MODEL OF COGNITIVE DEFICIT ANIMAL, PROCEDURES AND APPLICATIONS
Model of cognitive deficit animal that presents absence of megalin specifically in the endothelium of the cerebral capillaries, as well as its procedure of obtaining and use as a model of neurodegenerative diseases, more specifically Alzheimer’s.
Aplications:
- Identification of useful compounds for the treatment of these diseases.
- Identification and evaluation of therapeutic compounds against a degenerative disease.
- Try new drugs, pharmacological development treatments, side effects thereof and aspects related to preclinical trials.