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Translational Research in Hypertension and Cardiorenal Disease

Publications

2026

Heerspink, HJL, Agarwal, R, Amor, AJ, Bech, JN, Cherney, DZ, Fiorina, P, Rossing, P, Schousboe, K, Selby, NM, Anker, SD, Filippatos, G, Pitt, B, Ruilope, LM, Lawatscheck, R, Brinker, M, Russell, J, Schloemer, P, Mcgill, JB (2026).

Comparing CKD populations with T1D and T2D: a perspective based on the FINE-ONE and FIDELITY populations

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 41(3):556-565.
[doi:10.1093/ndt/gfaf183]
Ostrominski, JW, Filippatos, G, Claggett, BL, Miao, ZM, Desai, AS, Jhund, PS, Henderson, A, Rohwedder, K, Brinker, MD, Scalise, A, Schloemer, P, Lam, CSP, Senni, M, Shah, SJ, Voors, AA, Zannad, F, Rossing, P, Ruilope, LM, Anker, SD, Pitt, B, Agarwal, R, McMurray, JJV, Solomon, SD, Vaduganathan, M (2026).

Effect of Finerenone on Morbidity and Mortality in CKD

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Article. 37(2):312-325.
[doi:10.1681/ASN.0000000823]
Katayama, S, Anker, SD, Zhu, DL, Kim, S, Wu, MJ, Kawanami, D, Rossing, P, Ruilope, LM, Ahlers, C, Brinker, M, Mann, A, Tian, YJ, Yamashita, S, Pitt, B (2026).

Efficacy and safety of finerenone in Asian patients with type 2 diabetes and chronic kidney disease: A FIDELITY analysis by baseline kidney function

JOURNAL OF DIABETES AND ITS COMPLICATIONS. Article. 40(1).
[doi:10.1016/j.jdiacomp.2025.109213]

2025

del Olmo, PDD, Herraiz, I, Villalaín, C, de la Parte, B, Rodríguez-Sánchez, E, Ruiz-Hurtado, G, Fernández-Friera, L, Morales, E, Ayala, JL, Solís, J, Galindo, A (2025).

Cardiovascular disease in women with early-onset preeclampsia: a matched case-control study

Journal of Maternal-Fetal & Neonatal Medicine. Article. 38(1).
[doi:10.1080/14767058.2025.2459302]
de la Sierra, A, Vinyoles, E, Gorostidi, M, Segura, J, Ruilope, LM (2025).

Impact of Office and Ambulatory Blood Pressure on Mortality in Patients with Coronary Heart Disease

Cardiology and Therapy. Article. 14(4):635-649.
[doi:10.1007/s40119-025-00437-1]
Gorostidi, M, Böhm, M, Ruilope, LM, Staplin, N, Vinyoles, E, Segura, J, Williams, B, de la Sierra, A (2025).

Mortality according to ambulatory blood pressure in hypertensive patients with normal or impaired kidney function

HYPERTENSION RESEARCH. Article. 48(12):3234-3243.
[doi:10.1038/s41440-025-02411-9]
Schlaich, MP, Mahfoud, F, Böhm, M, Narkiewicz, K, Ruilope, L, Williams, B, Mancia, G, Sharif, F, Ribichini, F, Lung, TH, Shetty, S, Schmieder, RE (2025).

Renal Denervation in Patients With Moderate to Severe Chronic Kidney Disease

HYPERTENSION. Article. 82(12):2252-2261.
[doi:10.1161/HYPERTENSIONAHA.125.25470]
Mihailidou, AS, Mahfoud, F, Schlaich, M, Schmieder, R, Narkiewicz, K, Ruilope, L, Fahy, M, Böhm, M, Mancia, G, Nickel, L, Hettrick, DA, Weil, J (2025).

Sex stratified analysis of patients with resistant hypertension from the Global SYMPLICITY Registry of renal denervation

HYPERTENSION RESEARCH. Article. 49(3):904-915.
[doi:10.1038/s41440-025-02446-y]
Ostrominski, JW, Harrington, J, Claggett, BL, Filippatos, G, Desai, AS, Jhund, PS, Henderson, AD, Lam, CSP, Senni, M, Shah, SJ, Voors, AA, Zannad, F, Rossing, P, Ruilope, LM, Anker, SD, Pitt, B, Agarwal, R, Brinker, MD, Rohwedder, K, Lay-Flurrie, J, Lage, A, McMurray, JJV, Solomon, SD, Vaduganathan, M (2025).

Anthropometric Measures, Cardiovascular Outcomes, and Treatment Effects of Finerenone in Cardiovascular-Kidney-Metabolic Disease Pooled Participant-Level Analysis of 3 Global Trials

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Article. 86(20):1781-1801.
[doi:10.1016/j.jacc.2025.08.039]
Ruilope, LM, Pitt, B, de la Sierra, A, Ruiz-Hurtado, G (2025).

Towards a better prevention in cardio-kidney metabolic syndrome: Role of aldosterone and albuminuria

NEFROLOGIA. Editorial Material. 45(9).
[doi:10.1016/j.nefro.2025.501399]
Fernández, MG, Sen, AB, Pablo, PC, Blasco, AV, Hurtado, GR, Delgado, C, Cubillos, C, Boscá, L, Velasco, MF (2025).

Atrial Myopathy and Heart Failure: Immunomolecular Mechanisms and Clinical Implications

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 26(17).
[doi:10.3390/ijms26178210]
de la Sierra, A, Ruilope, LM, Staplin, N, Stergiou, GS, Vinyoles, E, Williams, B (2025).

Mortality risks in different subtypes of white-coat hypertension: implications for the diagnosis of white-coat hypertension

JOURNAL OF HYPERTENSION. Article. 43(8):1450-1456.
[doi:10.1097/HJH.0000000000004076]
Ostrominski, JW, Filippatos, G, Claggett, BL, Miao, ZM, Desai, AS, Jhund, PS, Henderson, AD, Scheerer, MF, Rohwedder, K, Amarante, F, Brinker, M, Lay-Flurrie, J, Lam, CSP, Senni, M, Shah, SJ, Voors, AA, Zannad, F, Rossing, P, Ruilope, LM, Anker, SD, Pitt, B, Agarwal, R, Mcmurray, JJV, Solomon, SD, Vaduganathan, M (2025).

Efficacy and Safety of Finerenone in Heart Failure With Preserved Ejection Fraction A FINE-HEART Analysis

JACC-Heart Failure. Article. 13(8).
[doi:10.1016/j.jchf.2025.03.041]
Mahfoud, F, Kandzari, DE, Schlaich, MP, Schmieder, RE, Lauder, L, Ruilope, L, Narkiewicz, K, Williams, B, Hettrick, DA, Lung, TH, Ribichini, F, Weil, J, Sharif, F, Mancia, G, Böhm, M (2025).

Long-term outcomes following radiofrequency renal denervation: meta-analysis of 18 reports

European Journal of Preventive Cardiology. Article.
[doi:10.1093/eurjpc/zwaf368]
Navaneethan, SD, Anker, SD, Filippatos, G, Pitt, B, Rossing, P, Ruilope, LM, August, P, Brinker, M, Lage, A, Roberts, L, Scott, C, Sarafidis, P (2025).

Efficacy and safety of finerenone in patients with an acute change in estimated glomerular filtration rate in the prespecified FIDELITY pool analysis

KIDNEY INTERNATIONAL. Article. 108(1):136-144.
[doi:10.1016/j.kint.2025.03.018]
Guerrero-Mauvecin, J, Villar-Gómez, N, Miño-Izquierdo, L, Povo-Retana, A, Ramos, AM, Ruiz-Hurtado, G, Sanchez-Niño, MD, Ortiz, A, Sanz, AB (2025).

Antioxidant Effects of SGLT2 Inhibitors on Cardiovascular-Kidney-Metabolic (CKM) Syndrome

Antioxidants. Review. 14(6).
[doi:10.3390/antiox14060701]
Wada T, Anker SD, Liu Z, Lee BW, Lee CT, Rossing P, Ruilope LM, Ahlers C, Brinker M, Mann A, Yamashita S, Pitt B (2025).

Efficacy and Safety of Finerenone in Asian Patients with Type 2 Diabetes and Chronic Kidney Disease: A FIDELITY Analysis.

Kidney Diseases. Article. 11(1):402-415.
[doi:10.1159/000545415]
Pabon, MA, Filippatos, G, Claggett, BL, Miao, MZ, Desai, AS, Jhund, PS, Henderson, A, Brinker, M, Schloemer, P, Hofmeister, L, Li, L, Lam, CSP, Senni, M, Shah, SJ, Voors, AA, Zannad, F, Rossing, P, Ruilope, LM, Anker, SD, Pitt, B, Agarwal, R, Mcmurray, JJV, Solomon, SD, Vaduganathan, M (2025).

Finerenone Reduces New-Onset Atrial Fibrillation Across the Spectrum of Cardio-Kidney-Metabolic Syndrome The FINE-HEART Pooled Analysis

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Article. 85(17):1649-1660.
[doi:10.1016/j.jacc.2025.03.429]
Mentz, RJ, Anker, SD, Pitt, B, Rossing, P, Ruilope, LM, Gebel, M, Kolkhof, P, Lawatscheck, R, Rohwedder, K, Bakris, GL, FIDELIO-DKD FIGARO-DKD Investigators (2025).

Efficacy and safety of finerenone in patients with chronic kidney disease and type 2 diabetes by diuretic use: A FIDELITY analysis

EUROPEAN JOURNAL OF HEART FAILURE. Article. 27(5):764-774.
[doi:10.1002/ejhf.3569]
Ostrominski, JW, Claggett, BL, Miao, ZM, Filippatos, G, Desai, AS, Jhund, PS, Henderson, A, Brinker, M, Schloemer, P, Viswanathan, P, Lage, A, Rohwedder, K, Lam, CSP, Senni, M, Shah, SJ, Voors, AA, Zannad, F, Rossing, P, Ruilope, LM, Anker, SD, Pitt, B, Agarwal, R, McMurray, JJV, Solomon, SD, Vaduganathan, M (2025).

Efficacy and Safety of Finerenone in Type 2 Diabetes: A Pooled Analysis of Trials of Heart Failure and Chronic Kidney Disease

DIABETES CARE. Article. 48(5).
[doi:10.2337/dc24-1873]
Ferreira, JP, Anker, SD, Palmer, BF, Pitt, B, Rossing, P, Ruilope, LM, Wanner, C, Farag, YMK, Horvat-Broecker, A, Lambelet, M, Brinker, M, Rohwedder, K, Filippatos, G (2025).

Incident hyperkalaemia risk model in chronic kidney disease and diabetes: the FIDELITY programme

EUROPEAN HEART JOURNAL. Article.
[doi:10.1093/eurheartj/ehaf258]
Saco-Ledo, G, Ruilope, LM, Lucia, A (2025).

Response to letter 'Are individuals with resistant hypertension not responsive to exercise when using ambulatory blood pressure monitoring?'

JOURNAL OF HYPERTENSION. Letter. 43(4):725-726.
[doi:10.1097/HJH.0000000000003962]
Segura, J, Armario, P (2025).

Refractory arterial hypertension. What can we offer these patients?

Hipertension y Riesgo Vascular. Editorial Material. 42(2):65-66.
[doi:10.1016/j.hipert.2024.12.004]
de la Sierra, A, Ruilope, LM, Staplin, N, Stergiou, GS, Williams, B (2025).

Mortality risks in different subtypes of masked hypertension in the Spanish ambulatory blood pressure monitoring registry

JOURNAL OF HYPERTENSION. Article. 43(4):642-648.
[doi:10.1097/HJH.0000000000003950]
Saco-Ledo, G, Valenzuela, PL, Almazán-Polo, J, Plaza-Florido, A, Alejo, LB, Bustos, A, Río-García, A, Gálvez, BG, Rubio-González, E, Fiuza-Luces, C, León-Sanz, M, Boraita, A, Santos-Lozano, A, Ruilope, LM, Lucia, A (2025).

Acute physical exercise and ambulatory blood pressure in resistant hypertension

JOURNAL OF HYPERTENSION. Article. 43(3):445-455.
[doi:10.1097/HJH.0000000000003924]
Vázquez-Sánchez, S, Blasco, A, Fernández-Corredoira, P, Cantolla, P, Mercado-García, E, Rodríguez-Sánchez, E, González-Lafuente, L, Poveda, J, González-Moreno, D, Matutano, A, Peribañez, S, García-Consuegra, I, Volpe, M, Fernández-Velasco, M, Ruilope, LM, Ruiz-Hurtado, G (2025).

Recombinant Klotho administration after myocardial infarction reduces ischaemic injury and arrhythmias by blocking intracellular calcium mishandling and CaMKII activation

JOURNAL OF PATHOLOGY. Article. 265(3):342-356.
[doi:10.1002/path.6388]
Navarro-García, JA, Wehrens, XHT, Ruiz-Hurtado, G (2025).

Is fibroblast growth factor 23 a player or a trigger in atrial fibrillation?

European Journal of Preventive Cardiology. Editorial Material.
[doi:10.1093/eurjpc/zwaf053]
Singh, AK, James, G, Anker, SD, Pitt, B, Rossing, P, Ruilope, LM, Farjat, AE, Farag, YMK, Roberts, L, Filippatos, G (2025).

Finerenone Efficacy in Patients with Chronic Kidney Disease, Type 2 Diabetes, and Anemia in FIDELITY

Jacc-Advances. Article. 4(2).
[doi:10.1016/j.jacadv.2024.101524]
Márquez, DF, Ortiz, A, González-Moreno, D, Ruilope, LM, Ruiz-Hurtado, G (2025).

Finerenone: Evidence for Benefit in Early Stages of Cardiovascular-Kidney-Metabolic Syndrome

CardioRenal Medicine. Review. 15(1):619-625.
[doi:10.1159/000548494]
Guimaraes, P, Keller, A, Böhm, M, Lauder, L, Fehlmann, T, Ruilope, LM, Vinyoles, E, Gorostidi, M, Segura, J, Ruiz-Hurtado, G, Staplin, N, Williams, B, de la Sierra, A, Mahfoud, F (2025).

Artificial Intelligence-Derived Risk Prediction: A Novel Risk Calculator Using Office and Ambulatory Blood Pressure

HYPERTENSION. Article. 82(1):46-56.
[doi:10.1161/HYPERTENSIONAHA.123.22529]

2024

Vaduganathan M, Filippatos G, Claggett BL, Desai AS, Jhund PS, Henderson A, Brinker M, Kolkhof P, Schloemer P, Lay-Flurrie J, Viswanathan P, Lam CSP, Senni M, Shah SJ, Voors AA, Zannad F, Rossing P, Ruilope LM, Anker SD, Pitt B, Agarwal R, McMurray JJV, Solomon SD (2024).

Finerenone in heart failure and chronic kidney disease with type 2 diabetes: FINE-HEART pooled analysis of cardiovascular, kidney and mortality outcomes.

NATURE MEDICINE. Article. 30(12):3758-3764.
[doi:10.1038/s41591-024-03264-4]
Halimi JM, Sarafidis P, Azizi M, Bilo G, Burkard T, Bursztyn M, Camafort M, Chapman N, Cottone S, de Backer T, Deinum J, Delmotte P, Dorobantu M, Doumas M, Dusing R, Duly-Bouhanick B, Fauvel JP, Fesler P, Gaciong Z, Gkaliagkousi E, Gordin D, Grassi G, Grassos C, Guerrot D, Huart J, Izzo R, Jaén Águila F, Járai Z, Kahan T, Kantola I, Kociánová E, Limbourg F, Lopez-Sublet M, Mallamaci F, Manolis A, Marketou M, Mayer G, Mazza A, MacIntyre I, Mourad JJ, Muiesan ML, Nasr E, Nilsson P, Oliveras A, Ormezzano O, Paixão-Dias V, Papadakis I, Papadopoulos D, Perl S, Polónia J, Pontremoli R, Pucci G, Robles NR, Rubin S, Ruilope LM, Rump LC, Saeed S, Sanidas E, Sarzani R, Schmieder R, Silhol F, Sokolovic S, Solbu M, Soucek M, Stergiou G, Sudano I, Tabbalat R, Tengiz I, Triantafyllidi H, Tsioufis K, Václavík J, van der Giet M, der Niepen PV, Veglio F, Venzin R, Viigimaa M, Weber T, Widimsky J, Wuerzner G, Zelveian P, Zebekakis P, Lueders S, Persu A, Kreutz R, Vogt L (2024).

Management of patients with hypertension and chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. On behalf of the European Society of Hypertension Working Group on Hypertension and the Kidney.

BLOOD PRESSURE. Article. 33(1):2368800-2368800.
[doi:10.1080/08037051.2024.2368800]
Pitt, B, Agarwal, R, Anker, SD, Rossing, P, Ruilope, L, Herzog, CA, Greenberg, B, Pecoits, R, Lambelet, M, Lawatscheck, R, Scalise, A, Filippatos, G (2024).

Hypokalaemia in patients with type 2 diabetes and chronic kidney disease: the effect of finerenone-a FIDELITY analysis

European Heart Journal-Cardiovascular Pharmacotherapy. Article. 11(1):10-19.
[doi:10.1093/ehjcvp/pvae074]
de la Sierra, A, Ruilope, LM, Staplin, N, Gorostidi, M, Vinyoles, E, Segura, J, Armario, P, Oliveras, A, Williams, B (2024).

Resistant Hypertension and Mortality: An Observational Cohort Study

HYPERTENSION. Article. 81(11):2350-2356.
[doi:10.1161/HYPERTENSIONAHA.124.23276]
González-Lafuente, L, Mercado-García, E, Vázquez-Sánchez, S, González-Moreno, D, Boscá, L, Fernández-Velasco, M, Segura, J, Kuro-O, M, Ruilope, LM, Liaño, F, Ruiz-Hurtado, G (2024).

Interleukin-6 as a prognostic marker in acute renal injury and its klotho-dependent regulation

NEFROLOGIA. Article. 44(6):818-829.
[doi:10.1016/j.nefro.2024.04.002]
Rodríguez-Miguel, A, Fernández-Fernández, B, Ortiz, A, Gil, M, Rodríguez-Martín, S, Ruiz-Hurtado, G, Fernández-Antón, E, Ruilope, LM, de Abajo, FJ (2024).

Glucose-Lowering Drugs and Primary Prevention of Chronic Kidney Disease in Type 2 Diabetes Patients: A Real-World Primary Care Study

Pharmaceuticals. Article. 17(10).
[doi:10.3390/ph17101299]
Rodriguez-Sanchez, E, Aceves-Ripoll, J, Mercado-García, E, Navarro-García, JA, Andrés, A, Aguado, JM, Segura, J, Ruilope, LM, Fernández-Ruiz, M, Ruiz-Hurtado, G (2024).

Donor-Dependent Variations in Systemic Oxidative Stress and Their Association with One-Year Graft Outcomes in Kidney Transplantation

AMERICAN JOURNAL OF NEPHROLOGY. Article. 55(5):509-519.
[doi:10.1159/000539509]
Castillo-García, A, Valenzuela, PL, Saco-Ledo, G, Carrera-Bastos, P, Ruilope, LM, Santos-Lozano, A, Lucia, A (2024).

Lifestyle and cardiovascular risk in working young adults: insights from a nationwide Spanish cohort

REVISTA ESPANOLA DE CARDIOLOGIA. Article. 77(10):821-831.
[doi:10.1016/j.rec.2024.02.006]
Anfaiha-Sanchez M, Santiago-Hernandez A, Lopez JA, Lago-Baameiro N, Pardo M, Martin-Blazquez A, Vazquez J, Ruiz-Hurtado G, Barderas MG, Segura J, Ruilope LM, Martin-Lorenzo M, Alvarez-Llamas G (2024).

Urinary extracellular vesicles as a monitoring tool for renal damage in patients not meeting criteria for chronic kidney disease.

Journal Of Extracellular Biology. Article. 3(9).
[doi:10.1002/jex2.170]
Filippatos, G, Anker, SD, Bakris, GL, Rossing, P, Ruilope, LM, Coats, AJS, von Haehling, S, Ponikowski, P, Rosano, GMC, Brinker, M, Farjat, AE, Roberts, L, Pitt, B (2024).

Finerenone and left ventricular hypertrophy in chronic kidney disease and type 2 diabetes

ESC Heart Failure. Article. 12(1):185-188.
[doi:10.1002/ehf2.14962]
Halimi JM, Sarafidis P, Azizi M, Bilo G, Burkard T, Bursztyn M, Camafort M, Chapman N, Cottone S, de Backer T, Deinum J, Delmotte P, Dorobantu M, Doumas M, Dusing R, Duly-Bouhanick B, Fauvel JP, Fesler P, Gaciong Z, Gkaliagkousi E, Gordin D, Grassi G, Grassos C, Guerrot D, Huart J, Izzo R, Águila FJ, Járai Z, Kahan T, Kantola I, Kociánová E, Limbourg FP, Lopez-Sublet M, Mallamaci F, Manolis A, Marketou M, Mayer G, Mazza A, MacIntyre IM, Mourad JJ, Muiesan ML, Nasr E, Nilsson P, Oliveras A, Ormezzano O, Paixão-Dias V, Papadakis I, Papadopoulos D, Perl S, Polónia J, Pontremoli R, Pucci G, Robles NR, Rubin S, Ruilope LM, Rump LC, Saeed S, Sanidas E, Sarzani R, Schmieder R, Silhol F, Sokolovic S, Solbu M, Soucek M, Stergiou G, Sudano I, Tabbalat R, Tengiz I, Triantafyllidi H, Tsioufis K, Václavík J, van der Giet M, Van der Niepen P, Veglio F, Venzin RM, Viigimaa M, Weber T, Widimsky J, Wuerzner G, Zelveian P, Zebekakis P, Lueders S, Persu A, Kreutz R, Vogt L (2024).

Screening and management of hypertensive patients with chronic kidney disease referred to Hypertension Excellence Centres among 27 countries. A pilot survey based on questionnaire.

JOURNAL OF HYPERTENSION. Article. 42(9):1544-1554.
[doi:10.1097/HJH.0000000000003756]
Santiago-Hernandez, A, Martin-Lorenzo, M, Gómez-Serrano, M, Lopez, JA, Martin-Blazquez, A, Vellosillo, P, Minguez, P, Martinez, PJ, Vazquez, J, Ruiz-Hurtado, G, Barderas, MG, Sarafidis, P, Segura, J, Ruilope, LM, Alvarez-Llamas, G (2024).

The Urinary Glycopeptide Profile Differentiates Early Cardiorenal Risk in Subjects Not Meeting Criteria for Chronic Kidney Disease

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 25(13).
[doi:10.3390/ijms25137005]
de la Sierra, A, Staplin, N, Ruilope, LM, Gorostidi, M, Vinyoles, E, Segura, J, Baigent, C, Williams, B (2024).

A blunted nocturnal blood pressure decline is associated with all-cause and cardiovascular mortality

JOURNAL OF HYPERTENSION. Article. 42(7):1197-1202.
[doi:10.1097/HJH.0000000000003712]
Armario, P, Gómez-Choco, M, García-Sánchez, SM, Ruilope, LM, Williams, B, Sierra, AD (2024).

Clinic and ambulatory blood pressures, blood pressure phenotypes and mortality in patients with a previous stroke

HYPERTENSION RESEARCH. Article. 47(9):2503-2510.
[doi:10.1038/s41440-024-01760-1]
Böhm, M, de la Sierra, A, Mahfoud, F, Schwantke, I, Lauder, L, Haring, B, Vinyoles, E, Gorostidi, M, Segura, J, Williams, B, Staplin, N, Ruilope, LM (2024).

Office measurement vs. ambulatory blood pressure monitoring: associations with mortality in patients with or without diabetes

EUROPEAN HEART JOURNAL. Article. 45(31):2851-2861.
[doi:10.1093/eurheartj/ehae337]
Ruilope, LM (2024).

Commentary on 'Prevalence and factors associated with masked hypertension in chronic kidney disease'

JOURNAL OF HYPERTENSION. Editorial Material. 42(6):961-961.
[doi:10.1097/HJH.0000000000003682]
Vazquez, S, Blasco, A, Corredoira, P, Cantolla, P, Gonzalez-Lafuente, L, Poveda, J, Mercado-Garcia, E, Gonzalez-Moreno, D, Fernandez-Velasco, M, Ruiz-Hurtado, G (2024).

Cardioprotective effect of the anti-ageing protein Klotho on ischemic heart disease

CARDIOVASCULAR RESEARCH. Meeting Abstract. 120.
[doi:10.1093/cvr/cvae088.056]
Ruilope, LM, Ortiz, A, Ruiz-Hurtado, G (2024).

Hypertension and the kidney: an update

EUROPEAN HEART JOURNAL. Editorial Material. 45(17):1497-1499.
[doi:10.1093/eurheartj/ehad896]
Rivero, M, Fernández-Vidal, M, Sandino, J, Rico, RB, Moliz, C, Ruiz-Cabello, JE, Garcia-Galán, LC, González-García, C, Hernández-Velasco, P, Segura, J, Gutiérrez, E, Morales, E (2024).

Effect of Intravitreal Anti-Endothelial Growth Factor Agents on Renal Function in Patients With Diabetes Mellitus

Kidney International Reports. Article. 9(5):1397-1405.
[doi:10.1016/j.ekir.2024.02.003]
de la Sierra, A, Williams, B, Bursztyn, M, Parati, G, Stergiou, GS, Vinyoles, E, Segura, J, Gorostidi, M, Ruilope, LM (2024).

Prognostic Relevance of Short-Term Blood Pressure Variability. The Spanish ABPM Registry

HYPERTENSION. Article. 81(5):1125-1131.
[doi:10.1161/HYPERTENSIONAHA.124.22716]
Tangri, N, Ferguson, T, Leon, SJ, Anker, SD, Filippatos, G, Pitt, B, Rossing, P, Ruilope, LM, Farjat, AE, Farag, YMK, Schloemer, P, Lawatscheck, R, Rohwedder, K, Bakris, GL (2024).

Validation of the Klinrisk chronic kidney disease progression model in the FIDELITY population

Clinical Kidney Journal. Article. 17(4).
[doi:10.1093/ckj/sfae052]
de la Sierra, A, Staplin, N, Ruilope, LM, Baigent, C, Williams, B (2024).

Authors' reply

LANCET. Editorial Material. 403(10429):812-812.
[doi:10.1016/S0140-6736(23)02618-1]
Ebert, T, Anker, SD, Ruilope, LM, Fioretto, P, Fonseca, V, Umpierrez, GE, Birkenfeld, AL, Lawatscheck, R, Scott, C, Rohwedder, K, Rossing, P (2024).

Outcomes With Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes by Baseline Insulin Resistance

DIABETES CARE. Article. 47(3):362-370.
[doi:10.2337/dc23-1420]
Bansal, S, Canziani, MEF, Birne, R, Anker, SD, Bakris, GL, Filippatos, G, Rossing, P, Ruilope, LM, Farjat, AE, Kolkhof, P, Lage, A, Brinker, M, Pitt, B (2024).

Finerenone cardiovascular and kidney outcomes by age and sex: FIDELITY post hoc analysis of two phase 3, multicentre, double-blind trials

BMJ Open. Article. 14(3).
[doi:10.1136/bmjopen-2023-076444]
de la Sierra, A, Ruilope, LM, Martínez-Camblor, P, Vinyoles, E, Gorostidi, M, Segura, J, Williams, B (2024).

Impact of timing of antihypertensive treatment on mortality: an observational study from the Spanish Ambulatory Blood Pressure Monitoring Registry

JOURNAL OF HYPERTENSION. Article. 42(2):260-266.
[doi:10.1097/HJH.0000000000003581]
Perakakis, N, Bornstein, SR, Birkenfeld, AL, Linkermann, A, Demir, M, Anker, SD, Filippatos, G, Pitt, B, Rossing, P, Ruilope, LM, Kolkhof, P, Lawatscheck, R, Scott, C, Bakris, GL (2024).

Efficacy of finerenone in patients with type 2 diabetes, chronic kidney disease and altered markers of liver steatosis and fibrosis: A FIDELITY subgroup analysis

DIABETES OBESITY & METABOLISM. Article. 26(1):191-200.
[doi:10.1111/dom.15305]
Castillo-García, A, Valenzuela, PL, Saco-Ledo, G, Morales, JS, Ruilope, LM, Santos-Lozano, A, Lucia, A (2024).

Physical activity, chronic kidney disease, and cardiovascular risk: A study in half a million adults

SCANDINAVIAN JOURNAL OF MEDICINE & SCIENCE IN SPORTS. Article. 34(1).
[doi:10.1111/sms.14557]
Sastre-Oliva, T, Corbacho-Alonso, N, Rodriguez-Sanchez, E, Mercado-Garcia, E, Perales-Sanchez, I, Hernandez-Fernandez, G, Juarez-Alia, C, Tejerina, T, Lopez-Almodovar, LF, Padial, LR, Sanchez, PL, Martín-Nuñez, E, López-Andrés, N, Ruiz-Hurtado, G, Mourino-Alvarez, L, Barderas, MG (2024).

Albumin Redox Modifications Promote Cell Calcification Reflecting the Impact of Oxidative Status on Aortic Valve Disease and Atherosclerosis

Antioxidants. Article. 13(1).
[doi:10.3390/antiox13010108]

2023

Carasol, M, Muñoz Aguilera E, Ruilope, LM (2023).

Oral health, hypertension and cardiovascular diseases.

Hipertension y Riesgo Vascular. Editorial Material. 40(4):167-170.
[doi:10.1016/j.hipert.2023.04.001]
Sanz-Gómez, M, Manzano-Lista, FJ, Vega-Martín, E, González-Moreno, D, Alcalá, M, Gil-Ortega, M, Somoza, B, Pizzamiglio, C, Ruilope, LM, Aránguez, I, Kolkhof, P, Kreutz, R, Fernández-Alfonso, MS (2023).

Finerenone protects against progression of kidney and cardiovascular damage in a model of type 1 diabetes through modulation of proinflammatory and osteogenic factors

BIOMEDICINE & PHARMACOTHERAPY. Article. 168.
[doi:10.1016/j.biopha.2023.115661]
Flack, JM, Agarwal, R, Anker, SD, Pitt, B, Ruilope, LM, Rossing, P, Adler, SG, Fried, L, Jamerson, K, Toto, R, Brinker, M, Farjat, AE, Kolkhof, P, Lawatscheck, R, Joseph, A, Bakris, GL (2023).

Finerenone in Black Patients With Type 2 Diabetes and CKD: A Post hoc Analysis of the Pooled FIDELIO-DKD and FIGARO-DKD Trials

Kidney Medicine. Article. 5(12).
[doi:10.1016/j.xkme.2023.100730]
Agarwal, R, Tu, WZ, Farjat, AE, Fang, YMK, Toto, R, Kaul, S, Lawatscheck, R, Rohwedder, K, Ruilope, LM, Rossing, P, Pitt, B, Filippatos, G, Anker, SD, Bakris, GL (2023).

Impact of Finerenone-Induced Albuminuria Reduction on Chronic Kidney Disease Outcomes in Type 2 Diabetes A Mediation Analysis

ANNALS OF INTERNAL MEDICINE. Article. 176(12).
[doi:10.7326/M23-1023]
Bagudá, JD, Chaverri, AR, Pérez, PC, Aguilar-Rodríguez, F, Carmena, MDGC, Carmena, DGC, Pérez, SM, López, ML, de la Cruz, J, Guerra, JM, Segura, J, Ynsaurriaga, FA, Ruilope, LM, Jiménez, JFD (2023).

Twenty-four hour ambulatory blood pressure monitoring in patients with stable heart failure. Prevalence and associated factors

REVISTA ESPANOLA DE CARDIOLOGIA. Article. 76(11):852-861.
[doi:10.1016/j.rec.2023.02.018]
Camafort, M, Ihm, SH, Ruilope, LM (2023).

Renal denervation for the treatment of hypertension and kidney disease

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION. Review. 32(6):544-550.
[doi:10.1097/MNH.0000000000000928]
Song, J, Navarro-Garcia, JA, Wu, J, Saljic, A, Abu-Taha, I, Li, LG, Lahiri, SK, Keefe, JA, Aguilar-Sanchez, Y, Moore, OM, Yuan, Y, Wang, XL, Kamler, M, Mitch, WE, Ruiz-Hurtado, G, Hu, ZY, Thomas, SS, Dobrev, D, Wehrens, XHT, Li, N (2023).

Chronic kidney disease promotes atrial fibrillation via inflammasome pathway activation

JOURNAL OF CLINICAL INVESTIGATION. Article. 133(19).
[doi:10.1172/JCI167517]
Rossing, P, Anker, SD, Filippatos, G, Pitt, B, Ruilope, LM, Billings, LK, Green, JB, Koya, D, Mosenzon, O, Pantalone, KM, Ahlers, C, Lage, A, Lawatscheck, R, Scalise, A, Bakris, GL (2023).

The impact of obesity on cardiovascular and kidney outcomes in patients with chronic kidney disease and type 2 diabetes treated with finerenone: Post hoc analysis of the FIDELITY study

DIABETES OBESITY & METABOLISM. Article. 25(10):2989-2998.
[doi:10.1111/dom.15197]
Rosas, SE, Ruilope, LM, Anker, SD, Pitt, B, Rossing, P, Bonfanti, AAC, Correa-Rotter, R, González, F, Munoz, CFJ, Pergola, P, Umpierrez, GE, Scalise, A, Scott, C, Lawatscheck, R, Joseph, A, Bakris, GL (2023).

Finerenone in Hispanic Patients With CKD and Type 2 Diabetes: A Post Hoc FIDELITY Analysis

Kidney Medicine. Article. 5(10).
[doi:10.1016/j.xkme.2023.100704]
Poveda, J, González-Lafuente, L, Vázquez-Sánchez, S, Mercado-García, E, Rodríguez-Sánchez, E, García-Consuegra, I, Sanz, AB, Segura, J, Fernández-Velasco, M, Liaño, F, Ruilope, LM, Ruiz-Hurtado, G (2023).

Targeting the TWEAK-Fn14 pathway prevents dysfunction in cardiac calcium handling after acute kidney injury

JOURNAL OF PATHOLOGY. Article. 261(4):427-441.
[doi:10.1002/path.6200]
Koya, D, Anker, SD, Ruilope, LM, Rossing, P, Liu, ZH, Lee, BW, Lee, CT, Scott, C, Kolkhof, P, Lawatscheck, R, Wang, LL, Joseph, A, Pitt, B (2023).

Cardiorenal Outcomes with Finerenone in Asian Patients with Chronic Kidney Disease and Type 2 Diabetes: A FIDELIO-DKD post hoc Analysis

AMERICAN JOURNAL OF NEPHROLOGY. Article. 54(9-10):370-378.
[doi:10.1159/000532102]
González, CV, García, IH, Fernández-Friera, L, Ruiz-Hurtado, G, Morales, E, Solís, J, Galindo, A (2023).

Cardiovascular and renal health: Preeclampsia as a risk marker

NEFROLOGIA. Review. 43(3):269-280.
[doi:10.1016/j.nefroe.2022.04.009]
Rossing P, Burgess E, Agarwal R, Anker SD, Filippatos G, Pitt B, Ruilope LM, Gillard P, MacIsaac RJ, Wainstein J, Joseph A, Brinker M, Roessig L, Scott C, Bakris GL (2023).

Erratum. Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes According to Baseline HbA1c and Insulin Use: An Analysis From the FIDELIO-DKD Study. Diabetes Care 2022;45:888-897.

DIABETES CARE. Correction. 46(9):1721-1721.
[doi:10.2337/dc23-er09]
Mahfoud, F, Mancia, G, Schmieder, RE, Ruilope, L, Narkiewicz, K, Schlaich, M, Williams, B, Ribichini, F, Weil, J, Almerri, K, Sharif, F, Lauder, L, Wanten, M, Fahy, M, Boehm, M (2023).

Outcomes Following Radiofrequency Renal Denervation According to Antihypertensive Medications: Subgroup Analysis of the Global SYMPLICITY Registry DEFINE

HYPERTENSION. Article. 80(8):1759-1770.
[doi:10.1161/HYPERTENSIONAHA.123.21283]
Agarwal, R, Pitt, B, Rossing, P, Anker, SD, Filippatos, G, Ruilope, LM, Kovesdy, CP, Tuttle, K, Vaduganathan, M, Wanner, C, Bansilal, S, Gebel, M, Joseph, A, Lawatscheck, R, Bakris, GL (2023).

Modifiability of Composite Cardiovascular Risk Associated With Chronic Kidney Disease in Type 2 Diabetes With Finerenone

JAMA Cardiology. Article. 8(8):732-741.
[doi:10.1001/jamacardio.2023.1505]
Staplin, N, Sierra, AD, Ruilope, LM, Emberson, JR, Vinyoles, E, Gorostidi, M, -Hurtado, GR, Segura, J, Baigent, C, Williams, B (2023).

Relationship between clinic and ambulatory blood pressure and mortality: an observational cohort study in 59 124 patients

LANCET. Article. 401(10393):2041-2050.
[doi:10.1016/S0140-6736(23)00733-X]
McGill, JB, Agarwal, R, Anker, SD, Bakris, GL, Filippatos, G, Pitt, B, Ruilope, LM, Birkenfeld, AL, Caramori, ML, Brinker, M, Joseph, A, Lage, A, Lawatscheck, R, Scott, C, Rossing, P, FIDELIO-DKD Investigator, FIGARO-DKD Investigator (2023).

Effects of finerenone in people with chronic kidney disease and type 2 diabetes are independent of HbA1c at baseline, HbA1c variability, diabetes duration and insulin use at baseline

DIABETES OBESITY & METABOLISM. Article. 25(6):1512-1522.
[doi:10.1111/dom.14999]
Sarafidis, P, Agarwal, R, Pitt, B, Wanner, C, Filippatos, G, Boletis, J, Tuttle, KR, Ruilope, LM, Rossing, P, Toto, R, Anker, SD, Liu, ZH, Joseph, A, Ahlers, C, Brinker, M, Lawatscheck, R, Bakris, G (2023).

Outcomes with Finerenone in Participants with Stage 4 CKD and Type 2 Diabetes A FIDELITY Subgroup Analysis

Clinical Journal of the American Society of Nephrology. Article. 18(5):602-612.
[doi:10.2215/CJN.0000000000000149]
Corbacho-Alonso, N, Rodríguez-Sánchez, E, Sastre-Oliva, T, Mercado-García, E, Perales-Sánchez, I, Juarez-Alia, C, López-Almodovar, LF, Padial, LR, Tejerina, T, Mourino-Alvarez, L, Ruiz-Hurtado, G, Barderas, MG (2023).

Global Oxidative Status Is Linked to Calcific Aortic Stenosis: The Differences Due to Diabetes Mellitus and the Effects of Metformin

Antioxidants. Article. 12(5).
[doi:10.3390/antiox12051024]
Valenzuela, PL, Ruilope, LM, Santos-Lozano, A, Wilhelm, M, Kränkel, N, Fiuza-Luces, C, Lucia, A (2023).

Exercise benefits in cardiovascular diseases: from mechanisms to clinical implementation

EUROPEAN HEART JOURNAL. Review. 44(21):1874-1889.
[doi:10.1093/eurheartj/ehad170]
Rossing P, Garweg JG, Anker SD, Osonoi T, Pitt B, Rosas SE, Ruilope LM, Zhu D, Brinker M, Finis D, Leal S, Schmelter T, Bakris G (2023).

Effect of finerenone on the occurrence of vision-threatening complications in patients with non-proliferative diabetic retinopathy: Pooled analysis of two studies using routine ophthalmological examinations from clinical trial participants (ReFineDR/DeFineDR).

DIABETES OBESITY & METABOLISM. Article. 25(3):894-898.
[doi:10.1111/dom.14915]
Ruilope LM, Pitt B, Anker SD, Rossing P, Kovesdy CP, Pecoits-Filho R, Pergola P, Joseph A, Lage A, Mentenich N, Scheerer MF, Bakris GL (2023).

Kidney outcomes with finerenone: An analysis from the FIGARO-DKD study.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 38(2):372-383.
[doi:10.1093/ndt/gfac157]
Agarwal, R, Pitt, B, Palmer, BF, Kovesdy, CP, Burgess, E, Filippatos, G, Malyszko, J, Ruilope, LM, Rossignol, P, Rossing, P, Pecoits, R, Anker, SD, Joseph, A, Lawatscheck, R, Wilson, D, Gebel, M, Bakris, GL (2023).

A comparative post hoc analysis of finerenone and spironolactone in resistant hypertension in moderate-to-advanced chronic kidney disease

Clinical Kidney Journal. Article. 16(2):293-302.
[doi:10.1093/ckj/sfac234]
Filippatos, G, Anker, SD, August, P, Coats, AJS, Januzzi, JL, Mankovsky, B, Rossing, P, Ruilope, LM, Pitt, B, Sarafidis, P, Teerlink, JR, Kapelios, CJ, Gebel, M, Brinker, M, Joseph, A, Lage, A, Bakris, G, Agarwal, R (2023).

Finerenone and effects on mortality in chronic kidney disease and type 2 diabetes: a FIDELITY analysis

European Heart Journal-Cardiovascular Pharmacotherapy. Article. 9(2):183-191.
[doi:10.1093/ehjcvp/pvad001]
Agarwal, R, Ruilope, LM, Ruiz-Hurtado, G, Haller, H, Schmieder, RE, Anker, SD, Filippatos, G, Pitt, B, Rossing, P, Lambelet, M, Nowack, C, Kolkhof, P, Joseph, A, Bakris, GL (2023).

Effect of finerenone on ambulatory blood pressure in chronic kidney disease in type 2 diabetes.

JOURNAL OF HYPERTENSION. Article. 41(2):295-302.
[doi:10.1097/HJH.0000000000003330]
Rossing, P, Agarwal, R, Anker, SD, Filippatos, G, Pitt, B, Ruilope, LM, Fonseca, V, Umpierrez, GE, Caramori, ML, Joseph, A, Lambelet, M, Lawatscheck, R, Bakris, GL (2023).

Finerenone in patients across the spectrum of chronic kidney disease and type 2 diabetes by glucagon-like peptide-1 receptor agonist use

DIABETES OBESITY & METABOLISM. Article. 25(2):407-416.
[doi:10.1111/dom.14883]
Frías A, Vargas F, Sandino J, Berzal R, Rivero M, Cordero L, Cavero T, Segura J, García F, Hernández E, Gutiérrez E, Auñón P, Zamanillo I, Pascual J, Morales E (2023).

Octogenarians with chronic kidney disease in the nephrology clinic: Progressors vs. non-progressors.

Frontiers In Nephrology. Article. 3:1114486-1114486.
[doi:10.3389/fneph.2023.1114486]
Ortiz A, Ferro CJ, Balafa O, Burnier M, Ekart R, Halimi JM, Kreutz R, Mark PB, Persu A, Rossignol P, Ruilope LM, Schmieder RE, Valdivielso JM, Del Vecchio L, Zoccali C, Mallamaci F, Sarafidis P, European Renal and Cardiovascular Medicine (EURECA-m) working group of the Europ (2023).

Mineralocorticoid receptor antagonists for nephroprotection and cardioprotection in patients with diabetes mellitus and chronic kidney disease.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 38(1):10-25.
[doi:10.1093/ndt/gfab167]
González-Lafuente, L, Navarro-García, JA, Valero-Almazán, A, Rodríguez-Sánchez, E, Vázquez-Sánchez, S, Mercado-García, E, Pineros, P, Poveda, J, Fernández-Velasco, M, Kuro-O, M, Ruilope, LM, Ruiz-Hurtado, G (2023).

Partial Genetic Deletion of Klotho Aggravates Cardiac Calcium Mishandling in Acute Kidney Injury

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 24(2).
[doi:10.3390/ijms24021322]

2022

Manzano-Lista, FJ, Sanz-Gómez, M, González-Moreno, D, Vega-Martín, E, Gil-Ortega, M, Schulz, A, Rubio, MA, Ruiz-Hurtado, G, Ruilope, LM, Aránguez, I, Kreutz, R, Fernández-Alfonso, MS (2022).

Imbalance in Bone Morphogenic Proteins 2 and 7 Is Associated with Renal and Cardiovascular Damage in Chronic Kidney Disease.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 24(1).
[doi:10.3390/ijms24010040]
Ruilope, LM, Ruiz-Hurtado, G (2022).

Counteracting aldosterone in cardiorenal disease in type 2 diabetes through finerenone administration.

Hipertension y Riesgo Vascular. Article. 40(2):55-57.
[doi:10.1016/j.hipert.2022.11.002]
Filippatos, G, Anker, SD, Pitt, B, McGuire, DK, Rossing, P, Ruilope, LM, Butler, J, Jankowska, EA, Michos, ED, Farmakis, D, Farjat, AE, Kolkhof, P, Scalise, A, Joseph, A, Bakris, GL, Agarwal, R (2022).

Finerenone efficacy in patients with chronic kidney disease, type 2 diabetes and atherosclerotic cardiovascular disease

European Heart Journal-Cardiovascular Pharmacotherapy. Article. 9(1):85-93.
[doi:10.1093/ehjcvp/pvac054]
Ruilope LM, Ortiz A, Lucia A, Miranda B, Alvarez-Llamas G, Barderas MG, Volpe M, Ruiz-Hurtado G, Pitt B (2022).

Prevention of cardiorenal damage: importance of albuminuria.

EUROPEAN HEART JOURNAL. Review. 44(13):1112-1123.
[doi:10.1093/eurheartj/ehac683]
Rossing P, Anker SD, Filippatos G, Pitt B, Ruilope LM, Birkenfeld AL, McGill JB, Rosas SE, Joseph A, Gebel M, Roberts L, Scheerer MF, Bakris GL, Agarwal R (2022).

Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes by Sodium-Glucose Cotransporter 2 Inhibitor Treatment: The FIDELITY Analysis.

DIABETES CARE. Article. 45(12):2991-2998.
[doi:10.2337/dc22-0294]
Ruilope LM, Agarwal R, Anker SD, Filippatos G, Pitt B, Rossing P, Sarafidis P, Schmieder RE, Joseph A, Rethemeier N, Nowack C, Bakris GL (2022).

Blood Pressure and Cardiorenal Outcomes With Finerenone in Chronic Kidney Disease in Type 2 Diabetes.

HYPERTENSION. Article. 79(12):2685-2695.
[doi:10.1161/HYPERTENSIONAHA.122.19744]
Mahfoud F, Mancia G, Schmieder RE, Ruilope L, Narkiewicz K, Schlaich M, Williams B, Ribichini F, Weil J, Kao HL, Rodriguez-Leor O, Noory E, Ong TK, Unterseeh T, de Araújo Gonçalves P, Zirlik A, Almerri K, Sharif F, Lauder L, Wanten M, Fahy M, Böhm M (2022).

Cardiovascular Risk Reduction After Renal Denervation According to Time in Therapeutic Systolic Blood Pressure Range.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Article. 80(20):1871-1880.
[doi:10.1016/j.jacc.2022.08.802]
Filippatos G, Anker SD, Pitt B, Rossing P, Joseph A, Kolkhof P, Lambelet M, Lawatscheck R, Bakris GL, Ruilope LM, Agarwal R (2022).

Finerenone and Heart Failure Outcomes by Kidney Function/Albuminuria in Chronic Kidney Disease and Diabetes.

JACC-Heart Failure. Article. 10(11):860-870.
[doi:10.1016/j.jchf.2022.07.013]
Pitt, B, Agarwal, R, Anker, SD, Ruilope, LM, Rossing, P, Ahlers, C, Brinker, M, Joseph, A, Lambelet, M, Lawatscheck, R, Filippatos, GS (2022).

Association of Finerenone Use With Reduction in Treatment-Emergent Pneumonia and COVID-19 Adverse Events Among Patients With Type 2 Diabetes and Chronic Kidney Disease A FIDELITY Pooled Secondary Analysis

JAMA Network Open. Article. 5(10).
[doi:10.1001/jamanetworkopen.2022.36123]
Nuche, J, Bertolo, JDC, Clement, IM, Sanchez, VS, Cebada, FS, Mancebo, E, Enguita, AB, Alonso-Riano, M, Ruiz-Hurtado, G, Lopez-Azor, JC, Hernandez-Perez, FJ, Castrodeza, J, Gonzalez, JS, Ynsaurriaga, FA, Carmena, MDGC, Delgado, JF (2022).

Rationale and Protocol of the Multimodality Evaluation of Antibody-Mediated Injury in Heart Transplantation (LEONE-HT) Observational Cross-Sectional Study

Methods And Protocols. Article. 5(5).
[doi:10.3390/mps5050075]
Messerli, FH, Bavishi, C, Brguljan, J, Burnier, M, Dobner, S, Elijovich, F, Ferdinand, KC, Kjeldsen, S, Laffer, CL, Ram, CVS, Rexhaj, E, Ruilope, LM, Shalaeva, EV, Siontis, GCM, Staessen, JA, Textor, SC, Vongpatanasin, W, Vogt, L, Volpe, M, Wang, JG, Williams, B (2022).

Renal denervation in the antihypertensive arsenal - knowns and known unknowns

JOURNAL OF HYPERTENSION. Review. 40(10):1859-1875.
[doi:10.1097/HJH.0000000000003171]
Gorostidi, M, Gijon-Conde, T, de la Sierra, A, Rodilla, E, Rubio, E, Vinyoles, E, Oliveras, A, Santamaria, R, Segura, J, Molinero, A, Perez-Manchon, D, Abad, M, Abellan, J, Armario, P, Banegas, JR, Camafort, M, Catalina, C, Coca, A, Divison, JA, Domenech, M, Martell, N, Martin-Rioboo, E, Morales-Olivas, F, Pallares, V, Pérez de Isla L, Prieto, MA, Redon, J, Ruilope, LM, Garcia-Donaire, JA (2022).

Guía práctica sobre el diagnóstico y tratamiento de la hipertensión arterial en España, 2022. Sociedad Española de Hipertensión - Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA).

Hipertension y Riesgo Vascular. Article. 39(4):174-194.
[doi:10.1016/j.hipert.2022.09.002]
Ruilope LM, Ruiz-Hurtado G (2022).

Blood pressure control according to type 2 diabetes status.

Lancet Diabetes & Endocrinology. Editorial Material. 10(9):612-613.
[doi:10.1016/S2213-8587(22)00191-7]
Junho CVC, GonzÁlez-Lafuente L, Neres-Santos RS, Navarro-García JA, Rodríguez-Sánchez E, Ruiz-Hurtado G, Carneiro-Ramos MS (2022).

Klotho relieves inflammation and exerts a cardioprotective effect during renal ischemia/reperfusion-induced cardiorenal syndrome.

BIOMEDICINE & PHARMACOTHERAPY. Article. 153:113515-113515.
[doi:10.1016/j.biopha.2022.113515]
Marqueza, DF, Rodriguez-Sanchez, E, De la Morena, JS, Ruilope, LM, Ruiz-Hurtado, G (2022).

Hypertension mediated kidney and cardiovascular damage and risk stratification: Redefining concepts

NEFROLOGIA. Review. 42(5):519-530.
[doi:10.1016/j.nefro.2021.10.003]
Schmieder, RE, Mahfoud, F, Mancia, G, Narkiewicz, K, Ruilope, L, Hutton, D, Cao, K, Hettrick, DA, Fahy, M, Schlaich, MP, Bohm, M, Pietzsch, JB (2022).

Clinical event reductions in high-risk patients after renal denervation projected from the global SYMPLICITY registry

European Heart Journal-Quality of Care and Clinical Outcomes. Article. 9(6):575-582.
[doi:10.1093/ehjqcco/qcac056]
Yanucil C, Kentrup D, Campos I, Czaya B, Heitman K, Westbrook D, Osis G, Grabner A, Wende AR, Vallejo J, Wacker MJ, Navarro-Garcia JA, Ruiz-Hurtado G, Zhang F, Song Y, Linhardt RJ, White K, Kapiloff MS, Faul C (2022).

Soluble a-klotho and heparin modulate the pathologic cardiac actions of fibroblast growth factor 23 in chronic kidney disease.

KIDNEY INTERNATIONAL. Article. 102(2):261-279.
[doi:10.1016/j.kint.2022.03.028]
Alvarez-Llamas G, Santiago-Hernandez A, Ruilope LM (2022).

Evidence of chronic kidney injury in patients not meeting KDIGO criteria for chronic kidney disease.

Clinical Kidney Journal. Editorial Material. 15(7):1217-1220.
[doi:10.1093/ckj/sfac007]
Valenzuela PL, Santos-Lozano A, Castillo-García A, Ruilope LM, Lucia A (2022).

Diabetes, Hypertension, and the Mediating Role of Lifestyle: A Cross-Sectional Analysis in a Large Cohort of Adults.

AMERICAN JOURNAL OF PREVENTIVE MEDICINE. Article. 63(1):21-29.
[doi:10.1016/j.amepre.2022.01.014]
Agarwal R, Anker SD, Filippatos G, Pitt B, Rossing P, Ruilope LM, Boletis J, Toto R, Umpierrez GE, Wanner C, Wada T, Scott C, Joseph A, Ogbaa I, Roberts L, Scheerer MF, Bakris GL (2022).

Effects of canagliflozin versus finerenone on cardiorenal outcomes: exploratory post-hoc analyses from FIDELIO-DKD compared to reported CREDENCE results.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 37(7):1261-1269.
[doi:10.1093/ndt/gfab336]
Val-Blasco, A, Prieto, P, Jaén, RI, Gil-Fernández, M, Pajares, M, Domenech, N, Terrón, V, Tamayo, M, Jorge, I, Vázquez, J, Bueno-Sen, A, Vallejo-Cremades, MT, Pombo-Otero, J, Sanchez-García, S, Ruiz-Hurtado, G, Gómez, AM, Zaragoza, C, Crespo-Leiro, MG, López-Collazo, E, Cuadrado, A, Delgado, C, Boscá, L, Fernández-Velasco, M (2022).

Specialized Proresolving Mediators Protect Against Experimental Autoimmune Myocarditis by Modulating Ca2+ Handling and NRF2 Activation

JACC-Basic to Translational Science. Article. 7(6):544-560.
[doi:10.1016/j.jacbts.2022.01.009]
Filippatos G, Pitt B, Agarwal R, Farmakis D, Ruilope LM, Rossing P, Bauersachs J, Mentz RJ, Kolkhof P, Scott C, Joseph A, Bakris GL, Anker SD (2022).

Finerenone in patients with chronic kidney disease and type 2 diabetes with and without heart failure: a prespecified subgroup analysis of the FIDELIO-DKD trial.

EUROPEAN JOURNAL OF HEART FAILURE. Article. 24(6):996-1005.
[doi:10.1002/ejhf.2469]
Aubert, L, Sandino, J, Gutierrez-Solis, E, Garcia-Martin, F, Segura, J, Porrini, E, Morales, E (2022).

Role of non-alcoholic fatty liver disease in the evolution of renal function in patients with diabetes mellitus.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 37(6):1125-1131.
[doi:10.1093/ndt/gfab176]
Agarwal R, Anker SD, Bakris G, Filippatos G, Pitt B, Rossing P, Ruilope L, Gebel M, Kolkhof P, Nowack C, Joseph A, FIDELIO-DKD and FIGARO-DKD Investigators (2022).

Investigating new treatment opportunities for patients with chronic kidney disease in type 2 diabetes: the role of finerenone.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 37(6):1014-1023.
[doi:10.1093/ndt/gfaa294]
Saco-Ledo G, Valenzuela PL, Ruilope LM, Lucia A (2022).

Physical Exercise in Resistant Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

Frontiers in Cardiovascular Medicine. Review. 9:893811-893811.
[doi:10.3389/fcvm.2022.893811]
Carneiro-Ramos MS, Ruiz-Hurtado G, Vieyra A (2022).

Editorial: Contribution of Uremic Compounds to Cardiorenal Syndrome Development.

Frontiers in Physiology. Editorial Material. 13:877182-877182.
[doi:10.3389/fphys.2022.877182]
Ruilope, LM, Ruiz-Hurtado, G, Tamargo, J (2022).

Editorial commentary: Adequate blood pressure control unattainable without adequate recognition and treatment of primary aldosteronism

TRENDS IN CARDIOVASCULAR MEDICINE. Article. 32(4):234-236.
[doi:10.1016/j.tcm.2021.04.003]
González-Lafuente, L, Navarro-García, JA, Rodríguez-Sánchez, E, Aceves-Ripoll, J, Poveda, J, Vázquez-Sánchez, S, Mercado-García, E, Fernández-Velasco, M, Kuro-O, M, Liano, F, Ruilope, LM, Ruiz-Hurtado, G (2022).

Interplay between mineral bone disorder and cardiac damage in acute kidney injury: from Ca2+ mishandling and preventive role of Klotho in mice to its potential mortality prediction in human

TRANSLATIONAL RESEARCH. Article. 243:60-77.
[doi:10.1016/j.trsl.2022.01.002]
Valenzuela, PL, Santos-Lozano, A, Torres-Barran, A, Morales, JS, Castillo-Garcia, A, Ruilope, LM, Rios-Insua, D, Ordovas, JM, Lucia, A (2022).

Poor self-reported sleep is associated with risk factors for cardiovascular disease: A cross-sectional analysis in half a million adults

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. Article. 52(5).
[doi:10.1111/eci.13738]
Bover, J, Bosch, R, Gorriz, JL, Urena, P, Ortiz, A, daSilva, I, Garcia-Trabanino, RA, Hueso, M, Trinidad, P, Jara, A, Furlano, M, Gelpi, R, Vila-Santandreu, A, Restrepo, CA, Sanchez-Baya, M, Arana, C, Goicoechea, M, Coll, V, Segura, J, Gutierrez, O, Kalantar-Zadeh, K, Sanchez, E, Ferreiros, A, Garcia-Maset, R (2022).

Kidneys also speak Spanish: Initiatives towards standardisation of our nephrology nomenclature

NEFROLOGIA. Editorial Material. 42(3):223-232.
[doi:10.1016/j.nefro.2021.04.011]
Garcia-Maset, R, Bover, J, De la Morena, JS, Diezhandino, MG, del Hoyo, JC, San Martin, JE, Rubio, LF, Ortiz, JG, Garcia-Donaire, JA, Garcia-Matarin, L, Garcia, SG, Perez, MIG, Moreno, JH, Ramos, PM, Bermudez, RM, Torres, MM, de Pablos-Velasco, P, Perez-Maraver, M, Fernandez, CS, Iparraguirre, ST, Gorriz, JL (2022).

Information and consensus document for the detection and management of chronic kidney disease

NEFROLOGIA. Article. 42(3):233-264.
[doi:10.1016/j.nefro.2021.07.010]
Rossing P, Burgess E, Agarwal R, Anker SD, Filippatos G, Pitt B, Ruilope LM, Gillard P, MacIsaac RJ, Wainstein J, Joseph A, Brinker M, Roessig L, Scott C, Bakris GL (2022).

Finerenone in Patients With Chronic Kidney Disease and Type 2 Diabetes According to Baseline HbA1c and Insulin Use: An Analysis From the FIDELIO-DKD Study.

DIABETES CARE. Article. 45(4):888-897.
[doi:10.2337/dc21-1944]
Vinyoles, E, Puig, C, Roso-Llorach, A, Soldevila, N, de la Sierra, A, Gorostidi, M, Segura, J, Divison-Garrote, JA, Muñoz MÁ, Ruilope, LM (2022).

Role of ambulatory blood pressure on prediction of cardiovascular disease. A cohort study.

JOURNAL OF HUMAN HYPERTENSION. Article. 37(4):279-285.
[doi:10.1038/s41371-022-00679-9]
Valenzuela PL, Santos-Lozano A, Barrán AT, Fernández-Navarro P, Castillo-García A, Ruilope LM, Ríos Insua D, Ordovas JM, Ley V, Lucia A (2022).

Joint association of physical activity and body mass index with cardiovascular risk: a nationwide population-based cross-sectional study.

European Journal of Preventive Cardiology. Letter. 29(2):50-52.
[doi:10.1093/eurjpc/zwaa151]
Junho CVC, GonzÁlez-Lafuente L, Navarro-García JA, Rodríguez-Sánchez E, Carneiro-Ramos MS, Ruiz-Hurtado G (2022).

Unilateral Acute Renal Ischemia-Reperfusion Injury Induces Cardiac Dysfunction through Intracellular Calcium Mishandling.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 23(4).
[doi:10.3390/ijms23042266]
Agarwal R, Filippatos G, Pitt B, Anker SD, Rossing P, Joseph A, Kolkhof P, Nowack C, Gebel M, Ruilope LM, Bakris GL (2022).

Cardiovascular and kidney outcomes with finerenone in patients with type 2 diabetes and chronic kidney disease: the FIDELITY pooled analysis.

EUROPEAN HEART JOURNAL. Article. 43(6):474-484.
[doi:10.1093/eurheartj/ehab777]
Filippatos G, Anker SD, Agarwal R, Ruilope LM, Rossing P, Bakris GL, Tasto C, Joseph A, Kolkhof P, Lage A, Pitt B (2022).

Finerenone Reduces Risk of Incident Heart Failure in Patients With Chronic Kidney Disease and Type 2 Diabetes: Analyses From the FIGARO-DKD Trial.

CIRCULATION. Article. 145(6):437-447.
[doi:10.1161/CIRCULATIONAHA.121.057983]
Navarro-Garcia, JA, Ruiz-Hurtado, G (2022).

Murine models of uremic cardiomyopathy as a necessary tool to unravel mechanisms involved in cardiorenal syndrome.

KIDNEY INTERNATIONAL. Editorial Material. 101(2):214-216.
[doi:10.1016/j.kint.2021.11.023]
Ruilope, LM, Ruiz-Hurtado, G, Miranda, B, Ortiz, A (2022).

Use of chronic kidney disease blind spot to prevent cardiorenal outcomes

EUROPEAN HEART JOURNAL. Editorial Material. 43(4):257-260.
[doi:10.1093/eurheartj/ehab456]
Ott, C, Mahfoud, F, Mancia, G, Narkiewicz, K, Ruilope, LM, Fahy, M, Schlaich, MP, Böhm M, Schmieder, RE (2022).

Renal denervation in patients with versus without chronic kidney disease: results from the global SYMPLICITY Registry with follow-up data of 3 years.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 37(2):304-310.
[doi:10.1093/ndt/gfab154]
Navarro-García JA, Salguero-Bodes R, GonzÁlez-Lafuente L, Martín-Nunes L, Rodríguez-Sánchez E, Bada-Bosch T, Hernández E, Mérida-Herrero E, Praga M, Solís J, Arribas F, Bueno H, Kuro-O M, Fernández-Velasco M, Ruilope LM, Delgado C, Ruiz-Hurtado G (2022).

The anti-aging factor Klotho protects against acquired long QT syndrome induced by uremia and promoted by fibroblast growth factor 23.

BMC Medicine. Article. 20(1):14-14.
[doi:10.1186/s12916-021-02209-9]
Rossing P, Agarwal R, Anker SD, Filippatos G, Pitt B, Ruilope LM, Amod A, Marre M, Joseph A, Lage A, Scott C, Bakris GL (2022).

Efficacy and safety of finerenone in patients with chronic kidney disease and type 2 diabetes by GLP-1RA treatment: A subgroup analysis from the FIDELIO-DKD trial.

DIABETES OBESITY & METABOLISM. Article. 24(1):125-134.
[doi:10.1111/dom.14558]
Bakris, GL, Ruilope, LM, Anker, SD, Filippatos, G, Pitt, B, Rossing, P, Fried, L, Roy-Chaudhury, P, Sarafidis, P, Ahlers, C, Brinker, M, Joseph, A, Lawatscheck, R, Agarwal, R (2022).

A prespecified exploratory analysis from FIDELITY examined finerenone use and kidney outcomes in patients with chronic kidney disease and type 2 diabetes

KIDNEY INTERNATIONAL. Article. 103(1):196-206.
[doi:10.1016/j.kint.2022.08.040]
Agarwal R, Joseph A, Anker SD, Filippatos G, Rossing P, Ruilope LM, Pitt B, Kolkhof P, Scott C, Lawatscheck R, Wilson DJ, Bakris GL (2022).

Hyperkalemia Risk with Finerenone: Results from the FIDELIO-DKD Trial.

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Article. 33(1):225-237.
[doi:10.1681/ASN.2021070942]
Rossing, Peter, Filippatos, Gerasimos, Agarwal, Rajiv, Anker, Stefan D., Pitt, Bertram, Ruilope, Luis M., Chan, Juliana C. N., Kooy, Adriaan, McCafferty, Kieran, Schernthaner, Guntram, Wanner, Christoph, Joseph, Amer, Scheerer, Markus F., Scott, Charlie, Bakris, George L. (2022).

Finerenone in Predominantly Advanced CKD and Type 2 Diabetes With or Without Sodium-Glucose Cotransporter-2 Inhibitor Therapy

Kidney International Reports. Article. 7(1):36-45.
[doi:10.1016/j.ekir.2021.10.008]
Rodríguez-Sánchez E, Navarro-García JA, Aceves-Ripoll J, González-Lafuente L, Baldan-Martin M, de la Cuesta F, Alvarez-Llamas G, Barderas MG, Segura J, Ruilope LM, Ruiz-Hurtado G (2022).

Prediction of the early response to spironolactone in resistant hypertension by the combination of matrix metalloproteinase-9 activity and arterial stiffness parameters.

European Heart Journal-Cardiovascular Pharmacotherapy. Article. 8(1):68-76.
[doi:10.1093/ehjcvp/pvaa086]

2021

Pitt B, Filippatos G, Agarwal R, Anker SD, Bakris GL, Rossing P, Joseph A, Kolkhof P, Nowack C, Schloemer P, Ruilope LM, FIGARO-DKD Investigators (2021).

Cardiovascular Events with Finerenone in Kidney Disease and Type 2 Diabetes.

NEW ENGLAND JOURNAL OF MEDICINE. Article. 385(24):2252-2263.
[doi:10.1056/NEJMoa2110956]
Saco-Ledo, G, Valenzuela, PL, Ramirez-Jimenez, M, Morales, JS, Castillo-Garcia, A, Blumenthal, JA, Ruilope, LM, Lucia, A (2021).

Acute Aerobic Exercise Induces Short-Term Reductions in Ambulatory Blood Pressure in Patients With Hypertension: A Systematic Review and Meta-Analysis

HYPERTENSION. Review. 78(6):1844-1858.
[doi:10.1161/HYPERTENSIONAHA.121.18099]
Ruilope, LM, Ruiz-Hurtado, G, Lucia, A (2021).

Preventing and managing hypertension: do not forget the night.

HYPERTENSION RESEARCH. Editorial Material. 44(12):1674-1675.
[doi:10.1038/s41440-021-00744-9]
Navarro-Garcia, JA, Gonzalez-Lafuente, L, Fernandez-Velasco, M, Ruilope, LM, Ruiz-Hurtado, G (2021).

Fibroblast Growth Factor-23-Klotho Axis in Cardiorenal Syndrome: Mediators and Potential Therapeutic Targets.

Frontiers in Physiology. Review. 12:775029-775029.
[doi:10.3389/fphys.2021.775029]
Santiago-Hernandez, A, Martin-Lorenzo, M, Martínez, PJ, Gómez-Serrano, M, Lopez, JA, Cannata, P, Esteban, V, Heredero, A, Aldamiz-Echevarria, G, Vázquez, J, Ruiz-Hurtado, G, Barderas, MG, Segura, J, Ruilope, LM, Alvarez-Llamas, G (2021).

Early renal and vascular damage within the normoalbuminuria condition

JOURNAL OF HYPERTENSION. Article. 39(11):2220-2231.
[doi:10.1097/HJH.0000000000002936]
Ruilope, LM, Valenzuela, PL, Lucia, A (2021).

Digital therapeutics and lifestyle: the start of a new era in the management of arterial hypertension?

EUROPEAN HEART JOURNAL. Editorial Material. 42(40):4123-4125.
[doi:10.1093/eurheartj/ehab694]
Gijón-Conde T, Rubio E, Gorostidi M, Vinyoles E, Armario P, Rodilla E, Segura J, Divisón-Garrote JA, García-Donaire JA, Molinero A, Ruilope LM (2021).

Documento de consenso sobre consulta telemática en hipertensión y riesgo vascular. Sociedad Española de Hipertensión-Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA).

Hipertension y Riesgo Vascular. Article. 38(4):186-196.
[doi:10.1016/j.hipert.2021.03.003]
Santos-Lozano A, Barrán AT, Fernández-Navarro P, Valenzuela PL, Castillo-Garcia A, Ruilope LM, Ríos Insua D, Ordovas JM, Ley V, Lucia A (2021).

Association between physical activity and cardiovascular risk factors: Dose and sex matter

JOURNAL OF SPORT AND HEALTH SCIENCE. Letter. 10(5):604-606.
[doi:10.1016/j.jshs.2021.03.002]
Corbacho-Alonso N, Baldán-Martín M, López JA, Rodríguez-Sánchez E, Martínez PJ, Mourino-Alvarez L, Sastre-Oliva T, Cabrera M, Calvo E, Padial LR, Vázquez J, Vivanco F, Alvarez-Llamas G, Ruiz-Hurtado G, Ruilope LM, Barderas MG (2021).

Cardiovascular Risk Stratification Based on Oxidative Stress for Early Detection of Pathology.

ANTIOXIDANTS & REDOX SIGNALING. Article. 35(8):602-617.
[doi:10.1089/ars.2020.8254]
Filippatos G, Bakris GL, Pitt B, Agarwal R, Rossing P, Ruilope LM, Butler J, Lam CSP, Kolkhof P, Roberts L, Tasto C, Joseph A, Anker SD, FIDELIO-DKD Investigators (2021).

Finerenone Reduces New-Onset Atrial Fibrillation in Patients With Chronic Kidney Disease and Type 2 Diabetes.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Article. 78(2):142-152.
[doi:10.1016/j.jacc.2021.04.079]
Santiago-Hernandez A, Martin-Lorenzo M, Martin-Blazquez A, Ruiz-Hurtado G, Barderas MG, Segura J, Ruilope LM, Alvarez-Llamas G (2021).

TCA Cycle and Fatty Acids Oxidation Reflect Early Cardiorenal Damage in Normoalbuminuric Subjects with Controlled Hypertension.

Antioxidants. Article. 10(7).
[doi:10.3390/antiox10071100]
Mera-Gallego, I, Molinero, A, Fornos-Perez, JA, Tous-Trepat, S, Andres-Rodriguez, NF, Prats-Mas, R, Rodilla, E, Gijon-Conde, T, Ruilope-Urioste, LM (2021).

Blood pressure measurement campaign (May Measurement Month) from community pharmacies in 2018: analysis of screening in Spain

Hipertension y Riesgo Vascular. Article. 38(3):109-118.
[doi:10.1016/j.hipert.2021.02.007]
Val-Blasco A, Gil-Fernández M, Rueda A, Pereira L, Delgado C, Smani T, Ruiz Hurtado G, Fernández-Velasco M (2021).

Ca(2+) mishandling in heart failure: Potential targets.

Acta Physiologica. Review. 232(3).
[doi:10.1111/apha.13691]
Rodríguez-Sánchez E, Navarro-García JA, Aceves-Ripoll J, González-Lafuente L, Corbacho-Alonso N, Baldan-Martín M, Madruga F, Alvarez-Llamas G, Barderas MG, Ruilope LM, Ruiz-Hurtado G (2021).

Analysis of global oxidative status using multimarker scores reveals a specific association between renal dysfunction and diuretic therapy in older adults.

JOURNALS OF GERONTOLOGY SERIES A-BIOLOGICAL SCIENCES AND MEDICAL SCIENCES. Article. 76(7):1198-1205.
[doi:10.1093/gerona/glab012]
Saco-Ledo G, Valenzuela PL, Castillo-García A, Arenas J, León-Sanz M, Ruilope LM, Lucia A (2021).

Response to Letter to the Editor.

OBESITY REVIEWS. Letter. 22(6).
[doi:10.1111/obr.13253]
Bover J, Bosch R, Ureña P, Trinidad P, Jara A, Górriz JL, Furlano M, García-Trabanino RA, Gelpi R, Ortiz A, Restrepo CA, Sánchez-Baya M, Arana C, Goicoechea M, Coll V, Segura J, Gutiérrez O, Sánchez E, Ferreiro A, García-Maset R (2021).

Kidneys also speak Spanish.

NEFROLOGIA. Letter. 41(2):224-226.
[doi:10.1016/j.nefroe.2020.11.012]
Ramos E, Lajarín-Cuesta R, Arribas RL, García-Frutos EM, González-Lafuente L, Egea J, de Los Ríos C, Romero A (2021).

In Silico Prediction of the Toxic Potential of Neuroprotective Bifunctional Molecules Based on Chiral N-Propargyl-1,2-amino Alcohol Derivatives.

CHEMICAL RESEARCH IN TOXICOLOGY. Article. 34(5):1245-1249.
[doi:10.1021/acs.chemrestox.0c00519]
Poveda J, Vázquez-Sánchez S, Sanz AB, Ortiz A, Ruilope LM, Ruiz-Hurtado G (2021).

TWEAK-Fn14 as a common pathway in the heart and the kidneys in cardiorenal syndrome.

JOURNAL OF PATHOLOGY. Review. 254(1):5-19.
[doi:10.1002/path.5631]
Molinero, A, Calvo, E, Beaney, T, Day, E, Prats-Mas, R, Fornos, JA, Mera-Gallego, I, Tous, S, de Andres, NF, Rodilla, E, Gijon, T, Perez-Manchon, D, Poulter, NR, Ruiz-Hurtado, G, Ruilope, LM (2021).

May Measurement Month 2019: an analysis of blood pressure screening results from Spain

EUROPEAN HEART JOURNAL SUPPLEMENTS. Article. 23(B):138-140.
[doi:10.1093/eurheartj/suab060]
Bover J, Bosch R, Ureña P, Trinidad P, Jara A, Górriz JL, Furlano M, García-Trabanino RA, Gelpi R, Ortiz A, Restrepo CA, Sánchez-Baya M, Arana C, Goicoechea M, Coll V, Segura J, Gutiérrez O, Sánchez E, Ferreiro A, García-Maset R (2021).

Kidneys also speak Spanish.

NEFROLOGIA. Letter. 41:225-226.
[doi:10.1016/j.nefro.2020.11.002]
Valenzuela PL, Carrera-Bastos P, Gálvez BG, Ruiz-Hurtado G, Ordovas JM, Ruilope LM, Lucia A (2021).

Lifestyle interventions for the prevention and treatment of hypertension.

NATURE REVIEWS CARDIOLOGY. Review. 18(4):251-275.
[doi:10.1038/s41569-020-00437-9]
Vázquez-Sánchez S, Poveda J, Navarro-García JA, González-Lafuente L, Rodríguez-Sánchez E, Ruilope LM, Ruiz-Hurtado G (2021).

An Overview of FGF-23 as a Novel Candidate Biomarker of Cardiovascular Risk.

Frontiers in Physiology. Review. 12:632260-632260.
[doi:10.3389/fphys.2021.632260]
Pappaccogli M, Di Monaco S, Warchol-Celinska E, Lorthioir A, Amar L, Aparicio LS, Beauloye C, Bruno RM, Chenu P, de Leeuw P, De Backer T, Delmotte P, Dika Z, Gordin D, Heuten H, Iwashima Y, Krzesinski JM, Kroon AA, Mazzolai L, Poch E, Sarafidis P, Seinturier C, Spiering W, Toubiana L, Van der Niepen P, van Twist D, Visonà A, Wautrecht JC, Witowicz H, Xu J, Prejbisz A, Januszewicz A, Azizi M, Persu A (2021).

The European/International Fibromuscular Dysplasia Registry and Initiative (FEIRI)-clinical phenotypes and their predictors based on a cohort of 1000 patients.

CARDIOVASCULAR RESEARCH. Article. 117(3):950-959.
[doi:10.1093/cvr/cvaa102]
Estruch, R, Ruilope, LM, Cosentino, F (2021).

The year in cardiovascular medicine 2020: epidemiology and prevention

EUROPEAN HEART JOURNAL. Article. 42(8):813-821.
[doi:10.1093/eurheartj/ehaa1062]
Filippatos G, Anker SD, Agarwal R, Pitt B, Ruilope LM, Rossing P, Kolkhof P, Schloemer P, Tornus I, Joseph A, Bakris GL, FIDELIO-DKD Investigators (2021).

Finerenone and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Type 2 Diabetes.

CIRCULATION. Article. 143(6):540-552.
[doi:10.1161/CIRCULATIONAHA.120.051898]
Fernández-Labandera C, Calvo-Bonacho E, Valdivielso P, Quevedo-Aguado L, Martínez-Munoz P, Catalina-Romero C, Ruilope LM, Sánchez-Chaparro MA (2021).

Prediction of fatal and non-fatal cardiovascular events in young and middle-aged healthy workers: The IberScore model

European Journal of Preventive Cardiology. Article. 28(2):177-186.
[doi:10.1177/2047487319894880]
de la Sierra, A, Mateu, A, Gorostidi, M, Vinyoles, E, Segura, J, Ruilope, LM (2021).

Antihypertensive therapy and short-termblood pressure variability

JOURNAL OF HYPERTENSION. Article. 39(2):349-355.
[doi:10.1097/HJH.0000000000002618]
Saco-Ledo G, Valenzuela PL, Castillo-García A, Arenas J, León-Sanz M, Ruilope LM, Lucia A (2021).

Physical exercise and epicardial adipose tissue: A systematic review and meta-analysis of randomized controlled trials.

OBESITY REVIEWS. Review. 22(1).
[doi:10.1111/obr.13103]
Gijón-Conde T, Rodilla E, Molinero A, Alvargonzález M, Ruilope LM (2021).

Conocimiento, tratamiento y control de la presión arterial según lugar de reclutamiento y sexo en la encuesta May Measure Month 2018 en España.

Hipertension y Riesgo Vascular. Article. 38(1):4-12.
[doi:10.1016/j.hipert.2020.07.003]

2020

Filippatos, G, Anker, SD, Agarwal, R, Pitt, B, Rossing, P, Ruilope, LM, Kolkhof, P, Schloemer, P, Tornus, I, Joseph, A, Bakris, GL (2020).

Finerenone and Cardiovascular Outcomes in Patients With Chronic Kidney Disease and Type 2 Diabetes

CIRCULATION. Meeting Abstract. 142(24):470-470.
Saco-Ledo, G, Valenzuela, PL, Ruiz-Hurtado, G, Ruilope, LM, Lucia, A (2020).

Exercise Reduces Ambulatory Blood Pressure in Patients With Hypertension: A Systematic Review and Meta-Analysis of Randomized Controlled Trials.

JOURNAL OF THE AMERICAN HEART ASSOCIATION. Review. 9(24).
[doi:10.1161/JAHA.120.018487]
Bakris, GL, Agarwal, R, Anker, SD, Pitt, B, Ruilope, LM, Rossing, P, Kolkhof, P, Nowack, C, Schloemer, P, Joseph, A, Filippatos, G, FIDELIO-DKD Investigators (2020).

Effect of Finerenone on Chronic Kidney Disease Outcomes in Type 2 Diabetes

NEW ENGLAND JOURNAL OF MEDICINE. Article. 383(23):2219-2229.
[doi:10.1056/NEJMoa2025845]
Utrero-Rico, A, Laguna-Goya, R, Cano-Romero, F, Chivite-Lacaba, M, Gonzalez-Cuadrado, C, Rodriguez-Sanchez, E, Ruiz-Hurtado, G, Serrano, A, Fernandez-Ruiz, M, Justo, I, Gonzalez, E, Andres, A, Paz-Artal, E (2020).

Early Posttransplant Mobilization of M-MDSC Correlates with Increase in Soluble Immunosuppressive Factors and Predicts Cancer in Kidney Recipients.

TRANSPLANTATION. Article. 104(12):2599-2608.
[doi:10.1097/TP.0000000000003179]
Böhm M, Schwantke, I, Mahfoud, F, Lauder, L, Wagenpfeil, S, de la Sierra, A, Vinyoles, E, Gorostidi, M, Segura, J, Ruilope, LM (2020).

Association of clinic and ambulatory heart rate parameters with mortality in hypertension.

JOURNAL OF HYPERTENSION. Article. 38(12):2416-2426.
[doi:10.1097/HJH.0000000000002565]
Ruilope LM, Ruiz-Hurtado G (2020).

Systemic lupus erythematosus and cardiovascular disease.

International Journal Cardiology Hypertension. Editorial Material. 7:100065-100065.
[doi:10.1016/j.ijchy.2020.100065]
Ruilope LM, Ruiz-Hurtado G (2020).

Age and blood pressure goal in women with prior coronary events.

International Journal Cardiology Hypertension. Editorial Material. 7:100059-100059.
[doi:10.1016/j.ijchy.2020.100059]
Ruilope LM, Ruiz-Hurtado G, Lucia A (2020).

Are the guidelines of the ISH devoted to a population not contemplated in the ACC/AHA guidelines?

International Journal Cardiology Hypertension. Editorial Material. 7:100068-100068.
[doi:10.1016/j.ijchy.2020.100068]
Rodríguez-Sánchez, E, Navarro-García, JA, González-Lafuente, L, Aceves-Ripoll, J, Vázquez-Sánchez, S, Poveda, J, Mercado-García, E, Corbacho-Alonso, N, Calvo-Bonacho, E, Fernández-Velasco, M, Alvarez-Llamas, G, Barderas, MG, Ruilope, LM, Ruiz-Hurtado, G (2020).

Oxidized Low-Density Lipoprotein Associates with Ventricular Stress in Young Adults and Triggers Intracellular Ca(2+) Alterations in Adult Ventricular Cardiomyocytes.

Antioxidants. Article. 9(12).
[doi:10.3390/antiox9121213]
Gil-Fernández, M, Navarro-García, JA, Val-Blasco, A, González-Lafuente, L, Martínez, JC, Rueda, A, Tamayo, M, Morgado, JL, Zaragoza, C, Ruilope, LM, Delgado, C, Ruiz-Hurtado, G, Fernández-Velasco, M (2020).

Genetic Deletion of NOD1 Prevents Cardiac Ca(2+) Mishandling Induced by Experimental Chronic Kidney Disease.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 21(22).
[doi:10.3390/ijms21228868]
Martinez, PJ, Agudiez, M, Molero, D, Martin-Lorenzo, M, Baldan-Martin, M, Santiago-Hernandez, A, García-Segura, JM, Madruga, F, Cabrera, M, Calvo, E, Ruiz-Hurtado, G, Barderas, MG, Vivanco, F, Ruilope, LM, Alvarez-Llamas, G (2020).

Urinary metabolic signatures reflect cardiovascular risk in the young, middle-aged, and elderly populations.

JOURNAL OF MOLECULAR MEDICINE-JMM. Article. 98(11):1603-1613.
[doi:10.1007/s00109-020-01976-x]
Navarro-García, JA, Rueda, A, Romero-García, T, Aceves-Ripoll, J, Rodríguez-Sánchez, E, González-Lafuente, L, Zaragoza, C, Fernández-Velasco, M, Kuro-o, M, Ruilope, LM, Ruiz-Hurtado, G (2020).

Enhanced Klotho availability protects against cardiac dysfunction induced by uraemic cardiomyopathy by regulating Ca(2+) handling.

BRITISH JOURNAL OF PHARMACOLOGY. Article. 177(20):4701-4719.
[doi:10.1111/bph.15235]
Ruilope, LM, Ruiz-Hurtado, G (2020).

Management of hypertension in the very old: aggressive reduction of blood pressure is harmful in most patients.

JOURNAL OF HUMAN HYPERTENSION. Review. 34(8):557-559.
[doi:10.1038/s41371-020-0346-0]
Beaney T, Schutte AE, Stergiou GS, Borghi C, Burger D, Charchar F, Cro S, Diaz A, Damasceno A, Espeche W, Jose AP, Khan N, Kokubo Y, Maheshwari A, Marin MJ, More A, Neupane D, Nilsson P, Patil M, Prabhakaran D, Ramirez A, Rodriguez P, Schlaich M, Steckelings UM, Tomaszewski M, Unger T, Wainford R, Wang J, Williams B, Poulter NR, MMM Investigators* (2020).

May Measurement Month 2019: The Global Blood Pressure Screening Campaign of the International Society of Hypertension.

HYPERTENSION. Article. 76(2):333-341.
[doi:10.1161/HYPERTENSIONAHA.120.14874]
Rodilla, E, Molinero, A, Gijón-Conde, T, Tous, S, Fornós, JA, Mera, I, Martínez, F, Carreras, B, de Berardinis, B, Beaney, T, Ster, AC, Poulter, NR, Xia, X, Ruilope, LM (2020).

May Measurement Month 2018: an analysis of blood pressure screening results from Spain.

EUROPEAN HEART JOURNAL SUPPLEMENTS. Article. 22(Suppl H):119-121.
[doi:10.1093/eurheartj/suaa044]
Rodriguez-Leor, O, Segura, J, Donaire, JAG, Gutierrez-Ibanes, E, Oliveras, A, Mediavilla, JD, Serrador, A, Prado, JC, Nunez-Gil, I, Diez-Delhoyo, F, Velasco, AC, Aguila, FJ, Amat-Santos, I, Bayes-Genis, A, Saborido, MIT (2020).

Renal denervation for the treatment of resistant hypertension in Spain. The Flex-Spyral Registry

REVISTA ESPANOLA DE CARDIOLOGIA. Article. 73(8):615-622.
[doi:10.1016/j.recesp.2019.05.013]
Rossignol, P, Ruilope, LM, Cupisti, A, Ketteler, M, Wheeler, DC, Pignot, M, Cornea, G, Schulmann, T, Lund, LH (2020).

Recurrent hyperkalaemia management and use of renin-angiotensin-aldosterone system inhibitors: a European multi-national targeted chart review

Clinical Kidney Journal. Letter. 13(4):714-719.
[doi:10.1093/ckj/sfz129]
Ruilope LM, Garcia Donaire JA, de la Sierra A (2020).

Bloqueantes del sistema renina-angiotensina e infección por COVID-19.

Hipertension y Riesgo Vascular. Editorial Material. 37(3):99-100.
[doi:10.1016/j.hipert.2020.04.002]
Divison-Garrote, JA, de la Cruz, JJ, de la Sierra, A, Vinyoles, E, Gorostidi, M, Escobar-Cervantes, C, Segura, J, Barrios, V, Ruilope, LM, Banegas, JR (2020).

Prevalence of office and ambulatory hypotension in treated hypertensive patients with coronary disease.

HYPERTENSION RESEARCH. Article. 43(7):696-704.
[doi:10.1038/s41440-020-0462-9]
Santiago-Hernandez, A, Martinez, PJ, Martin-Lorenzo, M, Ruiz-Hurtado, G, G Barderas M, Segura, J, Ruilope, LM, Alvarez-Llamas, G (2020).

Differential metabolic profile associated with the condition of normoalbuminuria in the hypertensive population.

NEFROLOGIA. Article. 40(4):440-445.
[doi:10.1016/j.nefro.2019.10.007]
Tamayo, M, Martín-Nunes, L, Val-Blasco, A, G M-Piedras MJ, Navarro-García, JA, Lage, E, Prieto, P, Ruiz-Hurtado, G, Fernández-Velasco, M, Delgado, C (2020).

Beneficial effects of paricalcitol on cardiac dysfunction and remodelling in a model of established heart failure.

BRITISH JOURNAL OF PHARMACOLOGY. Article. 177(14):3273-3290.
[doi:10.1111/bph.15048]
Ruilope, LM, Rodríguez-Sánchez, E, Navarro-García, JA, Segura, J, Ortiz, A, Lucia, A, Ruiz-Hurtado, G (2020).

Resistant hypertension: new insights and therapeutic perspectives.

European Heart Journal-Cardiovascular Pharmacotherapy. Review. 6(3):188-193.
[doi:10.1093/ehjcvp/pvz057]
Corbacho-Alonso, N, Baldán-Martín, M, López, JA, Sánchez, ER, Martínez, PJ, Mourino-Alvarez, L, Martin-Rojas, T, Sastre-Oliva, T, Madruga, F, Vázquez, J, Padial, LR, Alvarez-Llamas, G, Vivanco, F, Ruiz-Hurtado, G, Ruilope, LM, Barderas, MG (2020).

Novel molecular plasma signatures on cardiovascular disease can stratify patients throughout life.

JOURNAL OF PROTEOMICS. Article. 222:103816-103816.
[doi:10.1016/j.jprot.2020.103816]
Mahfoud, F, Mancia, G, Schmieder, R, Narkiewicz, K, Ruilope, L, Schlaich, M, Whitbourn, R, Zirlik, A, Zeller, T, Stawowy, P, Cohen, SA, Fahy, M, Böhm M (2020).

Renal Denervation in High-Risk Patients With Hypertension.

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Article. 75(23):2879-2888.
[doi:10.1016/j.jacc.2020.04.036]
Ruilope, LM, Tamargo, J, Ruiz-Hurtado, G (2020).

Renin-angiotensin system inhibitors in the COVID-19 pandemic: consequences of antihypertensive drugs.

EUROPEAN HEART JOURNAL. Editorial Material. 41(22):2067-2069.
[doi:10.1093/eurheartj/ehaa487]
Battistoni, A, Tocci, G, Coluccia, R, Burnier, M, Ruilope, LM, Volpe, M (2020).

Antihypertensive drugs and the risk of cancer: a critical review of available evidence and perspective.

JOURNAL OF HYPERTENSION. Review. 38(6):1005-1015.
[doi:10.1097/HJH.0000000000002379]
Sarafidis, P, Loutradis, C, Ortiz, A, Ruilope, LM (2020).

Blood pressure targets in patients with chronic kidney disease: MDRD and AASK now confirming SPRINT.

Clinical Kidney Journal. Editorial Material. 13(3):287-290.
[doi:10.1093/ckj/sfaa015]
Soldevila, N, Vinyoles, E, Tobias, A, Banegas, JR, De La Sierra, A, Gorostidi, M, Segura, J, De La Cruz, JJ, Munoz-Perez, MA, Querol, X, Ruilope, LM (2020).

How do ultrafine particles in urban air affect ambulatory blood pressure?

JOURNAL OF HYPERTENSION. Article. 38(5):845-849.
[doi:10.1097/HJH.0000000000002343]
Mahfoud, F, Azizi, M, Ewen, S, Pathak, A, Ukena, C, Blankestijn, PJ, Bohm, M, Burnier, M, Chatellier, G, Durand Zaleski I, Grassi, G, Joner, M, Kandzari, DE, Kirtane, A, Kjeldsen, SE, Lobo, MD, Lüscher, TF, McEvoy, JW, Parati, G, Rossignol, P, Ruilope, L, Schlaich, MP, Shahzad, A, Sharif, F, Sharp ASP, Sievert, H, Volpe, M, Weber, MA, Schmieder, RE, Tsioufis, C, Wijns, W (2020).

Proceedings from the 3rd European Clinical Consensus Conference for clinical trials in device-based hypertension therapies.

EUROPEAN HEART JOURNAL. Article. 41(16):1588-1599.
[doi:10.1093/eurheartj/ehaa121]
Valenzuela PL, Morales JS, Ruilope LM, de la Villa P, Santos-Lozano A, Lucia A (2020).

Intradialytic neuromuscular electrical stimulation improves functional capacity and muscle strength in people receiving haemodialysis: a systematic review.

Journal Of Physiotherapy. Review. 66(2):89-96.
[doi:10.1016/j.jphys.2020.03.006]
Rodríguez-Sánchez, E, Navarro-García, JA, Aceves-Ripoll, J, Abarca-Zabalía, J, Susmozas-Sánchez, A, Bada-Bosch, T, Hernández, E, Mérida-Herrero, E, Andrés, A, Praga, M, Fernández-Ruiz, M, Aguado, JM, Segura, J, Ruilope, LM, Ruiz-Hurtado, G (2020).

Variations in Circulating Active MMP-9 Levels During Renal Replacement Therapy.

Biomolecules. Article. 10(4).
[doi:10.3390/biom10040505]
Gil-Ortega, M, Vega-Martín, E, Martín-Ramos, M, González-Blázquez, R, Pulido-Olmo, H, Ruiz-Hurtado, G, Schulz, A, Ruilope, LM, Kolkhof, P, Somoza, B, Kreutz, R, Fernández-Alfonso, MS (2020).

Finerenone Reduces Intrinsic Arterial Stiffness in Munich Wistar Fromter Rats, a Genetic Model of Chronic Kidney Disease.

AMERICAN JOURNAL OF NEPHROLOGY. Article. 51(4):294-303.
[doi:10.1159/000506275]
Banegas JR, Ruilope LM, de la Sierra A, Vinyoles E, Gorostidi M, de la Cruz JJ, Ruiz-Hurtado G, Segura J, Rodriguez-Artalejo F, Williams B (2020).

Retraction: Banegas JR et al. Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality. N Engl J Med 2018;378:1509-20.

NEW ENGLAND JOURNAL OF MEDICINE. Letter. 382(8):786-786.
[doi:10.1056/NEJMc2001445]
Aguilar Del Rey J, Jódar Gimeno E, Brañas Baztán F, Gómez Alonso C, González Lama Y, Malouf Sierra J, Borrego RS, Segura de la Morena J, Suárez Pérez JA, Valdés Y Llorca C (2020).

Is vitamin-D supplementation not useful in patients at risk of fractures and falls?

GYNECOLOGICAL ENDOCRINOLOGY. Article. 36(2):1-3.
[doi:10.1080/09513590.2019.1650346]
Ruilope, LM, Rodriguez-Sanchez, E, Ruiz-Hurtado, G (2020).

On the need of the simultaneous control of arterial hypertension and diabetes mellitus.

Journal of Clinical Hypertension. Editorial Material. 22(2):221-222.
[doi:10.1111/jch.13794]
Perales, M, Valenzuela, PL, Barakat, R, Cordero, Y, Pelaez, M, Lopez, C, Ruilope, LM, Santos-Lozano, A, Lucia, A (2020).

Gestational Exercise and Maternal and Child Health: Effects until Delivery and at Post-Natal Follow-up.

Journal of Clinical Medicine. Article. 9(2).
[doi:10.3390/jcm9020379]
Valenzuela, PL, Ruilope, LM, Lucia, A (2020).

Muscling in on Resistant Hypertension.

CIRCULATION. Editorial Material. 141(4):240-242.
[doi:10.1161/CIRCULATIONAHA.119.044378]
Tamayo, M, Fulgencio-Covián, A, Navarro-García, JA, Val-Blasco, A, Ruiz-Hurtado, G, Gil-Fernández, M, Martín-Nunes, L, Lopez, JA, Desviat, LR, Delgado, C, Richard, E, Fernández-Velasco, M (2020).

Intracellular calcium mishandling leads to cardiac dysfunction and ventricular arrhythmias in a mouse model of propionic acidemia.

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR BASIS OF DISEASE. Article. 1866(1):165586-165586.
[doi:10.1016/j.bbadis.2019.165586]
Ruiz-Hurtado, G, Rueda, A, Pereira, L, Fernández-Velasco, M (2020).

Editorial: Evolving Picture of Calcium Handling in Cardiac Disease.

Frontiers in Physiology. Editorial Material. 11:1013-1013.
[doi:10.3389/fphys.2020.01013]

2019

Burnier, M, Lin, SY, Ruilope, L, Bader, G, Durg, S, Brunel, P (2019).

Effect of angiotensin receptor blockers on blood pressure and renal function in patients with concomitant hypertension and chronic kidney disease: a systematic review and meta-analysis.

BLOOD PRESSURE. Article. 28(6):358-374.
[doi:10.1080/08037051.2019.1644155]
Alexandrou ME, Papagianni A, Tsapas A, Loutradis C, Boutou A, Piperidou A, Papadopoulou D, Ruilope L, Bakris G, Sarafidis P (2019).

Effects of mineralocorticoid receptor antagonists in proteinuric kidney disease: a systematic review and meta-analysis of randomized controlled trials.

JOURNAL OF HYPERTENSION. Review. 37(12):2307-2324.
[doi:10.1097/HJH.0000000000002187]
Navarro-García, JA, Rodríguez-Sánchez, E, Aceves-Ripoll, J, Abarca-Zabalía, J, Susmozas-Sánchez, A, González Lafuente L, Bada-Bosch, T, Hernández, E, Mérida-Herrero, E, Praga, M, Ruilope, LM, Ruiz-Hurtado, G (2019).

Oxidative Status before and after Renal Replacement Therapy: Differences between Conventional High Flux Hemodialysis and on-Line Hemodiafiltration.

Nutrients. Article. 11(11).
[doi:10.3390/nu11112809]
Mahfoud F, Bohm, M, Schmieder R, Narkiewicz K, Ewen S, Ruilope L, Schlaich M, Williams B, Fahy M, Mancia G (2019).

Effects of renal denervation on kidney function and long-term outcomes: 3-year follow-up from the Global SYMPLICITY Registry.

EUROPEAN HEART JOURNAL. Article. 40(42):3474-3482.
[doi:10.1093/eurheartj/ehz118]
Navarro-García JA, Delgado C, Fernández-Velasco M, Val-Blasco A, Rodríguez-Sánchez E, Aceves-Ripoll J, Gómez-Hurtado N, Bada-Bosch T, Mérida-Herrero E, Hernández E, Praga M, Salguero R, Solís J, Arribas F, Delgado JF, Bueno H, Kuro-O M, Ruilope LM, Ruiz-Hurtado G (2019).

Fibroblast growth factor-23 promotes rhythm alterations and contractile dysfunction in adult ventricular cardiomyocytes.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 34(11):1864-1875.
[doi:10.1093/ndt/gfy392]
Ruilope, LM, Rodriguez-Sanchez, E, Ruiz-Hurtado, G (2019).

The endless story of markers of renal function and cardiovascular risk.

EUROPEAN HEART JOURNAL. Editorial Material. 40(42):3494-3495.
[doi:10.1093/eurheartj/ehz489]
Ruilope LM, Agarwal R, Anker SD, Bakris GL, Filippatos G, Nowack C, Kolkhof P, Joseph A, Mentenich N, Pitt B, FIGARO-DKD study investigators (2019).

Design and Baseline Characteristics of the Finerenone in Reducing Cardiovascular Mortality and Morbidity in Diabetic Kidney Disease Trial.

AMERICAN JOURNAL OF NEPHROLOGY. Article. 50(5):1-12.
[doi:10.1159/000503712]
Bakris, GL, Agarwal, R, Anker, SD, Pitt, B, Ruilope, LM, Nowack, C, Kolkhof, P, Ferreira, AC, Schloemer, P, Filippatos, G, on behalf of the FIDELIO-DKD study investigators (2019).

Design and Baseline Characteristics of the Finerenone in Reducing Kidney Failure and Disease Progression in Diabetic Kidney Disease Trial.

AMERICAN JOURNAL OF NEPHROLOGY. Article. 50(5):1-12.
[doi:10.1159/000503713]
RodrÍguez-SÁnchez E, Navarro-GarcÍa JA, Aceves-Ripoll J, GonzÁlez-Lafuente L, Corbacho-Alonso N, Martinez P, Calvo-Bonacho E, Alvarez-Llamas G, Barderas MG, Ruilope LM, Ruiz-Hurtado G (2019).

Lifetime cardiovascular risk is associated with a multimarker score of systemic oxidative status in young adults independently of traditional risk factors.

TRANSLATIONAL RESEARCH. Article. 212:54-66.
[doi:10.1016/j.trsl.2019.06.002]
Gijón-Conde T, Gorostidi M, Banegas JR, de la Sierra A, Segura J, Vinyoles E, Divisón-Garrote JA, Ruilope LM (2019).

Documento de la Sociedad Española de Hipertensión-Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA) sobre monitorización ambulatoria de la presión arterial (MAPA) 2019.

Hipertension y Riesgo Vascular. Article. 36(4):199-212.
[doi:10.1016/j.hipert.2019.05.002]
Scurt, FG, Menne, J, Brandt, S, Bernhardt, A, Mertens, PR, Haller, H, Chatzikyrkou, C, Ito, S, Izzo, JL, Januszewicz, A, Katayama, S, Mimram, A, Rabelink, TJ, Ritz, E, Ruilope, LM, Rump, LC, Viberti, G, Haller, H, ROADMAP Steering Comm (2019).

Systemic Inflammation Precedes Microalbuminuria in Diabetes

Kidney International Reports. Article. 4(10):1373-1386.
[doi:10.1016/j.ekir.2019.06.005]
Márquez DF, Ruiz-Hurtado G, Segura J, Ruilope L (2019).

Microalbuminuria and cardiorenal risk: old and new evidence in different populations.

F1000research. Article. 8.
[doi:10.12688/f1000research.17212.1]
Ruilope, LM, Ruiz-Hurtado, G (2019).

Monotherapy still useful in a bunch of patients with arterial hypertension

International Journal of Cardiology. Editorial Material. 291:119-120.
[doi:10.1016/j.ijcard.2019.05.057]
Cortés Fernández MDS, Segura J (2019).

Urgencias hipertensivas ¿se han de tratar todas igual?

Hipertension y Riesgo Vascular. Article. 36(3):119-121.
[doi:10.1016/j.hipert.2019.05.004]
Ruilope, LM, Ruiz-Hurtado, G, Barderas, MG, de la Cruz, JJ, Lucia, A, de la Sierra, A, Gorostidi, M, Vinyoles, E, Segura, J, Solís, J, Arribas, F, García-Puig, J, Tamargo, J, O'Brien, E, Volpe, M, Whelton, PK, Williams, B, Banegas, JR (2019).

Frequency and Prognosis of Treated Hypertensive Patients According to Prior and New Blood Pressure Goals.

HYPERTENSION. Article. 74(1):130-136.
[doi:10.1161/HYPERTENSIONAHA.119.12921]
Corbacho-Alonso N, Rodríguez-Sánchez E, Martin-Rojas T, Mouriño-Alvarez L, Sastre-Oliva T, Hernandez-Fernandez G, Padial LR, Ruilope LM, Ruiz-Hurtado G, Barderas MG (2019).

Proteomic investigations into hypertension: what's new and how might it affect clinical practice?

Expert Review of Proteomics. Review. 16(7):583-591.
[doi:10.1080/14789450.2019.1632197]
Beaney T, Burrell LM, Castillo RR, Charchar FJ, Cro S, Damasceno A, Kruger R, Nilsson PM, Prabhakaran D, Ramirez AJ, Schlaich MP, Schutte AE, Tomaszewski M, Touyz R, Wang JG, Weber MA, Poulter NR, MMM Investigators (2019).

May Measurement Month 2018: a pragmatic global screening campaign to raise awareness of blood pressure by the International Society of Hypertension.

EUROPEAN HEART JOURNAL. Article. 40(25):2006-2017.
[doi:10.1093/eurheartj/ehz300]
Verma, S, Wanner, C, Zwiener, I, Ofstad, AP, George, JT, Fitchett, D, Zinman, B, Aizenberg, D, Ulla, M, Waitman, J, De Loredo, L, Farias, J, Fideleff, H, Lagrutta, M, Maldonado, N, Colombo, H, Pacora, FF, Wasserman, A, Maffei, L, Lehman, R, Selvanayagam, J, d'Emden, M, Fasching, P, Paulweber, B, Toplak, H, Luger, A, Drexel, H, Prager, R, Schnack, C, Schernthaner, G, Fliesser-Gorzer, E, Kaser, S, Scheen, A, Van Gaal, L, Hollanders, G, Kockaerts, Y, Capiau, L, Chachati, A, Persu, A, Hermans, M, Vantroyen, D, Vercammen, C, Van de Borne, P, Mathieu, C, Benhalima, K, Lienart, F, Mortelmans, J, Strivay, M, Vereecken, G, Keymeulen, B, Lamkanfi, F, Chacra, A, Eliaschewitz, F, Zanella, M, Faludi, A, Bertolami, M, Hayashida, C, Salles, JN, Monte, O, Dinato, M, Manenti, E, Rassi, N, Halpern, A, Lima, M, Ayoub, J, Felicio, J, Borges, J, Gross, J, Sgarbi, J, Betti, R, Tiburcio, A, Purisch, S, Schmid, H, Takahashi, M, Castro, M, Rea, R, Hissa, M, Neto, BG, Saraiva, J, Henein, S, Lochnan, H, Imran, SA, Clayton, D, Bayly, K, Berlingieri, J, Boucher, P, Chan, Y, Gupta, M, Chehayeb, R, Ouellett, A, Ur, E, Woo, V, Zinman, B, St Amour, E, Lozano, MT, Lozno, HY, Urina, M, Jaramillo, PL, Jaramillo, N, Sanchez, G, Perez, G, Tusek, S, Mirosevic, G, Goldoni, V, Jurisic-Erzen, D, Balasko, A, Balic, S, Drvodelic-Sunic, E, Varzic, SC, Machkova, M, Weiner, P, Lastuvka, J, Olsovsky, J, Krarup, T, Ridderstrale, M, Tarnow, L, Boesgaard, TW, Lihn, AS, Christensen, P, Juhl, H, Urhammer, S, Lund, P, Adojaan, B, Jakovlev, U, Lanno, R, Lubi, M, Marandi, T, Gouet, D, Courreges, J, Zaoui, P, Choukroun, G, Petit, C, Formagne, L, Estour, B, Mabire, P, Daugenet, C, Lemarie, B, Clavel, S, Aure, P, Remaud, P, Halimi, J, Hadjadj, S, Couffinhal, T, Glonti, S, Metreveli, D, Lominadze, Z, Giorgadze, E, Burtchuladze, T, Javashvili, L, Kurashvili, G, Kurashvili, R, Virsaladze, D, Nadareishvili, L, Khomasuridze, A, Cahill, T, Green, F, MacRury, S, Waldron, M, Middleton, A, McKnight, J, Pearson, E, Butler, M, Choksi, M, Caldwell, I, Farmer, I, Wyatt, N, Patrick, J, O'Brien, I, Devers, M, Bousboulas, S, Pappas, S, Piaditis, G, Vryonidou, A, Tentolouris, N, Karamitsos, K, Manes, C, Benroubi, M, Avramidis, I, Ozaki, R, Tan, K, Siu, S, Tsang, C, Dudas, M, Nagy, K, Salamon, C, Ip, T, Geroo, L, Patkay, J, Tabak, A, Juhasz, F, Szentpeteri, I, Tamas, G, Ghaisas, N, Bantwal, G, Mohan, V, Gupta, J, Sadhu, N, Kulkarni, A, Garg, N, Reddy, S, Deshpande, N, Gutlapalli, K, Pillai, M, Premchand, R, Badgandi, M, Jain, S, Aravind, S, Shamanna, P, Pandey, A, Gupta, S, Pramono, B, Saksono, HD, Agung, P, Wahono, SD, Suastika, K, Tanggo, Y, Juwana, Y, Siswanto, B, Adawi, F, Efrati, S, Mazen, E, Bashkin, A, Herskovits, T, Jaffe, A, Schiff, E, Wainstein, J, Taddei, S, Aiello, A, Arca, M, Calabro, P, Cignarelli, M, Fioretto, P, Reggiani, GM, Gnasso, A, Marchionni, N, Marsilii, A, Bucci, M, Mezzetti, A, Pozzilli, P, Colivicchi, F, Santini, M, Moro, E, Toscano, V, Fucili, A, Semplicini, A, Monno, S, Furui, K, Higashiue, S, Hiramatsu, N, Kawamitsu, K, Takenaka, T, Takahashi, H, Hojo, F, Onishi, Y, Izumino, K, Okubo, M, Wakida, Y, Kondo, Y, Hieshima, K, Jinnouchi, H, Suzuki, A, Ito, M, Park, S, Kim, Y, Hong, T, Park, H, Gwon, H, Kim, H, Kang, K, Jeong, M, Seung, K, Lim, D, Rha, S, Tahk, S, Yang, J, Yoon, J, Shin, M, Kim, D, Jeong, J, Ahmad, NN, Mustafa, N, Mohamed, WW, Fung, Y, Ghani, RA, Chandramouli, A, Chee, K, Kadir, KA, Ling, K, Abu Hassan, M, Foo, S, Lee, S, Hernandez, PG, Aguilar-Salinas, C, Velazquez, MV, Flores, F, Salazar, MA, Escalante, DM, Soria, MG, Munoz, EC, Storms, G, Schaper, N, Kooy, A, Krekels, M, van Bemmel, T, Verhoeven, R, Mulder, H, Oldenburg-Ligtenberg, P, Gonkel, F, de Jong, A, van Soest, J, Viergever, P, Mevissen, H, Lochorn, G, Zwiers, G, Hoogslag, P, Ronner, E, Nierop, P, Al-Windy, N, Kragten, J, Dekelver, P, Benatar, J, Krebs, J, Scott, R, Heggen, E, Berz, A, Fossum, C, Hurtig, U, Langslet, G, Baranowski, M, Sparby, J, Karlsson, T, Karlsson, T, Torres, CD, Escudero, AR, Lisson, R, Maldonado, AA, Rojas, WG, Bravo, LG, Osores, JL, Farfan, J, Zapata, L, Junchaya, JG, Concha, YR, Calderon, JU, Sy, R, Tan, G, Aquitania, G, De Los Santos, G, Panelo, A, Roderos, O, Rosales, R, Toledo, R, Liwag, A, Ramoncito, H, Skokowska, E, Krzyzagorska, E, Ogorek, M, Wojnowski, L, Spyra, J, Konieczny, M, Piesiewicz, W, Kus, W, Ocicka-Kozakiewicz, A, Orlowska-Kunikowska, E, Zmuda, W, Duarte, S, Leitao, A, Monteiro, P, Rita, H, Salgado, V, Pinto, L, Queiros, J, Teixeira, J, Rogado, C, Duarte, R, do Rosario, FS, Silva, A, Andrade, L, Velez, M, Brazao, M, Istratoaie, O, Lichiardopol, R, Catrinoiu, D, Militaru, C, Zetu, C, Barbonta, D, Cosma, D, Crisan, C, Pop, L, Esip, V, Khetagurova, F, Petrov, A, Arutyunov, G, Boyarkin, M, Agafyina, A, Vorokhobina, N, Petunina, N, Libov, I, Zalevskaya, A, Nikolaev, K, Barbarash, O, Potemkin, V, Bystrova, A, Krasilnikova, E, Barbarich, V, Chumakova, G, Tarasov, N, Meleshkevich, T, Zateyshchikov, D, Lantseva, O, Belenkiy, D, Obrezan, A, Rossolko, L, Fillipova, E, Yakhontova, P, Khokhlov, A, Tan, R, Sum, C, Chang, H, Distiller, L, Pretorius, M, Nortje, H, Mitha, E, Burgess, L, Blignaut, S, Venter, T, Moodley, R, Lombaard, J, Govind, U, Naidoo, V, Mookadam, M, Engelbrecht, J, Omar, M, Jurgens, J, Podgorski, G, Vawda, H, Naidoo, D, Emanuel, S, Roodt, A, Amod, A, Van Zyl, L, Segura, J, Brito, M, Fernandez-Cruz, A, Artola, S, Iglesias, R, Toural, E, Garcia-Ortiz, L, Saban, J, Mesa, J, Vidal, J, Linares, J, del Canizo, F, Rigla, M, Suarez, C, Llorente, I, Moreno, B, Antoli, A, Peralta, FG, Iglesias, M, Pereg, V, de Teresa, L, Camafort, M, Trescoli, C, Satarasinghe, R, Somasundaram, N, Siyambalapitiya, S, Antonypillai, C, Bulugahapitiya, D, Medagama, U, Huang, C, Lu, Y, Hwang, J, Chiang, C, Wen, M, Chen, J, Lai, W, Chang, K, Wang, J, Yeh, H, Kriangsak, P, Deerochanawong, C, Suwanwalaikorn, S, Mangklabruks, A, Kaewsuwanna, P, Piyayotai, D, Iabluchanskyi, M, Samoylov, O, Godlevska, O, Kovalyova, O, Voloshyna, O, Tseluyko, V, Zotov, S, Vykhovanyuk, I, Dulgeroff, A, Mayfield, R, Zaniewski-Singh, M, Ullal, J, Aloi, J, De La Rosa, R, Mosely, J, Wittmer, B, Aronoff, S, Rosenfeld, J, Seidner, M, Warren, M, Fishman, N, Weiss, R, Arif, A, Sandberg, M, Lewis, D, Ball, E, Graf, R, Breton, C, Tamayo, R, Richards, R, Cefalu, W, Uwaifo, G, Zayour, D, Hoffman, J, Fitz-Patrick, D, Khan, B, Blaze, K, Bressler, P, Halpern, S, Chappell, D, Bergenstal, R, Cuddihy, R, Matfin, G, Freedman, Z, Gonzalez-Campoy, J, Lerman, S, Rendell, M, Sitar, S, Reeves, M, Howard, T, Soufer, J, Miranda-Palma, B, Laliotis, A, Shomali, M, Teltser, M, Hurley, D, Morawski, E, Cherlin, R, Houchin, V, Welch, M, Goytia-Leos, D, Syed, M, Kowaloff, E, Weinrauch, L, Peniston, J, Brockmyre, A, First, B, Feld, L, Huffman, D, Nassim, O, Gottschlich, G, Patel, A, Knopke, C, Hernandez, M, Diaz, J, Giugliano, G, Nicasio, J, Eagerton, D, Huntley, R, Reed, J, Magee, M, Hippert, R, Sofley, C, Alzohaili, O, Levins, P, Anspach, R, Shah, S, Brusco, O, Naidu, J, Lindenbaum, J, Jacks, R, Hammond, G, Arena, C, Saxman, K, Mach, M, Kerstein, H, Kereiakes, D, Wahlen, J, Wehmeier, K, Chaykin, L, Rothman, J, Fogelfeld, L, Stroger, JH, Bittar, N, Rosenstock, J, Kayne, D, Navarro, J, Colfer, H, Mokshagundam, S, Shandilya, L, Connery, L, Wysham, C, Dela Llana, A, Jardula, M, MacAdams, M, Flippo, G, Heurich, E, Curtis, C, Sanders, D, Rawls, R, Velazquez, F, Osea, E, Mahood, K, Feldman, G, Eder, F, Riley, E, Fowler, W, Jain, M, Shepard, M, Schear, M, Barker, B, Strout, C, Obiekwe, O, Shanik, M, Green, C, Blakney, E, Roberson, K, Bretton, E, Pish, R, Kaveh, K, Maynard, B, Barager, W, Soldyshev, R, Austin, B, Parmar, P, Simpson, R, Chauhan, A, Kasper, J, Burr, R, Patel, N, Mariano, H, Pluto, T, Bratcher, C, Juarez, M, Levinson, L, Awad, A, Longshaw, K, Hoffman, K, Richwine, R, Molter, D, Boscia, J, Kowalyk, S, Lemis, P, Liss, J, Orr, R, Riser, J, Wood, J, Ubani, A, Paine, W, Hassani, F, Miranda, F, Hansen, V, Hansen, VR, Farris, N, Bowden, R, Ajani, D, Maw, K, Andersen, J, Bergman, B, Dunmyer, S, Brandon, D, Anderson, M, Bononi, P, Prawer, J, Seidman, B, Cruz, H, Wilks, K, DiSanto, L, Buynak, R, Christensen, T, Denker, P, Koppel, W, Stedman, M, Lewy-Alterbaum, L, Karim, S, Shapiro, J, Gardner, T, Oskin, T, Gabra, N, Malano, J, EMPA-REG OUTCOME Investigators (2019).

Influence of Microvascular Disease on Cardiovascular Events in Type 2 Diabetes

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Letter. 73(21):2780-2782.
[doi:10.1016/j.jacc.2019.03.002]
Ruilope, LM, Ruiz-Hurtado, G (2019).

Impact of the new USA and ESC/ESH HTN guidelines for Spain.

EUROPEAN HEART JOURNAL. Editorial Material. 40(21):1660-1661.
[doi:10.1093/eurheartj/ehz345]
Molinero, A, Ruilope, LM, Tous, S, Fornos, JA, Mera, I, Andres, NF, Iracheta, M, Xia, X, Beaney, T, Poulter, NR, Rodilla, E, Martinez, F, Gijon-Conde, T (2019).

May Measurement Month 2017: an analysis of blood pressure screening in Spain-Europe.

EUROPEAN HEART JOURNAL SUPPLEMENTS. Article. 21(Suppl D):107-110.
[doi:10.1093/eurheartj/suz070]
Catalina-Romero C, Sanchez Chaparro MA, Valdivielso P, Quevedo-Aguado L, Brotons C, Ruilope LM, Calvo-Bonacho E (2019).

Estimating the impact of obesity and metabolic phenotype on sickness absence. Results from the ICARIA study.

NUTRITION METABOLISM AND CARDIOVASCULAR DISEASES. Article. 29(4):383-389.
[doi:10.1016/j.numecd.2018.12.005]
Yakhine-Diop SMS, Niso-Santano, M, Rodriguez-Arribas, M, Gomez-Sanchez, R, Martinez-Chacon, G, Uribe-Carretero, E, Navarro-Garcia, JA, Ruiz-Hurtado, G, Aiastui, A, Cooper, JM, Lopez de Munain A, Bravo-San Pedro, JM, Gonzalez-Polo, RA, Fuentes, JM (2019).

Impaired Mitophagy and Protein Acetylation Levels in Fibroblasts from Parkinson's Disease Patients.

MOLECULAR NEUROBIOLOGY. Article. 56(4):2466-2481.
[doi:10.1007/s12035-018-1206-6]
Martin-Lorenzo M, Martinez PJ, Baldan-Martin M, Lopez JA, Minguez P, Santiago-Hernandez A, Vazquez J, Segura J, Ruiz-Hurtado G, Vivanco F, Barderas MG, Ruilope LM, Alvarez-Llamas G (2019).

Urine Haptoglobin and Haptoglobin-Related Protein Predict Response to Spironolactone in Patients With Resistant Hypertension.

HYPERTENSION. Article. 73(4):794-802.
[doi:10.1161/HYPERTENSIONAHA.118.12242]
Rossignol P, Agarwal, R, Canaud, B, Charney, A, Chatellier, G, Craig, JC, Cushman, WC, Gansevoort, RT, Fellström B, Garza, D, Guzman, N, Holtkamp, FA, London, GM, Massy, ZA, Mebazaa, A, Mol PGM, Pfeffer, MA, Rosenberg, Y, Ruilope, LM, Seltzer, J, Shah, AM, Shah, S, Singh, B, Stefansson, BV, Stockbridge, N, Stough, WG, Thygesen, K, Walsh, M, Wanner, C, Warnock, DG, Wilcox, CS, Wittes, J, Pitt, B, Thompson, A, Zannad, F (2019).

Cardiovascular outcome trials in patients with chronic kidney disease: challenges associated with selection of patients and endpoints.

EUROPEAN HEART JOURNAL. Article. 40(11):880-886.
[doi:10.1093/eurheartj/ehx209]
Martínez PJ, Baldán-Martín M, López JA, Martín-Lorenzo M, Santiago-Hernández A, Agudiez M, Cabrera M, Calvo E, Vázquez J, Ruiz-Hurtado G, Vivanco F, Ruilope LM, Barderas MG, Alvarez-Llamas G (2019).

Identification of six cardiovascular risk biomarkers in the young population: A promising tool for early prevention

ATHEROSCLEROSIS. Article. 282:67-74.
[doi:10.1016/j.atherosclerosis.2019.01.003]
Rodríguez-Sánchez E, Navarro-García JA, Aceves-Ripoll J, Álvarez-Llamas G, Segura J, Barderas MG, Ruilope LM, Ruiz-Hurtado G (2019).

Association between renal dysfunction and metalloproteinase (MMP)-9 activity in hypertensive patients

NEFROLOGIA. Article. 39(2):184-191.
[doi:10.1016/j.nefro.2018.08.009]
Delgado, C, Gomez, AM, Samia El Hayek M, Ruiz-Hurtado, G, Pereira, L (2019).

Gender-Dependent Alteration of Ca(2+)and TNF alpha Signaling in db/db Mice, an Obesity-Linked Type 2 Diabetic Model

Frontiers in Physiology. Article. 10:40-40.
[doi:10.3389/fphys.2019.00040]
Ruilope, LM, Ruiz-Hurtado, G (2019).

New vascular biomarkers related to ABPM phenotypes in untreated patients

Journal of Clinical Hypertension. Editorial Material. 21(1):53-54.
[doi:10.1111/jch.13445]
van den Born, BJH, Lip GYH, Brguljan-Hitij, J, Cremer, A, Segura, J, Morales, E, Mahfoud, F, Amraoui, F, Persu, A, Kahan, T, Agabiti Rosei E, de Simone, G, Gosse, P, Williams, B (2019).

ESC Council on hypertension position document on the management of hypertensive emergencies

European Heart Journal-Cardiovascular Pharmacotherapy. Article. 5(1):37-46.
[doi:10.1093/ehjcvp/pvy032]
Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I (2019).

[2018 ESC/ESH Guidelines for the management of arterial hypertension].

POLISH HEART JOURNAL-KARDIOLOGIA POLSKA. Article. 77(2):71-159.
[doi:10.5603/KP.2019.0018]

2018

Williams, B, Mancia, G, Spiering, W, Agabiti Rosei E, Azizi, M, Burnier, M, Clement, D, Coca, A, De Simone, G, Dominiczak, A, Kahan, T, Mahfoud, F, Redon, J, Ruilope, L, Zanchetti, A, Kerins, M, Kjeldsen, S, Kreutz, R, Laurent, S, Lip GYH, McManus, R, Narkiewicz, K, Ruschitzka, F, Schmieder, R, Shlyakhto, E, Tsioufis, K, Aboyans, V, Desormais, I, List of authors/Task Force members: (2018).

2018 Practice Guidelines for the management of arterial hypertension of the European Society of Cardiology andthe European Society of Hypertension ESC/ESH Task Force for the Management of Arterial Hypertension

JOURNAL OF HYPERTENSION. Article. 36(12):2284-2309.
[doi:10.1097/HJH.0000000000001961]
Williams, B, Mancia, G, Spiering, W, Agabiti Rosei E, Azizi, M, Burnier, M, Clement, D, Coca, A, De Simone, G, Dominiczak, A, Kahan, T, Mahfoud, F, Redon, J, Ruilope, L, Zanchetti, A, Kerins, M, Kjeldsen, S, Kreutz, R, Laurent, S, Lip GYH, McManus, R, Narkiewicz, K, Ruschitzka, F, Schmieder, R, Shlyakhto, E, Tsioufis, K, Aboyans, V, Desormais, I (2018).

2018 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC)

BLOOD PRESSURE. Article. 27(6):314-340.
[doi:10.1080/08037051.2018.1527177]
Williams B, Mancia G, Spiering W, Rosei EA, Azizi M, Burnier M, Clement DL, Coca A, de Simone G, Dominiczak A, Kahan T, Mahfoud F, Redon J, Ruilope L, Zanchetti A, Kerins M, Kjeldsen SE, Kreutz R, Laurent S, Lip GYH, McManus R, Narkiewicz K, Ruschitzka F, Schmieder RE, Shlyakhto E, Tsioufis C, Aboyans V, Desormais I (2018).

[2018 ESC/ESH Guidelines for the management of arterial hypertension. The Task Force for the management of arterial hypertension of the European Society of Cardiology (ESC) and the European Society of Hypertension (ESH)].

Giornale Italiano di Cardiologia. Abstract of Published Item. 19(11):3-73.
[doi:10.1714/3026.30245]
Gorostidi, M, Sanchez-Martinez, M, Ruilope, LM, Graciani, A, de la Cruz, JJ, Santamaria, R, del Pino, MD, Guallar-Castillon, P, de Alvaro, F, Rodriguez-Artalejo, F, Banegas, JR (2018).

Chronic kidney disease in Spain: Prevalence and impact of accumulation of cardiovascular risk factorsN

NEFROLOGIA. Article. 38(6):606-615.
[doi:10.1016/j.nefro.2018.04.004]
Gonzalez-Blazquez, R, Somoza, B, Gil-Ortega, M, Martin Ramos M, Ramiro-Cortijo, D, Vega-Martin, E, Schulz, A, Ruilope, LM, Kolkhof, P, Kreutz, R, Fernandez-Alfonso, MS (2018).

Finerenone Attenuates Endothelial Dysfunction and Albuminuria in a Chronic Kidney Disease Model by a Reduction in Oxidative Stress

Frontiers in Pharmacology. Article. 9:1131-1131.
[doi:10.3389/fphar.2018.01131]
Banegas JR, Ruilope LM, Williams B (2018).

2018 ESC/ESH Guidelines for the management of arterial hypertension The Task Force for the management of arterial hypertension of the European Society of Cardiology and the European Society of Hypertension

JOURNAL OF HYPERTENSION. Article. 36(10):1953-2041.
[doi:10.1097/HJH.0000000000001940]
Banegas JR, Ruilope LM, Williams B (2018).

Ambulatory Blood Pressure and Mortality.

NEW ENGLAND JOURNAL OF MEDICINE. Letter. 379(13):1287-1288.
[doi:10.1056/NEJMc1809851]
Gaziano, JM, Brotons, C, Coppolecchia, R, Cricelli C, Darius, H, Gorelick, PB, Howard, G, Pearson, TA, Rothwell, PM, Ruilope, LM, Tendera, M, Tognoni, G, ARRIVE Executive Comm (2018).

Use of aspirin to reduce risk of initial vascular events in patients at moderate risk of cardiovascular disease (ARRIVE): a randomised, double-blind, placebo-controlled trial

LANCET. Article. 392(10152):1036-1046.
[doi:10.1016/S0140-6736(18)31924-X]
Drawz, PE, Brown, R, De Nicola L, Fujii, N, Gabbai, FB, Gassman, J, He, J, Iimuro, S, Lash, J, Minutolo, R, Phillips, RA, Rudser, K, Ruilope, L, Steigerwalt, S, Townsend, RR, Xie, DW, Rahman, M, CRIC Study Investigators (2018).

Variations in 24-Hour BP Profiles in Cohorts of Patients with Kidney Disease around the World The I-DARE Study

Clinical Journal of the American Society of Nephrology. Article. 13(9):1348-1357.
[doi:10.2215/CJN.13181117]
Williams, B, Mancia, G, Spiering, W, Rosei, EA, Azizi, M, Burnier, M, Clement, DL, Coca, A, de Simone, G, Dominiczak, A, Kahan, T, Mahfoud, F, Redon, J, Ruilope, L, Zanchetti, A, Kerins, M, Kjeldsen, SE, Kreutz, R, Laurent, S, Lip, GYH, McManus, R, Narkiewicz, K, Ruschitzka, F, Schmieder, RE, Shlyakhto, E, Tsioufis, C, Aboyans, V, Desormais, I, Task Force Management Arteria, European Soc Hypertension ESH (2018).

2018 ESC/ESH Guidelines for the management of arterial hypertension

EUROPEAN HEART JOURNAL. Review. 39(33):3021-3104.
[doi:10.1093/eurheartj/ehy339]
Banegas JR, Ruilope LM (2018).

The epidemiological magnitude of white-coat hypertension and masked hypertension in Africa

Journal of Clinical Hypertension. Editorial Material. 20(8):1173-1175.
[doi:10.1111/jch.13328]
Beaney T, Schutte AE, Tomaszewski M, Ariti C, Burrell LM, Castillo RR, Charchar FJ, Damasceno A, Kruger R, Lackland DT, Nilsson PM, Prabhakaran D, Ramirez AJ, Schlaich MP, Wang J, Weber MA, Poulter NR, MMM Investigators (2018).

May Measurement Month 2017: an analysis of blood pressure screening results worldwide

Lancet Global Health. Article. 6(7):736-743.
[doi:10.1016/S2214-109X(18)30259-6]
de la Sierra, A, Armario, P, Oliveras, A, Banegas, JR, Gorostidi, M, Vinyoles, E, de la Cruz, JJ, Segura, J, Ruilope, LM (2018).

Antihypertensive drug use in resistant and nonresistant hypertension and in controlled and uncontrolled resistant hypertension

JOURNAL OF HYPERTENSION. Article. 36(7):1563-1570.
[doi:10.1097/HJH.0000000000001729]
Val-Blasco, A, Navarro-García, JA, Tamayo, M, Piedras, MJ, Prieto, P, Delgado, C, Ruiz-Hurtado, G, Rozas-Romero, L, Gil-Fernández, M, Zaragoza, C, Boscá, L, Fernández-Velasco, M (2018).

Deficiency of NOD1 Improves the beta-Adrenergic Modulation of Ca2+ Handling in a Mouse Model of Heart Failure

Frontiers in Physiology. Article. 9:702-702.
[doi:10.3389/fphys.2018.00702]
de la Sierra A, Banegas JR, Vinyoles E, Segura J, Gorostidi M, de la Cruz JJ, Ruilope LM (2018).

Prevalence of Masked Hypertension in Untreated and Treated Patients With Office Blood Pressure Below 130/80 mm Hg

CIRCULATION. Letter. 137(24):2651-2653.
[doi:10.1161/CIRCULATIONAHA.118.034619]
Gijon-Conde, T, Graciani, A, Lopez-Garcia, E, Garcia-Esquinas, E, Laclaustra, M, Ruilope, LM, Rodriguez-Artalejo, F, Banegas, JR (2018).

Frailty, Disability, and Ambulatory Blood Pressure in Older Adults

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. Article. 19(5):433-438.
[doi:10.1016/j.jamda.2017.11.014]
Sarafidis, PA, Ruilope, LM, Loutradis, C, Gorostidi, M, de la Sierra, A, de la Cruz, JJ, Vinyoles, E, Divison-Garrote, JA, Segura, J, Banegas, JR (2018).

Blood pressure variability increases with advancing chronic kidney disease stage: a cross-sectional analysis of 16546 hypertensive patients

JOURNAL OF HYPERTENSION. Article. 36(5):1076-1085.
[doi:10.1097/HJH.0000000000001670]
Banegas JR, Ruilope LM, de la Sierra A, Vinyoles E, Gorostidi M, de la Cruz JJ, Ruiz-Hurtado G, Segura J, Rodríguez-Artalejo F, Williams B (2018).

Relationship between Clinic and Ambulatory Blood-Pressure Measurements and Mortality

NEW ENGLAND JOURNAL OF MEDICINE. Article. 378(16):1509-1520.
[doi:10.1056/NEJMoa1712231]
Baldan-Martin, M, Rodríguez-Sánchez, E, González-Calero, L, Ruilope, LM, Alvarez-Llamas, G, Barderas, MG, Ruiz-Hurtado, G (2018).

Translational science in albuminuria: a new view of de novo albuminuria under chronic RAS suppression

CLINICAL SCIENCE. Review. 132(7):739-758.
[doi:10.1042/CS20180097]
Santos-Lozano A, Baladron C, Martin-Hernandez J, Morales JS, Ruilope L, Lucia A (2018).

mHealth and the legacy of John Snow

LANCET. Letter. 391(10129):1479-1480.
[doi:10.1016/S0140-6736(18)30783-9]
Ruilope LM, Nunes Filho ACB, Nadruz W, Rodríguez Rosales FF, Verdejo-Paris J (2018).

Obesity and hypertension in Latin America: Current perspectives.

Hipertension y Riesgo Vascular. Article. 35(2):70-76.
[doi:10.1016/j.hipert.2017.12.004]
Navarro-García, JA, Fernández-Velasco, M, Delgado, C, Delgado, JF, Kuro-o, M, Ruilope, LM, Ruiz-Hurtado, G (2018).

PTH, vitamin D, and the FGF-23-klotho axis and heart: Going beyond the confines of nephrology

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. Review. 48(4).
[doi:10.1111/eci.12902]
Ruilope LM, Banegas JR (2018).

The use of antihypertensive fixed combinations in clinical practice needs a reappraisal

Journal of Clinical Hypertension. Editorial Material. 20(4):716-717.
[doi:10.1111/jch.13244]
Mesquita, TR, Auguste, G, Falcon, D, Ruiz-Hurtado, G, Salazar-Enciso, R, Sabourin, J, Lefebvre, F, Viengchareun, S, Kobeissy, H, Lechene, P, Nicolas, V, Fernandez-Celis, A, Gomez, S, Santos, SL, Morel, E, Rueda, A, Lopez-Andres, N, Gomez, AM, Lombes, M, Benitah, JP (2018).

Specific Activation of the Alternative Cardiac Promoter of Cacna1c by the Mineralocorticoid Receptor

CIRCULATION RESEARCH. Article. 122(7):49-61.
[doi:10.1161/CIRCRESAHA.117.312451]
Baldan-Martin, M, Lopez, JA, Corbacho-Alonso, N, Martinez, PJ, Rodriguez-Sanchez, E, Mourino-Alvarez, L, Sastre-Oliva, T, Martin-Rojas, T, Rincon, R, Calvo, E, Vazquez, J, Vivanco, F, Padial, LR, Alvarez-Llamas, G, Ruiz-Hurtado, G, Ruilope, LM, Barderas, MG (2018).

Potential role of new molecular plasma signatures on cardiovascular risk stratification in asymptomatic individuals

SCIENTIFIC REPORTS. Article. 8(1):4802-4802.
[doi:10.1038/s41598-018-23037-7]
Martin-Lorenzo M, Gonzalez-Calero L, Martinez PJ, Baldan-Martin M, Lopez JA, Ruiz-Hurtado G, de la Cuesta F, Segura J, Vazquez J, Vivanco F, Barderas MG, Ruilope LM, Alvarez-Llamas G (2018).

Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria (vol 7, 2017)

SCIENTIFIC REPORTS. Correction. 8(1):4154-4154.
[doi:10.1038/s41598-018-22185-0]
Rossi, GP, Seccia, TM, Barton, M, Danser AHJ, de Leeuw, PW, Dhaun, N, Rizzoni, D, Rossignol, P, Ruilope, LM, van den Meiracker, AH, Ito, S, Hasebe, N, Webb, DJ (2018).

Endothelial factors in the pathogenesis and treatment of chronic kidney disease Part II: Role in disease conditions: a joint consensus statement from the European Society of Hypertension Working Group on Endothelin and Endothelial Factors and the Japanese Society of Hypertension

JOURNAL OF HYPERTENSION. Article. 36(3):462-471.
[doi:10.1097/HJH.0000000000001600]
Rossi, GP, Seccia, TM, Barton, M, Danser AHJ, de Leeuw, PW, Dhaun, N, Rizzoni, D, Rossignol, P, Ruilope, LM, van den Meiracker, AH, Ito, S, Hasebe, N, Webb, DJ (2018).

Endothelial factors in the pathogenesis and treatment of chronic kidney disease Part I: General mechanisms: a joint consensus statement from the European Society of Hypertension Working Group on Endothelin and Endothelial Factors and The Japanese Society of Hypertension

JOURNAL OF HYPERTENSION. Article. 36(3):451-461.
[doi:10.1097/HJH.0000000000001599]
Ruiz-Hurtado, G, Delgado, C, Gomez, AM, Pereira, L (2018).

TNF-Alpha Mediates Gender Specific Ca2+ Signalling Dysfunction in Type 2 Diabetes

BIOPHYSICAL JOURNAL. Meeting Abstract. 114(3):618-618.
[doi:10.1016/j.bpj.2017.11.3344]
Banegas JR, Ruilope LM, Williams B (2018).

White-coat UnControlled Hypertension, Masked UnControlled Hypertension, and True UnControlled Hypertension, phonetic and mnemonic terms for treated hypertension phenotypes

JOURNAL OF HYPERTENSION. Letter. 36(2):446-447.
[doi:10.1097/HJH.0000000000001615]
Ruiz-Hurtado G, Ruilope LM (2018).

Microvascular injury and the kidney in hypertension.

Hipertension y Riesgo Vascular. Article. 35(1):24-29.
[doi:10.1016/j.hipert.2017.03.002]

2017

Rodriguez-Padial L, Akerström F, Barderas MG, Vivanco F, Arias MA, Segura J, Ruilope LM (2017).

Progression of Renal Insufficiency in Patients with Essential Hypertension Treated with Renin Angiotensin Aldosterone System Blockers: An Electrocardiographic Correlation.

Diseases. Article. 5(4).
[doi:10.3390/diseases5040033]
Armario P, Calhoun DA, Oliveras A, Blanch P, Vinyoles E, Banegas JR, Gorostidi M, Segura J, Ruilope LM, Dudenbostel T, de la Sierra A (2017).

Prevalence and Clinical Characteristics of Refractory Hypertension.

JOURNAL OF THE AMERICAN HEART ASSOCIATION. Article. 6(12).
[doi:10.1161/JAHA.117.007365]
Chatzikyrkou, C, Menne, J, Izzo, J, Viberti, G, Rabelink, T, Ruilope, LM, Rump, C, Mertens, PR, Haller, H (2017).

Predictors for the development of microalbuminuria and interaction with renal function.

JOURNAL OF HYPERTENSION. Article. 35(12):2501-2509.
[doi:10.1097/HJH.0000000000001491]
Karpetas, A, Loutradis, C, Bikos, A, Tzanis, G, Koutroumpas, G, Lazaridis, AA, Mavromatidis, K, Liakopoulos, V, Papagianni, A, Zebekakis, P, Ruilope, LM, Parati, G, Sarafidis, PA (2017).

Blood pressure variability is increasing from the first to the second day of the interdialytic interval in hemodialysis patients.

JOURNAL OF HYPERTENSION. Article. 35(12):2517-2526.
[doi:10.1097/HJH.0000000000001478]
de la Sierra A, Vinyoles E, Banegas JR, Segura J, Gorostidi M, de la Cruz JJ, Ruilope LM (2017).

Prevalence and clinical characteristics of white-coat hypertension based on different definition criteria in untreated and treated patients.

JOURNAL OF HYPERTENSION. Article. 35(12):2388-2394.
[doi:10.1097/HJH.0000000000001493]
Ruiz-Hurtado G, Ruilope LM (2017).

Advantages of sacubitril/valsartan beyond blood pressure control in arterial hypertension.

EUROPEAN HEART JOURNAL. Editorial Material. 38(44):3318-3320.
[doi:10.1093/eurheartj/ehx560]
Mahfoud F, Schmieder RE, Azizi M, Pathak A, Sievert H, Tsioufis C, Zeller T, Bertog S, Blankestijn PJ, Böhm M, Burnier M, Chatellier G, Durand Zaleski I, Ewen S, Grassi G, Joner M, Kjeldsen SE, Lobo MD, Lotan C, Felix Lüscher T, Parati G, Rossignol P, Ruilope L, Sharif F, van Leeuwen E, Volpe M, Windecker S, Witkowski A, Wijns W (2017).

Proceedings from the 2nd European Clinical Consensus Conference for device-based therapies for hypertension: state of the art and considerations for the future.

EUROPEAN HEART JOURNAL. Article. 38(44):3272-3281.
[doi:10.1093/eurheartj/ehx215]
Martin-Lorenzo M, Martinez PJ, Baldan-Martin M, Ruiz-Hurtado G, Prado JC, Segura J, de la Cuesta F, Barderas MG, Vivanco F, Ruilope LM, Alvarez-Llamas G (2017).

Citric Acid Metabolism in Resistant Hypertension: Underlying Mechanisms and Metabolic Prediction of Treatment Response.

HYPERTENSION. Article. 70(5):1049-1056.
[doi:10.1161/HYPERTENSIONAHA.117.09819]
Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, de Leeuw PW, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, Williams B (2017).

Reply.

JOURNAL OF HYPERTENSION. Letter. 35(11):2327-2328.
[doi:10.1097/HJH.0000000000001526]
Calvo-Bonacho E, Catalina-Romero C, Cabrera M, Fernández-Labandera C, Sánchez Chaparro MÁ, Brotons C, Ruilope LM (2017).

Association Between Improvement in Cardiovascular Risk Profile and; Changes in Sickness Absence: Results of the ICARIA Study

REVISTA ESPANOLA DE CARDIOLOGIA. Article. 70(11):941-951.
[doi:10.1016/j.recesp.2017.02.004]
Ruiz-Hurtado G, Banegas JR, Sarafidis PA, Volpe M, Williams B, Ruilope LM (2017).

Has the SPRINT trial introduced a new blood-pressure goal in hypertension?

NATURE REVIEWS CARDIOLOGY. Article. 14(9):560-566.
[doi:10.1038/nrcardio.2017.74]
Martin-Lorenzo, M, Gonzalez-Calero, L, Martinez, PJ, Baldan-Martin, M, Lopez, JA, Ruiz-Hurtado, G, de la Cuesta, F, Segura, J, Vazquez, J, Vivanco, F, Barderas, MG, Ruilope, LM, Alvarez-Llamas, G (2017).

Immune system deregulation in hypertensive patients chronically RAS suppressed developing albuminuria.

SCIENTIFIC REPORTS. Article. 7(1):8894-8894.
[doi:10.1038/s41598-017-09042-2]
Santos-Lozano A, Lucia A, Ruilope L, Pitsiladis YP (2017).

Born to run: our future depends on it.

LANCET. Editorial Material. 390(10095):635-636.
[doi:10.1016/S0140-6736(17)32103-7]
Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, Williams B, de Leeuw PW (2017).

Expertise: no longer a sine qua non for guideline authors?

JOURNAL OF HYPERTENSION. Editorial Material. 35(8):1564-1566.
[doi:10.1097/HJH.0000000000001435]
Boccara F, Dent R, Ruilope L, Valensi P (2017).

Practical Considerations for the Use of Subcutaneous Treatment in the Management of Dyslipidaemia.

ADVANCES IN THERAPY. Review. 34(8):1876-1896.
[doi:10.1007/s12325-017-0586-8]
Messerli FH, Hofstetter L, Agabiti-Rosei E, Burnier M, Elliott WJ, Franklin SS, Grodzicki T, Kario K, Kjeldsen SE, Kostis JB, Laurent S, Leenen FH, Lund-Johansen P, Mancia G, Narkiewicz K, Papademetriou V, Parati G, Poulter N, Redon J, Rimoldi SF, Ruilope LM, Schiffrin EL, Schmieder RE, Schwartz AB, Sever P, Sowers JR, Staessen JA, Wang J, Weber M, Williams B (2017).

No Longer a Sine Qua Non for Guideline Authors?

HYPERTENSION. Editorial Material. 70(2):235-237.
[doi:10.1161/HYPERTENSIONAHA.117.09470]
Martinez PJ, Baldan-Martin M, Martin-Lorenzo M, Lopez JA, Vazquez J, Calvo E, Cabrera M, Ruiz-Hurtado G, Ruilope LM, Vivanco F, Barderas MG, Alvarez-Llamas G (2017).

CARDIOVASCULAR RISK IN YOUNG POPULATION: IDENTIFICATION OF PROTEIN; SIGNATURES IN URINE

ATHEROSCLEROSIS. Meeting Abstract. 263:106-106.
[doi:10.1016/j.atherosclerosis.2017.06.342]
Baldan Martin M, Lopez JA, Mourino-Alvarez L, Sastre-Oliva T, Martin-Rojas T, Corbacho N, Martinez PJ, Vazquez J, Calvo E, Vivanco F, Alvarez-Llamas G, Ruiz-Hurtado G, Padial LR, Ruilope LM, Barderas MG (2017).

PLASMA PROTEOMIC PROFILING TO STRATIFY CARDIOVASCULAR RISK IN YOUNG; POPULATION

ATHEROSCLEROSIS. Meeting Abstract. 263:192-192.
[doi:10.1016/j.atherosclerosis.2017.06.615]
Pulido-Olmo H, Rodríguez-Sánchez E, Navarro-García JA, Barderas MG, Álvarez-Llamas G, Segura J, Fernández-Alfonso M, Ruilope LM, Ruiz-Hurtado G (2017).

Rapid, Automated, and Specific Immunoassay to Directly Measure Matrix Metalloproteinase-9-Tissue Inhibitor of Metalloproteinase-1 Interactions in Human Plasma Using AlphaLISA Technology: A New Alternative to Classical ELISA.

Frontiers in Immunology. Article. 8:853-853.
[doi:10.3389/fimmu.2017.00853]
Gonzalez-Calero L, Martínez PJ, Martin-Lorenzo M, Baldan-Martin M, Ruiz-Hurtado G, la Cuesta F, Calvo E, Segura J, Lopez JA, Vázquez J, Barderas MG, Ruilope LM, Vivanco F, Alvarez-Llamas G (2017).

Urinary exosomes reveal protein signatures in hypertensive patients with albuminuria.

Oncotarget. Article. 8(27):44217-44231.
[doi:10.18632/oncotarget.17787]
Sarafidis PA, Alexandrou ME, Ruilope LM (2017).

A review of chemical therapies for treating diabetic hypertension.

EXPERT OPINION ON PHARMACOTHERAPY. Review. 18(9):909-923.
[doi:10.1080/14656566.2017.1328054]
Sarafidis PA, Lazaridis AA, Ruiz-Hurtado G, Ruilope LM (2017).

Blood pressure reduction in diabetes: lessons from ACCORD, SPRINT and; EMPA-REG OUTCOME

NATURE REVIEWS ENDOCRINOLOGY. Review. 13(6):365-374.
[doi:10.1038/nrendo.2016.209]
Marquez DF, Ruiz-Hurtado G, Ruilope L (2017).

The impact of antihypertensives on kidney disease.

F1000research. Article. 6:611-611.
[doi:10.12688/f1000research.9916.1]
Ruiz-Hurtado G, Ruilope LM (2017).

Sacubitril/valsartan in the treatment of arterial hypertension: an; unaccomplished promise?

HYPERTENSION RESEARCH. Editorial Material. 40(5):439-440.
[doi:10.1038/hr.2017.27]
Divisón-Garrote JA, Ruilope LM, de la Sierra A, de la Cruz JJ, Vinyoles E, Gorostidi M, Escobar-Cervantes C, Velilla-Zancada SM, Segura J, Banegas JR (2017).

Magnitude of Hypotension Based on Office and Ambulatory Blood Pressure; Monitoring: Results From a Cohort of 5066 Treated Hypertensive Patients; Aged 80 Years and Older

JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION. Article. 18(5).
[doi:10.1016/j.jamda.2017.01.015]
Vinyoles E, de la Sierra A, Roso-Llorach A, Banegas JR, de la Cruz JJ, Gorostidi M, Segura J, Divisón JA, Ruíz-Hurtado G, Ruilope LM, Spanish ABPM Registry Investigators (2017).

24-h pulse pressure cutoff point definition by office pulse pressure in; a population of Spanish older hypertensive patients

JOURNAL OF HYPERTENSION. Article. 35(5):1011-1018.
[doi:10.1097/HJH.0000000000001268]
Ruilope LM, Tamargo J (2017).

Aldosterone a Relevant Factor in the Beginning and Evolution of Arterial; Hypertension

AMERICAN JOURNAL OF HYPERTENSION. Review. 30(5):468-469.
[doi:10.1093/ajh/hpx010]
Tamargo J, Rosano GM, Delpón E, Ruilope L, López-Sendón J (2017).

Pharmacological reasons that may explain why randomized clinical trials; have failed in acute heart failure syndromes

International Journal of Cardiology. Review. 233:1-11.
[doi:10.1016/j.ijcard.2016.11.124]
Sarafidis PA, Persu A, Agarwal R, Burnier M, de Leeuw P, Ferro CJ, Halimi JM, Heine GH, Jadoul M, Jarraya F, Kanbay M, Mallamaci F, Mark PB, Ortiz A, Parati G, Pontremoli R, Rossignol P, Ruilope L, Van der Niepen P, Vanholder R, Verhaar MC, Wiecek A, Wuerzner G, London GM, Zoccali C (2017).

Hypertension in dialysis patients: a consensus document by the European Renal and Cardiovascular Medicine (EURECA-m) working group of the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) and the Hypertension and the Kidney working group of the European Society of Hypertension (ESH).

NEPHROLOGY DIALYSIS TRANSPLANTATION. Review. 32(4):620-640.
[doi:10.1093/ndt/gfw433]
Sarafidis PA, Persu A, Agarwal R, Burnier M, de Leeuw P, Ferro C, Halimi JM, Heine G, Jadoul M, Jarraya F, Kanbay M, Mallamaci F, Mark PB, Ortiz A, Parati G, Pontremoli R, Rossignol P, Ruilope L, Van der Niepen P, Vanholder R, Verharr MC, Wiecek A, Wuerzner G, London GM, Zoccali C (2017).

Hypertension in dialysis patients: a consensus document by the European; Renal and Cardiovascular Medicine (EURECA-m) working group of the; European Renal Association European Dialysis and Transplant Association; (ERA-EDTA) and the Hypertension and the Kidney working group of the; European Society of Hypertension (ESH)

JOURNAL OF HYPERTENSION. Article. 35(4):657-676.
[doi:10.1097/HJH.0000000000001283]
Ruilope LM, Tamargo J (2017).

Renin-angiotensin system blockade: Finerenone

NEPHROLOGIE & THERAPEUTIQUE. Article. 13:47-53.
[doi:10.1016/j.nephro.2017.02.003]
de la Cuesta F, Baldan-Martin M, Moreno-Luna R, Alvarez-Llamas G, Gonzalez-Calero L, Mourino-Alvarez L, Sastre-Oliva T, López JA, Vázquez J, Ruiz-Hurtado G, Segura J, Vivanco F, Ruilope LM, Barderas MG (2017).

Kalirin and CHD7: novel endothelial dysfunction indicators in; circulating extracellular vesicles from hypertensive patients with; albuminuria

Oncotarget. Article. 8(9):15553-15562.
[doi:10.18632/oncotarget.14948]
Banegas JR, Ruilope LM, de la Sierra A, Vinyoles E, Gorostidi M, de la Cruz JJ, Segura J, Oliveras A, Martell N, García-Puig J, Williams B (2017).

Clinic Versus Daytime Ambulatory Blood Pressure Difference in; Hypertensive Patients The Impact of Age and Clinic Blood Pressure

HYPERTENSION. Article. 69(2):211-219.
[doi:10.1161/HYPERTENSIONAHA.116.08567]
Ruiz-Hurtado G, García-Prieto CF, Pulido-Olmo H, Velasco-Martín JP, Villa-Valverde P, Fernández-Valle ME, Boscá L, Fernández-Velasco M, Regadera J, Somoza B, Fernández-Alfonso MS (2017).

Mild and Short-Term Caloric Restriction Prevents Obesity-Induced; Cardiomyopathy in Young Zucker Rats without Changing in Metabolites and; Fatty Acids Cardiac Profile

Frontiers in Physiology. Article. 8:42-42.
[doi:10.3389/fphys.2017.00042]
Val-Blasco A, Piedras MJ, Ruiz-Hurtado G, Suarez N, Prieto P, Gonzalez-Ramos S, Gómez-Hurtado N, Delgado C, Pereira L, Benito G, Zaragoza C, Domenech N, Crespo-Leiro MG, Vasquez-Echeverri D, Nuñez G, Lopez-Collazo E, Boscá L, Fernández-Velasco M (2017).

Role of NOD1 in Heart Failure Progression via Regulation of Ca2+; Handling

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Article. 69(4):423-433.
[doi:10.1016/j.jacc.2016.10.073]
Linz D, Mancia G, Mahfoud F, Narkiewicz K, Ruilope L, Schlaich M, Kindermann I, Schmieder RE, Ewen S, Williams B, Böhm M, Global SYMPLICITY Registry Investigators (2017).

Renal artery denervation for treatment of patients with self-reported; obstructive sleep apnea and resistant hypertension: results fromthe; Global SYMPLICITY Registry

JOURNAL OF HYPERTENSION. Article. 35(1):148-153.
[doi:10.1097/HJH.0000000000001142]
Ruilope LM, Chagas AC, Brandão AA, Gómez-Berroterán R, Alcalá JJ, Paris JV, Cerda JJ (2017).

Hypertension in Latin America: Current perspectives on trends and characteristics.

Hipertension y Riesgo Vascular. Article. 34(1):50-56.
[doi:10.1016/j.hipert.2016.11.005]
Baldan-Martin M, de la Cuesta F, Alvarez-Llamas G, Ruiz-Hurtado G, Ruilope LM, Barderas MG (2017).

Proteomic Analysis of Blood Extracellular Vesicles in Cardiovascular Disease by LC-MS/MS Analysis

Methods in molecular biology (Clifton, N.J.). Article. 1619:141-149.
[doi:10.1007/978-1-4939-7057-5_11]

2016

Böhm M, Ukena C, Ewen S, Linz D, Zivanovic I, Hoppe U, Narkiewicz K, Ruilope L, Schlaich M, Negoita M, Schmieder R, Williams B, Zeymer U, Zirlik A, Mancia G, Mahfoud F, Global SYMPLICITY Registry Investigators (2016).

Renal denervation reduces office and ambulatory heart rate in patients with uncontrolled hypertension: 12-month outcomes from the global SYMPLICITY registry

JOURNAL OF HYPERTENSION. Article. 34(12):2480-2486.
[doi:10.1097/HJH.0000000000001085]
Gonzalez-Calero, L, Martin-Lorenzo, M, Martinez, PJ, Baldan-Martin, M, Ruiz-Hurtado, G, Segura, J, De La Cuesta, F, Barderas, MG, Ruilope, LM, Vivanco, F, Alvarez-Llamas, G (2016).

Hypertensive patients exhibit an altered metabolism. A specific metabolite signature in urine is able to predict albuminuria progression

TRANSLATIONAL RESEARCH. Article. 178:25-37.
[doi:10.1016/j.trsl.2016.07.003]
Abellan Aleman, Jose, Zafrilla Rentero, Maria Pilar, Montoro-Garcia, Silvia, Mulero, Juana, Perez Garrido, Alfonso, Leal, Mariano, Guerrero, Lucia, Ramos, Elena, Miguel Ruilope, Luis (2016).

Adherence to the ``Mediterranean Diet'' in Spain and Its Relationship with Cardiovascular Risk (DIMERICA Study)

Nutrients. Article. 8(11).
[doi:10.3390/nu8110680]
Bohm, M, Brilakis, N, Mancia, G, Narkiewicz, K, Ruilope, L, Schlaich, M, Mahfoud, F (2016).

Renal denervation treatment with the Symplicity Spyral multielectrode; catheter: 6-month safety and blood pressure outcomes from the Global; SYMPLICITY Registry

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Meeting Abstract. 68(18):308-308.
Mahfoud, F, Brilakis, N, Bohm, M, Narkiewicz, K, Ruilope, L, Schlaich, M, Mancia, G (2016).

Long-term (3-year) safety and effectiveness from the Global SYMPLICITY; Registry of renal denervation in a real world patient population with; uncontrolled hypertension

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Meeting Abstract. 68(18):308-308.
[doi:10.1016/j.jacc.2016.09.791]
Ruiz-Hurtado G, Vigil L, Ruilope LM (2016).

La mejoría del pronóstico cardiovascular de la diabetes mellitus tipo 2 ¿es una realidad?

Hipertension y Riesgo Vascular. Article. 33(4):123-125.
[doi:10.1016/j.hipert.2016.10.001]
Ruiz-Hurtado G, Ruilope LM, de la Sierra A, Sarafidis P, de la Cruz JJ, Gorostidi M, Segura J, Vinyoles E, Banegas JR (2016).

Association Between High and Very High Albuminuria and Nighttime Blood Pressure: Influence of Diabetes and Chronic Kidney Disease

DIABETES CARE. Article. 39(10):1729-1737.
[doi:10.2337/dc16-0748]
Prado JC, Ruilope LM, Segura J (2016).

Utilidad de la espironolactona en el manejo farmacológico de la hipertensión arterial resistente. Comentarios sobre el estudio Pathway-2.

Hipertension y Riesgo Vascular. Article. 33(4):150-154.
[doi:10.1016/j.hipert.2016.05.003]
Prado JC, Salado D, Ruilope LM, Segura J (2016).

Second denervation in a patient with resistant hypertension

Clinical Research in Cardiology. Letter. 105(10):880-883.
[doi:10.1007/s00392-016-0997-6]
Ruiz-Hurtado G, Sarafidis P, Fernández-Alfonso MS, Waeber B, Ruilope LM (2016).

Global cardiovascular protection in chronic kidney disease

NATURE REVIEWS CARDIOLOGY. Review. 13(10):603-608.
[doi:10.1038/nrcardio.2016.48]
Divisón-Garrote JA, Banegas JR, De la Cruz JJ, Escobar-Cervantes C, De la Sierra A, Gorostidi M, Vinyoles E, Abellán-Aleman J, Segura J, Ruilope LM (2016).

Hypotension based on office and ambulatory monitoring blood pressure. Prevalence and clinical profile among a cohort of 70,997 treated hypertensives

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION. Article. 10(9):714-723.
[doi:10.1016/j.jash.2016.06.035]
Calvo-bonacho, E, Catalina-romero, C, Sainz-gutierrez, JC, Cabrera-sierra, M, Quevedo-aguado, L, Fernandez-labandera, C, Brotons, C, Ruilope, LM (2016).

[OP.LB01.06] EFFECTIVENESS OF A COMPREHENSIVE HEALTH PROMOTION STRATEGY IN WORKERS WITH HIGH CARDIOVASCULAR RISK.

JOURNAL OF HYPERTENSION. Article. 34 Suppl 2:37-37.
[doi:10.1097/01.hjh.0000491430.39058.d7]
de la Sierra A, Vinyoles E, Banegas JR, Parati G, de la Cruz JJ, Gorostidi M, Segura J, Ruilope LM (2016).

Short-Term and Long-Term Reproducibility of Hypertension Phenotypes Obtained by Office and Ambulatory Blood Pressure Measurements

Journal of Clinical Hypertension. Article. 18(9):927-933.
[doi:10.1111/jch.12792]
van Veldhuisen DJ, Ruilope LM, Maisel AS, Damman K (2016).

Biomarkers of renal injury and function: diagnostic, prognostic and therapeutic implications in heart failure

EUROPEAN HEART JOURNAL. Review. 37(33):2577-13.
[doi:10.1093/eurheartj/ehv588]
Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, Falk V, González-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GM, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P, Authors/Task Force Members, Document Reviewers (2016).

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure: The Task Force for the diagnosis and treatment of acute and chronic heart failure of the European Society of Cardiology (ESC). Developed with the special contribution of the Heart Failure Association (HFA) of the ESC

EUROPEAN JOURNAL OF HEART FAILURE. Article. 18(8):891-975.
[doi:10.1002/ejhf.592]
Zannad F, Rossignol P, Stough WG, Epstein M, Alonso Garcia Mde L, Bakris GL, Butler J, Kosiborod M, Berman L, Mebazaa A, Rasmussen HS, Ruilope LM, Stockbridge N, Thompson A, Wittes J, Pitt B (2016).

New approaches to hyperkalemia in patients with indications for renin angiotensin aldosterone inhibitors: Considerations for trial design and regulatory approval

International Journal of Cardiology. Review. 216:46-51.
[doi:10.1016/j.ijcard.2016.04.127]
Cremer A, Amraoui F, Lip GY, Morales E, Rubin S, Segura J, Van den Born BJ, Gosse P (2016).

From malignant hypertension to hypertension-MOD: a modern definition for an old but still dangerous emergency

JOURNAL OF HUMAN HYPERTENSION. Review. 30(8):463-466.
[doi:10.1038/jhh.2015.112]
Ponikowski P, Voors AA, Anker SD, Bueno H, Cleland JG, Coats AJ, Falk V, González-Juanatey JR, Harjola VP, Jankowska EA, Jessup M, Linde C, Nihoyannopoulos P, Parissis JT, Pieske B, Riley JP, Rosano GM, Ruilope LM, Ruschitzka F, Rutten FH, van der Meer P (2016).

2016 ESC Guidelines for the diagnosis and treatment of acute and chronic heart failure

EUROPEAN HEART JOURNAL. Review. 37(27, SI):2129-130.
[doi:10.1093/eurheartj/ehw128]
Baldan-Martin, M, Mourino-Alvarez, L, Gonzalez-Calero, L, Moreno-Luna, R, Sastre-Oliva, T, Ruiz-Hurtado, G, Segura, J, Lopez, JA, Vazquez, J, Vivanco, F, Alvarez-Llamas, G, Ruilope, LM, Cuesta F, Barderas, MG (2016).

Plasma Molecular Signatures in Hypertensive Patients With Renin-Angiotensin System Suppression New Predictors of Renal Damage and De Novo Albuminuria Indicators

HYPERTENSION. Article. 68(1):157-157.
[doi:10.1161/HYPERTENSIONAHA.116.07412]
Ruilope LM, Nowack C, Bakris GL (2016).

Masked and Nocturnal Hypertension in the ARTS-DN ABPM Sub-Study with Finerenone.

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION. Article. 10 Suppl 1.
[doi:10.1016/j.jash.2016.06.021]
Martin, M. Baldan, Mourino-Alvarez, L., Gonzalez-Calero, L., Sastre-Oliva, T., Lopez, J. A., Vazquez, J., Alvarez-Llamas, G., Luis, M. Ruilope, De la Cuesta, F., Barderas, M. G. (2016).

Plasma proteomics in hypertension: prediction and follow-up of albuminuria during chronic renin-angiotensin system suppression

CARDIOVASCULAR RESEARCH. Meeting Abstract. 111(1):115-116.
Ruilope, LM, SEVITENSION Study Investigators (2016).

Fixed-Combination Olmesartan/Amlodipine Was Superior to Perindopril plus Amlodipine in Reducing Central Systolic Blood Pressure in Hypertensive Patients With Diabetes

Journal of Clinical Hypertension. Article. 18(6):528-535.
[doi:10.1111/jch.12673]
Pulido-Olmo, Helena, Garcia-Prieto, Concha F., Alvarez-Llamas, Gloria, Barderas, Maria G., Vivanco, Fernando, Aranguez, Isabel, Somoza, Beatriz, Segura, Julian, Kreutz, Reinhold, Fernandez-Alfonso, Maria S., Ruilope, Luis M., Ruiz-Hurtado, Gema (2016).

Role of matrix metalloproteinase-9 in chronic kidney disease: a new biomarker of resistant albuminuria

CLINICAL SCIENCE. Article. 130(7):525-538.
[doi:10.1042/CD20150517]
Diez, Javier, Ruilope, Luis M. (2016).

Serelaxin for the treatment of acute heart failure: a review with a focus on end-organ protection

European Heart Journal-Cardiovascular Pharmacotherapy. Review. 2(2):119-130.
[doi:10.1093/ehjcvp/pvv046]
Ruilope LM, Banegas JR (2016).

El estudio SPRINT en la práctica clínica: ¿se debe modificar el objetivo de control de la presión arterial?

Hipertension y Riesgo Vascular. Editorial Material. 33(2):47-50.
[doi:10.1016/j.hipert.2016.02.003]
Escobar C, Abad-Cardiel M, Prieto MA, de la Figuera M, Barrios V, Segura J (2016).

Cambios en los objetivos terapéuticos y grado de control de la hipertensión arterial: nuevas evidencias.

Hipertension y Riesgo Vascular. Article. 33(2):63-68.
[doi:10.1016/j.hipert.2016.01.002]
Schmieder RE, Bramlage P, Haller H, Ruilope LM, Böhm M, ROADMAP Investigators (2016).

The Effect of Resting Heart Rate on the New Onset of Microalbuminuria in Patients With Type 2 Diabetes A Subanalysis of the ROADMAP Study

MEDICINE. Article. 95(15).
[doi:10.1097/MD.0000000000003122]
Brotons, C, Calvo-Bonacho, E, Moral, I, Puig, M, Garcia-Margallo, MT, Cortes-Arcas, MV, Catalina-Romero, C, Quevedo-Aguado, L, Ruilope, LM (2016).

Comparison of application of different methods to estimate lifetime cardiovascular risk

European Journal of Preventive Cardiology. Article. 23(6):564-571.
[doi:10.1177/2047487315579616]
Oliveras A, Segura J, Suarez C, García-Ortiz L, Abad-Cardiel M, Vigil L, Gómez-Marcos MA, Sans Atxer L, Martell-Claros N, Ruilope LM, de la Sierra A (2016).

Modification over time of pulse wave velocity parallel to changes in aortic BP, as well as in 24-h ambulatory brachial BP

JOURNAL OF HUMAN HYPERTENSION. Article. 30(3):186-190.
[doi:10.1038/jhh.2015.62]
Zanchetti, Alberto, Liu, Lisheng, Mancia, Giuseppe, Parati, Gianfranco, Grassi, Guido, Stramba-Badiale, Marco, Silani, Vincenzo, Bilo, Grzegorz, Corrao, Giovanni, Zambon, Antonella, Scotti, Lorenza, Zhang, Xinhua, Guan, Ting Rui, Zhang, Yuqing, Zhang, Xuezhong, Berge, Eivind, Redon, Josep, Narkiewicz, Krzysztof, Dominiczak, Anna, Nilsson, Peter, Viigimaa, Margus, Laurent, Stephane, Agabiti-Rosei, Enrico, Wu, Zhaosu, Zhu, Dingliang, Luis Rodicio, Jose, Miguel Ruilope, Luis, Martell-Claros, Nieves, Pinto, Fernando, Schmieder, Roland E., Burnier, Michel, Banach, Maciej, Cifkova, Renata, Farsang, Csaba, Konradi, Alexandra, Lazareva, Irina, Sirenko, Yuriy, Dorobantu, Maria, Postadzhiyan, Arman, Accetto, Rok, Jelakovic, Bojan, Lovic, Dragan, Manolis, Athanasios J., Stylianou, Philippos, Dicker, Dror, Wei, Gangzhi, Xu, Chengbin, Xie, Hengge, Coca, Antonio, O'Brien, John, Ford, Gary, ESH-CHL-SHOT Trial Investigators (2016).

Continuation of the ESH-CHL-SHOT trial after publication of the SPRINT: rationale for further study on blood pressure targets of antihypertensive treatment after stroke

JOURNAL OF HYPERTENSION. Editorial Material. 34(3):393-396.
[doi:10.1097/HJH.0000000000000853]
Ruiz-Hurtado G, Ruilope LM (2016).

New Strategy to Control Blood Pressure: Interactive Mobile Phone Support

Journal of Clinical Hypertension. Editorial Material. 18(2):109-110.
[doi:10.1111/jch.12683]
Gonzalez-Calero L, Martin-Lorenzo M, de la Cuesta F, Maroto AS, Baldan-Martin M, Ruiz-Hurtado G, Pulido-Olmo H, Segura J, Barderas MG, Ruilope LM, Vivanco F, Alvarez-Llamas G (2016).

Urinary alpha-1 antitrypsin and CD59 glycoprotein predict albuminuria development in hypertensive patients under chronic renin-angiotensin system suppression

Cardiovascular Diabetology. Article. 15(1):8-8.
[doi:10.1186/s12933-016-0331-7]
de la Cuesta F, Baldan-Martin M, Mourino-Alvarez L, Sastre-Oliva T, Alvarez-Llamas G, Gonzalez-Calero L, Ruiz-Hurtado G, Segura J, Vivanco F, Ruilope LM, Barderas MG (2016).

Estudio del riesgo cardiovascular en pacientes con bloqueo del sistema renina-angiotensina a través del proteoma de las vesículas extracelulares circulantes.

Hipertension y Riesgo Vascular. Abstract of Published Item. 33(1):21-27.
[doi:10.1016/j.hipert.2015.07.003]
de la Sierra A, Banegas JR, Vinyoles E, Gorostidi M, Segura J, de la Cruz JJ, Ruilope LM (2016).

Office and ambulatory blood pressure control in hypertensive patients treated with different two-drug and three-drug combinations

CLINICAL AND EXPERIMENTAL HYPERTENSION. Article. 38(4):409-414.
[doi:10.3109/10641963.2016.1148160]
Gorostidi M, Banegas JR, de la Sierra A, Vinyoles E, Segura J, Ruilope LM (2016).

Ambulatory blood pressure monitoring in daily clinical practice - the Spanish ABPM Registry experience

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. Review. 46(1):92-98.
[doi:10.1111/eci.12565]

2015

Rodríguez-Rodríguez P, de Pablo AL, Condezo-Hoyos L, Martín-Cabrejas MA, Aguilera Y, Ruiz-Hurtado G, Gutierrez-Arzapalo PY, Ramiro-Cortijo D, Fernández-Alfonso MS, González Mdel C, Arribas SM (2015).

Fetal undernutrition is associated with perinatal sex-dependent alterations in oxidative status

JOURNAL OF NUTRITIONAL BIOCHEMISTRY. Article. 26(12):1650-1659.
[doi:10.1016/j.jnutbio.2015.08.004]
Peña JC, Ruilope LM (2015).

LCZ696, The Need for an Indication in Arterial Hypertension

AMERICAN JOURNAL OF HYPERTENSION. Editorial Material. 28(12):1403-1404.
[doi:10.1093/ajh/hpv133]
Ruiz-Hurtado G, Ruilope LM (2015).

Salutary cardiovascular effects of antidiabetic drugs: myth or fact?

JOURNAL OF HYPERTENSION. Editorial Material. 33(11):2198-2199.
[doi:10.1097/HJH.0000000000000741]
de la Sierra, Alejandro, Gorostidi, Manuel, Banegas, Jose R., Segura, Julian, Vinyoles, Ernest, de la Cruz, Juan J., Ruilope, Luis M. (2015).

Ambulatory Blood Pressures in Hypertensive Patients Treated With One Antihypertensive Agent: Differences Among Drug Classes and Among Drugs Belonging to the Same Class

Journal of Clinical Hypertension. Article. 17(11):857-865.
[doi:10.1111/jch.12623]
Ruiz-Hurtado G, Gorostidi M, Waeber B, Ruilope LM (2015).

Ambulatory and home blood pressure monitoring in people with chronic kidney disease. Time to abandon clinic blood pressure measurements?

CURRENT OPINION IN NEPHROLOGY AND HYPERTENSION. Review. 24(6):488-491.
[doi:10.1097/MNH.0000000000000162]
Márquez DF, Ruiz-Hurtado G, Ruilope LM, Segura J (2015).

An update of the blockade of the renin angiotensin aldosterone system in clinical practice

EXPERT OPINION ON PHARMACOTHERAPY. Review. 16(15):2283-2292.
[doi:10.1517/14656566.2015.1079623]
Ruiz-Hurtado, Gema, Li, Linwei, Fernandez-Velasco, Maria, Rueda, Angelica, Lefebvre, Florence, Wang, Yueyi, Mateo, Philippe, Cassan, Cecile, Gellen, Barnabas, Benitah, Jean Pierre, Gomez, Ana Maria (2015).

Reconciling depressed Ca2+ sparks occurrence with enhanced RyR2 activity in failing mice cardiomyocytes

JOURNAL OF GENERAL PHYSIOLOGY. Article. 146(4):295-306.
[doi:10.1085/jgp.201511366]
Domínguez-Rodríguez A, Ruiz-Hurtado G, Sabourin J, Gómez AM, Alvarez JL, Benitah JP (2015).

Proarrhythmic effect of sustained EPAC activation on TRPC3/4 in rat ventricular cardiomyocytes

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. Article. 87:74-78.
[doi:10.1016/j.yjmcc.2015.07.002]
Martin-Lorenzo, Marta, Zubiri, Irene, Maroto, Aroa S., Gonzalez-Calero, Laura, Posada-Ayala, Maria, de la Cuesta, Fernando, Mourino-Alvarez, Laura, Lopez-Almodovar, Luis F., Calvo-Bonacho, Eva, Ruilope, Luis M., Padial, Luis R., Barderas, Maria G., Vivanco, Fernando, Alvarez-Llamas, Gloria (2015).

KLK1 and ZG16B proteins and arginine-proline metabolism identified as novel targets to monitor atherosclerosis, acute coronary syndrome and recovery

Metabolomics. Article. 11(5):1056-1067.
[doi:10.1007/s11306-014-0761-8]
Baldan-Martin, Montserrat, de la Cuesta, Fernando, Alvarez-Llamas, Gloria, Gonzalez-Calero, Laura, Ruiz-Hurtado, Gema, Moreno-Luna, Rafael, Mourino-Alvarez, Laura, Sastre-Oliva, Tamara, Segura, Julian, Padial, Luis R., Vivanco, Fernando, Ruilope, Luis M., Barderas, Maria G. (2015).

Prediction of development and maintenance of high albuminuria during chronic renin-angiotensin suppression by plasma proteomics

International Journal of Cardiology. Article. 196:170-177.
[doi:10.1016/j.ijcard.2015.05.148]
Hoshide S, Kario K, de la Sierra A, Bilo G, Schillaci G, Banegas JR, Gorostidi M, Segura J, Lombardi C, Omboni S, Ruilope L, Mancia G, Parati G (2015).

Ethnic Differences in the Degree of Morning Blood Pressure Surge and in Its Determinants Between Japanese and European Hypertensive Subjects Data From the ARTEMIS Study

HYPERTENSION. Article. 66(4):750-756.
[doi:10.1161/HYPERTENSIONAHA.115.05958]
Lazaridis, Antonios A., Sarafidis, Pantelis A., Ruilope, Luis M. (2015).

Ambulatory Blood Pressure Monitoring in the Diagnosis, Prognosis, and Management of Resistant Hypertension: Still a Matter of our Resistance?

CURRENT HYPERTENSION REPORTS. Review. 17(10):78-78.
[doi:10.1007/s11906-015-0590-9]
Bakris, George L., Agarwal, Rajiv, Chan, Juliana C., Cooper, Mark E., Gansevoort, Ron T., Haller, Hermann, Remuzzi, Giuseppe, Rossing, Peter, Schmieder, Roland E., Nowack, Christina, Kolkhof, Peter, Joseph, Amer, Pieper, Alexander, Kimmeskamp-Kirschbaum, Nina, Ruilope, Luis M., Mineralocorticoid Receptor (2015).

Effect of Finerenone on Albuminuria in Patients With Diabetic Nephropathy A Randomized Clinical Trial

JAMA-JOURNAL OF THE AMERICAN MEDICAL ASSOCIATION. Article. 314(9):884-894.
[doi:10.1001/jama.2015.10081]
Mahfoud, Felix, Boehm, Michael, Azizi, Michel, Pathak, Atul, Zaleski, Isabelle Durand, Ewen, Sebastian, Tsioufis, Kostantinos, Andersson, Bert, Blankestijn, Peter J., Burnier, Michel, Chatellier, Gilles, Gafoor, Sameer, Grassi, Guido, Joner, Michael, Kjeldsen, Sverre E., Luescher, Thomas Felix, Lobo, Melvin D., Lotan, Chaim, Parati, Gianfranco, Redon, Josep, Ruilope, Luis, Sudano, Isabella, Ukena, Christian, van Leeuwen, Evert, Volpe, Massimo, Windecker, Stephan, Witkowski, Adam, Wijns, William, Zeller, Thomas, Schmieder, Roland E. (2015).

Proceedings from the European clinical consensus conference for renal denervation: considerations on future clinical trial design

EUROPEAN HEART JOURNAL. Article. 36(33):2219-2227.
[doi:10.1093/eurheartj/ehv192]
Gil-Ortega M, García-Prieto CF, Ruiz-Hurtado G, Steireif C, González MC, Schulz A, Kreutz R, Fernández-Alfonso MS, Arribas S, Somoza B (2015).

Genetic predisposition to albuminuria is associated with increased arterial stiffness: role of elastin

BRITISH JOURNAL OF PHARMACOLOGY. Article. 172(17):4406-4418.
[doi:10.1111/bph.13223]
Catalina-Romero C, Ruilope LM, Sánchez-Chaparro MA, Valdivielso P, Cabrera-Sierra M, Fernández-Labandera C, Ruiz-Moraga M, Gonzalez-Quintela A, Calvo-Bonacho E (2015).

Factors influencing return-to-work after cerebrovascular disease: the importance of previous cardiovascular risk

European Journal of Preventive Cardiology. Article. 22(9):1220-1227.
[doi:10.1177/2047487314544961]
Galve E, Martell-Claros N, Camafort-Babkowski M, Grupo de consenso español sobre denervación renal (2015).

Renal denervation as treatment of resistant hypertension

MEDICINA CLINICA. Editorial Material. 145(3):131-135.
[doi:10.1016/j.medcli.2014.12.011]
Bavishi, Chirag, Messerli, Franz H., Kadosh, Bernard, Ruilope, Luis M., Kario, Kazuomi (2015).

Role of neprilysin inhibitor combinations in hypertension: insights from hypertension and heart failure trials

EUROPEAN HEART JOURNAL. Review. 36(30):1967-1973.
[doi:10.1093/eurheartj/ehv142]
Guijarro, Carlos, Miguel Ruilope, Luis (2015).

Cholesterol associated to low density lipoproteins (LDL) and vascular risk reduction. Proprotein convertase subtilisin/kexin type 9 (PCSK9): A new therapeutic target

MEDICINA CLINICA. Editorial Material. 145(2):67-69.
[doi:10.1016/j.medcli.2015.04.007]
Erdmann, Erland, Califf, Robert, Gerstein, Hertzel C., Malmberg, Klas, Ruilope, Luis, Schwartz, Gregory G., Wedel, Hans, Volz, Dietmar, Ditmarsch, Marc, Svensson, Anders, Bengus, Monica (2015).

Effects of the dual peroxisome proliferator-activated receptor activator aleglitazar in patients with Type 2 Diabetes mellitus or prediabetes

AMERICAN HEART JOURNAL. Article. 170(1):117-122.
[doi:10.1016/j.ahj.2015.03.021]
Delgado C, Ruiz-Hurtado G, Gómez-Hurtado N, González-Ramos S, Rueda A, Benito G, Prieto P, Zaragoza C, Delicado EG, Pérez-Sen R, Miras-Portugal MT, Núñez G, Boscá L, Fernández-Velasco M (2015).

NOD1, a new player in cardiac function and calcium handling

CARDIOVASCULAR RESEARCH. Article. 106(3):375-386.
[doi:10.1093/cvr/cvv118]
Mancia G, Mahfoud F, Narkiewicz K, Ruilope LM, Schlaich MP, Schmieder RE, Williams B, Böhm M (2015).

4A.01: LONG-TERM EFFECTS OF RENAL ARTERY DENERVATION IN REAL WORLD PATIENTS WITH UNCONTROLLED HYPERTENSION FROM THE GLOBAL SYMPLICITY REGISTRY.

JOURNAL OF HYPERTENSION. Article. 33 Suppl 1.
[doi:10.1097/01.hjh.0000467475.67073.7e]
Gorostidi M, Sarafidis P, Sierra Ade L, Banegas JR, De La Cruz JJ, Vinyoles E, Segura J, Ruilope LM (2015).

3D.02: BLOOD PRESSURE VARIABILITY INCREASES WITH ADVANCING CHRONIC KIDNEY DISEASE STAGE. A CROSS-SECTIONAL ANALYSIS OF 14,382 HYPERTENSIVE PATIENTS FROM SPAIN.

JOURNAL OF HYPERTENSION. Article. 33 Suppl 1.
[doi:10.1097/01.hjh.0000467455.93515.1e]
Pulido-Olmo H, Gracia-Prieto CF, Somoza B, Aránguez I, Alvarez-Llamas G, Vivanco F, Barderas MG, Kreutz R, Segura J, Fernández-Alfonso MS, Ruilope LM, Ruiz-Hurtado G (2015).

8D.08: MATRIX METALLOPROTEINASE (MMP) 2 AND MMP9 ACTIVITY IS INCREASED IN CONDITIONS OF ALBUMINURIA ESCAPE UNDER CHRONIC RENIN-ANGIOTENSIN SYSTEM SUPPRESSION.

JOURNAL OF HYPERTENSION. Article. 33 Suppl 1.
[doi:10.1097/01.hjh.0000467662.53908.09]
Mahfoud F, Linz D, Mancia G, Narkiewicz K, Ruilope LM, Schlaich MP, Schmieder RE, Williams B, Böhm M (2015).

8B.04: RENAL ARTERY DENERVATION FOR TREATMENT OF HYPERTENSIVE PATIENTS WITH OR WITHOUT OBSTRUCTIVE SLEEP APNEA AND RESISTANT HYPERTENSION: RESULTS FROM THE GLOBAL SYMPLICITY REGISTRY.

JOURNAL OF HYPERTENSION. Article. 33 Suppl 1.
[doi:10.1097/01.hjh.0000467640.39623.b2]
Banegas JR, de la Cruz JJ, Graciani A, López-García E, Gijón-Conde T, Ruilope LM, Rodriguez-Artalejo F (2015).

Impact of Ambulatory Blood Pressure Monitoring on Reclassification of Hypertension Prevalence and Control in Older People in Spain

Journal of Clinical Hypertension. Article. 17(6):453-461.
[doi:10.1111/jch.12525]
Boehm, Michael, Mahfoud, Felix, Ukena, Christian, Hoppe, Uta C., Narkiewicz, Krzysztof, Negoita, Manuela, Ruilope, Luis, Schlaich, Markus P., Schmieder, Roland E., Whitbourn, Robert, Williams, Bryan, Zeymer, Uwe, Zirlik, Andreas, Mancia, Giuseppe, GSR Investigators (2015).

First Report of the Global SYMPLICITY Registry on the Effect of Renal Artery Denervation in Patients With Uncontrolled Hypertension

HYPERTENSION. Article. 65(4):766-766.
[doi:10.1161/HYPERTENSIONAHA.114.05010]
Ruiz-Hurtado G, Ruilope LM (2015).

Cardiorenal protection during chronic renin-angiotensin-aldosterone system suppression: evidences and caveats

European Heart Journal-Cardiovascular Pharmacotherapy. Review. 1(2):126-131.
[doi:10.1093/ehjcvp/pvu023]
Martinez-Castelao, Alberto, Gorostidi, Manuel, Luis Gorriz, Jose, Santamaria Olmo, Rafael, Bover, Jordi, Segura, Julian (2015).

Reflections on two consensus documents about chronic kidney disease

NEFROLOGIA. Editorial Material. 35(2):127-130.
[doi:10.1016/j.nefro.2015.05.012]
García-Prieto CF, Hernández-Nuño F, Rio DD, Ruiz-Hurtado G, Aránguez I, Ruiz-Gayo M, Somoza B, Fernández-Alfonso MS (2015).

High-fat diet induces endothelial dysfunction through a down-regulation of the endothelial AMPK-PI3K-Akt-eNOS pathway

MOLECULAR NUTRITION & FOOD RESEARCH. Article. 59(3):520-532.
[doi:10.1002/mnfr.201400539]
de la Sierra, Alejandro, Oliveras, Anna, Armario, Pedro, Lucas, Silvia, Invest Estudio COMBICONTROL (2015).

Control of blood pressure in hypertensive patients on combination therapy

MEDICINA CLINICA. Article. 144(4):145-150.
[doi:10.1016/j.medcli.2013.09.033]
García-Prieto CF, Pulido-Olmo H, Ruiz-Hurtado G, Gil-Ortega M, Aranguez I, Rubio MA, Ruiz-Gayo M, Somoza B, Fernández-Alfonso MS (2015).

Mild caloric restriction reduces blood pressure and activates endothelial AMPK-PI3K-Akt-eNOS pathway in obese Zucker rats

VASCULAR PHARMACOLOGY. Article. 65-66:3-12.
[doi:10.1016/j.vph.2014.12.001]
Mahfoud F, Ruilope LM, Böhm M, Schmieder RE (2015).

Aldosterone Antagonists and Renal Denervation Friends or Foes?

HYPERTENSION. Editorial Material. 65(2):280-282.
[doi:10.1161/HYPERTENSIONAHA.114.04119]
Ruilope, Luis, Schaefer, Angie (2015).

The Fixed-Dose Combination of Olmesartan/Amlodipine Was Superior in Central Aortic Blood Pressure Reduction Compared with Perindopril/Amlodipine: A Randomized, Double-Blind Trial in Patients with Hypertension (vol 30, pg 1086, 2013)

ADVANCES IN THERAPY. Correction. 32(2):184-185.
[doi:10.1007/s12325-015-0186-4]
Tamargo, J., Duarte, J., Ruilope, L. M. (2015).

New Antihypertensive Drugs Under Development

CURRENT MEDICINAL CHEMISTRY. Article. 22(3):305-342.
Banegas JR, Navarro-Vidal B, Ruilope LM, de la Cruz JJ, López-García E, Rodríguez-Artalejo F, Graciani A (2015).

Trends in Hypertension Control Among the Older Population of Spain From 2000 to 2001 to 2008 to 2010 Role of Frequency and Intensity of Drug Treatment

Circulation-Cardiovascular Quality and Outcomes. Article. 8(1):67-76.
[doi:10.1161/CIRCOUTCOMES.114.001191]
Sarafidis, P. A., Ruilope, L. M. (2015).

European Society of Hypertension Scientific Newsletter: Update on Hypertension Management 2013; 14: Nr. 56* Renin-Angiotensin-Aldosterone System Blockade in Hypertensive Patients with Chronic Kidney Disease

Journal fur Hypertonie. Article. 19(1):16-20.

2014

Banegas JR, Ruilope LM, de la Sierra A, de la Cruz JJ, Gorostidi M, Segura J, Martell N, García-Puig J, Deanfield J, Williams B (2014).

High prevalence of masked uncontrolled hypertension in people with treated hypertension

EUROPEAN HEART JOURNAL. Article. 35(46):3304-3312.
[doi:10.1093/eurheartj/ehu016]
Ruiz-Hurtado G, Ruilope LM (2014).

Does cardiovascular protection translate into renal protection?

NATURE REVIEWS CARDIOLOGY. Article. 11(12):742-746.
[doi:10.1038/nrcardio.2014.97]
Ruilope L, Hanefeld M, Lincoff AM, Viberti G, Meyer-Reigner S, Mudie N, Wieczorek Kirk D, Malmberg K, Herz M (2014).

Effects of the dual peroxisome proliferator-activated receptor-alpha/gamma agonist aleglitazar on renal function in patients with stage 3 chronic kidney disease and type 2 diabetes: a Phase IIb, randomized study

BMC Nephrology. Article. 15:180-180.
[doi:10.1186/1471-2369-15-180]
Pereira L, Ruiz-Hurtado G, Rueda A, Mercadier JJ, Benitah JP, Gómez AM (2014).

Calcium signaling in diabetic cardiomyocytes

CELL CALCIUM. Review. 56(5, SI):372-380.
[doi:10.1016/j.ceca.2014.08.004]
Fernández-Velasco M, Ruiz-Hurtado G, Gómez AM, Rueda A (2014).

Ca2+ handling alterations and vascular dysfunction in diabetes

CELL CALCIUM. Review. 56(5, SI):397-407.
[doi:10.1016/j.ceca.2014.08.007]
Raff, Ulrike, Ott, Christian, Ruilope, Luis M., Menne, Jan, Haller, Hermann, Schmieder, Roland E. (2014).

Prevention of electrocardiographic left ventricular remodeling by the angiotensin receptor blocker olmesartan in patients with type 2 diabetes

JOURNAL OF HYPERTENSION. Article. 32(11):2267-2276.
[doi:10.1097/HJH.0000000000000313]
Ruilope, Luis M., Arribas, Fernando (2014).

Resistant Hypertension and Renal Denervation. Considerations on the Results of the Symplicity HTN-3 Trial

REVISTA ESPANOLA DE CARDIOLOGIA. Editorial Material. 67(11):881-882.
[doi:10.1016/j.rec.2014.06.017]
Brotons, Carlos, Calvo-Bonacho, Eva, Moral, Irene, Teresa Garcia-Margallo, Maria, Victoria Cortes-Arcas, Maria, Puig, Mireia, Vazquez-Pirillo, Gaston, Miguel Ruilope, Luis (2014).

Impact of the New American and British Guidelines on the Management and Treatment of Dyslipidemia in a Spanish Working Population

REVISTA ESPANOLA DE CARDIOLOGIA. Article. 67(11):906-911.
[doi:10.1016/j.rec.2014.06.018]
Ruiz-Hurtado G, Condezo-Hoyos L, Pulido-Olmo H, Aranguez I, Del Carmen Gónzalez M, Arribas S, Cerezo C, Segura J, Praga M, Fernández-Alfonso MS, Ruilope LM (2014).

Development of albuminuria and enhancement of oxidative stress during chronic renin-angiotensin system suppression

JOURNAL OF HYPERTENSION. Article. 32(10):2082-2091.
[doi:10.1097/HJH.0000000000000292]
Sarafidis, Pantelis A., Ruilope, Luis M. (2014).

Lower blood pressure target in nondiabetic proteinuric chronic kidney disease is not justified Reply

KIDNEY INTERNATIONAL. Letter. 86(4):855-855.
[doi:10.1038/ki.2014.172]
Vinyoles E, Sierra Ade L, Roso A, Cruz JJ, Gorostidi M, Segura J, Banegas JR, Martell-Claros N, Ruilope LM (2014).

Contribution of the ABP-International study to the definition of night-time tachycardia Reply

JOURNAL OF HYPERTENSION. Letter. 32(10):2101-2101.
[doi:10.1097/HJH.0000000000000335]
Sanchez-Chaparro, Miguel-Angel, Calvo-Bonacho, Eva, Gonzalez-Quintela, Arturo, Cabrera, Martha, Quevedo-Aguado, Luis, Fernandez-Labandera, Carlos, Ruiz-Moraga, Montserrat, Carlos Sainz-Gutierrez, Juan, Gomez-Martinez, Pablo, Roman-Garcia, Javier, Valdivielso Felices, Pedro, Ruilope, Luis-Miguel, Zanchetti, Alberto, ICARIA Ibermutuamur CArdiovasc (2014).

Estimating the glomerular filtration rate in the Spanish working population: chronic kidney disease prevalence and its association with risk factors

JOURNAL OF HYPERTENSION. Article. 32(10):1970-1978.
[doi:10.1097/HJH.0000000000000267]
Gonzalez Albarran, O., Gorostidi, M., Segura, J., Ruilope, L. (2014).

Diabetes and ambulatory blood pressure monitoring: a cross-sectional analysis of 68045 hypertensive patients in Spain

DIABETOLOGIA. Meeting Abstract. 57(1):94-94.
Ruilope, L. M., Calvo-Bonacho, E., Sanchez-Chaparro, M. A., Cabrera Sierra, M., Quevedo-Aguado, L., Fernandez-Labandera, C., Ruiz-Moraga, M., Sainz-Gutierrez, J. C., Gonzalez-Quintela, A., Valdivielso-Felices, P. (2014).

Study of associations between chronic kidney disease and cardiovacular and metabolic risk factors in the working population

EUROPEAN HEART JOURNAL. Meeting Abstract. 35(1):366-366.
Zanchetti A, Liu L, Mancia G, Parati G, Grassi G, Stramba-Badiale M, Silani V, Bilo G, Corrao G, Zambon A, Scotti L, Zhang X, Wang H, Zhang Y, Zhang X, Guan TR, Berge E, Redon J, Narkiewicz K, Dominiczak A, Nilsson P, Viigimaa M, Laurent S, Agabiti-Rosei E, Wu Z, Zhu D, Rodicio JL, Ruilope LM, Martell-Claros N, Pinto F, Schmieder RE, Burnier M, Banach M, Cifkova R, Farsang C, Konradi A, Lazareva I, Sirenko Y, Dorobantu M, Postadzhiyan A, Accetto R, Jelakovic B, Lovic D, Manolis AJ, Stylianou P, Erdine S, Dicker D, Wei G, Xu C, Xie H, Coca A, O'Brien J, Ford G (2014).

Blood pressure and LDL-cholesterol targets for prevention of recurrent strokes and cognitive decline in the hypertensive patient: design of the European Society of Hypertension-Chinese Hypertension League Stroke in Hypertension Optimal Treatment randomized trial

JOURNAL OF HYPERTENSION. Article. 32(9):1888-1897.
[doi:10.1097/HJH.0000000000000254]
Zanchetti A, Liu L, Mancia G, Parati G, Grassi G, Stramba-Badiale M, Silani V, Bilo G, Corrao G, Zambon A, Scotti L, Zhang X, Wang H, Zhang Y, Zhang X, Guan TR, Berge E, Redon J, Narkiewicz K, Dominiczak A, Nilsson P, Viigimaa M, Laurent S, Agabiti-Rosei E, Wu Z, Zhu D, Rodicio JL, Ruilope LM, Martell-Claros N, Pinto F, Schmieder RE, Burnier M, Banach M, Cifkova R, Farsang C, Konradi A, Lazareva I, Sirenko Y, Dorobantu M, Postadzhiyan A, Accetto R, Jelakovic B, Lovic D, Manolis AJ, Stylianou P, Erdine S, Dicker D, Wei G, Xu C, Xie H, Coca A, O'Brien J, Ford G (2014).

Blood pressure and low-density lipoprotein-cholesterol lowering for prevention of strokes and cognitive decline: a review of available trial evidence

JOURNAL OF HYPERTENSION. Review. 32(9):1741-1750.
[doi:10.1097/HJH.0000000000000253]
Ruilope, L. M., Izzo, Jr., J. L., Conde, L. G., Zappe, D. H., Zhang, Y., Zhang, J. (2014).

Efficacy of LCZ696, an angiotensin receptor neprilysin inhibitor (ARNI), in obese and overweight subjects with hypertension

EUROPEAN HEART JOURNAL. Meeting Abstract. 35(1):65-65.
Ruilope, L. M., Izzo, Jr., J. L., Conde, L. G., Zappe, D. H., Zhang, Y., Zhang, J. (2014).

Comparative efficacy of valsartan and LCZ696, an angiotensin receptor neprilysin inhibitor (ARNI), in hypertensive individuals: effects of gender

EUROPEAN HEART JOURNAL. Meeting Abstract. 35(1):571-571.
Ruilope, L. M., SEVITENSION Study Investigators (2014).

Fixed-combination olmesartan/amlodipine (OLM/AML) was superior to perindopril plus amlodipine (PER/AML) in reducing central systolic blood pressure (CSBP) in hypertensive patients with diabetes

EUROPEAN HEART JOURNAL. Meeting Abstract. 35(1):572-572.
Waeber B, Volpe M, Ruilope LM, Schmieder RE (2014).

Diagnosis and treatment of resistant hypertension

BLOOD PRESSURE. Article. 23(4):193-199.
[doi:10.3109/08037051.2013.854946]
Ruilope, Luis (2014).

Additional Information Regarding the SEVITENSION Study

ADVANCES IN THERAPY. Letter. 31(8):777-779.
[doi:10.1007/s12325-014-0144-6]
Fernández-Alfonso MS, Ruilope LM (2014).

One Step Forward for Serelaxin as a Promising Therapy in Cardiac Fibrosis

HYPERTENSION. Editorial Material. 64(2):229-230.
[doi:10.1161/HYPERTENSIONAHA.114.03642]
Segura J, Ruilope LM (2014).

Long-term blockade of the renin-angiotensin system: an adequate evaluation is still needed

HYPERTENSION RESEARCH. Editorial Material. 37(8):701-702.
[doi:10.1038/hr.2014.87]
Ruiz-Hurtado G, Ruilope LM (2014).

Hypertension and Obesity: Correlates With Renin-Angiotensin-Aldosterone System and Uric Acid

Journal of Clinical Hypertension. Editorial Material. 16(8):559-560.
[doi:10.1111/jch.12356]
Ruilope LM (2014).

Renin-angiotensin system blockade: time for a reappraisal?

EUROPEAN HEART JOURNAL. Editorial Material. 35(26):1703-1705.
[doi:10.1093/eurheartj/ehu129]
de la Sierra A, Calhoun DA, Vinyoles E, Banegas JR, de la Cruz JJ, Gorostidi M, Segura J, Ruilope LM (2014).

Heart rate and heart rate variability in resistant versus controlled hypertension and in true versus white-coat resistance

JOURNAL OF HUMAN HYPERTENSION. Article. 28(7):416-420.
[doi:10.1038/jhh.2013.135]
Parati G, Stergiou G, O'Brien E, Asmar R, Beilin L, Bilo G, Clement D, de la Sierra A, de Leeuw P, Dolan E, Fagard R, Graves J, Head GA, Imai Y, Kario K, Lurbe E, Mallion JM, Mancia G, Mengden T, Myers M, Ogedegbe G, Ohkubo T, Omboni S, Palatini P, Redon J, Ruilope LM, Shennan A, Staessen JA, vanMontfrans G, Verdecchia P, Waeber B, Wang J, Zanchetti A, Zhang Y (2014).

European Society of Hypertension practice guidelines for ambulatory blood pressure monitoring

JOURNAL OF HYPERTENSION. Article. 32(7):1359-1366.
[doi:10.1097/HJH.0000000000000221]
Ruilope, Luis M. (2014).

Was there real denervation in the SYMPLICITY HTN-3 trial?

EUROPEAN HEART JOURNAL. Editorial Material. 35(26):1699-1700.
Hernández Díaz FJ, Ruilope LM (2014).

Is it useful to determine the cardiovascular risk at 30 years?

MEDICINA CLINICA. Editorial Material. 142(12):540-541.
[doi:10.1016/j.medcli.2014.01.020]
Kjeldsen SE, Aksnes TA, Ruilope LM (2014).

Clinical implications of the 2013 ESH/ESC hypertension guidelines: targets, choice of therapy, and blood pressure monitoring.

DRUGS IN R&D. Article. 14(2):31-43.
[doi:10.1007/s40268-014-0049-5]
Ruilope LM (2014).

Arterial Function and Cardiorenal Damage

Journal of Clinical Hypertension. Editorial Material. 16(6):398-398.
[doi:10.1111/jch.12318]
Gorostidi M, Santamaría R, Alcázar R, Fernández-Fresnedo G, Galcerán JM, Goicoechea M, Oliveras A, Portolés J, Rubio E, Segura J, Aranda P, de Francisco AL, Del Pino MD, Fernández-Vega F, Górriz JL, Luño J, Marín R, Martínez I, Martínez-Castelao A, Orte LM, Quereda C, Rodríguez-Pérez JC, Rodríguez M, Ruilope LM (2014).

Spanish Society of Nephrology document on KDIGO guidelines for the assessment and treatment of chronic kidney disease

NEFROLOGIA. Article. 34(3):302-316.
[doi:10.3265/Nefrologia.pre2014.Feb.12464]
Vinyoles E, de la Sierra A, Roso A, de la Cruz JJ, Gorostidi M, Segura J, Banegas JR, Martell-Claros N, Ruilope LM (2014).

Night-time heart rate cut-off point definition by resting office tachycardia in untreated hypertensive patients: data of the Spanish ABPM registry

JOURNAL OF HYPERTENSION. Article. 32(5):1016-1024.
[doi:10.1097/HJH.0000000000000124]
Menne, Jan, Ritz, Eberhard, Ruilope, Luis M., Chatzikyrkou, Christos, Viberti, Giancarlo, Haller, Hermann (2014).

ROADMAP OBSERVATIONAL FOLLOW-UP STUDY: BENEFITS OF RAAS BLOCKADE WITH OLMESARTAN TREATMENT ARE SUSTAINED AFTER STUDY DISCONTINUATION

NEPHROLOGY DIALYSIS TRANSPLANTATION. Meeting Abstract. 29(3):52-52.
Tamargo, Juan, Solini, Anna, Ruilope, Luis M. (2014).

Comparison of Agents That Affect Aldosterone Action

SEMINARS IN NEPHROLOGY. Review. 34(3):285-306.
[doi:10.1016/j.semnephrol.2014.04.005]
Ruilope, Luis M. (2014).

Can we make an adequate estimation of urinary sodium excretion avoiding 24-h urine collection?

JOURNAL OF HYPERTENSION. Editorial Material. 32(5):977-977.
[doi:10.1097/HJH.0000000000000153]
Schlaich, Markus, Ruilope, Luis, Schmieder, Roland, Mancia, Giuseppe, Mahfoud, Felix, Boehm, Michael (2014).

BLOOD PRESSURE AND RENAL FUNCTION AFTER RENAL DENERVATION: INSIGHTS FROM THE GLOBAL SYMPLICITY REGISTRY

AMERICAN JOURNAL OF KIDNEY DISEASES. Meeting Abstract. 63(5):98-98.
de la Sierra, Alejandro, Gorostidi, Manuel, Banegas, Jose R., Segura, Julian, de la Cruz, Juan J., Ruilope, Luis M. (2014).

Nocturnal Hypertension or Nondipping: Which Is Better Associated With the Cardiovascular Risk Profile?

AMERICAN JOURNAL OF HYPERTENSION. Article. 27(5):680-687.
[doi:10.1093/ajh/hpt175]
Tamargo, Juan, Segura, Julian, Ruilope, Luis M. (2014).

Diuretics in the treatment of hypertension. Part 2: loop diuretics and potassium-sparing agents

EXPERT OPINION ON PHARMACOTHERAPY. Review. 15(5):605-621.
[doi:10.1517/14656566.2014.879117]
Ruilope, Luis, Schaefer, Angie (2014).

The Fixed-Dose Combination of Olmesartan/Amlodipine Was Superior in Central Aortic Blood Pressure Reduction Compared with Perindopril/Amlodipine: A Randomized, Double-Blind Trial in Patients with Hypertension (vol 30 pg 1086, 2013)

ADVANCES IN THERAPY. Correction. 31(4):472-472.
[doi:10.1007/s12325-014-0113-0]
Ruilope, Luis M. (2014).

Blood Pressure and Uric Acid in Diabetes Mellitus

Journal of Clinical Hypertension. Editorial Material. 16(4):269-269.
[doi:10.1111/jch.12298]
Menne J, Ritz E, Ruilope LM, Chatzikyrkou C, Viberti G, Haller H (2014).

The Randomized Olmesartan and Diabetes Microalbuminuria Prevention (ROADMAP) Observational Follow-Up Study: Benefits of RAS Blockade With Olmesartan Treatment Are Sustained After Study Discontinuation

JOURNAL OF THE AMERICAN HEART ASSOCIATION. Article. 3(2).
[doi:10.1161/JAHA.114.000810]
Schmieder RE, Volpe M, Waeber B, Ruilope LM (2014).

A guide for easy- and difficult-to-treat hypertension

International Journal of Cardiology. Review. 172(1):17-22.
[doi:10.1016/j.ijcard.2013.12.125]
Tamargo, Juan, Segura, Julian, Ruilope, Luis M. (2014).

Diuretics in the treatment of hypertension. Part 1: thiazide and thiazide-like diuretics

EXPERT OPINION ON PHARMACOTHERAPY. Review. 15(4):527-547.
[doi:10.1517/14656566.2014.879118]
Sarafidis, Pantelis A., Ruilope, Luis M. (2014).

Aggressive blood pressure reduction and renin-angiotensin system blockade in chronic kidney disease: time for re-evaluation?

KIDNEY INTERNATIONAL. Review. 85(3):536-546.
[doi:10.1038/ki.2013.355]
Bakris, George, Sarafidis, Pantelis, Agarwal, Rajiv, Ruilope, Luis (2014).

Review of blood pressure control rates and outcomes

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION. Review. 8(2):127-141.
[doi:10.1016/j.jash.2013.07.009]
Mancia, Giuseppe, Fagard, Robert, Narkiewicz, Krzysztof, Redon, Josep, Zanchetti, Alberto, Boehm, Michael, Christiaens, Thierry, Cifkova, Renata, De Backer, Guy, Dominiczak, Anna, Galderisi, Maurizio, Grobbee, Diederick E., Jaarsma, Tiny, Kirchhof, Paulus, Kjeldsen, Sverre E., Laurent, Stephane, Manolis, Athanasios J., Nilsson, Peter M., Ruilope, Luis Miguel, Schmieder, Roland E., Sirnes, Per Anton, Sleight, Peter, Viigimaa, Margus, Waeber, Bernard, Zannad, Faiez, ESH, ESC (2014).

2013 ESH/ESC Practice Guidelines for the Management of Arterial Hypertension

BLOOD PRESSURE. Article. 23(1):3-16.
[doi:10.3109/08037051.2014.868629]
Calvo-Bonacho E, Ruilope LM, Sánchez-Chaparro MA, Cerezo C, Catalina-Romero C, Martínez-Muñoz P, Banegas JR, Waeber B, Gonzalez-Quintela A, Zanchetti A (2014).

Influence of high cardiovascular risk in asymptomatic people on the duration and cost of sick leave: results of the ICARIA study

EUROPEAN HEART JOURNAL. Article. 35(5):299-306.
[doi:10.1093/eurheartj/eht156]
Ruilope L, Schaefer A (2014).

The Fixed-Dose Combination of Olmesartan/Amlodipine Was Superior in Central Aortic Blood Pressure Reduction Compared with Perindopril/Amlodipine: A Randomized, Double-Blind Trial in Patients with Hypertension (vol 30, pg 1086, 2013)

ADVANCES IN THERAPY. Correction. 31(2):243-243.
[doi:10.1007/s12325-014-0097-9]
Ruilope LM, Agarwal R, Chan JC, Cooper ME, Gansevoort RT, Haller H, Remuzzi G, Rossing P, Schmieder RE, Nowack C, Ferreira AC, Pieper A, Kimmeskamp-Kirschbaum N, Bakris GL (2014).

Rationale, Design, and Baseline Characteristics of ARTS-DN: A Randomized Study to Assess the Safety and Efficacy of Finerenone in Patients with Type 2 Diabetes Mellitus and a Clinical Diagnosis of Diabetic Nephropathy

AMERICAN JOURNAL OF NEPHROLOGY. Article. 40(6):572-581.
[doi:10.1159/000371497]
Ruilope LM (2014).

Understanding Visit-to-Visit Blood Pressure Variability

Journal of Clinical Hypertension. Editorial Material. 16(1):8-9.
[doi:10.1111/jch.12231]
Segura J, Banegas JR, Ruilope LM (2014).

Usefulness of ambulatory blood pressure monitoring (ABPM) in daily clinical practice: Data from the Spanish ABPM registry

CLINICAL AND EXPERIMENTAL PHARMACOLOGY AND PHYSIOLOGY. Article. 41(1):30-36.
[doi:10.1111/1440-1681.12126]

2013

Schlaich, Markus P., Schmieder, Roland E., Bakris, George, Blankestijn, Peter J., Boehm, Michael, Campese, Vito M., Francis, Darrel P., Grassi, Guido, Hering, Dagmara, Katholi, Richard, Kjeldsen, Sverre, Krum, Henry, Mahfoud, Felix, Mancia, Giuseppe, Messerli, Franz H., Narkiewicz, Krzysztof, Parati, Gianfranco, Rocha-Singh, Krishna J., Ruilope, Luis M., Rump, Lars C., Sica, Domenic A., Sobotka, Paul A., Tsioufis, Costas, Vonend, Oliver, Weber, Michael A., Williams, Bryan, Zeller, Thomas, Esler, Murray D. (2013).

International Expert Consensus Statement Percutaneous Transluminal Renal Denervation for the Treatment of Resistant Hypertension

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Review. 62(22):2031-2045.
[doi:10.1016/j.jacc.2013.08.1616]
Sarafidis, Pantelis A., Ruilope, Luis M. (2013).

BLOOD PRESSURE TARGETS FOR PATIENTS WITH CHRONIC KIDNEY DISEASE

BLOOD PRESSURE. News Item. 22(6):395-396.
[doi:10.3109/08037051.2013.852375]
Schmieder RE, Ruilope LM, Ott C, Mahfoud F, Böhm M (2013).

Interpreting treatment-induced blood pressure reductions measured by ambulatory blood pressure monitoring

JOURNAL OF HUMAN HYPERTENSION. Review. 27(12):715-720.
[doi:10.1038/jhh.2013.39]
Herz, Matthias, Malmberg, Klas, Hanefeld, Markolf, Ruilope, Luis, Lincoff, A. Michael, Viberti, Giancarlo, Mudie, Nadejda, Urbanowska, Teresa, Reigner, Sylvie Meyer (2013).

EFFECTS OF ALEGLITAZAR ON CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH STAGE 3 CHRONIC KIDNEY DISEASE AND TYPE 2 DIABETES

ATHEROSCLEROSIS. Meeting Abstract. 231(2):3-3.
[doi:10.1016/j.atherosclerosis.2013.07.015]
Ruilope L, Schaefer A (2013).

The Fixed-Dose Combination of Olmesartan/Amlodipine Was Superior in Central Aortic Blood Pressure Reduction Compared with Perindopril/Amlodipine: A Randomized, Double-Blind Trial in Patients with Hypertension

ADVANCES IN THERAPY. Article. 30(12):1086-1099.
[doi:10.1007/s12325-013-0076-6]
Sarafidis, Pantelis A., Ruilope, Luis M. (2013).

RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM BLOCKADE IN HYPERTENSIVE PATIENTS WITH CHRONIC KIDNEY DISEASE

BLOOD PRESSURE. News Item. 22(6):397-398.
[doi:10.3109/08037051.2013.852376]
Steireif C, García-Prieto CF, Ruiz-Hurtado G, Pulido-Olmo H, Aranguez I, Gil-Ortega M, Somoza B, Schönfelder G, Schulz A, Fernández-Alfonso MS, Kreutz R (2013).

Dissecting the genetic predisposition to albuminuria and endothelial dysfunction in a genetic rat model

JOURNAL OF HYPERTENSION. Article. 31(11):2203-2212.
[doi:10.1097/HJH.0b013e3283642384]
Sierra, Cristina, Miguel Ruilope, Luis (2013).

Effectiveness of antihypertensive treatment and control of blood pressure: Is it improvable?

MEDICINA CLINICA. Editorial Material. 141(8):343-345.
[doi:10.1016/j.medcli.2013.04.044]
Segura J, de la Sierra A, Fernández S, Ruilope LM (2013).

Relevance of diabetes in high cardiovascular risk hypertensive patients

MEDICINA CLINICA. Article. 141(7):287-291.
[doi:10.1016/j.medcli.2012.05.032]
Ruilope LM (2013).

CHRONIC KIDNEY DISEASE Blood pressure control in CKD-still a matter of debate

NATURE REVIEWS NEPHROLOGY. News Item. 9(10):572-573.
[doi:10.1038/nrneph.2013.180]
Ruilope LM (2013).

Long-term adherence to therapy: the clue to prevent hypertension consequences

EUROPEAN HEART JOURNAL. Editorial Material. 34(38, SI):2931-2932.
[doi:10.1093/eurheartj/eht299]
Zannad, Faiez, Garcia, Angeles Alonso, Anker, Stefan D., Armstrong, Paul W., Calvo, Gonzalo, Cleland, John G. F., Cohn, Jay N., Dickstein, Kenneth, Domanski, Michael J., Ekman, Inger, Filippatos, Gerasimos S., Gheorghiade, Mihai, Hernandez, Adrian F., Jaarsma, Tiny, Koglin, Joerg, Konstam, Marvin, Kupfer, Stuart, Maggioni, Aldo P., Mebazaa, Alexandre, Metra, Marco, Nowack, Christina, Pieske, Burkert, Pina, Ileana L., Pocock, Stuart J., Ponikowski, Piotr, Rosano, Giuseppe, Ruilope, Luis M., Ruschitzka, Frank, Severin, Thomas, Solomon, Scott, Stein, Kenneth, Stockbridge, Norman L., Stough, Wendy Gattis, Swedberg, Karl, Tavazzi, Luigi, Voors, Adriaan A., Wasserman, ScottM., Woehrle, Holger, Zalewski, Andrew, McMurray, John J. V. (2013).

Clinical outcome endpoints in heart failure trials: a European Society of Cardiology Heart Failure Association consensus document

EUROPEAN JOURNAL OF HEART FAILURE. Review. 15(10):1082-1094.
[doi:10.1093/eurjhf/hft095]
Mancia, Giuseppe, Fagard, Robert, Narkiewicz, Krzysztof, Redon, Josep, Zanchetti, Alberto, Boehm, Michael, Christiaens, Thierry, Cifkova, Renata, De Backer, Guy, Dominiczak, Anna, Galderisi, Maurizio, Grobbee, Diederick E., Jaarsma, Tiny, Kirchof, Paulus, Kjeldsen, Sverre E., Laurent, Stephane, Manolis, Athanasios J., Nilsson, Peter M., Miguel Ruilope, Luis, Schmieder, Roland E., Sirnes, Per Anton, Sleight, Peter, Viigimaa, Margus, Waeber, Bernard, Zannad, Faiez (2013).

2013 Practice guidelines for the management of arterial hypertension of the European Society of Hypertension (ESH) and the European Society of Cardiology (ESC)

JOURNAL OF HYPERTENSION. Article. 31(10):1925-1938.
[doi:10.1097/HJH.0b013e328364ca4c]
Fontenla, Adolfo, Garcia-Donaire, Jose A., Ruilope, Luis M., Arribas, Fernando (2013).

Comment on the Management of Resistant Hypertension in a Multidisciplinary Unit of Renal Denervation: Protocol and Results. Response

REVISTA ESPANOLA DE CARDIOLOGIA. Letter. 66(10):830-831.
[doi:10.1016/j.rec.2013.06.003]
Mentz RJ, Bakris GL, Waeber B, McMurray JJ, Gheorghiade M, Ruilope LM, Maggioni AP, Swedberg K, Piña IL, Fiuzat M, O'Connor CM, Zannad F, Pitt B (2013).

The past, present and future of renin-angiotensin aldosterone system inhibition

International Journal of Cardiology. Review. 167(5):1677-1687.
[doi:10.1016/j.ijcard.2012.10.007]
O'Brien, Eoin, Parati, Gianfranco, Stergiou, George, Asmar, Roland, Beilin, Laurie, Bilo, Grzegorz, Clement, Denis, de la Sierra, Alejandro, de Leeuw, Peter, Dolan, Eamon, Fagard, Robert, Graves, John, Head, Geoffrey A., Imai, Yutaka, Kario, Kazuomi, Lurbe, Empar, Mallion, Jean-Michel, Mancia, Giuseppe, Mengden, Thomas, Myers, Martin, Ogedegbe, Gbenga, Ohkubo, Takayoshi, Omboni, Stefano, Palatini, Paolo, Redon, Josep, Ruilope, Luis M., Shennan, Andrew, Staessen, Jan A., vanMontfrans, Gert, Verdecchia, Paolo, Waeber, Bernard, Wang, Jiguang, Zanchetti, Alberto, Zhang, Yuqing, European Soc Hypertension Working (2013).

European Society of Hypertension Position Paper on Ambulatory Blood Pressure Monitoring

JOURNAL OF HYPERTENSION. Article. 31(9):1731-1768.
[doi:10.1097/HJH.0b013e328363e964]
Boehm, Michael, Mahfoud, Felix, Ukena, Christian, Bauer, Axel, Fleck, Eckart, Hoppe, Uta C., Kintscher, Ulrich, Narkiewicz, Krzysztof, Negoita, Manuela, Ruilope, Luis, Rump, L. Christian, Schlaich, Markus, Schmieder, Roland, Sievert, Horst, Weil, Joachim, Williams, Bryan, Zeymer, Uwe, Mancia, Giuseppe (2013).

Rationale and design of a large registry on renal denervation: the Global SYMPLICITY registry

EuroIntervention. Article. 9(4):484-492.
[doi:10.4244/EIJV9I4A78]
Gorostidi, Manuel, Sarafidis, Pantelis A., de la Sierra, Alejandro, Segura, Julian, de la Cruz, Juan J., Banegas, Jose R., Ruilope, Luis M., Spanish ABPM Registry Investigator (2013).

Differences Between Office and 24-Hour Blood Pressure Control in Hypertensive Patients With CKD: A 5,693-Patient Cross-sectional Analysis From Spain

AMERICAN JOURNAL OF KIDNEY DISEASES. Article. 62(2):285-294.
[doi:10.1053/j.ajkd.2013.03.025]
Mancia, Giuseppe, Fagard, Robert, Narkiewicz, Krzysztof, Redon, Josep, Zanchetti, Alberto, Boehm, Michael, Christiaens, Thierry, Cifkova, Renata, De Backer, Guy, Dominiczak, Anna, Galderisi, Maurizio, Grobbee, Diederick E., Jaarsma, Tiny, Kirchhof, Paulus, Kjeldsen, Sverre E., Laurent, Stephane, Manolis, Athanasios J., Nilsson, Peter M., Miguel Ruilope, Luis, Schmieder, Roland E., Sirnes, Per Anton, Sleight, Peter, Viigimaa, Margus, Waeber, Bernard, Zannad, Faiez, Luis Zamorano, Jose, Achenbach, Stephan, Baumgartner, Helmut, Bax, Jeroen J., Bueno, Hector, Dean, Veronica, Deaton, Christi, Erol, Cetin, Fagard, Robert, Ferrari, Roberto, Hasdai, David, Hoes, Arno W., Kirchhof, Paulus, Knuuti, Juhani, Kolh, Philippe, Lancellotti, Patrizio, Linhart, Ales, Nihoyannopoulos, Petros, Piepoli, Massimo F., Ponikowski, Piotr, Sirnes, Per Anton, Luis Tamargo, Juan, Tendera, Michal, Torbicki, Adam, Wijns, William, Windecker, Stephan, European Soc Hypertension, European Soc Cardiology (2013).

2013 ESH/ESC Guidelines for the management of arterial hypertension

BLOOD PRESSURE. Article. 22(4):193-278.
[doi:10.3109/08037051.2013.812549]
Ruilope LM, Arribas F (2013).

Resistant hypertension: From prevention to renal denervation

MEDICINA CLINICA. Editorial Material. 141(1):27-28.
[doi:10.1016/j.medcli.2012.11.023]
Gomez, Ana M., Ruiz-Hurtado, Gema, Benitah, Jean-Pierre, Dominguez-Rodriguez, Alejandro (2013).

Ca2+ Fluxes Involvement in Gene Expression During Cardiac Hypertrophy

Current Vascular Pharmacology. Article. 11(4):497-506.
[doi:10.2174/1570161111311040013]
Mancia, Giuseppe, Fagard, Robert, Narkiewicz, Krzysztof, Redon, Josep, Zanchetti, Alberto, Boehm, Michael, Christiaens, Thierry, Cifkova, Renata, De Backer, Guy, Dominiczak, Anna, Galderisi, Maurizio, Grobbee, Diederick E., Jaarsma, Tiny, Kirchhof, Paulus, Kjeldsen, Sverre E., Laurent, Stephane, Manolis, Athanasios J., Nilsson, Peter M., Ruilope, Luis Miguel, Schmieder, Roland E., Sirnes, Per Anton, Sleight, Peter, Viigimaa, Margus, Waeber, Bernard, Zannad, Faiez, Task Force Members (2013).

2013 ESH/ESC Guidelines for the management of arterial hypertension

EUROPEAN HEART JOURNAL. Review. 34(28):2159-2219.
[doi:10.1093/eurheartj/eht151]
Mancia, Giuseppe, Fagard, Robert, Narkiewicz, Krzysztof, Redon, Josep, Zanchetti, Alberto, Boehm, Michael, Christiaens, Thierry, Cifkova, Renata, De Backer, Guy, Dominiczak, Anna, Galderisi, Maurizio, Grobbee, Diederick E., Jaarsma, Tiny, Kirchhof, Paulus, Kjeldsen, Sverre E., Laurent, Stephane, Manolis, Athanasios J., Nilsson, Peter M., Ruilope, Luis Miguel, Schmieder, Roland E., Sirnes, Per Anton, Sleight, Peter, Viigimaa, Margus, Waeber, Bernard, Zannad, Faiez (2013).

2013 ESH/ESC Guidelines for themanagement of arterial hypertension The Task Force for the management ofarterial hypertension of the European Society ofHypertension (ESH) and of the European Society of Cardiology (ESC)

JOURNAL OF HYPERTENSION. Article. 31(7):1281-1357.
[doi:10.1097/01.hjh.0000431740.32696.cc]
Segura J, Salazar J, Ruilope LM (2013).

Dual neurohormonal intervention in CV disease: angiotensin receptor and Neprilysin inhibition

EXPERT OPINION ON INVESTIGATIONAL DRUGS. Editorial Material. 22(7):915-925.
[doi:10.1517/13543784.2013.797962]
Cerezo C, Segura J, Praga M, Ruilope LM (2013).

Guidelines Updates in the Treatment of Obesity or Metabolic Syndrome and Hypertension

CURRENT HYPERTENSION REPORTS. Article. 15(3):196-203.
[doi:10.1007/s11906-013-0337-4]
Ruiz-Hurtado G, Morel E, Domínguez-Rodríguez A, Llach A, Lezoualc'h F, Benitah JP, Gomez AM (2013).

Epac in cardiac calcium signaling

JOURNAL OF MOLECULAR AND CELLULAR CARDIOLOGY. Review. 58(SI):162-171.
[doi:10.1016/j.yjmcc.2012.11.021]
Solini A, Ruilope LM (2013).

How can resistant hypertension be identified and prevented?

NATURE REVIEWS CARDIOLOGY. Article. 10(5):293-296.
[doi:10.1038/nrcardio.2013.23]
Fontenla, Adolfo, Garcia-Donaire, Jose A., Hernandez, Felipe, Segura, Julian, Salgado, Ricardo, Cerezo, Cesar, Ruilope, Luis M., Arribas, Fernando (2013).

Management of Resistant Hypertension in a Multidisciplinary Unit of Renal Denervation: Protocol and Results

REVISTA ESPANOLA DE CARDIOLOGIA. Article. 66(5):364-370.
[doi:10.1016/j.rec.2012.09.006]
Schmieder, Roland E., Redon, Josep, Grassi, Guido, Kjeldsen, Sverre E., Mancia, Giuseppe, Narkiewicz, Krzysztof, Parati, Gianfranco, Ruilope, Luis, van de Borne, Philippe, Tsioufis, Costas (2013).

Updated ESH position paper on interventional therapy of resistant hypertension

EuroIntervention. Review. 9(R):58-66.
[doi:10.4244/EIJV9SRA11]
Ruilope LM, Pontremoli R (2013).

Serum uric acid and cardio-renal diseases

CURRENT MEDICAL RESEARCH AND OPINION. Review. 29(3):25-31.
[doi:10.1185/03007995.2013.790803]
Malmberg, Klas, Hanefeld, Markolf, Ruilope, Luis, Lincoff, A., Viberti, Giancarlo, Mudie, Nadejda, Urbanowska, Teresa, Reigner, Sylvie Meyer, Herz, Matthias (2013).

EFFECTS OF ALEGLITAZAR ON CARDIOVASCULAR RISK FACTORS IN PATIENTS WITH STAGE 3 CHRONIC KIDNEY DISEASE AND TYPE II DIABETES

JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY. Meeting Abstract. 61(10, S):1173-1173.
[doi:10.1016/S0735-1097(13)61173-0]
Caro J, Morales E, Gutierrez E, Ruilope LM, Praga M (2013).

Malignant Hypertension in Patients Treated With Vascular Endothelial Growth Factor Inhibitors

Journal of Clinical Hypertension. Article. 15(3):215-216.
[doi:10.1111/jch.12052]
Armario, Pedro, Oliveras, Anna, Hernandez-Del-Rey, Raquel, Suarez, Carmen, Martell, Nieves, Ruilope, Luis M., De La Sierra, Alejandro, Spanish Soc Hypertension (2013).

Increased pulse pressure is associated with left atrial enlargement in resistant hypertensive patients

BLOOD PRESSURE. Article. 22(1):39-44.
[doi:10.3109/08037051.2012.701789]
Segura De La Morena, Julian, Ruilope Urioste, Luis M. (2013).

What blood pressure levels have more influence in the development of target organ damage in patients with resistant hypertension?

MEDICINA CLINICA. Editorial Material. 140(1):20-21.
[doi:10.1016/j.medcli.2012.06.018]
Oliveras, Anna, Garcia-Ortiz, Luis, Segura, Julian, Banegas, Jose R., Martell-Claros, Nieves, Vigil, Luis, Suarez, Carmen, Gomez-Marcos, Manuel A., Abad-Cardiel, Maria, Vazquez, Susana, de la Cruz, Juan J., Franklin, Stanley S., Ruilope, Luis M., de la Sierra, Alejandro, PRESCEN Study (2013).

Association between urinary albumin excretion and both central and peripheral blood pressure in subjects with insulin resistance

JOURNAL OF HYPERTENSION. Article. 31(1):103-108.
[doi:10.1097/HJH.0b013e32835ac7b5]

2012

Torres VE, Chapman AB, Devuyst O, Gansevoort RT, Grantham JJ, Higashihara E, Perrone RD, Krasa HB, Ouyang J, Czerwiec FS (2012).

Tolvaptan in Patients with Autosomal Dominant Polycystic Kidney Disease

NEW ENGLAND JOURNAL OF MEDICINE. Article. 367(25):2407-2418.
[doi:10.1056/NEJMoa1205511]
Parving HH, Brenner BM, McMurray JJ, de Zeeuw D, Haffner SM, Solomon SD, Chaturvedi N, Persson F, Desai AS, Nicolaides M, Richard A, Xiang Z, Brunel P, Pfeffer MA (2012).

Cardiorenal End Points in a Trial of Aliskiren for Type 2 Diabetes

NEW ENGLAND JOURNAL OF MEDICINE. Article. 367(23):2204-2213.
[doi:10.1056/NEJMoa1208799]
Zannad F, Dallongeville J, Macfadyen RJ, Ruilope LM, Wilhelmsen L, De Backer G, Graham I, Lorenz M, Mancia G, Morrow DA, Reiner Z, Koenig W (2012).

Prevention of cardiovascular disease guided by total risk estimations - challenges and opportunities for practical implementation: highlights of a CardioVascular Clinical Trialists (CVCT) Workshop of the ESC Working Group on CardioVascular Pharmacology and Drug Therapy

European Journal of Preventive Cardiology. Review. 19(6):1454-1464.
[doi:10.1177/1741826711424873]
Ruilope, L. M., Schumacher, Helmut (2012).

Telmisartan 80 mg/hydrochlorothiazide 25 mg single-pill combination in the treatment of hypertension

EXPERT OPINION ON PHARMACOTHERAPY. Editorial Material. 13(16):2417-2425.
[doi:10.1517/14656566.2012.733698]
Zannad, Faiez, Stough, Wendy Gattis, Rossignol, Patrick, Bauersachs, Johann, McMurray, John J. V., Swedberg, Karl, Struthers, Allan D., Voors, Adriaan A., Ruilope, Luis M., Bakris, George L., O'Connor, Christopher M., Gheorghiade, Mihai, Mentz, Robert J., Cohen-Solal, Alain, Maggioni, Aldo P., Beygui, Farzin, Filippatos, Gerasimos S., Massy, Ziad A., Pathak, Atul, Pina, Ileana L., Sabbah, Hani N., Sica, Domenic A., Tavazzi, Luigi, Pitt, Bertram (2012).

Mineralocorticoid receptor antagonists for heart failure with reduced ejection fraction: integrating evidence into clinical practice

EUROPEAN HEART JOURNAL. Review. 33(22):2782-18.
[doi:10.1093/eurheartj/ehs257]
Ruilope, Luis M., Schmieder, Roland (2012).

Current status of renal denervation in resistant hypertension

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION. Review. 6(6):414-416.
[doi:10.1016/j.jash.2012.10.001]
Banegas, Jose R., Graciani, Auxiliadora, de la Cruz-Troca, Juan J., Leon-Munoz, Luz M., Guallar-Castillon, Pilar, Coca, Antonio, Ruilope, Luis M., Rodriguez-Artalejo, Fernando (2012).

Achievement of Cardiometabolic Goals in Aware Hypertensive Patients in Spain A Nationwide Population-Based Study

HYPERTENSION. Article. 60(4):898-905.
[doi:10.1161/HYPERTENSIONAHA.112.193078]
Ruiz-Hurtado, Gema, Gomez-Hurtado, Nieves, Fernandez-Velasco, Maria, Calderon, Eva, Smani, Tarik, Ordonez, Antonio, Cachofeiro, Victoria, Bosca, Lisardo, Diez, Javier, Gomez, Ana Maria, Delgado, Carmen (2012).

Cardiotrophin-1 induces sarcoplasmic reticulum Ca-2 leak and arrhythmogenesis in adult rat ventricular myocytes

CARDIOVASCULAR RESEARCH. Article. 96(1):81-89.
[doi:10.1093/cvr/cvs234]
Mentz, Robert J., Kaski, Juan-Carlos, Dan, Gheorghe-Andrei, Goldstein, Sidney, Stockbridge, Norman, Alonso-Garcia, Angeles, Ruilope, Luis M., Martinez, Felipe A., Zannad, Faiez, Pitt, Bertram, Fiuzat, Mona, O'Connor, Christopher M. (2012).

Implications of geographical variation on clinical outcomes of cardiovascular trials

AMERICAN HEART JOURNAL. Article. 164(3):303-312.
[doi:10.1016/j.ahj.2012.06.006]
Ruilope, Luis M. (2012).

Untitled

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM. Editorial Material. 13(3):408-408.
[doi:10.1177/1470320312453243]
de Boer, Rudolf A., Azizi, Michel, Danser, A. H. Jan, Nguyen, Genevieve, Nussberger, Juerg, Ruilope, Luis M., Schmieder, Roland E., Volpe, Massimo (2012).

Dual RAAS suppression: recent developments and implications in light of the ALTITUDE study

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM. Editorial Material. 13(3):409-412.
[doi:10.1177/1470320312455271]
Segura, Julian, Ruilope, Luis M. (2012).

Are there new threshold and goals in the treatment of arterial hypertension?

EUROPEAN JOURNAL OF CLINICAL INVESTIGATION. Review. 42(8):914-920.
[doi:10.1111/j.1365-2362.2012.02658.x]
Zhu, Dingliang L., Bays, Harold, Gao, Pingjin, Mattheus, Michaela, Voelker, Birgit, Ruilope, Luis M. (2012).

Efficacy and Tolerability of Initial Therapy With Single-Pill Combination Telmisartan/Hydrochlorothiazide 80/25 mg in Patients With Grade 2 or 3 Hypertension: A Multinational, Randomized, Double-Blind, Active-Controlled Trial

CLINICAL THERAPEUTICS. Article. 34(7):1613-1624.
[doi:10.1016/j.clinthera.2012.05.007]
Catalina Romero, Carlos, Cortes Arcas, Maria Victoria, Calvo Bonacho, Eva, Ruilope Urioste, Luis Miguel (2012).

Overweight and obesity among physicians in Spain; results from the ICARIA Study

MEDICINA CLINICA. Letter. 139(2):84-85.
[doi:10.1016/j.medcli.2011.10.019]
de la Sierra, Alejandro, Banegas, Jose R., Oliveras, Anna, Gorostidi, Manuel, Segura, Julian, de la Cruz, Juan J., Armario, Pedro, Ruilope, Luis M. (2012).

Clinical differences between resistant hypertensives and patients treated and controlled with three or less drugs

JOURNAL OF HYPERTENSION. Article. 30(6):1211-1216.
[doi:10.1097/HJH.0b013e328353634e]
Antonio Garcia-Donaire, Jose, Dalfo Baque, Antoni, Sanclemente Anso, Carmen, Urdiales Castillo, Daniel, Martinez Deben, Francisco, Ortega Lopez, Nicolas, Pizarro Nunez, Juan Luis, Martin Oterino, Jose Angel, Garcia-Norro Herreros, Javier, Mediavilla Garcia, Juan Diego, Vara Gonzalez, Luis Alberto, Prieto Diaz, Miguel Angel, Vila Coll, Maria Antonia, Gomez Fernandez, Pablo, Rossique Delmas, Pilar, Gascon Becerril, Ramon, Perez Alvarez, Roberto, Delgado Zamora, Rodrigo, de Vega Santos, Tomas, Cerezo Olmos, Cesar, Segura de La Morena, Julian, Ruilope, Luis M. (2012).

Measurement of blood pressure in consultation and automated mesurement (BPTru (R)) to evaluate the white coat effect

MEDICINA CLINICA. Article. 138(14):597-601.
[doi:10.1016/j.medcli.2011.10.030]
Ruilope, Luis M. (2012).

Current challenges in the clinical management of hypertension

NATURE REVIEWS CARDIOLOGY. Review. 9(5):267-275.
[doi:10.1038/nrcardio.2011.157]
Schmieder, Roland E., Redon, Josep, Grassi, Guido, Kjeldsen, Sverre E., Mancia, Giuseppe, Narkiewicz, Krzysztof, Parati, Gianfranco, Ruilope, Luis, van de Borne, Philippe, Tsioufis, Costas (2012).

ESH Position Paper: Renal denervation - an interventional therapy of resistant hypertension

JOURNAL OF HYPERTENSION. Article. 30(5):837-841.
[doi:10.1097/HJH.0b013e328352ce78]
Zannad, Faiez, De Backer, Guy, Graham, Ian, Lorenz, Matthias, Mancia, Giuseppe, Morrow, David A., Reiner, Zeljko, Koenig, Wolfgang, Dallongeville, Jean, Macfadyen, Robert J., Ruilope, Luis M., Wilhelmsen, Lars, ESC Working Grp CardioVasc Pharmac (2012).

Risk stratification in cardiovascular disease primary prevention - scoring systems, novel markers, and imaging techniques

FUNDAMENTAL & CLINICAL PHARMACOLOGY. Review. 26(2):163-174.
[doi:10.1111/j.1472-8206.2011.01023.x]
Ruilope, Luis M. (2012).

DIABETES Glycemic and blood-pressure control-lower is not better

NATURE REVIEWS NEPHROLOGY. News Item. 8(4):199-200.
[doi:10.1038/nrneph.2012.34]
Volpe, Massimo, Danser, A. H. Jan, Menard, Joel, Waeber, Bernard, Mueller, Dominik N., Maggioni, Aldo P., Ruilope, Luis M. (2012).

Inhibition of the renin-angiotensin-aldosterone system: is there room for dual blockade in the cardiorenal continuum?

JOURNAL OF HYPERTENSION. Review. 30(4):647-654.
[doi:10.1097/HJH.0b013e32834f6e00]
de la Sierra, Alejandro, Banegas, Jose R., Segura, Julian, Gorostidi, Manuel, Ruilope, Luis M., CARDIORISC Event Investigators (2012).

Ambulatory blood pressure monitoring and development of cardiovascular events in high-risk patients included in the Spanish ABPM registry: the CARDIORISC Event study

JOURNAL OF HYPERTENSION. Article. 30(4):713-719.
[doi:10.1097/HJH.0b013e328350bb40]
Menne, Jan, Izzo, Jr., Joseph L., Ito, Sadayoshi, Januszewicz, Andrzej, Katayama, Shigehiro, Chatzykirkou, Christos, Mimran, Albert, Rabelink, Ton J., Ritz, Eberhard, Ruilope, Luis M., Rump, Lars C., Viberti, Giancarlo, Haller, Hermann, ROADMAP Investigators (2012).

Prevention of microalbuminuria in patients with type 2 diabetes and hypertension

JOURNAL OF HYPERTENSION. Article. 30(4):811-818.
[doi:10.1097/HJH.0b013e328351856d]
Sarafidis, Pantelis A., Ruilope, Luis M. (2012).

Cardiorenal disease development under chronic renin-angiotensin-aldosterone system suppression

JOURNAL OF THE RENIN-ANGIOTENSIN-ALDOSTERONE SYSTEM. Editorial Material. 13(1):217-219.
[doi:10.1177/1470320312439140]
Ruilope, Luis M. (2012).

Antihypertensives in people with gout or asymptomatic hyperuricaemia

BRITISH MEDICAL JOURNAL. Editorial Material. 344(d7961).
[doi:10.1136/bmj.d7961]
Domínguez-Rodríguez A, Ruiz-Hurtado G, Benitah JP, Gómez AM (2012).

The other side of cardiac Ca2+ signaling: transcriptional control

Frontiers in Physiology. Review. 3:452-452.
[doi:10.3389/fphys.2012.00452]
Cerezo, Cesar, Ruilope, Luis M., Segura, Julian, Garcia-Donaire, Jose A., de la Cruz, Juan J., Banegas, Jose R., Waeber, Bernard, Rabelink, Ton J., Messerli, Franz H. (2012).

Microalbuminuria breakthrough under chronic renin-angiotensin-aldosterone system suppression

JOURNAL OF HYPERTENSION. Article. 30(1):204-209.
[doi:10.1097/HJH.0b013e32834d9e0f]

2011

Garcia-Donaire, J. A., Segura, J., Cerezo, C., Ruilope, L. M. (2011).

A review of renal, cardiovascular and mortality endpoints in antihypertensive trials in diabetic patients

BLOOD PRESSURE. Review. 20(6):322-334.
[doi:10.3109/08037051.2011.602878]
Januszewicz, A., Ritz, E., Viberti, G., Mimran, A., Rabelink, A. J., Rump, L. C., Ruilope, L. M., Katayama, S., Ito, S., Izzo, Jr., J. L., Haller, H. (2011).

Office and ambulatory pulse pressure-association with clinical characteristics and cardiovascular risk factors in normoalbuminuric patients with type 2 diabetes (ROADMAP study)

JOURNAL OF HUMAN HYPERTENSION. Article. 25(11):679-685.
[doi:10.1038/jhh.2010.111]
Segura, Julian, Cerezo, Cesar, Garcia-Donaire, Jose A., Schmieder, Roland E., Praga, Manuel, de la Sierra, Alejandro, Ruilope, Luis M. (2011).

Validation of a therapeutic scheme for the treatment of resistant hypertension

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION. Article. 5(6):498-504.
[doi:10.1016/j.jash.2011.08.003]
Gorostidi, Manuel, de la Sierra, Alejandro, Gonzalez-Albarran, Olga, Segura, Julian, de la Cruz, Juan J., Vinyoles, Ernest, Llisterri, Jose L., Aranda, Pedro, Ruilope, Luis M., Banegas, Jose R., Spanish Soc Hypertension ABPM Regi (2011).

Abnormalities in ambulatory blood pressure monitoring in hypertensive patients with diabetes

HYPERTENSION RESEARCH. Article. 34(11):1185-1189.
[doi:10.1038/hr.2011.100]
Tendera, Michal, Aboyans, Victor, Bartelink, Marie-Louise, Baumgartner, Iris, Clement, Denis, Collet, Jean-Philippe, Cremonesi, Alberto, De Carlo, Marco, Erbel, Raimund, Fowkes, F. Gerry R., Heras, Magda, Kownator, Serge, Minar, Erich, Ostergren, Jan, Poldermans, Don, Riambau, Vincent, Roffi, Marco, Roether, Joachim, Sievert, Horst, van Sambeek, Marc, Zeller, Thomas, Bax, Jeroen, Auricchio, Angelo, Baumgartner, Helmut, Ceconi, Claudio, Dean, Veronica, Deaton, Christi, Fagard, Robert, Funck-Brentano, Christian, Hasdai, David, Hoes, Arno, Knuuti, Juhani, Kolh, Philippe, McDonagh, Theresa, Moulin, Cyril, Poldermans, Don, Popescu, Bogdan, Reiner, Zeljko, Sechtem, Udo, Sirnes, Per Anton, Torbicki, Adam, Vahanian, Alec, Windecker, Stephan, ESC Comm Practice Guidelines (2011).

ESC Guidelines on the diagnosis and treatment of peripheral artery diseases Document covering atherosclerotic disease of extracranial carotid and vertebral, mesenteric, renal, upper and lower extremity arteries The Task Force on the Diagnosis and Treatment of Peripheral Artery Diseases of the European Society of Cardiology (ESC)

EUROPEAN HEART JOURNAL. Article. 32(22):2851-2906.
[doi:10.1093/eurheartj/ehr211]
Armario, Pedro, Oliveras, Anna, Hernandez Del Rey, Raquel, Miguel Ruilope, Luis, De la Sierra, Alejandro, SEH-LELHA (2011).

Prevalence of target organ damage and metabolic abnormalities in resistant hypertension

MEDICINA CLINICA. Article. 137(10):435-439.
[doi:10.1016/j.medcli.2011.02.035]
Ruilope, Luis M. (2011).

Normotension, blood pressure variability and early target organ damage

HYPERTENSION RESEARCH. Editorial Material. 34(10):1075-1075.
[doi:10.1038/hr.2011.122]
Schmieder, Roland E., Ruilope, Luis-Miguel, Barnett, Anthony H. (2011).

Renal protection with angiotensin receptor blockers: where do we stand?

JOURNAL OF NEPHROLOGY. Review. 24(5):569-580.
[doi:10.5301/JN.2011.6445]
Ruilope, Luis M., Schaefer, Angie (2011).

Efficacy of Sevikar (R) compared to the combination of perindopril plus amlodipine on central arterial blood pressure in patients with moderate-to-severe hypertension: Rationale and design of the SEVITENSION study

Contemporary Clinical Trials. Article. 32(5):710-716.
[doi:10.1016/j.cct.2011.04.011]
Ruilope, Luis M. (2011).

Telmisartan for the management of patients at high cardiovascular risk

CURRENT MEDICAL RESEARCH AND OPINION. Review. 27(8):1673-1682.
[doi:10.1185/03007995.2011.597378]
Ruilope, Luis M., Bakris, George L. (2011).

Renal function and target organ damage in hypertension

EUROPEAN HEART JOURNAL. Review. 32(13):1599-1604.
[doi:10.1093/eurheartj/ehr003]
Ruilope, Luis M., Solini, Anna (2011).

RAS Blockade for Every Diabetic Patient: Pro and Con

DIABETES CARE. Article. 34(2):320-324.
[doi:10.2337/dc11-s248]
de la Sierra, Alejandro, Segura, Julian, Banegas, Jose R., Gorostidi, Manuel, de la Cruz, Juan J., Armario, Pedro, Oliveras, Anna, Ruilope, Luis M. (2011).

Clinical Features of 8295 Patients With Resistant Hypertension Classified on the Basis of Ambulatory Blood Pressure Monitoring

HYPERTENSION. Article. 57(5):898-74.
[doi:10.1161/HYPERTENSIONAHA.110.168948]
Parthasarathy, Hari K., Menard, Joel, White, William B., Young, Jr., William F., Williams, Gordon H., Williams, Bryan, Miguel Ruilope, Luis, McInnes, Gordon T., Connell, John M., MacDonald, Thomas M. (2011).

A double-blind, randomized study comparing the antihypertensive effect of eplerenone and spironolactone in patients with hypertension and evidence of primary aldosteronism

JOURNAL OF HYPERTENSION. Article. 29(5):980-990.
[doi:10.1097/HJH.0b013e3283455ca5]
Abellan Aleman, Jose, Ruilope Urioste, Luis Miguel, Leal Hernandez, Mariano, Armario Garcia, Pedro, Tiberio Lopez, Gregorio, Martell Claros, Nieves (2011).

Control of cardiovascular risk factors in patients with stroke attended in primary care in Spain. ICTUSCARE study

MEDICINA CLINICA. Article. 136(8):329-335.
[doi:10.1016/j.medcli.2010.04.035]
Haller, Hermann, Ito, Sadayoshi, Izzo, Jr., Joseph L., Januszewicz, Andrzej, Katayama, Shigehiro, Menne, Jan, Mimran, Albert, Rabelink, Ton J., Ritz, Eberhard, Ruilope, Luis M., Rump, Lars C., Viberti, Giancarlo, ROADMAP Trial Investigators (2011).

Olmesartan for the Delay or Prevention of Microalbuminuria in Type 2 Diabetes

NEW ENGLAND JOURNAL OF MEDICINE. Article. 364(10):907-917.
[doi:10.1056/NEJMoa1007994]
Oliveras, Anna, Armario, Pedro, Martell-Claros, Nieves, Ruilope, Luis M., de la Sierra, Alejandro, Spanish Soc Hypertension Resistant (2011).

Urinary Albumin Excretion Is Associated With Nocturnal Systolic Blood Pressure in Resistant Hypertensives

HYPERTENSION. Article. 57(3):556-373.
[doi:10.1161/HYPERTENSIONAHA.110.165563]
Mancia, Giuseppe, Parati, Gianfranco, Bilo, Grzegorz, Choi, Jasmine, Kilama, Michael Ochan, Ruilope, Luis M., TALENT Investigators (2011).

Blood pressure control by the nifedipine GITS-telmisartan combination in patients at high cardiovascular risk: the TALENT study

JOURNAL OF HYPERTENSION. Article. 29(3):600-609.
[doi:10.1097/HJH.0b013e328342ef04]
Segura, Julian, Ruilope, Luis M. (2011).

Dual-Acting Angiotensin Receptor-Neprilysin Inhibition

CURRENT HYPERTENSION REPORTS. Article. 13(1):74-78.
[doi:10.1007/s11906-010-0166-7]
Ruilope, Luis M. (2011).

Blood pressure and the kidney

NATURE REVIEWS NEPHROLOGY. Editorial Material. 7(2):73-74.
[doi:10.1038/nrneph.2010.189]
Segura, Julian, Ruilope, Luis M. (2011).

Hypertension in Moderate-to-Severe Nondiabetic CKD Patients

ADVANCES IN CHRONIC KIDNEY DISEASE. Article. 18(1):23-27.
[doi:10.1053/j.ackd.2010.11.001]
Volpe, Massimo, Azizi, Michel, Danser, A. H. Jan, Nguyen, Genevieve, Ruilope, Luis M. (2011).

Twisting arms to angiotensin receptor blockers/antagonists: the turn of cancer

EUROPEAN HEART JOURNAL. Editorial Material. 32(1):19-19.
[doi:10.1093/eurheartj/ehq382]

2010

Esler, Murray D., Krum, Henry, Sobotka, Paul A., Schlaich, Markus P., Schmieder, Roland E., Boehm, Michael, Mahfoud, Felix, Sievert, Horst, Wunderlich, Nina, Rump, Lars Christian, Vonend, Oliver, Uder, Michael, Lobo, Mel, Caulfield, Mark, Erglis, Andrejs, Azizi, Michel, Sapoval, Marc, Thambar, Suku, Persu, Alexandre, Renkin, Jean, Schunkert, Heribert, Weil, Joachim, Hoppe, Uta C., Walton, Tony, Scheinert, Dierk, Binder, Thomas, Januszewicz, Andrzej, Witkowski, Adam, Ruilope, Luis M., Whitbourn, Robert, Bruck, Heike, Downes, Mark, Luescher, Thomas F., Jardine, Alan G., Webster, Mark W., Zeller, Thomas, Sadowski, Jerzy, Bartus, Krzysztof, Straley, Craig A., Barman, Neil C., Lee, David P., Witteles, Ronald M., Bhalla, Vivek, Massaro, Joseph M., Symplicity HTN-2 Investigators (2010).

Renal sympathetic denervation in patients with treatment-resistant hypertension (The Symplicity HTN-2 Trial): a randomised controlled trial

LANCET. Article. 376(9756):1903-1909.
[doi:10.1016/S0140-6736(10)62039-9]
Vinyoles, Ernest, Rodriguez-Blanco, Teresa, de la Sierra, Alejandro, Felip, Angela, Banegas, Jose R., de la Cruz, Juan J., Gorostidi, Manuel, Sobrino, Javier, Segura, Julian, Roca-Cusachs, Alex, Ruilope, Luis M., Spanish Soc Hypertension ABPM Regi (2010).

Isolated clinic hypertension: diagnostic criteria based on 24-h blood pressure definition

JOURNAL OF HYPERTENSION. Article. 28(12):2407-2413.
[doi:10.1097/HJH.0b013e32833f381d]
Parati, G., Stergiou, G. S., Asmar, R., Bilo, G., de Leeuw, P., Imai, Y., Kario, K., Lurbe, E., Manolis, A., Mengden, T., O'Brien, E., Ohkubo, T., Padfield, P., Palatini, P., Pickering, T. G., Redon, J., Revera, M., Ruilope, L. M., Shennan, A., Staessen, J. A., Tisler, A., Waeber, B., Zanchetti, A., Mancia, G., ESH Working Grp Blood Pressure Mon (2010).

European Society of Hypertension practice guidelines for home blood pressure monitoring.

JOURNAL OF HUMAN HYPERTENSION. Review. 24(12):779-785.
[doi:10.1038/jhh.2010.54]
Banegas, J. R., de la Sierra, A., Segura, J., Ruilope, L. M. (2010).

Office vs. ambulatory control of hypertension in CHD patients: response to the letter "When office blood pressure measurement is not enough" by Barrios and colleagues.

International Journal of Cardiology. Letter. 145(2):352-352.
[doi:10.1016/j.ijcard.2009.09.568]
Ruilope, Luis M., Segura, Julian (2010).

ARBs and ACEis together in the treatment of hypertension and its complications? current practical recommendations.

EXPERT OPINION ON PHARMACOTHERAPY. Review. 11(16):2619-2623.
[doi:10.1517/14656566.2010.522992]
Gonzalez, Roberto, Morales, Enrique, Segura, Julian, Ruilope, Luis M., Praga, Manuel (2010).

Long-term renal survival in malignant hypertension

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 25(10):3266-3272.
[doi:10.1093/ndt/gfq143]
Segura, Julian, de la Sierra, Alejandro, Ruilope, Luis M. (2010).

Detection and Treatment of Resistant Hypertension

CURRENT HYPERTENSION REPORTS. Article. 12(5):325-330.
[doi:10.1007/s11906-010-0136-0]
James, W. Philip T., Caterson, Ian D., Coutinho, Walmir, Finer, Nick, Van Gaal, Luc F., Maggioni, Aldo P., Torp-Pedersen, Christian, Sharma, Arya M., Shepherd, Gillian M., Rode, Richard A., Renz, Cheryl L., SCOUT Investigators (2010).

Effect of Sibutramine on Cardiovascular Outcomes in Overweight and Obese Subjects

NEW ENGLAND JOURNAL OF MEDICINE. Article. 363(10):905-917.
[doi:10.1056/NEJMoa1003114]
de la Sierra, Alejandro, Segura, Julian, Gorostidi, Manuel, Banegas, Jose R., de la Cruz, Juan J., Ruilope, Luis M. (2010).

Diurnal blood pressure variation, risk categories and antihypertensive treatment.

HYPERTENSION RESEARCH. Review. 33(8):767-771.
[doi:10.1038/hr.2010.111]
Gustafsson, Finn, Segura, Julian, Ruilope, Luis M. (2010).

How should we manage heart failure developing in patients already treated with angiotensin-converting enzyme inhibitors and beta-blockers for hypertension, diabetes or coronary disease?

JOURNAL OF HYPERTENSION. Review. 28(8):1595-1598.
[doi:10.1097/HJH.0b013e32833984b8]
Garcia-Donaire, Jose A., Ruilope, Luis M. (2010).

Systolic Pressure, Diastolic Pressure, or Pulse Pressure as a Cardiovascular Risk Factor in Renal Disease

CURRENT HYPERTENSION REPORTS. Article. 12(4):307-312.
[doi:10.1007/s11906-010-0129-z]
Morganti, Alberto, European Study Grp Validation DiaS, Ruilope Urioste, Luis Miguel (2010).

A comparative study on inter and intralaboratory reproducibility of renin measurement with a conventional enzymatic method and a new chemiluminescent assay of immunoreactive renin

JOURNAL OF HYPERTENSION. Article. 28(6):1307-1312.
[doi:10.1097/HJH.0b013e32833857ad]
Ruilope, Luis, Izzo, Joseph, Haller, Hermann, Waeber, Bernard, Oparil, Suzanne, Weber, Michael, Bakris, George, Sowers, James (2010).

Prevention of Microalbuminuria in Patients With Type 2 Diabetes: What Do We Know?

Journal of Clinical Hypertension. Review. 12(6):422-430.
[doi:10.1111/j.1751-7176.2010.00289.x]
Segura de La Morena, Julian, Garcia Donaire, Jose Antonio, Ruilope Urioste, Luis Miguel (2010).

New therapeutic strategies to improve control of arterial hypertension and simplify the regimen of drug treatment

MEDICINA CLINICA. Review. 134(14):635-642.
[doi:10.1016/j.medcli.2010.01.020]
Banegas, Jose R., de la Sierra, Alex, Aranda, Pedro, Ruilope, Luis M. (2010).

Clinical overdoing of consensus conference about hypertension Reply

MEDICINA CLINICA. Letter. 134(11):516-517.
[doi:10.1016/j.medcli.2009.07.041]
Miguel Ruilope, Luis, Dukat, Andrej, Boehm, Michael, Lacourciere, Yves, Gong, Jianjian, Lefkowitz, Martin P. (2010).

Blood-pressure reduction with LCZ696, a novel dual-acting inhibitor of the angiotensin II receptor and neprilysin: a randomised, double-blind, placebo-controlled, active comparator study

LANCET. Article. 375(9722):1255-1266.
[doi:10.1016/S0140-6736(09)61966-8]
Mann, Johannes F. E., Green, Damian, Jamerson, Kenneth, Ruilope, Luis M., Kuranoff, Susan J., Littke, Thomas, Viberti, Giancarlo, ASCEND Study Grp (2010).

Avosentan for Overt Diabetic Nephropathy

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Article. 21(3):527-535.
[doi:10.1681/ASN.2009060593]
Ruilope, Luis M. (2010).

The Framingham risk score is valuable in Europeans.

NATURE REVIEWS NEPHROLOGY. News Item. 6(1):14-15.
[doi:10.1038/nrneph.2009.205]

de la Sierra A, Banegas JR, Bursztyn M, Parati G, Stergiou G, Mateu A, Vinyoles E, Segura J, Gorostidi M, Ruilope LM ().

Prognostic Relevance of Short-Term Blood Pressure Variability: The Spanish ABPM Registry.

HYPERTENSION. Article.
[doi:10.1161/HYPERTENSIONAHA.119.14508]
Tamargo J, Ruilope LM ().

Investigational calcium channel blockers for the treatment of hypertension.

EXPERT OPINION ON INVESTIGATIONAL DRUGS. Article.
[doi:10.1080/13543784.2016.1241764]
Gijon-Conde T, Gorostidi M, Camafort M, Abad-Cardiel M, Martin-Rioboo E, Morales-Olivas F, Vinyoles E, Armario P, Banegas JR, Coca A, de la Sierra A, Martell-Claros N, Redon J, Ruilope LM, Segura J ().

Documento de la Sociedad Española de Hipertensión-Liga Española para la Lucha contra la Hipertensión Arterial (SEH-LELHA) sobre las guías ACC/AHA 2017 de hipertensión arterial.

Hipertension y Riesgo Vascular. Abstract of Published Item.
[doi:10.1016/j.hipert.2018.04.001]
Banegas JR, Ruilope LM ().

Estudio de mortalidad del Registro español de monitorización ambulatoria de la presión arterial. Una llamada a la traslación de la monitorización ambulatoria de la presión arterial a la práctica clínica.

Hipertension y Riesgo Vascular. Article.
[doi:10.1016/j.hipert.2018.05.002]
de la Sierra A, Banegas JR, Divisón JA, Gorostidi M, Vinyoles E, de la Cruz JJ, Segura J, Ruilope LM ().

Ambulatory blood pressure in hypertensive patients with inclusion criteria for the SPRINT trial.

JOURNAL OF THE AMERICAN SOCIETY OF HYPERTENSION. Article.
[doi:10.1016/j.jash.2016.10.013]
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