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Toxicologia y Seguridad de Agentes Químicos y Biológicos

Publicaciones

2023

Xu, XQ, Yu, YX, Ling, M, Ares, I, Martínez, M, Lopez-Torres, B, Maximiliano, JE, Martínez-Larrañaga, MR, Wang, X, Anadón, A, Martínez, MA (2023).

Oxidative stress and mitochondrial damage in lambda-cyhalothrin toxicity: A comprehensive review of antioxidant mechanisms

ENVIRONMENTAL POLLUTION. Review. 338.
[doi:10.1016/j.envpol.2023.122694]
Feng, J, Zheng, YL, Guo, MY, Ares, I, Martínez, M, Lopez-Torres, B, Martínez-Larranaga, MR, Wang, X, Anadón, A, Martínez, MA (2023).

Oxidative stress, the blood-brain barrier and neurodegenerative diseases: The critical beneficial role of dietary antioxidants

Acta Pharmaceutica Sinica B. Review. 13(10):3988-4024.
[doi:10.1016/j.apsb.2023.07.010]
Badawy, S, Liu, YA, Guo, MY, Liu, ZL, Xie, CQ, Marawan, MA, Ares, I, Lopez-Torres, B, Martinez, M, Maximiliano, JE, Martínez-Larrañaga, MR, Wang, X, Anadón, A, Martínez, MA (2023).

Conjugated linoleic acid (CLA) as a functional food: Is it beneficial or not?

FOOD RESEARCH INTERNATIONAL. Review. 172.
[doi:10.1016/j.foodres.2023.113158]
Zhao, YX, Ye, XC, Xiong, ZF, Ihsan, A, Ares, I, Martínez, M, Lopez-Torres, B, Martínez-Larrañaga, MR, Anadón, A, Wang, X, Martínez, MA (2023).

Cancer Metabolism: The Role of ROS in DNA Damage and Induction of Apoptosis in Cancer Cells

Metabolites. Review. 13(7).
[doi:10.3390/metabo13070796]
Ye, XC, Zhao, YX, Ma, WQ, Ares, I, Martínez, M, Lopez-Torres, B, Martínez-Larrañaga, MR, Wang, X, Anadón, A, Martínez, MA (2023).

The potential of CD38 protein as a target for autoimmune diseases

AUTOIMMUNITY REVIEWS. Article. 22(4).
[doi:10.1016/j.autrev.2023.103289]
Wang X, Li H, Wang S, Martínez MA, Ares I, Martínez M, Martínez-Larrañaga MR, Wang X, Anadón A, Maximiliano JE (2023).

Tefluthrin: metabolism, food residues, toxicity, and mechanisms of action.

CRITICAL REVIEWS IN TOXICOLOGY. Article. 52(8):664-680.
[doi:10.1080/10408444.2022.2143320]

2022

Lopez-Torres, B, Ares, I, Martinez, M, Maximiliano, JE, Martinez-Larranaga, MR, Anadon, A, Martinez, MA (2022).

Neurotoxicity induced by the pyrethroid lambda-cyhalothrin: Alterations in monoaminergic systems and dopaminergic and serotoninergic pathways in the rat brain.

FOOD AND CHEMICAL TOXICOLOGY. Article. 169:113434-113434.
[doi:10.1016/j.fct.2022.113434]
Xu, XQ, Liu, YN, Guo, MY, Martinez, MA, Ares, I, Lopez-Torres, B, Martinez-Larranaga, MR, Wang, X, Anadon, A, Martinez, M (2022).

The "steric-like" inhibitory effect and mechanism of doxycycline on florfenicol metabolism: Interaction risk.

FOOD AND CHEMICAL TOXICOLOGY. Article. 169:113431-113431.
[doi:10.1016/j.fct.2022.113431]
Xu X, Wang X, Yang Y, Ares I, Martínez M, Lopez-Torres B, Martínez-Larrañaga MR, Wang X, Anadón A, Martinez MA (2022).

Neonicotinoids: mechanisms of systemic toxicity based on oxidative stress-mitochondrial damage.

ARCHIVES OF TOXICOLOGY. Review. 96(6):1493-1520.
[doi:10.1007/s00204-022-03267-5]
Liu A, Guo M, He L, Martínez MA, Martínez M, Lopez-Torres B, Martínez-Larrañaga MR, Wang X, Anadón A, Ares I (2022).

Nicotinamide N-methyltransferase protects against deoxynivalenol-induced growth inhibition by suppressing pro-inflammatory cytokine expression.

FOOD AND CHEMICAL TOXICOLOGY. Article. 163:112969-112969.
[doi:10.1016/j.fct.2022.112969]
Feng J, Wang X, Ye X, Ares I, Lopez-Torres B, Martínez M, Martínez-Larrañaga MR, Wang X, Anadón A, Martínez MA (2022).

Mitochondria as an important target of metformin: The mechanism of action, toxic and side effects, and new therapeutic applications.

PHARMACOLOGICAL RESEARCH. Review. 177:106114-106114.
[doi:10.1016/j.phrs.2022.106114]
Wang X, Lu Q, Guo J, Ares I, Martínez M, Martínez-Larrañaga MR, Wang X, Anadón A, Martínez MA (2022).

Oxidative Stress and Metabolism: A Mechanistic Insight for Glyphosate Toxicology.

ANNUAL REVIEW OF PHARMACOLOGY AND TOXICOLOGY. Review. 62:617-639.
[doi:10.1146/annurev-pharmtox-020821-111552]
Liu, AM, Zhou, KX, Martinez, MA, Lopez-Torres, B, Martinez, M, Martinez-Larraaga, MR, Wang, X, Anadon, A, Ares, I (2022).

A "Janus" face of the RASSF4 signal in cell fate.

JOURNAL OF CELLULAR PHYSIOLOGY. Review. 237(1):466-479.
[doi:10.1002/jcp.30592]

2021

Guo, P, Lu, QR, Hu, SY, Martinez, MA, Lopez-Torres, B, Martinez, M, Martinez-Larranaga, MR, Wang, X, Anadon, A, Ares, I (2021).

The NO-dependent caspase signaling pathway is a target of deoxynivalenol in growth inhibition in vitro

FOOD AND CHEMICAL TOXICOLOGY. Article. 158.
[doi:10.1016/j.fct.2021.112629]
Xu, XQ, Lu, QR, Yang, YQ, Martinez, MA, Lopez-Torres, B, Martinez-Larranaga, MR, Wang, X, Anadon, A, Ares, I (2021).

A proposed "steric-like effect" for the slowdown of enrofloxacin antibiotic metabolism by ciprofloxacin, and its mechanism

Chemosphere. Article. 284.
[doi:10.1016/j.chemosphere.2021.131347]
Badawy, S, Yang, YQ, Liu, YN, Marawan, MA, Ares, I, Martinez, MA, Martinez-Larranaga, MR, Wang, X, Anadon, A, Martinez, M (2021).

Toxicity induced by ciprofloxacin and enrofloxacin: oxidative stress and metabolism

CRITICAL REVIEWS IN TOXICOLOGY. Review. 51(9):754-787.
[doi:10.1080/10408444.2021.2024496]
Wang, XJ, Yang, YQ, Martinez, MA, Martinez, M, Lopez-Torres, B, Martinez-Larranaga, MR, Wang, X, Anadon, A, Ares, I (2021).

Interaction Between Florfenicol and Doxycycline Involving Cytochrome P450 3A in Goats (Capra hricus)

Frontiers in Veterinary Science. Article. 8.
[doi:10.3389/fvets.2021.759716]
Martinez, MA, Ares, I, Martinez, M, Lopez-Torres, B, Maximiliano, JE, Rodriguez, JL, Martinez-Larranaga, MR, Anadon, A, Peteiro, C, Rubino, S, Hortos, M (2021).

Brown marine algae Gongolaria baccata extract protects Caco-2 cells from oxidative stress induced by tert-butyl hydroperoxide

FOOD AND CHEMICAL TOXICOLOGY. Article. 156.
[doi:10.1016/j.fct.2021.112460]
Xu X, Liu A, Hu S, Ares I, Martínez-Larrañaga MR, Wang X, Martínez M, Anadón A, Martínez MA (2021).

Synthetic phenolic antioxidants: Metabolism, hazards and mechanism of action.

FOOD CHEMISTRY. Article. 353:129488-129488.
[doi:10.1016/j.foodchem.2021.129488]
Tarazona JV, Martínez M, Martínez MA, Anadón A (2021).

Environmental impact assessment of COVID-19 therapeutic solutions. A prospective analysis

SCIENCE OF THE TOTAL ENVIRONMENT. Article. 778:146257-146257.
[doi:10.1016/j.scitotenv.2021.146257]
Lu Q, Guo P, Liu A, Ares I, Martínez-Larrañaga MR, Wang X, Anadón A, Martínez MA (2021).

The role of long noncoding RNA in lipid, cholesterol, and glucose metabolism and treatment of obesity syndrome.

MEDICINAL RESEARCH REVIEWS. Review. 41(3):1751-1774.
[doi:10.1002/med.21775]
Lu, QR, Guo, P, Guo, JC, Ares, I, Lopez-Torres, B, Martinez-Larranaga, MR, Wang, X, Anadon, A, Martinez, MA (2021).

Targeting peroxisome proliferator-activated receptors: A new strategy for the treatment of cardiac fibrosis.

PHARMACOLOGY & THERAPEUTICS. Review. 219:107702-107702.
[doi:10.1016/j.pharmthera.2020.107702]
De Briyne, N, Holmes, D, Sandler, I, Stiles, E, Szymanski, D, Moody, S, Neumann, S, Anadon, A (2021).

Cannabis, Cannabidiol Oils and Tetrahydrocannabinol-What Do Veterinarians Need to Know?

Animals. Review. 11(3).
[doi:10.3390/ani11030892]
Bonassa, KPD, Miragliotta, MY, Simas, RC, Eberlin, MN, Anadon, A, Moreno, RA, Reyes, FGR (2021).

Pharmacokinetics, Pharmacodynamic Efficacy Prediction Indexes and Monte Carlo Simulations of Enrofloxacin Hydrochloride Against Bacterial Strains That Induce Common Clinical Diseases in Broiler Chickens

Frontiers in Veterinary Science. Article. 7.
[doi:10.3389/fvets.2020.606872]

2020

Martínez MA, Ares I, Martínez M, Lopez-Torres B, Rodríguez JL, Maximiliano JE, Martínez-Larrañaga MR, Anadón A, Rosa JM, Cueto M (2020).

Protective effects of culture extracts (CB08035-SCA and CB08035-SYP) from Marinobacter hydrocarbonoclasticus (strain CB08035) against oxidant-induced stress in human colon carcinoma Caco-2 cells.

FOOD AND CHEMICAL TOXICOLOGY. Article. 145:111671-111671.
[doi:10.1016/j.fct.2020.111671]
Liu A, Hu S, Wu Q, Ares I, Martínez M, Martínez-Larrañaga MR, Anadón A, Wang X, Martínez MA (2020).

Epigenetic upregulation of galanin-like peptide mediates deoxynivalenol induced-growth inhibition in pituitary cells.

TOXICOLOGY AND APPLIED PHARMACOLOGY. Article. 403:115166-115166.
[doi:10.1016/j.taap.2020.115166]
Liu, AM, Wu, QH, Peng, DP, Ares, I, Anadon, A, Lopez-Torres, B, Martinez-Larranaga, MR, Wang, X, Martinez, MA (2020).

A novel strategy for the diagnosis, prognosis, treatment, and chemoresistance of hepatocellular carcinoma: DNA methylation.

MEDICINAL RESEARCH REVIEWS. Review. 40(5):1973-2018.
[doi:10.1002/med.21696]
Caloni F, Fossati P, Anadón A, Bertero A (2020).

Beauvericin: The beauty and the beast.

ENVIRONMENTAL TOXICOLOGY AND PHARMACOLOGY. Article. 75:103349-103349.
[doi:10.1016/j.etap.2020.103349]
Marcos A, Moreno M, Orihuel J, Ucha M, Mª de Paz A, Higuera-Matas A, Capellán R, Crego AL, Martínez-Larrañaga MR, Ambrosio E, Anadón A (2020).

The effects of combined intravenous cocaine and ethanol self-administration on the behavioral and amino acid profile of young adult rats.

PLOS ONE. Article. 15(3).
[doi:10.1371/journal.pone.0227044]
Martínez MA, Lopez-Torres B, Rodríguez JL, Martínez M, Maximiliano JE, Martínez-Larrañaga MR, Anadón A, Ares I (2020).

Toxicologic evidence of developmental neurotoxicity of Type II pyrethroids cyfluthrin and alpha-cypermethrin in SH-SY5Y cells.

FOOD AND CHEMICAL TOXICOLOGY. Article. 137:111173-111173.
[doi:10.1016/j.fct.2020.111173]
Martínez MA, Rodríguez JL, Lopez-Torres B, Martínez M, Martínez-Larrañaga MR, Maximiliano JE, Anadón A, Ares I (2020).

Use of human neuroblastoma SH-SY5Y cells to evaluate glyphosate-induced effects on oxidative stress, neuronal development and cell death signaling pathways.

ENVIRONMENT INTERNATIONAL. Article. 135:105414-105414.
[doi:10.1016/j.envint.2019.105414]

Lu, QR, Guo, P, Wang, XH, Ares, I, Lopez-Torres, B, Martinez-Larranaga, MR, Li, TT, Zhang, YY, Wang, X, Anadon, A, Martinez, MA ().

MS4A3-HSP27 target pathway reveals potential for haematopoietic disorder treatment in alimentary toxic aleukia

CELL BIOLOGY AND TOXICOLOGY. Article.
[doi:10.1007/s10565-021-09639-4]