Regulation of Cellular Homeostasis |

Publications

2023

Gabande-Rodriguez, E, Pfeiffer, M, Mittelbrunn, M (2023).

Immuno(T)herapy for age-related diseases

EMBO MOLECULAR MEDICINE. Editorial Material. 15(1).
[doi:10.15252/emmm.202216301]

2022

Navarro MN, Gómez de Las Heras MM, Mittelbrunn M (2022).

Nicotinamide adenine dinucleotide metabolism in the immune response, autoimmunity and inflammageing.

BRITISH JOURNAL OF PHARMACOLOGY. Review. 179(9):1839-1856.
[doi:10.1111/bph.15477]

Oller, J, Gabande-Rodriguez, E, Roldan-Montero, R, Ruiz-Rodriguez, MJ, Redondo, JM, Martin-Ventura, JL, Mittelbrunn, M (2022).

Rewiring Vascular Metabolism Prevents Sudden Death due to Aortic Ruptures-Brief Report

ARTERIOSCLEROSIS THROMBOSIS AND VASCULAR BIOLOGY. Article. 42(4):462-469.
[doi:10.1161/ATVBAHA.121.317346]

Roldán-Montero R, Pérez-Sáez JM, Cerro-Pardo I, Oller J, Martinez-Lopez D, Nuñez E, Maller SM, Gutierrez-Muñoz C, Mendez-Barbero N, Escola-Gil JC, Michel JB, Mittelbrunn M, Vázquez J, Blanco-Colio LM, Rabinovich GA, Martin-Ventura JL (2022).

Galectin-1 prevents pathological vascular remodeling in atherosclerosis and abdominal aortic aneurysm.

Science Advances. Article. 8(11).
[doi:10.1126/sciadv.abm7322]

Carrasco, E, Gómez de Las Heras MM, Gabande-Rodriguez, E, Desdin-Mico, G, Aranda, JF, Mittelbrunn, M (2022).

The role of T cells in age-related diseases.

NATURE REVIEWS IMMUNOLOGY. Review. 22(2):97-111.
[doi:10.1038/s41577-021-00557-4]

2021

Del Rey MJ, Meroño C, Municio C, Usategui A, Mittelbrunn M, García-Consuegra I, Criado G, Pablos JL (2021).

TFAM-deficient mouse skin fibroblasts - an ex vivo model of mitochondrial dysfunction.

DISEASE MODELS & MECHANISMS. Article. 14(8).
[doi:10.1242/dmm.048995]

Mittelbrunn M, Kroemer G (2021).

Hallmarks of T cell aging.

NATURE IMMUNOLOGY. Review. 22(6):687-698.
[doi:10.1038/s41590-021-00927-z]

Oller J, Gabandé-Rodríguez E, Ruiz-Rodríguez MJ, Desdín-Micó G, Aranda JF, Rodrigues-Diez R, Ballesteros-Martínez C, Blanco EM, Roldan-Montero R, Acuña P, Forteza Gil A, Martín-López CE, Nistal JF, Lino Cardenas CL, Lindsay ME, Martín-Ventura JL, Briones AM, Miguel Redondo J, Mittelbrunn M (2021).

Extracellular Tuning of Mitochondrial Respiration Leads to Aortic Aneurysm.

CIRCULATION. Article. 143(21):2091-2109.
[doi:10.1161/CIRCULATIONAHA.120.051171]

Soto-Heredero G, Desdín-Micó G, Mittelbrunn M (2021).

Mitochondrial dysfunction defines T cell exhaustion.

CELL METABOLISM. Editorial Material. 33(3):470-472.
[doi:10.1016/j.cmet.2021.02.010]

Marquez-Exposito, L, Rodrigues-Diez, RR, Rayego-Mateos, S, Fierro-Fernandez, M, Rodrigues-Diez, R, Orejudo, M, Santos-Sanchez, L, Blanco, EM, Laborda, J, Mezzano, S, Lamas, S, Lavoz, C, Ruiz-Ortega, M (2021).

Deletion of delta-like 1 homologue accelerates renal inflammation by modulating the Th17 immune response

FASEB JOURNAL. Article. 35(1).
[doi:10.1096/fj.201903131R]

2020

Soto-Heredero, G, Gómez de Las Heras MM, Gabandé-Rodríguez, E, Oller, J, Mittelbrunn, M (2020).

Glycolysis - a key player in the inflammatory response.

FEBS JOURNAL. Review. 287(16):3350-3369.
[doi:10.1111/febs.15327]

Desdin-Mico, G, Soto-Heredero, G, Aranda, JF, Oller, J, Carrasco, E, Gabande-Rodriguez, E, Blanco, EM, Alfranca, A, Cusso, L, Desco, M, Ibanez, B, Gortazar, AR, Fernandez-Marcos, P, Navarro, MN, Hernaez, B, Alcami, A, Baixauli, F, Mittelbrunn, M (2020).

T cells with dysfunctional mitochondria induce multimorbidity and premature senescence

Science. Article. 368(6497):1371.
[doi:10.1126/science.aax0860]

Gabande-Rodriguez, E, M Gomez de Las Heras M, Mittelbrunn, M (2020).

Control of Inflammation by Calorie Restriction Mimetics: On the Crossroad of Autophagy and Mitochondria.

Cells. Review. 9(1).
[doi:10.3390/cells9010082]

2019

Carrasco, E, Soto-Heredero, G, Mittelbrunn, M (2019).

The Role of Extracellular Vesicles in Cutaneous Remodeling and Hair Follicle Dynamics.

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 20(11).
[doi:10.3390/ijms20112758]

2018

Caravia, XM, Fanjul, V, Oliver, E, Roiz-Valle, D, Moran-Alvarez, A, Desdin-Mico, G, Mittelbrunn, M, Cabo, R, Vega, JA, Rodriguez, F, Fueyo, A, Gomez, M, Lobo-Gonzalez, M, Bueno, H, Velasco, G, Freije JMP, Andres, V, Ibanez, B, Ugalde, AP, Lopez-Otin, C (2018).

The microRNA-29/PGC1 alpha regulatory axis is critical for metabolic control of cardiac function

PLOS BIOLOGY. Article. 16(10).
[doi:10.1371/journal.pbio.2006247]

Torralba, D, Baixauli, F, Villarroya-Beltri, C, Fernandez-Delgado, I, Latorre-Pellicer, A, Acin-Perez, R, Martin-Cofreces, NB, Jaso-Tamame, AL, Iborra, S, Jorge, I, Gonzalez-Aseguinolaza, G, Garaude, J, Vicente-Manzanares, M, Enriquez, JA, Mittelbrunn, M, Sanchez-Madrid, F (2018).

Priming of dendritic cells by DNA-containing extracellular vesicles from activated T cells through antigen-driven contacts

NATURE COMMUNICATIONS. Article. 9(1):2658-2658.
[doi:10.1038/s41467-018-05077-9]

Desdin-Mico, G, Soto-Heredero, G, Mittelbrunn, M (2018).

Mitochondrial activity in T cells

MITOCHONDRION. Review. 41:51-57.
[doi:10.1016/j.mito.2017.10.006]

2017

Soto-Heredero G, Baixauli F, Mittelbrunn M (2017).

Interorganelle Communication between Mitochondria and the Endolysosomal System.

Frontiers In Cell And Developmental Biology. Article. 5:95-95.
[doi:10.3389/fcell.2017.00095]

Gutiérrez-Vázquez C, Rodríguez-Galán A, Fernández-Alfara M, Mittelbrunn M, Sánchez-Cabo F, Martínez-Herrera DJ, Ramírez-Huesca M, Pascual-Montano A, Sánchez-Madrid F (2017).

miRNA profiling during antigen-dependent T cell activation: A role for miR-132-3p

SCIENTIFIC REPORTS. Article. 7(1):3508-3508.
[doi:10.1038/s41598-017-03689-7]

Gutiérrez-Vázquez C, Enright AJ, Rodríguez-Galán A, Pérez-García A, Collier P, Jones MR, Benes V, Mizgerd JP, Mittelbrunn M, Ramiro AR, Sánchez-Madrid F (2017).

3 ' Uridylation controls mature microRNA turnover during CD4 T-cell; activation

RNA. Article. 23(6):882-891.
[doi:10.1261/rna.060095.116]

Mateescu B, Kowal EJ, van Balkom BW, Bartel S, Bhattacharyya SN, Buzás EI, Buck AH, de Candia P, Chow FW, Das S, Driedonks TA, Fernández-Messina L, Haderk F, Hill AF, Jones JC, Van Keuren-Jensen KR, Lai CP, Lässer C, Liegro ID, Lunavat TR, Lorenowicz MJ, Maas SL, Mäger I, Mittelbrunn M, Momma S, Mukherjee K, Nawaz M, Pegtel DM, Pfaffl MW, Schiffelers RM, Tahara H, Théry C, Tosar JP, Wauben MH, Witwer KW, Nolte-'t Hoen EN (2017).

Obstacles and opportunities in the functional analysis of extracellular; vesicle RNA - an ISEV position paper

Journal of extracellular vesicles. Article. 6(1):1286095-1286095.
[doi:10.1080/20013078.2017.1286095]