacampa Aubá F, Medina Polo J, González Monte E, Serrano A, Passas Martínez J (2016).

PROGRES EN UROLOGIE. Article. 26(13):713-713.
[doi:10.1016/j.purol.2016.07.094]
Duenas, M, Martinez, V, Lopez, F, Martinez, M, Rubio, C, Segovia, C, Teijeira, A, Villacampa, F, Vicente, A, Paramio, J (2016).

BMP-4 production by bladder cancer cells favors tumor progression and; promotes the development of a pro-tumoral immune environment

ANNALS OF ONCOLOGY. Meeting Abstract. 27.
Cascales Garcia, M. A., Colmenero, M., Rodriguez Antolin, A., Samper Ots, P. M., Valero, J., Gonzalez Sansegundo, C., Cabrera, J. A., Gomez Veiga, F., Couselo, M. L., Garcia Gomez, B., Hernando Arteche, A., Ponce Diaz-Reixa, J., Rubio, C., Rodriguez Cabrera, M., Martin-Arriscado, C., Lora, D., Paz-Ares, L. G., Cabeza Rodriguez, M. D. L. A. (2016).

Measuring Quality of Life in Low-Risk Prostate Cancer Treated With; Surgery, External Beam Radiation Therapy, or Brachytherapy. CAPCIRAB; Project: A Prospective, Multicentric Cohort Study

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS. Meeting Abstract. 96(2):277-277.
Tordella L, Khan S, Hohmeyer A, Banito A, Klotz S, Raguz S, Martin N, Dhamarlingam G, Carroll T, González Meljem JM, Deswal S, Martínez-Barbera JP, García-Escudero R, Zuber J, Zender L, Gil J (2016).

SWI/SNF regulates a transcriptional program that induces senescence to prevent liver cancer

GENES & DEVELOPMENT. Article. 30(19):2187-2198.
[doi:10.1101/gad.286112.116]
Grande, E, Perez, MPF, Font, A, Vazquez, S, Mellado, B, Calvo, OF, Vidal, MJM, Climent, MA, del Alba, AG, Gallardo, E, Sanchez, AR, Santander, C, Saez, MI, Duran, I, Puente, J, Gordoa, TA, Tudela, J, Martinez, A, Castellano, D, Billalabeitia, EG (2016).

Early responses to enzalutamide in AR-V7 positive first line metastatic; castration-resistant prostate cancer (mCRPC). A prospective SOGUG; clinical trial: The PREMIERE study

ANNALS OF ONCOLOGY. Meeting Abstract. 27.
[doi:10.1093/annonc/mdw372.10]
Anido, U, Fita, MJJ, Munielo-Romay, L, Perez-Valderrama, B, Mellado, B, de Olza, MO, Calvo, OF, Castellano, D, Parra, EMF, Domenec, M, Hernando, S, Arija, JA, Caballero, C, Duran, I, Campayo, M, Climent, MA (2016).

Phase II study of weekly cabazitaxel for 'unfit' metastatic castration; resistant prostate cancer patients (mCRPC) progressing after docetaxel; (D) treatment. Circulating tumour cell (CTC) analysis (SOGUG-CABASEM; Trial)

ANNALS OF ONCOLOGY. Meeting Abstract. 27.
[doi:10.1093/annonc/mdw372.37]
Capdevila, J., Teule, A., Barriuso, J., Castellano, D., Lopez, C., Manzano, J. L., Alonso, V., Garcia-Carbonero, R., Dotor, E., Matos, I., Custodio, A., Casanovas, O., Salazar, R. (2016).

Phase II study of everolimus (EVL) and octreotide (OCT) LAR in patients; with non-functioning gastrointestinal neuroendocrine tumours (GI-NETs):; EVERLAR study

ANNALS OF ONCOLOGY. Meeting Abstract. 27(6).
[doi:10.1093/annonc/mdw369.29]
Robles NR, Peces R, Gómez-Ferrer Á, Villacampa F, Álvarez-Ossorio JL, Pérez-Segura P, Morote J, Herrera-Imbroda B, Nieto J, Carballido J, Anido U, Valero M, Meseguer C, Torra R (2016).

Everolimus safety and efficacy for renal angiomyolipomas associated with tuberous sclerosis complex: a Spanish expanded access trial

ORPHANET JOURNAL OF RARE DISEASES. Article. 11(1):128-128.
[doi:10.1186/s13023-016-0517-9]
Chorny A, Casas-Recasens S, Sintes J, Shan M, Polentarutti N, García-Escudero R, Walland AC, Yeiser JR, Cassis L, Carrillo J, Puga I, Cunha C, Bastos H, Rodrigues F, Lacerda JF, Morais A, Dieguez-Gonzalez R, Heeger PS, Salvatori G, Carvalho A, Garcia-Sastre A, Blander JM, Mantovani A, Garlanda C, Cerutti A (2016).

The soluble pattern recognition receptor PTX3 links humoral innate and adaptive immune responses by helping marginal zone B cells

JOURNAL OF EXPERIMENTAL MEDICINE. Article. 213(10):2167-2185.
[doi:10.1084/jem.20150282]
Andradas C, Blasco-Benito S, Castillo-Lluva S, Dillenburg-Pilla P, Diez-Alarcia R, Juanes-García A, García-Taboada E, Hernando-Llorente R, Soriano J, Hamann S, Wenners A, Alkatout I, Klapper W, Rocken C, Bauer M, Arnold N, Quintanilla M, Megías D, Vicente-Manzanares M, Urigüen L, Gutkind JS, Guzmán M, Pérez-Gómez E, Sánchez C (2016).

Activation of the orphan receptor GPR55 by lysophosphatidylinositol promotes metastasis in triple-negative breast cancer.

Oncotarget. Article. 7(30):47565-47575.
[doi:10.18632/oncotarget.10206]
García-Donas J, Beuselinck B, Inglada-Pérez L, Graña O, Schöffski P, Wozniak A, Bechter O, Apellániz-Ruiz M, Leandro-García LJ, Esteban E, Castellano DE, González Del Alba A, Climent MA, Hernando S, Arranz JA, Morente M, Pisano DG, Robledo M, Rodriguez-Antona C (2016).

Deep sequencing reveals microRNAs predictive of antiangiogenic drug response

JCI insight. Article. 1(10).
[doi:10.1172/jci.insight.86051]
Gijón M, Bellusci M, Petraitiene B, Noguera-Julian A, Zilinskaite V, Sanchez Moreno P, Saavedra-Lozano J, Glikman D, Daskalaki M, Kaiser-Labusch P, Falup-Pecurariu O, Montagnani C, Prieto L, Gené A, Trumpulyte G, Kulecnikova I, Lepe JA, Cercenado E, Kudinsky R, Makri A, Huppertz HI, Bleotu L, Cocchi P, García-Hierro P, Vitkauskiene A, Fortuny C, Zukovskaja V, Neth O, Santos M, Rokney A, Petra M, Lixandru R, Galli L, Guillén S, Chaves F, Rojo Conejo P (2016).

Factors associated with severity in invasive community-acquired Staphylococcus aureus infections in children: a prospective European multicentre study

CLINICAL MICROBIOLOGY AND INFECTION. Article. 22(7).
[doi:10.1016/j.cmi.2016.04.004]
Jimenez-Ubieto, A., Garcia-Gigorro, R., Martinez-Sanchez, P., Rodriguez, A., Montejano, L., Grande, C. (2016).

ICU AND LONG-TERM MORTALITY ANALISIS OF HEMATOLOGOGICAL MALIGNANCIES ADMITTED IN ICU. A UNICENTRIC SEVEN YEARS REVIEW IN A SPANISH HOSPITAL

HAEMATOLOGICA. Meeting Abstract. 101(1):598-598.
Alameda JP, Gaspar M, Ramírez Á, Navarro M, Page A, Suárez-Cabrera C, Fernández MG, Mérida JR, Paramio JM, García-Fernández RA, Fernández-Aceñero MJ, Casanova ML (2016).

Deciphering the role of nuclear and cytoplasmic IKK beta in skin cancer

Oncotarget. Article. 7(20):29531-29547.
[doi:10.18632/oncotarget.8792]
Powles, Thomas, Lackner, Mark R., Oudard, Stephane, Escudier, Bernard, Ralph, Christy, Brown, Janet E., Hawkins, Robert E., Castellano, Daniel, Rini, Brian I., Staehler, Michael D., Ravaud, Alain, Lin, Wei, O'Keeffe, Bridget, Wang, Yulei, Lu, Shan, Spoerke, Jill M., Huw, Ling-Yuh, Byrtek, Michelle, Zhu, Rui, Ware, Joseph A., Motzer, Robert J. (2016).

Randomized Open-Label Phase II Trial of Apitolisib (GDC-0980), a Novel Inhibitor of the PI3K/Mammalian Target of Rapamycin Pathway, Versus Everolimus in Patients With Metastatic Renal Cell Carcinoma

JOURNAL OF CLINICAL ONCOLOGY. Article. 34(14):1660-204.
[doi:10.1200/JCO.2015.64.8808]
Rosenberg, Jonathan E., Hoffman-Censits, Jean, Powles, Tom, van der Heijden, Michiel S., Balar, Arjun V., Necchi, Andrea, Dawson, Nancy, O'Donnell, Peter H., Balmanoukian, Ani, Loriot, Yohann, Srinivas, Sandy, Retz, Margitta M., Grivas, Petros, Joseph, Richard W., Galsky, Matthew D., Fleming, Mark T., Petrylak, Daniel P., Perez-Gracia, Jose Luis, Burris, Howard A., Castellano, Daniel, Canil, Christina, Bellmunt, Joaquim, Bajorin, Dean, Nickles, Dorothee, Bourgon, Richard, Frampton, Garrett M., Cui, Na, Mariathasan, Sanjeev, Abidoye, Oyewale, Fine, Gregg D., Dreicer, Robert (2016).

Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: a single-arm, multicentre, phase 2 trial

LANCET. Article. 387(10031):1909-1920.
[doi:10.1016/S0140-6736(16)00561-4]
Gómez S, Prieto C, Vera C, R Otero J, Folgueira L (2016).

Evaluation of a new rapid diagnostic test for the detection of influenza and RSV

ENFERMEDADES INFECCIOSAS Y MICROBIOLOGIA CLINICA. Article. 34(5):298-302.
[doi:10.1016/j.eimc.2015.05.007]
Miñana B, Rodríguez-Antolín A, Gómez-Veiga F, Hernández C, Suárez JF, Fernández-Gómez JM, Unda M, Burgos J, Alcaraz A, Rodríguez P, Moreno C, Pedrosa E, Cózar JM, Grupo Español de Cáncer de Próstata (GESCAP) (2016).

Treatment trends for clinically localised prostate cancer. National population analysis: GESCAP group

ACTAS UROLOGICAS ESPANOLAS. Article. 40(4):209-216.
[doi:10.1016/j.acuro.2015.09.005]
Camps, C, Albanell, J, Anton, A, Aranda, E, Carrato, A, Cassinello, J, Castellano, D, Cruz, JJ, Garrido, P, Guillem, V, Gravalos, C, Lopez, G, Llorente, C, Lorenzo, A, Lluch, A, Ignacio, E, Diaz-Rubio, E (2016).

Quality Indicators to Assure and Improve Cancer Care in Spain Using the Delphi Technique

JOURNAL OF THE NATIONAL COMPREHENSIVE CANCER NETWORK. Article. 14(5):553-558.
[doi:10.6004/jnccn.2016.0063]
Robles, Nicolas R., Peces, Ramon, Gomez-Ferrer, Alvaro, Villacampa, Felipe, Alvarez-Ossorio, Jose L., Perez, Pedro, Trilla, Enrique, Herrera, Bernardo, Nieto, Javier, Carballido, Joaquin, Anido, Urbano, Meseguer, Cristina, Torra, Roser (2016).

THE EFFECT OF EVEROLIMUS IN PATIENTS WITH RENAL ANGIOMYOLIPOMA ASSOCIATED WITH TUBEROUS SCLEROSIS COMPLEX

NEPHROLOGY DIALYSIS TRANSPLANTATION. Meeting Abstract. 31(1):355-356.
Page, Angustias, Navarro, Manuel, Suarez-Cabrera, Cristian, Alameda, Josefa P., Casanova, M. Llanos, Paramio, Jesus M., Bravo, Ana, Ramirez, Angel (2016).

Protective role of p53 in skin cancer: Carcinogenesis studies in mice lacking epidermal p53

Oncotarget. Article. 7(15):20902-20918.
[doi:10.18632/oncotarget.7897]
Lalueza, Antonio, Ruiz, Sebastian, Villacampa, Felipe, Lopez, Rocio, Zabia, Elena, Sarandeses, Pilar, Cristina Hernandez, Ana, Maria Herrero, Juan, Lumbreras, Carlos (2016).

Recurrent Aortitis Associated With IgG4-Related Disease

CIRCULATION JOURNAL. Editorial Material. 80(4):1044-1044.
[doi:10.1253/circj.CJ-15-1186]
Perez-Valderrama, B., Arranz Arija, J. A., Rodriguez Sanchez, A., Pinto Marin, A., Borrega Garcia, P., Castellano Gaunas, D. E., Rubio Romero, G., Maximiano Alonso, C., Villa Guzman, J. C., Puertas Alvarez, J. L., Chirivella Gonzalez, I., Mendez Vidal, M. J., Juan Fita, M. J., Leon-Mateos, L., Lazaro Quintela, M., Garcia Dominguez, R., Jurado Garcia, J. M., Velez de Mendizabal, E., Lambea Sorrosal, J. J., Garcia Carbonero, I., Gonzalez del Alba, A., Suarez Rodriguez, C., Jimenez Gallego, P., Meana Garcia, J. A., Garcia Marrero, R. D., Gajate Borau, P., Santander Lobera, C., Molins Palau, C., Lopez Brea, M., Fernandez Parra, E. M., Reig Torras, O., Basterretxea Badiola, L., Vazquez Estevez, S., Gonzalez Larriba, J. L. (2016).

Validation of the International Metastatic Renal-Cell Carcinoma Database Consortium (IMDC) prognostic model for first-line pazopanib in metastatic renal carcinoma: the Spanish Oncologic Genitourinary Group (SOGUG) SPAZO study

ANNALS OF ONCOLOGY. Article. 27(4):706-711.
[doi:10.1093/annonc/mdv601]
Bozzini G, Provenzano M, Romero Otero J, Margreiter M, Garcia Cruz E, Osmolorskij B, Verze P, Pavan N, Sanguedolce F, Buffi N, Guazzoni G, Taverna G (2016).

Role of Penile Doppler US in the Preoperative Assessment of Penile Squamous Cell Carcinoma Patients: Results From a Large Prospective Multicenter European Study

UROLOGY. Article. 90:131-135.
[doi:10.1016/j.urology.2016.01.003]
Romero-Otero, Javier, Garcia-Gomez, Borja, Duarte-Ojeda, Jose M., Rodriguez-Antolin, Alfredo, Vilaseca, Antoni, Carlsson, Sigrid V., Touijer, Karim A. (2016).

Active surveillance for prostate cancer

INTERNATIONAL JOURNAL OF UROLOGY. Review. 23(3):211-218.
[doi:10.1111/iju.13016]
Lainez, Nuria, Garcia-Donas, Jesus, Esteban, Emilio, Puente, Javier, Isabel Saez, M., Gallardo, Enrique, Pinto-Marin, Alvaro, Vazquez-Estevez, Sergio, Leon, Luis, Garcia-Carbonero, Icar, Suarez-Rodriguez, Cristina, Molins, Carmen, Climent-Duran, Miguel A., Lazaro-Quintela, Martin, Gonzalez del Alba, Aranzazu, Jose Mendez-Vidal, Maria, Chirivella, Isabel, Afonso, Francisco J., Lopez-Brea, Marta, Sala-Gonzalez, Nuria, Domenech, Montserrat, Basterretxea, Laura, Santander-Lobera, Carmen, Gil-Arnaiz, Irene, Fernandez, Ovidio, Caballero-Diaz, Cristina, Mellado, Begona, Marrupe, David, Garcia-Sanchez, Jose, Sanchez-Escribano, Ricardo, Fernandez Parra, Eva, Villa Guzman, Jose C., Martinez-Ortega, Esther, Belen Gonzalez, Maria, Moran, Marina, Suarez-Paniagua, Beatriz, Lecumberri, Maria J., Castellano, Daniel (2016).

Impact on clinical practice of the implementation of guidelines for the toxicity management of targeted therapies in kidney cancer. The protect-2 study

BMC CANCER. Article. 16(1):135-135.
[doi:10.1186/s12885-016-2084-9]
Diekstra, M. H., Belaustegui, A., Swen, J. J., Boven, E., Castellano, D., Gelderblom, H., Mathijssen, R. H., Garcia-Donas, J., Rodriguez-Antona, C., Rini, B. I., Guchelaar, H. (2016).

SUNITINIB-INDUCED HYPERTENSION IN CYP3A4 RS4646437 A-ALLELE CARRIERS WITH METASTATIC RENAL CELL CARCINOMA.

CLINICAL PHARMACOLOGY & THERAPEUTICS. Meeting Abstract. 99(1):10-11.
Diekstra, M. H., Belaustegui, A., Swen, J. J., Boven, E., Castellano, D., Gelderblom, H., Mathijssen, R. H., Garcia-Donas, J., Rodriguez-Antona, C., Rini, B. I., Guchelaar, H. (2016).

SUNITINIB-INDUCED HYPERTENSION IN CYP3A4 RS4646437 A-ALLELE CARRIERS WITH METASTATIC RENAL CELL CARCINOMA.

CLINICAL PHARMACOLOGY & THERAPEUTICS. Meeting Abstract. 99(1):24-24.
Liu, X., Diekstra, M. H., Swen, J. J., Boven, E., Castellano, D., Gelderblom, H., Mathijssen, R. H., Rodriguez-Antona, C., Garcia-Donas, J., Rini, B. I., Guchelaar, H. (2016).

ASSOCIATION OF SINGLE NUCLEOTIDE POLYMORPHISMS IN IL8 AND IL13 WITH SUNITINIB-INDUCED TOXICITY IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA.

CLINICAL PHARMACOLOGY & THERAPEUTICS. Meeting Abstract. 99(1):84-84.
Liu, X., Diekstra, M. H., Swen, J. J., Boven, E., Castellano, D., Gelderblom, H., Mathijssen, R. H., Rodriguez-Antona, C., Garcia-Donas, J., Rini, B. I., Guchelaar, H. (2016).

ASSOCIATION OF SINGLE NUCLEOTIDE POLYMORPHISMS IN IL8 AND IL13 WITH SUNITINIB-INDUCED TOXICITY IN PATIENTS WITHMETASTATIC RENAL CELL CARCINOMA.

CLINICAL PHARMACOLOGY & THERAPEUTICS. Meeting Abstract. 99(1):6-7.
Raymond, Eric, Niccoli, Patricia, Castellano, Daniel, Valle, Juan W., Hammel, Pascal, Raoul, Jean-Luc, Vinik, Aaron, Bang, Yung-Jue, Lee, Se-Hoon, Borbath, Ivan, Bohas, Catherine Lombard, Metrakos, Peter, Smith, Denis Michel, Chen, Jen-Shi, Seitz, Jean Francois, Patyna, Shem, Huang, Xin, Ishak, Jack, Faivre, Sandrine J., Ruszniewski, Philippe B. (2016).

Sunitinib (SU) in patients with advanced, progressive pancreatic neuroendocrine tumors (pNET): Final overall survival (OS) results from a phase III randomized study including adjustment for crossover

JOURNAL OF CLINICAL ONCOLOGY. Meeting Abstract. 34(4, S).
[doi:10.1200/jco.2016.34.4_suppl.309]
Grande, Enrique, Castellano, Daniel E., Custodio, Ana B., Garcia-Carbonero, Rocio, Gonzalez, Encarnacion, Lopez-Lopez, Carlos, Munarriz, Javier, Sevilla, Isabel, Teule, Alexandre, Vinuales, Marta Benavent, Alonso, Teresa, Borau, Pablo Gajate, Palacios, Jose, Capdevila, Jaume (2016).

A phase II trial to assess the activity and safety of the hypoxia-activated prodrug evofosfamide (TH-302) in combination with sunitinib in patients with disseminated grade 1 and 2 pancreatic neuroendocrine tumors (pNET) as a first-line approach: The GETNE-1408 trial.

JOURNAL OF CLINICAL ONCOLOGY. Meeting Abstract. 34(4, S).
[doi:10.1200/jco.2016.34.4_suppl.tps479]
Raymond, E., Niccoli, P., Castellano, D., Valle, J., Hammel, P., Raoul, J. L., Vinik, A., Bang, Y. J., Lee, S. H., Borbath, I, Lombard-Bohas, C., Metrakos, P., Smith, D. M., Chen, J., Seitz, J. S., Patyna, S., Lu, D. R., Ishak, J., Faivre, S., Ruszniewski, P. (2016).

Sunitinib (SU) in Patients with Advanced, Progressive Pancreatic Neuroendocrine Tumors (pNET): Final Overall Survival (OS) Results from a Phase III Randomized Study Including Adjustment for Crossover

NEUROENDOCRINOLOGY. Meeting Abstract. 103(1):84-84.
Jimenez-Fonseca, P., Capdevila, J., Alonso Orduna, V, Fernandez Medina, I, Teule Vega, A., Marazuela Azpiroz, M., Beguiristain Gomez, A., Llanos Munoz, M., Martinez del Prado, M., Sevilla Garcia, M., Carmona-Bayonas, A., Castellano, D., Diaz Perez, J., Castano, A., Garcia Carbonero, R. (2016).

Epidemiology, Pathological Features and Clinical Outcome of Gastroenteropancreatic Neuroendocrine Neoplasms (GEP-NENs): Results from the National Neuroendocrine Cancer Registry of Spain (R-GETNE)

NEUROENDOCRINOLOGY. Meeting Abstract. 103(1):17-17.
Manneh R, Castellano D, Caso O, Loinaz C, Jiménez J, Estenoz J, Calatayud M, Sepúlveda JM, García-Carbonero R (2016).

Well-Differentiated Grade 2, Type 3 Gastrointestinal Neuroendocrine Tumour with Bilateral Metastatic Ovarian Involvement: Report of an Unusual Case

Case reports in oncology. Article. 9(1):255-261.
[doi:10.1159/000445940]
Martínez-Fernández M, Paramio JM, Dueñas M (2016).

RNA Detection in Urine From RNA Extraction to Good Normalizer Molecules

JOURNAL OF MOLECULAR DIAGNOSTICS. Article. 18(1):15-22.
[doi:10.1016/j.jmoldx.2015.07.008]

2015

Martinez-Fernandez, Monica, Duenas, Marta, Feber, Andrew, Segovia, Cristina, Garcia-Escudero, Ramon, Rubio, Carolina, Lopez-Calderon, Fernando F., Diaz-Garcia, Claudio, Villacampa, Felipe, Duarte, Jose, Gomez-Rodriguez, Maria J., Castellano, Daniel, Rodriguez-Peralto, Jose L., de la Rosa, Federico, Beck, Stephan, Paramio, Jesus M. (2015).

A Polycomb-mir200 loop regulates clinical outcome in bladder cancer

Oncotarget. Article. 6(39):42258-42275.
[doi:10.18632/oncotarget.5546]
Bozzini, G., Albersen, M., Romero Otero, J., Margreiter, M., Garcia Cruz, E., Mueller, A., Gratzke, C., Serefoglu, E. C., Martinez Salamanca, J. I., Verze, P. (2015).

Feasibility and safety of conservative surgery for the treatment of spermatic cord leiomyosarcoma

INTERNATIONAL JOURNAL OF SURGERY. Article. 24(A):81-84.
[doi:10.1016/j.ijsu.2015.11.012]
Diekstra MH, Liu X, Swen JJ, Boven E, Castellano D, Gelderblom H, Mathijssen RH, Rodríguez-Antona C, García-Donas J, Rini BI, Guchelaar HJ (2015).

Association of single nucleotide polymorphisms in IL8 and IL13 with sunitinib-induced toxicity in patients with metastatic renal cell carcinoma

EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY. Article. 71(12):1477-1484.
[doi:10.1007/s00228-015-1935-7]
Motzer, Robert J., Escudier, Bernard, Mcdermott, David F., George, Saby, Hammers, Hans J., Srinivas, Sandhya, Tykodi, Scott S., Sosman, Jeffrey A., Procopio, Giuseppe, Plimack, Elizabeth R., Castellano, Daniel, Gurney, Howard, Donskov, Frede, Bono, Petri, Wagstaff, John, Gauler, Thomas C., Ueda, Takeshi, Xu, Li-An, Waxman, Ian M., Sharma, Padmanee, Checkmate 025 Invest (2015).

CheckMate 025: a randomized, open-label, phase Ill study of nivolumab versus everolimus in advanced renal cell carcinoma (RCC)

BJU INTERNATIONAL. Meeting Abstract. 116(5, SI):17-17.
Motzer, R. J., Escudier, B., McDermott, D. F., George, S., Hammers, H. J., Srinivas, S., Tykodi, S. S., Sosman, J. A., Procopio, G., Plimack, E. R., Castellano, D., Choueiri, T. K., Gurney, H., Donskov, F., Bono, P., Wagstaff, J., Gauler, T. C., Ueda, T., Tomita, Y., Schutz, F. A., Kollmannsberger, C., Larkin, J., Ravaud, A., Simon, J. S., Xu, L-A, Waxman, I. M., Sharma, P., CheckMate 025 Investigators (2015).

Nivolumab versus Everolimus in Advanced Renal-Cell Carcinoma

NEW ENGLAND JOURNAL OF MEDICINE. Article. 373(19):1803-1813.
[doi:10.1056/NEJMoa1510665]
Herranz Amo F, Hernández Fernández C, Cózar Olmo JM, Miñana López B, Gómez-Veiga F, Rodríguez-Antolín A, Pedrosa E, Grupo Español de Cáncer de Próstata (GESCAP) (2015).

Adherence to the lymphadenectomy recommendations of the 2009 clinical guidelines in the 2010 National Prostate Cancer Registry

ACTAS UROLOGICAS ESPANOLAS. Article. 39(9):546-552.
[doi:10.1016/j.acuro.2015.05.004]
Martínez-Fernández M, Rubio C, Segovia C, López-Calderón FF, Dueñas M, Paramio JM (2015).

EZH2 in Bladder Cancer, a Promising Therapeutic Target

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 16(11):27107-27132.
[doi:10.3390/ijms161126000]
De La Rosa Kehrmann F, García González L, González Monte E, Rodríguez Antolín A, Pamplona Casamayor M, Duarte Ojeda J, Tejido Sánchez Á, Villacampa Aubá F, Passas Martínez J (2015).

[Not Available].

PROGRES EN UROLOGIE. Article. 25(13):722-722.
[doi:10.1016/j.purol.2015.08.013]
Martinez-Fernandez, Monica, Feber, Andrew, Duenas, Marta, Segovia, Cristina, Rubio, Carolina, Fernandez, Maria, Villacampa, Felipe, Duarte, Jose, Lopez-Calderon, Fernando F., Jose Gomez-Rodriguez, Ma, Castellano, Daniel, Rodriguez-Peralto, Jose L., de la Rosa, Federico, Beck, Stephan, Paramio, Jesus M. (2015).

Analysis of the Polycomb-related lncRNAs HOTAIR and ANRIL in bladder cancer

Clinical epigenetics. Article. 7:109-109.
[doi:10.1186/s13148-015-0141-x]
Diekstra MH, Swen JJ, Boven E, Castellano D, Gelderblom H, Mathijssen RH, Rodríguez-Antona C, García-Donas J, Rini BI, Guchelaar HJ (2015).

CYP3A5 and ABCB1 Polymorphisms as Predictors for Sunitinib Outcome in Metastatic Renal Cell Carcinoma

EUROPEAN UROLOGY. Article. 68(4):621-629.
[doi:10.1016/j.eururo.2015.04.018]
Garcia Sanz, R., Sureda, A., Gonzalez, A. P., Salar, A., Rodriguez, A., De La Cruz, F., Domiingo-Domenech, E., Canales, M., Lopez, J., Moreno, M., Rodriguez, G., Jose Luis, P., Rodriguez, M. J., Lopez-Guillermo, A., Caballero, M. D., Jimenez, S., Martinez, C. (2015).

EVALUATION OF THE BRENUTXIMAB VEDOTIN REGIME AND ESHAP (BRESHAP) IN LYMPHOMA PRIMARY RESISTANT HODGKIN'S OR IN FIRST RELAPSE: RESULTS PRELIMINARY A TRIAL PHASE I-II OF THE SPANISH GROUP OF LYMPHOMAS AND TRANSPLANTATION OF BONE MARROW (GELTAMO)

HAEMATOLOGICA. Meeting Abstract. 100(4):9-9.
Grande, E., Capdevila, J., Castellano, D., Teule, A., Duran, I., Fuster, J., Sevilla, I., Escudero, P., Sastre, J., Garcia-Donas, J., Casanovas, O., Earl, J., Ortega, L., Apellaniz-Ruiz, M., Rodriguez-Antona, C., Alonso-Gordoa, T., Diez, J. J., Carrato, A., Garcia-Carbonero, R. (2015).

Pazopanib in pretreated advanced neuroendocrine tumors: a phase II, open-label trial of the Spanish Task Force Group for Neuroendocrine Tumors (GETNE)(aEuro)

ANNALS OF ONCOLOGY. Article. 26(9):1987-1993.
[doi:10.1093/annonc/mdv252]
Miranda-Utrera N, Medina-Polo J, Pamplona-Casamayor M, Passas-Martínez JB, Rodríguez-Antolín A, de la Rosa Kehrmann F, Duarte-Ojeda JM, Tejido-Sánchez A, Villacampa Aubá F, Andrés Belmonte A (2015).

Uncontrolled non-heartbeating donors (types I-II) with normothermic recirculation vs. heartbeating donors: Evaluation of functional results and survival

ACTAS UROLOGICAS ESPANOLAS. Article. 39(7):429-434.
[doi:10.1016/j.acuro.2015.01.005]
Capdevila, Jaume, Sevilla, Isabel, Alonso, Vicente, Anton Aparicio, Luis, Jimenez Fonseca, Paula, Grande, Enrique, Jose Reina, Juan, Luis Manzano, Jose, Alonso Lajara, Juan Domingo, Barriuso, Jorge, Castellano, Daniel, Medina, Javier, Lopez, Carlos, Segura, Angel, Carrera, Sergio, Crespo, Guillermo, Fuster, Jose, Munarriz, Javier, Garcia Alfonso, Pilar (2015).

Evaluation of the efficacy and safety of lanreotide in combination with targeted therapies in patients with neuroendocrine tumours in clinical practice: a retrospective cross-sectional analysis

BMC CANCER. Article. 15:495-495.
[doi:10.1186/s12885-015-1512-6]
Jimenez-Alcaide, Estibaliz, Medina-Polo, Jose, Garcia-Gonzalez, Lucia, Arrebola-Pajares, Ana, Guerrero-Ramos, Felix, Perez-Cadavid, Santiago, Sopena-Sutil, Raquel, Benitez-Sala, Rauf, Alonso-Isa, Manuel, Lara-Isla, Alba, Bautista Passas-Martinez, Juan, Tejido-Sanchez, Angel (2015).

Healthcare-associated urinary tract infections in patients with a urinary catheter: Risk factors, microbiological characteristics and patterns of antibiotic resistance.

ARCHIVOS ESPANOLES DE UROLOGIA. Article. 68(6):541-550.
Gore, M. E., Szczylik, C., Porta, C., Bracarda, S., Bjarnason, G. A., Oudard, S., Lee, S-H, Haanen, J., Castellano, D., Vrdoljak, E., Schoeffski, P., Mainwaring, P., Hawkins, R. E., Crino, L., Kim, T. M., Carteni, G., Eberhardt, W. E. E., Zhang, K., Fly, K., Matczak, E., Lechuga, M. J., Hariharan, S., Bukowski, R. (2015).

Final results from the large sunitinib global expanded-access trial in metastatic renal cell carcinoma

BRITISH JOURNAL OF CANCER. Article. 113(1):12-19.
[doi:10.1038/bjc.2015.196]
Sepulveda-Sanchez, Juan, Ramos, Ana, Hilario, Amaya, De Velascoi, Guillermo, Castellano, Daniel, Garcia De La Torre, Marta, Rodon, Jordi, Lahn, Michael F. (2015).

Brain perfusion and permeability in patients with advanced, refractory glioblastoma treated with lomustine and the transforming growth factor-beta receptor I kinase inhibitor LY2157299 monohydrate

ONCOLOGY LETTERS. Article. 9(6):2442-2448.
[doi:10.3892/ol.2015.3106]
Perez-Gomez, Eduardo, Andradas, Clara, Blasco-Benito, Sandra, Caffarel, Maria M., Garcia-Taboada, Elena, Villa-Morales, Maria, Moreno, Estefania, Hamann, Sigrid, Martin-Villar, Ester, Flores, Juana M., Wenners, Antonia, Alkatout, Ibrahim, Klapper, Wolfram, Roecken, Christoph, Bronsert, Peter, Stickeler, Elmar, Staebler, Annette, Bauer, Maret, Arnold, Norbert, Soriano, Joaquim, Perez-Martinez, Manuel, Megias, Diego, Moreno-Bueno, Gema, Ortega-Gutierrez, Silvia, Artola, Marta, Vazquez-Villa, Henar, Quintanilla, Miguel, Fernandez-Piqueras, Jose, Canela, Enric I., McCormick, Peter J., Guzman, Manuel, Sanchez, Cristina (2015).

Role of Cannabinoid Receptor CB2 in HER2 Pro-oncogenic Signaling in Breast Cancer

JNCI-JOURNAL OF THE NATIONAL CANCER INSTITUTE. Article. 107(6).
[doi:10.1093/jnci/djv077]
Romero-Otero J, Medina-Polo J, García-Gómez B, Lora-Pablos D, Duarte-Ojeda JM, García-González L, García-Cruz E, Rodríguez-Antolín A (2015).

Semen Quality Assessment in Fertile Men in Madrid During the Last 3 Decades

UROLOGY. Article. 85(6):1333-1338.
[doi:10.1016/j.urology.2015.02.001]
Kalathur M, Toso A, Chen J, Revandkar A, Danzer-Baltzer C, Guccini I, Alajati A, Sarti M, Pinton S, Brambilla L, Di Mitri D, Carbone G, Garcia-Escudero R, Padova A, Magnoni L, Tarditi A, Maccari L, Malusa F, Kalathur RK, A Pinna L, Cozza G, Ruzzene M, Delaleu N, Catapano CV, Frew IJ, Alimonti A (2015).

A chemogenomic screening identifies CK2 as a target for pro-senescence therapy in PTEN-deficient tumours

NATURE COMMUNICATIONS. Article. 6:7227-7227.
[doi:10.1038/ncomms8227]
Zur, Rafal, Garcia-Ibanez, Laura, Nunez-Buiza, Angel, Aparicio, Noelia, Liappas, Georgios, Escos, Alejandra, Risco, Ana, Page, Angustias, Saiz-Ladera, Cristina, Alsina-Beauchamp, Dayanira, Montans, Jose, Paramio, Jesus M., Cuenda, Ana (2015).

Combined deletion of p38 gamma and p38 delta reduces skin inflammation and protects from carcinogenesis

Oncotarget. Article. 6(15):12920-12935.
[doi:10.18632/oncotarget.4320]
Palla, Adelaida R., Piazzolla, Daniela, Alcazar, Noelia, Canamero, Marta, Grana, Osvaldo, Gomez-Lopez, Gonzalo, Dominguez, Orlando, Duenas, Marta, Paramio, Jesus M., Serrano, Manuel (2015).

The pluripotency factor NANOG promotes the formation of squamous cell carcinomas

SCIENTIFIC REPORTS. Article. 5:10205-10205.
[doi:10.1038/srep10205]
Marin-Ramos, Nagore I., Alonso, Dulce, Ortega-Gutierrez, Silvia, Ortega-Nogales, Francisco J., Balabasquer, Moises, Vazquez-Villa, Henay, Andradas, Clara, Blasco-Benito, Sandra, Perez-Gomez, Eduardo, Canales, Angeles, Jimenez-Barbero, Jesus, Marquina, Ana, Moscoso del Prado, Jaime, Sanchez, Cristina, Martin-Fontecha, Mar, Lopez-Rodriguez, Maria L. (2015).

New Inhibitors of Angiogenesis with Antitumor Activity in Vivo

JOURNAL OF MEDICINAL CHEMISTRY. Article. 58(9):3757-3766.
[doi:10.1021/jm5019252]
Garcia Cruz, E., Martinez-Salamanca, J., Romero Otero, J. (2015).

ERECTILE DYSFUNCTION CORRELATES WITH METS IN MEN WITH MODERATE PROSTATIC SYMPTOMS

The journal of sexual medicine. Meeting Abstract. 12(3, SI):235-235.
Garcia Cruz, E., Martinez-Salamanca, I, J., Javier, R. (2015).

ERECTILE DYSFUNCTION AND AGING SYMPTOMS ARE RELATED TO A HIGHER CHARLSON COMORBIDITY INDEX

The journal of sexual medicine. Meeting Abstract. 12(3, SI):235-236.
Garcia Gonzalez, L., Romero Otero, J., Sopena Sutil, R., Jimenez Alcaide, E., Garcia Gomez, B., Duarte Ojeda, J. M., Rodriguez Antolin, A., Romero Otero, J. (2015).

PROSPECTIVE EVALUATION OF THE EARLY IMPACT OF THE LHRH ANALOGUES IN THE TREATMENT OF PROSTATE CANCER IN SEXUAL, PSYCHO-COGNITIVE, EMOTIONAL AND QUALITY OF LIFE PARAMETERS

The journal of sexual medicine. Meeting Abstract. 12(3, SI):238-238.
Garcia Gomez, B., Romero Otero, J., Medina Polo, J., Garcia Gonzalez, L., Jimenez Alcaide, F., Rodriguez Antolin, A., Passas Martinez, J. (2015).

CRITICAL EVALUATION OF PEYRONIE'S DISEASE (PD) TREATMENT WITH PLAQUE EXCISION AND GRAFTING OF THE TUNICAL DEFECT WITH LYOPHILIZED BOVINE PERICARDIUM

The journal of sexual medicine. Meeting Abstract. 12(3, SI):247-247.
Medina-Polo, J., Javier, R. -O, Garcia-Gomez, B., David, L. -P, Jimenez-Alcaide, E., Garcia-Gonzalez, L., Arrebola-Pajares, A., Rodriguez-Antolin, A., Garcia Cruz, E. (2015).

SEMEN QUALITY ASSESSMENT IN FERTILE MEN IN SPAIN DURING THE LAST THREE DECADES

The journal of sexual medicine. Meeting Abstract. 12(3, SI):253-254.
Alajati, Abdullah, Guccini, Ilaria, Pinton, Sandra, Garcia-Escudero, Ramon, Bernasocchi, Tiziano, Sarti, Manuela, Montani, Erica, Rinaldi, Andrea, Montemurro, Filippo, Catapano, Carlo, Bertoni, Francesco, Alimonti, Andrea (2015).

Interaction of CDCP1 with HER2 Enhances HER2-Driven Tumorigenesis and Promotes Trastuzumab Resistance in Breast Cancer

CELL REPORTS. Article. 11(4):564-576.
[doi:10.1016/j.celrep.2015.03.044]
Tome-Amat, Jaime, Olombrada, Miriam, Ruiz-de-la-Herran, Javier, Perez-Gomez, Eduardo, Andradas, Clara, Sanchez, Cristina, Martinez, Leopoldo, Martinez-del-Pozo, Alvaro, Gavilanes, Jose G., Lacadena, Javier (2015).

Efficient in vivo antitumor effect of an immunotoxin based on ribotoxin alpha-sarcin in nude mice bearing human colorectal cancer xenografts

Springerplus. Article. 4:168-168.
[doi:10.1186/s40064-015-0943-5]
de Velasco, Guillermo, Munoz, Cesar, Sepulveda, Juan M., Castellano, Daniel (2015).

Sequential treatments in hereditary leiomyomatosis and renal cell carcinoma (HLRCC): Case report and review of the literature

CUAJ-CANADIAN UROLOGICAL ASSOCIATION JOURNAL. Article. 9(3-4):243-246.
[doi:10.5489/cuaj.2264]
Contreras-Jurado C, Lorz C, García-Serrano L, Paramio JM, Aranda A (2015).

Thyroid hormone signaling controls hair follicle stem cell function

MOLECULAR BIOLOGY OF THE CELL. Article. 26(7):1263-1272.
[doi:10.1091/mbc.E14-07-1251]
Guillem, Vicente, Angel Climent, Miguel, Cassinello, Javier, Esteban, Emilio, Castellano, Daniel, Luis Gonzalez-Larriba, Jose, Maroto, Pablo, Camps, Carlos (2015).

Controversies in the treatment of invasive urothelial carcinoma: a case report and review of the literature

BMC UROLOGY. Article. 15(1):15-15.
[doi:10.1186/s12894-015-0008-7]
Morales P, Blasco-Benito S, Andradas C, Gómez-Cañas M, Flores JM, Goya P, Fernández-Ruiz J, Sánchez C, Jagerovic N (2015).

Selective, Nontoxic CB2 Cannabinoid o-Quinone with in Vivo Activity against Triple-Negative Breast Cancer

JOURNAL OF MEDICINAL CHEMISTRY. Article. 58(5):2256-2264.
[doi:10.1021/acs.jmedchem.5b00078]
Fernandez Calvo, Ovidio, Fernandez Parra, Eva, Perez-Valderrama, Begona, Mellado, Begona, Ochoa de Olza, Maria, Castellano, Daniel E., Domenech, Montserrat, Hernando Polo, Susana, Anido, Urbano, Arranz Arija, Jose Angel, Caballero, Cristina, Jose Juan, M., Duran, Ignacio, Campayo, Marc, Serrano, Monica, Angel Climent, Miguel (2015).

Weekly cabazitaxel in ``unfit'' metastatic castration-resistant prostate cancer patients (mCRPC) progressing after docetaxel (D) treatment: Preliminary results of CABASEM-SOGUG phase II trial.

JOURNAL OF CLINICAL ONCOLOGY. Meeting Abstract. 33(7, S).
Maraver, Antonio, Fernandez-Marcos, Pablo J., Cash, Timothy P., Mendez-Pertuz, Marinela, Duenas, Marta, Maietta, Paolo, Martinelli, Paola, Munoz-Martin, Maribel, Martinez-Fernandez, Monica, Canamero, Marta, Roncador, Giovanna, Martinez-Torrecuadrada, Jorge L., Grivas, Dimitrios, Luis de la Pompa, Jose, Valencia, Alfonso, Paramio, Jesus M., Real, Francisco X., Serrano, Manuel (2015).

NOTCH pathway inactivation promotes bladder cancer progression

JOURNAL OF CLINICAL INVESTIGATION. Article. 125(2):824-830.
[doi:10.1172/JCI78185]
Diekstra, M., Swen, J. J., Boven, E., Castellano, D., Ganapathi, R., Gelderblom, H., Mathijssen, R. H., Rodriguez-Antona, C., Garcia-Donas, J., Rini, B., Guchelaar, H. (2015).

A MULTICENTER VALIDATION STUDY OF GENETIC POLYMORPHISMS ASSOCIATED WITH TOXICITY AND EFFICACY OF SUNITINIB IN PATIENTS WITH METASTATIC RENAL CELL CARCINOMA.

CLINICAL PHARMACOLOGY & THERAPEUTICS. Meeting Abstract. 97(1):13-13.
Velasco G, Sánchez C, Guzmán M (2015).

Endocannabinoids and Cancer.

Handbook of experimental pharmacology. Article. 231:449-472.
[doi:10.1007/978-3-319-20825-1_16]

Alameda, JP, Navarro M, Ramírez Á, Page A, Suárez-Cabrera C, Moreno-Maldonado R, Paramio JM, Fariña MD, Del Río M, Fernández-Aceñero MJ, Bravo A, Casanova ML ().

IKKa regulates the stratification and differentiation of the epidermis: implications for skin cancer development.

Oncotarget. Article.
Palma, C, Patricia, PM, Lezana, JM, Cruz, J, Quesada, JF, Vila, S, Alvarez-Mora, I, Arteche-Lopez, A, Gomez-Manjon, I, Sanchez, MT, Gomez-Rodriguez, MJ, Sanchez, J, Moreno-Garcia, M ().

A Novel Pathogenic Variant in the MN1 Gene in a Patient Presenting with Rhombencephalosynapsis and Craniofacial Anomalies, Expanding MN1 C-terminal Truncation Syndrome

Journal of Pediatric Genetics. Article.
[doi:10.1055/s-0041-1728650]
Gaya JM, Territo A, Woldu S, Schwartzmann I, Verri P, González-Pérez L, Cózar JM, Miñana B, Medina RA, de la Rosa-Kehrmann F, Lozano-Palacio F, Ribal MJ, Hernández C, Castiñeiras JJ, Requena MJ, Moreno J, Caraballido JA, Baena V, Breda A, Palou Redorta J ().

Incidental diagnosis of bladder cancer in a national observational study in spain.

Actas Urologicas Espanolas. Article.
[doi:10.1016/j.acuroe.2022.09.005]
Guerrero-Ramos F ().

BCG unresponsive non-muscle invasive bladder cancer: The beginning of a new era?

Actas Urologicas Espanolas. Editorial Material.
[doi:10.1016/j.acuroe.2023.01.009]