Publications
2021
Castro-Vazquez, D, Lamana, A, Arribas-Castano, P, Gutierrez-Canas, I, Villanueva-Romero, R, Perez-Garcia, S, Martinez, C, Juarranz, Y, de Cordoba, SF, Gonzalez-alvaro, I, Gomariz, RP, Carrion, M (2021).
The Neuropeptide VIP Limits Human Osteoclastogenesis: Clinical Associations with Bone Metabolism Markers in Patients with Early Arthritis
Biomedicines. Article. 9(12).
[doi:10.3390/biomedicines9121880]
Fernandez-Perez R, Lopez-Santalla M, Sánchez-Domínguez R, Alberquilla O, Gutiérrez-Cañas I, Juarranz Y, Bueren JA, Garin MI (2021).
Enhanced Susceptibility of Galectin-1 Deficient Mice to Experimental Colitis.
Frontiers in immunology. Article. 12:687443-687443.
[doi:10.3389/fimmu.2021.687443]
Perez-Garcia, S, Calamia, V, Hermida-Gomez, T, Gutierrez-Canas, I, Carrion, M, Villanueva-Romero, R, Castro, D, Martinez, C, Juarranz, Y, Blanco, FJ, Gomariz, RP (2021).
Proteomic Analysis of Synovial Fibroblasts and Articular Chondrocytes Co-Cultures Reveals Valuable VIP-Modulated Inflammatory and Degradative Proteins in Osteoarthritis
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 22(12).
[doi:10.3390/ijms22126441]
2020
Villanueva-Romero, R, Lamana, A, Flores-Santamaria, M, Carrion, M, Perez-Garcia, S, Triguero-Martinez, A, Tomero, E, Criado, G, Pablos, JL, Gonzalez-Alvaro, I, Martinez, C, Juarranz, Y, Gomariz, RP, Gutierrez-Canas, I (2020).
Comparative Study of Senescent Th Biomarkers in Healthy Donors and Early Arthritis Patients. Analysis of VPAC Receptors and Their Influence.
Cells. Article. 9(12).
[doi:10.3390/cells9122592]
Couvineau A, Gomariz RP, Tan YV (2020).
Editorial: GPCR in Inflammatory and Cancer Diseases.
Frontiers in Endocrinology. Editorial Material. 11:588157-588157.
[doi:10.3389/fendo.2020.588157]
Carrión M, Ramos-Leví AM, Seoane IV, Martínez-Hernández R, Serrano-Somavilla A, Castro D, Juarranz Y, González-Álvaro I, Gomariz RP, Marazuela M (2020).
Vasoactive intestinal peptide axis is dysfunctional in patients with Graves' disease.
SCIENTIFIC REPORTS. Article. 10(1):13018-13018.
[doi:10.1038/s41598-020-70138-3]
D'Agostino, G, Garcia-Cuesta, EM, Gomariz, RP, Rodriguez-Frade, JM, Mellado, M (2020).
The multilayered complexity of the chemokine receptor system.
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. Article. 528(2):347-358.
[doi:10.1016/j.bbrc.2020.02.120]
Lamana A, Villares R, Seoane IV, Andrés N, Lucas P, Emery P, Vital EM, Triguero-Martínez A, Marquez A, Ortiz AM, Maxime R, Martínez C, Martín J, Gomariz RP, Ponchel F, González-Álvaro I, Mellado M (2020).
Identification of a Human SOCS1 Polymorphism That Predicts Rheumatoid Arthritis Severity.
Frontiers in immunology. Article. 11:1336-1336.
[doi:10.3389/fimmu.2020.01336]
Martinez, C, Juarranz, Y, Gutierrez-Canas, I, Carrion, M, Perez-Garcia, S, Villanueva-Romero, R, Castro, D, Lamana, A, Mellado, M, Gonzalez-Alvaro, I, Gomariz, RP (2020).
A Clinical Approach for the Use of VIP Axis in Inflammatory and Autoimmune Diseases
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 21(1).
[doi:10.3390/ijms21010065]
Perez-Garcia, S, Carrion, M, Gutierrez-Canas, I, Villanueva-Romero, R, Castro, D, Martinez, C, Gonzalez-Alvaro, I, Blanco, FJ, Juarranz, Y, Gomariz, RP (2020).
Profile of Matrix-Remodeling Proteinases in Osteoarthritis: Impact of Fibronectin
Cells. Review. 9(1).
[doi:10.3390/cells9010040]
2019
Gomariz, RP, Juarranz, Y, Carrion, M, Perez-Garcia, S, Villanueva-Romero, R, Gonzalez-Alvaro, I, Gutierrez-Canas, I, Lamana, A, Martinez, C (2019).
An Overview of VPAC Receptors in Rheumatoid Arthritis: Biological Role and Clinical Significance
Frontiers in Endocrinology. Review. 10:729-729.
[doi:10.3389/fendo.2019.00729]
Carrion, M, Frommer, KW, Perez-Garcia, S, Muller-Ladner, U, Gomariz, RP, Neumann, E (2019).
The Adipokine Network in Rheumatic Joint Diseases
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 20(17).
[doi:10.3390/ijms20174091]
García-Cuesta EM, Santiago CA, Vallejo-Díaz J, Juarranz Y, Rodríguez-Frade JM, Mellado M (2019).
The Role of the CXCL12/CXCR4/ACKR3 Axis in Autoimmune Diseases.
Frontiers in Endocrinology. Review. 10:585-585.
[doi:10.3389/fendo.2019.00585]
Perez-Garcia, S, Carrion, M, Villanueva-Romero, R, Hermida-Gomez, T, Fernandez-Moreno, M, Mellado, M, Blanco, FJ, Juarranz, Y, Gomariz, RP (2019).
Wnt and RUNX2 mediate cartilage breakdown by osteoarthritis synovial fibroblast-derived ADAMTS-7 and-12
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. Article. 23(6):3974-3983.
[doi:10.1111/jcmm.14283]
Villanueva-Romero, R, Gutierrez-Canas, I, Carrion, M, Gonzalez-Alvaro, I, Rodriguez-Frade, JM, Mellado, M, Martinez, C, Gomariz, RP, Juarranz, Y (2019).
Activation of Th lymphocytes alters pattern expression and cellular location of VIP receptors in healthy donors and early arthritis patients.
SCIENTIFIC REPORTS. Article. 9(1):7383-7383.
[doi:10.1038/s41598-019-43717-2]
2018
Villares, R, Criado, G, Juarranz, Y, Lopez-Santalla, M, Garcia-Cuesta, EM, Rodriguez-Frade, JM, Leceta, J, Lucas, P, Pablos, JL, Martinez, C, Garin, MI, Gomariz, RP, Mellado, M (2018).
Inhibitory Role of Growth Hormone in the Induction and Progression Phases of Collagen-Induced Arthritis
Frontiers in immunology. Article. 9:1165-1165.
[doi:10.3389/fimmu.2018.01165]
Seoane, IV, Martinez, C, Garcia-Vicuna, R, Ortiz, AM, Juarranz, Y, Talayero, VC, Gonzalez-Alvaro, I, Gomariz, RP, Lamana, A (2018).
Vasoactive intestinal peptide gene polymorphisms, associated with its serum levels, predict treatment requirements in early rheumatoid arthritis
SCIENTIFIC REPORTS. Article. 8(1):2035-2035.
[doi:10.1038/s41598-018-20400-6]
Villanueva-Romero, R, Gutierrez-Canas, I, Carrion, M, Perez-Garcia, S, Seoane, IV, Martinez, C, Gomariz, RP, Juarranz, Y (2018).
The Anti-Inflammatory Mediator, Vasoactive Intestinal Peptide, Modulates the Differentiation and Function of Th Subsets in Rheumatoid Arthritis
JOURNAL OF IMMUNOLOGY RESEARCH. Review. 2018:6043710-6043710.
[doi:10.1155/2018/6043710]
2017
Tío L, Orellana C, Pérez-García S, Piqueras L, Escudero P, Juarranz Y, Garcia-Giralt N, Montañés F, Farran A, Benito P, Gomariz RP, Sanz MJ, Monfort J (2017).
Effect of chondroitin sulphate on synovitis of knee osteoarthritic patients
MEDICINA CLINICA. Article. 149(1):9-16.
[doi:10.1016/j.medcli.2016.12.045]
2016
Carrión M, Pérez-García S, Martínez C, Juarranz Y, Estrada-Capetillo L, Puig-Kröger A, Gomariz RP, Gutiérrez-Cañas I (2016).
VIP impairs acquisition of the macrophage proinflammatory polarization profile
JOURNAL OF LEUKOCYTE BIOLOGY. Article. 100(6):1385-1393.
[doi:10.1189/jlb.3A0116-032RR]
Pérez-García S, Gutiérrez-Cañas I, Seoane IV, Fernández J, Mellado M, Leceta J, Tío L, Villanueva-Romero R, Juarranz Y, Gomariz RP (2016).
Healthy and Osteoarthritic Synovial Fibroblasts Produce a Disintegrin and Metalloproteinase with Thrombospondin Motifs 4, 5, 7, and 12 Induction by IL-1 beta and Fibronectin and Contribution to Cartilage Damage
AMERICAN JOURNAL OF PATHOLOGY. Article. 186(9):2449-2461.
[doi:10.1016/j.ajpath.2016.05.017]
Lugo, Juana Maria, Tafalla, Carolina, Gonzalez, Aitor, Abos, Beatriz, Leceta, Javier, Gomariz, Rosa P., Castro, Rosario, Gorgoglione, Bartolomeo, Secombes, Christopher, Velazquez, Janet, Carpio, Yamila, Estrada, Mario Pablo (2016).
Recent discoveries of pituitary adenylate cyclase activating peptide (PACAP) function in the teleost fish adaptative immunity
FISH & SHELLFISH IMMUNOLOGY. Meeting Abstract. 53(SI):87-88.
Perez-Garcia, Selene, Carrion, Mar, Gutierrez-Canas, Irene, Gonzalez-Alvaro, Isidoro, Gomariz, Rosa P., Juarranz, Yasmina (2016).
VIP and CRF reduce ADAMTS expression and function in osteoarthritis synovial fibroblasts
JOURNAL OF CELLULAR AND MOLECULAR MEDICINE. Article. 20(4):678-687.
[doi:10.1111/jcmm.12777]
Seoane, Iria V., Ortiz, Ana M., Piris, Lorena, Lamana, Amalia, Juarranz, Yasmina, Garcia-Vicuna, Rosario, Gonzalez-Alvaro, Isidoro, Gomariz, Rosa P., Martinez, Carmen (2016).
Clinical Relevance of VPAC1 Receptor Expression in Early Arthritis: Association with IL-6 and Disease Activity
PLOS ONE. Article. 11(2).
[doi:10.1371/journal.pone.0149141]
Miguel Rodriguez-Frade, Jose, Martinez-Munoz, Laura, Villares, Ricardo, Cascio, Graciela, Lucas, Pilar, Gomariz, Rosa P., Mellado, Mario (2016).
Chemokine Detection Using Receptors Immobilized on an SPR Sensor Surface
Methods in Enzymology. Review. 570:1-18.
[doi:10.1016/bs.mie.2015.09.013]
2015
Villares, Ricardo J., Criado, Gabriel, Gomariz, Rosa P., Juarranz, Yasmina, Leceta, Javier, Cascio, Graciela, Pablos, Jose L., Mellado, Mario (2015).
Protective and Therapeutic Effects of Growth Hormone on Collagen-Induced Arthritis
ARTHRITIS & RHEUMATOLOGY. Meeting Abstract. 67(10).
Jimeno, Rebeca, Leceta, Javier, Garin, Marina, Ortiz, Ana M., Mellado, Mario, Miguel Rodriguez-Frade, Jose, Martinez, Carmen, Perez-Garcia, Selene, Gomariz, Rosa P., Juarranz, Yasmina (2015).
T(h)17 polarization of memory T-h cells in early arthritis: the vasoactive intestinal peptide effect
JOURNAL OF LEUKOCYTE BIOLOGY. Article. 98(2):257-269.
[doi:10.1189/jlb.3A0714-327R]
Seoane, Iria V., Tomero, Eva, Martinez, Carmen, Garcia-Vicuna, Rosario, Juarranz, Yasmina, Lamana, Amalia, Ocon, Elena, Ortiz, Ana M., Gomez-Leon, Nieves, Gonzalez-Alvaro, Isidoro, Gomariz, Rosa P. (2015).
Vasoactive Intestinal Peptide in Early Spondyloarthritis: Low Serum Levels as a Potential Biomarker for Disease Severity
JOURNAL OF MOLECULAR NEUROSCIENCE. Article. 56(3):577-584.
[doi:10.1007/s12031-015-0517-6]
Jimeno, Rebeca, Gomariz, Rosa P., Garin, Marina, Gutierrez-Canas, Irene, Gonzalez-Alvaro, Isidoro, Carrion, Mar, Galindo, Maria, Leceta, Javier, Juarranz, Yasmina (2015).
The pathogenic Th profile of human activated memory Th cells in early rheumatoid arthritis can be modulated by VIP
JOURNAL OF MOLECULAR MEDICINE-JMM. Article. 93(4):457-467.
[doi:10.1007/s00109-014-1232-4]
Gonzalez-Alvaro, I., Ortiz, A. M., Seoane, I. V., Garcia-Vicuna, R., Martinez, C., Gomariz, R. P. (2015).
Biomarkers Predicting a Need for Intensive Treatment in Patients with Early Arthritis
CURRENT PHARMACEUTICAL DESIGN. Review. 21(2):170-181.
Gomariz RP, Gonzalez-Alvaro I (2015).
Thematic issue: optimizing treatment in rheumatoid arthritis.
CURRENT PHARMACEUTICAL DESIGN. Editorial Material. 21(2):129-129.
2014
Jimeno, Rebeca, Leceta, Javier, Martinez, Carmen, Gutierrez-Canas, Irene, Carrion, Mar, Perez-Garcia, Selene, Garin, Marina, Mellado, Mario, Gomariz, Rosa P., Juarranz, Yasmina (2014).
Vasoactive Intestinal Peptide Maintains the Nonpathogenic Profile of Human Th17-Polarized Cells
JOURNAL OF MOLECULAR NEUROSCIENCE. Article. 54(3):512-525.
[doi:10.1007/s12031-014-0318-3]
Lamana, Amalia, Valino-Seoane, Iria, Rodriguez-Rodriguez, Luis, Leceta, Javier, Juarranz, Yasmina, Ortiz Garcia, Ana M., Martinez-Mora, Carmen, Fernandez-Gutierrez, Benjamin, Gonzalez-Alvaro, Isidoro, Gomariz, Rosa P., Garcia-Vicuna, Rosario (2014).
Vasoactive Intestinal Peptide (VIP) Genetic Variants Determine VIP Serum Levels and Could be Used As a Prognosis Biomarker.
ARTHRITIS & RHEUMATOLOGY. Meeting Abstract. 66(10, SI):500-500.
Tomero, E., Seoane, I. V., Martinez, C., Juarranz, Y., Ortiz, A. M., Garcia-Vicuna, R., Gomariz, R. P., Gonzalez-Alvaro, I. (2014).
VASOACTIVE INTESTINAL PEPTIDE IN SERUM: A POTENTIAL DISEASE SEVERITY MARKER IN PATIENTS WITH EARLY SPONDYLOARTHRITIS
ANNALS OF THE RHEUMATIC DISEASES. Meeting Abstract. 73(2):203-203.
[doi:10.1136/annrheumdis-2014-eular.4454]
Ortiz, A. M., Piris, L., Gonzalez-Alvaro, I., Seoane, I. V., Lamana, A., Juarranz, Y., Leceta, J., Gomariz, R. P., Martinez, C. (2014).
THE EXPRESSION OF VIP RECEPTORS, VPAC1 AND VPAC2, IS RELATED TO DISEASE ACTIVITY IN PATIENTS WITH EARLY ARTHRITIS
ANNALS OF THE RHEUMATIC DISEASES. Meeting Abstract. 73(2):839-839.
[doi:10.1136/annrheumdis-2014-eular.3472]
Martinez, Carmen, Ortiz, Ana M., Juarranz, Yasmina, Lamana, Amalia, Seoane, Iria V., Leceta, Javier, Garcia-Vicuna, Rosario, Gomariz, Rosa P., Gonzalez-Alvaro, Isidoro (2014).
Serum Levels of Vasoactive Intestinal Peptide as a Prognostic Marker in Early Arthritis
PLOS ONE. Article. 9(1).
[doi:10.1371/journal.pone.0085248]
Perez-Garcia, Selene, Carrion, Mar, Jimeno, Rebeca, Ortiz, Ana M., Gonzalez-Alvaro, Isidoro, Fernandez, Julin, Gomariz, Rosa P., Juarranz, Yasmina (2014).
Urokinase Plasminogen Activator System in Synovial Fibroblasts from Osteoarthritis Patients: Modulation by Inflammatory Mediators and Neuropeptides
JOURNAL OF MOLECULAR NEUROSCIENCE. Article. 52(1):18-27.
[doi:10.1007/s12031-013-0189-z]
