Neurotraumatology and Subarachnoid Hemorrhage

Description

This group focus its activity in the investigation of traumatic brain injury and cerebrovascular pathology.

Nowadays this group has three main investigation lines:

1. Traumatic brain injury.
2. Cerebrovascular pathology.
3. Spine pathology and traumatic spinal cord injury.

The main general objectives of these lines are the design of prognostic models and the discovery of new biological and imaging prognostic factors, and the assessment of their role on these pathologies.

The specific objectives of each line are:

 Line 1. Traumatic brain injury:

1. Design of prognostic models in TBI.
2. New prognostic factors in TBI:
   1. Conventional MR and advanced techniques (diffusion MR and tractography).
   2. Volumetric analysis of the lesions and CT patterns.
   3. Biomarkers
   4. Role of inflammation in TBI.
3. Factors related to contusion appearance and growth of traumatic lesions after TBI.
4. Neuropsychological involvement after TBI and its relation to brain structural damage. Factors related to the evolution of neuropsychological damage.
5. Quality of life after TBI. Development of specific instruments of assessment.
6. Effects of decompressive craniectomy:
   1. Pathophysiology of the craniectomised brain.
   2. Decompressive craniectomy in TBI: results.
   3. Effects of cranioplasty in the physiology of cerebral blood flow and improvement of neurological function.
7. TBI: Cost analysis.

Line 2: Cerebrovascular Pathology

1. Prognostic models in subarachnoid hemorrhage and spontaneous intracerebral hemorrhage.
2. New prognostic factors in brain hemorrhage: Bioological and imaging markers.
3. Genesis, development and rupture of cerebral aneurysms: Genetics, anatomy and hemodynamics.
4. Neuropsychological damage and quality of life after subarachnoid hemorrhage.
5. Cost analysis of Subarachnoid hemorrhage.
6. Angioarchitectural features related to the development, growth and ruptura of arteriovenous malformations.
7. Quality of life after decompressive craniectomy for brain infaction.

Line 3: Spinal pathology and traumatic spinal cord injury.

1. Factors related to outcome of spinal cord injury: MR imaging and spinal cord injury.
2. New approaches in spinal cord surgery: Role of minimally invasive approaches.
3. Economic impact of lumbar spinal surgery.