Publicaciones
2023
de Lope-Planelles, A, González-Novo, R, Madrazo, E, Peralta-Carrero, G, Rodríguez, MPC, Zamora-Carreras, H, Torrano, V, López-Menéndez, H, Roda-Navarro, P, Monroy, F, Redondo-Muñoz, J (2023).
Mechanical stress confers nuclear and functional changes in derived leukemia cells from persistent confined migration
CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 80(11).
[doi:10.1007/s00018-023-04968-5]
Fuertes, T, Alvarez-Corrales, E, Gómez-Escolar, C, Ubieto-Capella, P, Serrano-Navarro, A, de Molina, A, Méndez, J, Ramiro, AR, de Ybenes, VG (2023).
miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication
CELL DEATH & DISEASE. Article. 14(10).
[doi:10.1038/s41419-023-06178-0]
Zheng, K, Hao, FJ, Medrano-Garcia, S, Chen, CB, Guo, FF, Morán-Blanco, L, Rodríguez-Perales, S, Torres-Ruiz, R, Peligros, MI, Vaquero, J, Bañares, R, del Moral, MG, Regueiro, JR, Martínez-Naves, E, Mohamed, MR, Gallego-Durán, R, Maya, D, Ampuero, J, Romero-Gómez, M, Gilbert-Ramos, A, Guixé-Muntet, S, Fernández-Iglesias, A, Gracia-Sancho, J, Coll, M, Graupera, I, Ginès, P, Ciudin, A, Rivera-Esteban, J, Pericàs, JM, Frutos, MD, Molina, BR, Herranz, JM, Avila, MA, Nevzorova, YA, Fernández-Malavé, E, Cubero, FJ (2023).
Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis
CELL DEATH & DISEASE. Article. 14(8).
[doi:10.1038/s41419-023-06029-y]
Vera-Zambrano, A, Lago-Docampo, M, Gallego, N, Franco-Gonzalez, JF, Morales-Cano, D, Cruz-Utrilla, A, Villegas-Esguevillas, M, Fernández-Malavé, E, Escribano-Subías, P, Tenorio-Castaño, JA, Perez-Vizcaino, F, Valverde, D, González, T, Cogolludo, A (2023).
Novel Loss-of-Function KCNA5 Variants in Pulmonary Arterial Hypertension
AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. Article. 69(2):147-158.
[doi:10.1165/rcmb.2022-0245OC]
Martín-Adrados, B, Wculek, SK, Fernández-Bravo, S, Torres-Ruiz, R, Valle-Noguera, A, Gomez-Sánchez, MJ, Hernández-Walias, JC, Ferreira, FM, Corraliza, AM, Sancho, D, Esteban, V, Rodriguez-Perales, S, Cruz-Adalia, A, Nakaya, HI, Salas, A, Bernardo, D, Campos-Martín, Y, Martínez-Zamorano, E, Muñoz-López, D, del Moral, MG, Cubero, FJ, Blumberg, RS, Martínez-Naves, E (2023).
Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress
Frontiers in immunology. Article. 14.
[doi:10.3389/fimmu.2023.1185517]
Natalini, A, Simonetti, S, Favaretto, G, Lucantonio, L, Peruzzi, G, Munoz-Ruiz, M, Kelly, G, Contino, AM, Sbrocchi, R, Battella, S, Capone, S, Folgori, A, Nicosia, A, Santoni, A, Hayday, AC, Di Rosa, F (2023).
Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature (vol 14, 1043631, 2023)
Frontiers in immunology. Correction. 14.
[doi:10.3389/fimmu.2023.1199754]
Fiyouzi, T, Pelaez-Prestel, HF, Reyes-Manzanas, R, Lafuente, EM, Reche, PA (2023).
Students' Perceptions of Their Student-Operated Restaurant Experience: A Qualitative Study
International Journal Of Molecular Sciences. Review. 24(9).
[doi:10.3390/ijms24097797]
Sanz-Garcia, Carlos, Nevzorova, Yulia A, Martinez-Naves, Eduardo, Cubero, Francisco Javier, Hionides-Gutierrez, Alejandro, Sanudo, Jose Ramon, Enrich, Carlos, Rentero, Carles, Sancho-Bru, Pau, Macias-Rodriguez, Ricardo U, Ruiz-Margain, Astrid, Kershenobich-Stalnikowitz, David, Vargas, Nestor R, Munoz, Alberto E, Nakaya, Helder I (2023).
Novel therapeutic avenues for the study of chronic liver disease and regeneration: The foundation of the Iberoamerican Consortium for the study of liver Cirrhosis.
GASTROENTEROLOGIA Y HEPATOLOGIA. Article. 46(4):322-328.
[doi:10.1016/j.gastrohep.2022.05.012]
Toribio, ML, González-García, S (2023).
Notch Partners in the Long Journey of T-ALL Pathogenesis
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 24(2).
[doi:10.3390/ijms24021383]
2022
Carrasco-Padilla, C, Hernaiz-Esteban, A, alvarez-Vallina, L, Aguilar-Sopena, O, Roda-Navarro, P (2022).
Bispecific Antibody Format and the Organization of Immunological Synapses in T Cell-Redirecting Strategies for Cancer Immunotherapy.
Pharmaceutics. Review. 15(1).
[doi:10.3390/pharmaceutics15010132]
Cook ECL, Redondo-Urzainqui A, Iborra S (2022).
Obesity can turn a therapy into an antitherapy in atopic dermatitis.
ALLERGY. News Item. 77(11):3473-3475.
[doi:10.1111/all.15482]
Caravaca-Fontán F, Lucientes L, Serra N, Cavero T, Rodado R, Ramos N, Gonzalez F, Shabaka A, Cabello V, Huerta A, Pampa-Saico S, Gutiérrez E, Quintana LF, López-Rubio ME, Draibe J, Titos JA, Fernández-Juárez G, de Jorge EG, Praga M (2022).
C3 glomerulopathy associated with monoclonal gammopathy: impact of chronic histologic lesions and beneficial effects of clone-targeted therapies.
NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 37(11):2128-2137.
[doi:10.1093/ndt/gfab302]
Marin, AV, Jimenez-Reinoso, A, Mazariegos, MS, Roman-Ortiz, E, Regueiro, JR (2022).
T-cell receptor signaling in Schimke immuno-osseous dysplasia is SMARCAL1-independent.
Frontiers in immunology. Article. 13:979722-979722.
[doi:10.3389/fimmu.2022.979722]
Castillo-Gonzalez, R, Valle-Noguera, A, Gomez-Sanchez, MJ, Xia, P, Cruz-Adalia, A (2022).
Innate lymphoid cells type 3 in cancer.
Frontiers in immunology. Review. 13:1033252-1033252.
[doi:10.3389/fimmu.2022.1033252]
Torres-Gomez, A, Fiyouzi, T, Guerra-Espinosa, C, Cardenes, B, Clares, I, Toribio, V, Reche, PA, Cabanas, C, Lafuente, EM (2022).
Expression of the phagocytic receptors alpha(M)beta(2) and alpha(X)beta(2) is controlled by RIAM, VASP and Vinculin in neutrophil-differentiated HL-60 cells
Frontiers in immunology. Article. 13:951280-951280.
[doi:10.3389/fimmu.2022.951280]
Garcillán B, Megino RF, Herrero-Alonso M, Guardo AC, Perez-Flores V, Juraske C, Idstein V, Martin-Fernandez JM, Geisler C, Schamel WWA, Marin AV, Regueiro JR (2022).
The role of the different CD3? domains in TCR expression and signaling.
Frontiers in immunology. Article. 13:978658-978658.
[doi:10.3389/fimmu.2022.978658]
Ras-Carmona A, Lehmann AA, Lehmann PV, Reche PA (2022).
Prediction of B cell epitopes in proteins using a novel sequence similarity-based method.
SCIENTIFIC REPORTS. Article. 12(1):13739-13739.
[doi:10.1038/s41598-022-18021-1]
Medrano-Garcia S, Morales-Cano D, Barreira B, Vera-Zambrano A, Kumar R, Kosanovic D, Schermuly RT, Graham BB, Perez-Vizcaino F, Mathie A, Savai R, Pullamseti S, Butrous G, Fernández-Malavé E, Cogolludo A (2022).
HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape.
Cells. Article. 11(15).
[doi:10.3390/cells11152414]
Caravaca-Fontán F, Díaz-Encarnación M, Cabello V, Ariceta G, Quintana LF, Marco H, Barros X, Ramos N, Rodríguez-Mendiola N, Cruz S, Fernández-Juárez G, Rodríguez A, de José AP, Rabasco C, Rodado R, Fernández L, Gómez VP, Ávila A, Bravo L, Espinosa N, Allende N, Sanchez de la Nieta MD, Rodríguez E, Olea T, Melgosa M, Huerta A, Miquel R, Mon C, Fraga G, de Lorenzo A, Draibe J, Cano-Megías M, González F, Shabaka A, López-Rubio ME, Fenollosa MÁ, Martín-Penagos L, Da Silva I, Titos JA, de Córdoba SR, de Jorge EG, Praga M (2022).
Longitudinal change in proteinuria and kidney outcomes in C3 glomerulopathy.
NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 37(7):1270-1280.
[doi:10.1093/ndt/gfab075]
Gallardo F, Andrades E, Iglesias A, González J, Solé L, Guillén Y, Blanco G, Colomo L, Gimeno E, Conde D, Rodriguez E, Bielsa-Marso I, Iglesias M, Bellosillo B, Pujol RM, Regueiro JR, Bigas A, Espinosa L (2022).
Sézary syndrome patient-derived models allow drug selection for personalized therapy.
Blood Advances. Article. 6(11):3410-3421.
[doi:10.1182/bloodadvances.2021006860]
García-Cuesta EM, Rodríguez-Frade JM, Gardeta SR, D'Agostino G, Martínez P, Soler Palacios B, Cascio G, Wolf T, Mateos N, Ayala-Bueno R, Santiago CA, Lucas P, Llorente L, Allende LM, González-Granado LI, Martín-Cófreces N, Roda-Navarro P, Sallusto F, Sánchez-Madrid F, García-Parajo MF, Martínez-Muñoz L, Mellado M (2022).
Altered CXCR4 dynamics at the cell membrane impairs directed cell migration in WHIM syndrome patients.
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Article. 119(21):2119483119-2119483119.
[doi:10.1073/pnas.2119483119]
Cardeñes B, Clares I, Bezos T, Toribio V, López-Martín S, Rocha A, Peinado H, Yáñez-Mó M, Cabañas C (2022).
ALCAM/CD166 Is Involved in the Binding and Uptake of Cancer-Derived Extracellular Vesicles.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 23(10).
[doi:10.3390/ijms23105753]
Ballesteros-Sanabria L, Pelaez-Prestel HF, Ras-Carmona A, Reche PA (2022).
Resilience of Spike-Specific Immunity Induced by COVID-19 Vaccines against SARS-CoV-2 Variants.
Biomedicines. Article. 10(5).
[doi:10.3390/biomedicines10050996]
Sari-Ak D, Torres-Gomez A, Yazicioglu YF, Christofides A, Patsoukis N, Lafuente EM, Boussiotis VA (2022).
Structural, biochemical, and functional properties of the Rap1-Interacting Adaptor Molecule (RIAM).
Biomedical Journal. Review. 45(2):289-298.
[doi:10.1016/j.bj.2021.09.005]
Carrasco-Padilla C, Roda-Navarro P (2022).
CRISPR/Cas9-mediated genome editing assists protein dynamics studies in live cells.
EUROPEAN JOURNAL OF CELL BIOLOGY. Article. 101(2):151203-151203.
[doi:10.1016/j.ejcb.2022.151203]
Blanco B, Ramírez-Fernández Á, Bueno C, Argemí-Muntadas L, Fuentes P, Aguilar-Sopeña Ó, Gutierrez-Agüera F, Zanetti SR, Tapia-Galisteo A, Díez-Alonso L, Segura-Tudela A, Castellà M, Marzal B, Betriu S, Harwood SL, Compte M, Lykkemark S, Erce-Llamazares A, Rubio-Pérez L, Jiménez-Reinoso A, Domínguez-Alonso C, Neves M, Morales P, Paz-Artal E, Guedan S, Sanz L, Toribio ML, Roda-Navarro P, Juan M, Menéndez P, Álvarez-Vallina L (2022).
Overcoming CAR-Mediated CD19 Downmodulation and Leukemia Relapse with T Lymphocytes Secreting Anti-CD19 T-cell Engagers.
Cancer Immunology Research. Article. 10(4):498-511.
[doi:10.1158/2326-6066.CIR-21-0853]
Solana JC, Moreno J, Iborra S, Soto M, Requena JM (2022).
Live attenuated vaccines, a favorable strategy to provide long-term immunity against protozoan diseases.
TRENDS IN PARASITOLOGY. Review. 38(4):316-334.
[doi:10.1016/j.pt.2021.11.004]
Ramírez-Fernández Á, Aguilar-Sopeña Ó, Díez-Alonso L, Segura-Tudela A, Domínguez-Alonso C, Roda-Navarro P, Álvarez-Vallina L, Blanco B (2022).
Synapse topology and downmodulation events determine the functional outcome of anti-CD19 T cell-redirecting strategies.
OncoImmunology. Article. 11(1):2054106-2054106.
[doi:10.1080/2162402X.2022.2054106]
Calatayud, David G., Jardiel, Teresa, Cordero-Oyonarte, Erica, Caballero, Amador C., Villegas, Marina, Valle-Noguera, Ana, Cruz-Adalia, Aranzazu, Peiteado, Marco (2022).
Biocompatible Probes Based on Rare-Earth Doped Strontium Aluminates with Long-Lasting Phosphorescent Properties for In Vitro Optical IMAGING
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 23(6).
[doi:10.3390/ijms23063410]
Garcillán B, Salavert M, Regueiro JR, Díaz-Castroverde S (2022).
Response to Vaccines in Patients with Immune-Mediated Inflammatory Diseases: A Narrative Review.
Vaccines. Review. 10(2).
[doi:10.3390/vaccines10020297]
Ye H, Chen C, Wu H, Zheng K, Martín-Adrados B, Caparros E, Francés R, Nelson LJ, Gómez del Moral M, Asensio I, Vaquero J, Bañares R, Ávila MA, Andrade RJ, Isabel Lucena M, Martínez-Chantar ML, Reeves HL, Masson S, Blumberg RS, Gracia-Sancho J, Nevzorova YA, Martínez-Naves E, Cubero FJ (2022).
Genetic and pharmacological inhibition of XBP1 protects against APAP hepatotoxicity through the activation of autophagy.
CELL DEATH & DISEASE. Article. 13(2):143-143.
[doi:10.1038/s41419-022-04580-8]
Tapia-Galisteo A, Sánchez Rodríguez Í, Aguilar-Sopeña O, Harwood SL, Narbona J, Ferreras Gutierrez M, Navarro R, Martín-García L, Corbacho C, Compte M, Lacadena J, Blanco FJ, Chames P, Roda-Navarro P, Álvarez-Vallina L, Sanz L (2022).
Trispecific T-cell engagers for dual tumor-targeting of colorectal cancer.
OncoImmunology. Article. 11(1):2034355-2034355.
[doi:10.1080/2162402X.2022.2034355]
Hernández-García E, Cueto FJ, Cook ECL, Redondo-Urzainqui A, Charro-Zanca S, Robles-Vera I, Conde-Garrosa R, Nikolic I, Sabio G, Sancho D, Iborra S (2022).
Conventional type 1 dendritic cells protect against age-related adipose tissue dysfunction and obesity.
CELLULAR & MOLECULAR IMMUNOLOGY. Article. 19(2):260-275.
[doi:10.1038/s41423-021-00812-7]
Ahmed AR, Anwar S, Reche PA (2022).
Molecular Basis for Global Incidence of Pemphigoid Diseases and Differences in Phenotypes.
Frontiers in immunology. Review. 13:807173-807173.
[doi:10.3389/fimmu.2022.807173]
Sanchez-Trincado JL, Pelaez-Prestel HF, Lafuente EM, Reche PA (2022).
Human Oral Epithelial Cells Suppress T Cell Function via Prostaglandin E2 Secretion.
Frontiers in immunology. Article. 12:740613-740613.
[doi:10.3389/fimmu.2021.740613]
Russo G, Di Salvatore V, Sgroi G, Parasiliti Palumbo GA, Reche PA, Pappalardo F (2022).
A multi-step and multi-scale bioinformatic protocol to investigate potential SARS-CoV-2 vaccine targets.
BRIEFINGS IN BIOINFORMATICS. Article. 23(1).
[doi:10.1093/bib/bbab403]
2021
Guo F, Estévez-Vázquez O, Benedé-Ubieto R, Maya-Miles D, Zheng K, Gallego-Durán R, Rojas Á, Ampuero J, Romero-Gómez M, Philip K, Egbuniwe IU, Chen C, Simon J, Delgado TC, Martínez-Chantar ML, Sun J, Reissing J, Bruns T, Lamas-Paz A, Moral MGD, Woitok MM, Vaquero J, Regueiro JR, Liedtke C, Trautwein C, Bañares R, Cubero FJ, Nevzorova YA (2021).
A Shortcut from Metabolic-Associated Fatty Liver Disease (MAFLD) to Hepatocellular Carcinoma (HCC): c-MYC a Promising Target for Preventative Strategies and Individualized Therapy.
Cancers. Article. 14(1).
[doi:10.3390/cancers14010192]
Chen C, Wu H, Ye H, Tortajada A, Rodríguez-Perales S, Torres-Ruiz R, Vidal A, Peligros MI, Reissing J, Bruns T, Mohamed MR, Zheng K, Lujambio A, Iraburu MJ, Colyn L, Latasa MU, Arechederra M, Fernández-Barrena MG, Berasain C, Vaquero J, Bañares R, Nelson LJ, Trautwein C, Davis RJ, Martinez-Naves E, Nevzorova YA, Villanueva A, Avila MA, Cubero FJ (2021).
Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease.
Cancers. Article. 14(1).
[doi:10.3390/cancers14010078]
Freixer, G, Zekri-Nechar, K, Zamorano-Leon, JJ, Hugo-Martinez, C, Butta, NV, Monzon, E, Recio, MJ, Giner, M, Lopez-Farre, A (2021).
Pro-apoptotic properties and mitochondrial functionality in platelet-like-particles generated from low Aspirin-incubated Meg-01 cells
Platelets. Article. 32(8):1063-1072.
[doi:10.1080/09537104.2020.1839637]
Atallah E, Freixo C, Alvarez-Alvarez I, Cubero FJ, Gerbes AL, Kullak-Ublick GA, Aithal GP (2021).
Biomarkers of idiosyncratic drug-induced liver injury (DILI) - a systematic review.
EXPERT OPINION ON DRUG METABOLISM & TOXICOLOGY. Article. 17(11):1327-1343.
[doi:10.1080/17425255.2021.1999410]
Garcia-Solis B, Van Den Rym A, Pérez-Caraballo JJ, Al-Ayoubi A, Alazami AM, Lorenzo L, Cubillos-Zapata C, López-Collazo E, Pérez-Martínez A, Allende LM, Markle J, Fernández-Arquero M, Sánchez-Ramón S, Recio MJ, Casanova JL, Mohammed R, Martinez-Barricarte R, Pérez de Diego R (2021).
Clinical and Immunological Features of Human BCL10 Deficiency.
Frontiers in immunology. Article. 12:786572-786572.
[doi:10.3389/fimmu.2021.786572]
Manka, P, Sydor, S, Wase, N, Best, J, Brandenburg, M, Hellbeck, A, Schanzer, J, Vilchez-Vargas, R, Link, A, Figge, A, Jahnert, A, von Arnim, U, Coombes, JD, Cubero, FJ, Kahraman, A, Kim, MS, Kalsch, J, Kinner, S, Faber, KN, Moshage, H, Gerken, G, Syn, WK, Friedman, SL, Canbay, A, Bechmann, LP (2021).
Anti-TNF alpha treatment in Crohn's disease: Impact on hepatic steatosis, gut-derived hormones and metabolic status
LIVER INTERNATIONAL. Article. 41(11):2646-2658.
[doi:10.1111/liv.15003]
Pelaez-Prestel, HF, Sanchez-Trincado, JL, Lafuente, EM, Reche, PA (2021).
Immune Tolerance in the Oral Mucosa
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 22(22).
[doi:10.3390/ijms222212149]
Martin-Cofreces, NB, Sanchez-Madrid, F, Roda-Navarro, P (2021).
Editorial: Cytoskeleton Dynamics as Master Regulator of Organelle Reorganization and Intracellular Signaling for Cell-Cell Competition.
Frontiers In Cell And Developmental Biology. Editorial Material. 9:782559-782559.
[doi:10.3389/fcell.2021.782559]
Pascual-Antón L, Cardeñes B, Sainz de la Cuesta R, González-Cortijo L, López-Cabrera M, Cabañas C, Sandoval P (2021).
Mesothelial-to-Mesenchymal Transition and Exosomes in Peritoneal Metastasis of Ovarian Cancer.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 22(21).
[doi:10.3390/ijms222111496]
Fernandez-Banares, F, Lopez-Palacios, N, Corzo, M, Arau, B, Rubio, M, Fernandez-Prieto, M, Tristan, E, Pujals, M, Farrais, S, Horta, S, Hernandez, JM, Gomez-Perosanz, M, Reche, PA, Esteve, M, Nunez, C (2021).
Activated gut-homing CD8(+) T cells for coeliac disease diagnosis on a gluten-free diet
BMC MEDICINE. Article. 19(1).
[doi:10.1186/s12916-021-02116-z]
Ras-Carmona, A, Pelaez-Prestel, HF, Lafuente, EM, Reche, PA (2021).
BCEPS: A Web Server to Predict Linear B Cell Epitopes with Enhanced Immunogenicity and Cross-Reactivity
Cells. Article. 10(10).
[doi:10.3390/cells10102744]
Estevez-Vazquez, O, Benede-Ubieto, R, Guo, FF, Gomez-Santos, B, Aspichueta, P, Reissing, J, Bruns, T, Sanz-Garcia, C, Sydor, S, Bechmann, LP, Maranillo, E, Sanudo, JR, Vazquez, MT, Lamas-Paz, A, Moran, L, Mazariegos, MS, Ciudin, A, Pericas, JM, Peligros, MI, Vaquero, J, Martinez-Naves, E, Liedtke, C, Regueiro, JR, Trautwein, C, Banares, R, Cubero, FJ, Nevzorova, YA (2021).
Fat: Quality, or Quantity? What Matters Most for the Progression of Metabolic Associated Fatty Liver Disease (MAFLD)
Biomedicines. Article. 9(10).
[doi:10.3390/biomedicines9101289]
Valle-Noguera A, Ochoa-Ramos A, Gomez-Sánchez MJ, Cruz-Adalia A (2021).
Type 3 Innate Lymphoid Cells as Regulators of the Host-Pathogen Interaction.
Frontiers in immunology. Article. 12:748851-748851.
[doi:10.3389/fimmu.2021.748851]
Cardeñes B, Clares I, Toribio V, Pascual L, López-Martín S, Torres-Gomez A, Sainz de la Cuesta R, Lafuente EM, López-Cabrera M, Yáñez-Mó M, Cabañas C (2021).
Cellular Integrin a5ß1 and Exosomal ADAM17 Mediate the Binding and Uptake of Exosomes Produced by Colorectal Carcinoma Cells.
INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Article. 22(18).
[doi:10.3390/ijms22189938]
Gomez-Perosanz, M, Fiyouzi, T, Fernandez-Arquero, M, Sidney, J, Sette, A, Reinherz, EL, Lafuente, EM, Reche, PA (2021).
Characterization of Conserved and Promiscuous Human Rhinovirus CD4 T Cell Epitopes
Cells. Article. 10(9).
[doi:10.3390/cells10092294]
Rawat, A, Singh, A, Dobbs, K, Pala, F, Delmonte, OM, Vignesh, P, Jindal, AK, Gupta, A, Suri, D, Kaur, A, Shandilya, JK, Sachdeva, MUS, Walia, M, Regueiro, JR, Briones, AC, Notarangelo, LD, Singh, S (2021).
Skewed TCR Alpha, but not Beta, Gene Rearrangements and Lymphoma Associated with a Pathogenic TRAC Variant
JOURNAL OF CLINICAL IMMUNOLOGY. Letter. 41(6):1395-1399.
[doi:10.1007/s10875-021-01047-x]
Gyapon-Quast F, Goicoechea de Jorge E, Malik T, Wu N, Yu J, Chai W, Feizi T, Liu Y, Pickering MC (2021).
Defining the Glycosaminoglycan Interactions of Complement Factor H-Related Protein 5.
JOURNAL OF IMMUNOLOGY. Article. 207(2):534-541.
[doi:10.4049/jimmunol.2000072]
Arimori T, Miyazaki N, Mihara E, Takizawa M, Taniguchi Y, Cabañas C, Sekiguchi K, Takagi J (2021).
Structural mechanism of laminin recognition by integrin.
NATURE COMMUNICATIONS. Article. 12(1):4012-4012.
[doi:10.1038/s41467-021-24184-8]
Mallis, RJ, Duke-Cohan, JS, Das, DK, Akitsu, A, Luoma, AM, Banik, D, Stephens, HM, Tetteh, PW, Castro, CD, Krahnke, S, Hussey, RE, Lawney, B, Brazin, KN, Reche, PA, Hwang, W, Adams, EJ, Lang, MJ, Reinherz, EL (2021).
Molecular design of the gamma delta T cell receptor ectodomain encodes biologically fit ligand recognition in the absence of mechanosensing
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Article. 118(26).
[doi:10.1073/pnas.2023050118]
Garcillan, B, Fuentes, P, Marin, AV, Megino, RF, Chacon-Arguedas, D, Mazariegos, MS, Jimenez-Reinoso, A, Munoz-Ruiz, M, Laborda, RG, Cardenas, PP, Fernandez-Malave, E, Toribio, ML, Regueiro, JR (2021).
CD3G or CD3D Knockdown in Mature, but Not Immature, T Lymphocytes Similarly Cripples the Human TCR alpha beta Complex
Frontiers In Cell And Developmental Biology. Article. 9.
[doi:10.3389/fcell.2021.608490]
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Evaluation of Polysaccharide Typhim Vi Antibody Response as a predictor of Humoral Immunodeficiency in Haematological Malignancies.
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2019
Cubero, FJ (2019).
Staging NAFLD: Diagnostic and Therapeutic Value of TAM Signaling.
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MOLECULAR IMMUNOLOGY. Article. 114:123-132.
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Mitogen-Activated Protein Kinases (MAPKs) and Cholangiocarcinoma: The Missing Link
Cells. Review. 8(10).
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Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis
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Human Oral Epithelial Cells Impair Bacteria-Mediated Maturation of Dendritic Cells and Render T Cells Unresponsive to Stimulation
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Adiponectin accounts for gender differences in hepatocellular carcinoma incidence
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Double-strand break repair through homologous recombination in autosomal-recessive BCL10 deficiency
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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and-22 Production and Promotes Intestinal Barrier Integrity
Immunity. Article. 50(2):446.
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Cubero, FJ, Woitok, MM, Zoubek, ME, de Bruin, A, Hatting, M, Trautwein, C (2019).
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Mannaerts, I, Thoen, LFR, Eysackers, N, Cubero, FJ, Leite, SB, Coldham, I, Colle, I, Trautwein, C, van Grunsven, LA (2019).
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CELL DEATH & DISEASE. Article. 10.
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Extreme Phenotypes With Identical Mutations: Two Patients With Same Non-sense NHEJ1 Homozygous Mutation
Frontiers in immunology. Article. 9:2959-2959.
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NUCLEUS. Review. 10(1):42-47.
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Lopez-Lera, A, Corvillo, F, Nozal, P, Regueiro, JR, Sanchez-Corral, P, Lopez-Trascasa, M (2019).
Complement as a diagnostic tool in immunopathology
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. Review. 85:86-97.
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2018
Lamas-Paz, A, Hao, FJ, Nelson, LJ, Vazquez, MT, Canals, S, Gómez Del Moral M, Martinez-Naves, E, Nevzorova, YA, Cubero, FJ (2018).
Alcoholic liver disease: Utility of animal models.
WORLD JOURNAL OF GASTROENTEROLOGY. Review. 24(45):5063-5075.
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Macias-Rodriguez, RU, Ruiz-Margain, A, Cantu-Brito, C, Flores-Silva DF, Garcia-Flores, OR, Cubero, FJ, Larrieta-Carrasco, E, Torre, A (2018).
Changes in Cerebral Hemodynamics in Patients With Cirrhosis After Liver Transplantation.
LIVER TRANSPLANTATION. Article. 24(12):1673-1679.
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Cubero, FJ, Peng, J, Liao, LJ, Su, H, Zhao, G, Zoubek, ME, Macias-Rodriguez, R, Ruiz-Margain, A, Reißing J, Zimmermann, HW, Gassler, N, Luedde, T, Liedtke, C, Hatting, M, Trautwein, C (2018).
Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis.
JOURNAL OF HEPATOLOGY. Article. 69(6):1326-1334.
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Phosphatase of Regenerating Liver-1 (PRL-1) Regulates Actin Dynamics During Immunological Synapse Assembly and T Cell Effector Function.
Frontiers in immunology. Article. 9:2655-2655.
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Brazin, KN, Mallis, RJ, Boeszoermenyi, A, Feng, Y, Yoshizawa, A, Reche, PA, Kaur, P, Bi, K, Hussey, RE, Duke-Cohan, JS, Song, L, Wagner, G, Arthanari, H, Lang, MJ, Reinherz, EL (2018).
The T Cell Antigen Receptor alpha Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations
Immunity. Article. 49(5):829-829.
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Evaluation of T cells in blood after a short gluten challenge for coeliac disease diagnosis.
DIGESTIVE AND LIVER DISEASE. Article. 50(11):1183-1188.
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Morán L, Cubero FJ (2018).
Extracellular vesicles in liver disease and beyond.
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Stephen, LA, ElMaghloob, Y, McIlwraith, MJ, Yelland, T, Castro Sanchez, Patricia, Roda-Navarro, P, Ismail, S (2018).
The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK
DEVELOPMENTAL CELL. Article. 47(1):122-122.
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MOLECULAR IMMUNOLOGY. Article. 102:42-57.
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Guo, FF, Zheng, K, Benede-Ubieto, R, Cubero, FJ, Nevzorova, YA (2018).
The Lieber-DeCarli Diet-A Flagship Model for Experimental Alcoholic Liver Disease.
ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. Review. 42(10):1828-1840.
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G9a Correlates with VLA-4 Integrin and Influences the Migration of Childhood Acute Lymphoblastic Leukemia Cells
Cancers. Article. 10(9).
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Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma
PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Article. 115(37):9282-9287.
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Expression of microRNA-155 in inflammatory cells modulates liver injury
HEPATOLOGY. Article. 68(2):691-706.
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Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8 + T Cells.
Frontiers in immunology. Review. 9:1751-1751.
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Monocyte-Derived Dendritic Cells Differentiated in the Presence of Lenalidomide Display a Semi-Mature Phenotype, Enhanced Phagocytic Capacity, and Th1 Polarization Capability.
Frontiers in immunology. Article. 9:1328-1328.
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Patients with CD3G mutations reveal a role for human CD3 gamma in T-reg diversity and suppressive function
BLOOD. Article. 131(21):2335-2344.
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New human combined immunodeficiency caused by interferon regulatory factor 4 (IRF4) deficiency inherited by uniparental isodisomy
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Human plasma C3 is essential for the development of memory B, but not T, lymphocytes
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 141(3):1151.
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KIDNEY INTERNATIONAL. Article. 93(2):470-481.
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LHigh Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. Article. 16(2):292-294.
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JOURNAL OF MOLECULAR GRAPHICS & MODELLING. Article. 78:195-205.
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CELL DEATH & DISEASE. Article. 8(10).
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ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy.
OncoImmunology. Article. 7(1).
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Ramadori P, Cubero FJ, Liedtke C, Trautwein C, Nevzorova YA (2017).
Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame.
Cancers. Article. 9(10).
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BLOOD. Article. 130(10):1205-1208.
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Interaction between Multimeric von Willebrand Factor and Complement: A; Fresh Look to the Pathophysiology of Microvascular Thrombosis
JOURNAL OF IMMUNOLOGY. Article. 199(3):1021-1040.
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Castro-Sánchez P, Ramirez-Munoz R, Lamana A, Ortiz A, González-Álvaro I, Roda-Navarro P (2017).
mRNA profilin identifies low levels of phosphatases dual-specific phosphatase-7 (DUSP7) and cell division cycle-25B (CDC25B) in patients with early arthritis
CLINICAL AND EXPERIMENTAL IMMUNOLOGY. Article. 189(1):113-119.
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Guasp P, Barnea E, González-Escribano MF, Jiménez-Reinoso A, Regueiro JR, Admon A, López de Castro JA (2017).
The Behcet's disease-associated variant of the aminopeptidase ERAP1; shapes a low-affinity HLA-B*51 peptidome by differential subpeptidome; processing
JOURNAL OF BIOLOGICAL CHEMISTRY. Article. 292(23):9680-9689.
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Ramadori P, Drescher H, Erschfeld S, Fragoulis A, Kensler TW, Wruck CJ, Cubero FJ, Trautwein C, Streetz KL, Kroy DC (2017).
Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH
Oxidative Medicine And Cellular Longevity. Article. 2017:3420286-3420286.
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Abos Gracia B, López Relaño J, Revilla A, Castro L, Villalba M, Martín Adrados B, Regueiro JR, Fernández-Malavé E, Martínez Naves E, Gómez Del Moral M (2017).
Human Invariant Natural Killer T Cells Respond to Antigen-Presenting Cells Exposed to Lipids from Olea europaea Pollen
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. Article. 173(1):12-22.
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Kuttkat N, Mohs A, Ohl K, Hooiveld G, Longerich T, Tenbrock K, Cubero FJ, Trautwein C (2017).
Hepatic overexpression of cAMP-responsive element modulator a induces a regulatory T-cell response in a murine model of chronic liver disease.
GUT. Article. 66(5):908-919.
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Zheng K, Cubero FJ, Nevzorova YA (2017).
c-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease
Genes. Review. 8(4).
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Crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from the; Gram-Positive Bacterial Pathogen A. vaginae, an Immunoevasive Factor; that Interacts with the Human C5a Anaphylatoxin
FRONTIERS IN MICROBIOLOGY. Article. 8:541-541.
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Immunobiology. Meeting Abstract. 221(10, SI):1214-1214.
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Different states of integrin LFA-1 aggregation are controlled through its association with tetraspanin CD9
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Severe congenital plasma C3 deficiency does not preclude intracellular C3 expression by immortalized T cell lines in two unrelated patients
MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):147-148.
Jimenez-Reinoso, Anais, Lopez-Lera, Alberto, Marin, Ana V. M., Lopez-Relano, Juan, Martinez-Naves, Eduardo, Rodriguez de Cordoba, Santiago, Roman-Ortiz, Elena, Lopez-Trascasa, Margarita, Regueiro, Jose R. (2015).
Differential impairment of dendritic, Band T cell differentiation in congenital primary (C3-deficient) as opposed to secondary (factor I-deficient) human plasma C3 deficiencies
MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):147-147.
Marin, Ana V. M., Jimenez-Reinosol, Anais, Juana-Lopez, Lucia, Rodriguez de Cordoba, Santiago, Regueiro, Jose R. (2015).
Altered B cell and bone marrow-derived dendritic cell phenotype in mouse models with secondary C3 deficiency
MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):158-159.
Rahman, Sunniyat, Pinto, Sheila, Hajji, Nabil, Rodriguez de Cordoba, Santiago, Goicoechea de Jorge, Elena (2015).
miRNAs as novel biomarkers of disease status in atypical haemolytic uremic syndrome
MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):172-173.
Álvarez B, Escalona Z, Uenishi H, Toki D, Revilla C, Yuste M, Del Moral MG, Alonso F, Ezquerra A, Domínguez J (2015).
Molecular and functional characterization of porcine Siglec-3/CD33 and analysis of its expression in blood and tissues
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A Novel MEK-ERK-AMPK Signaling Axis Controls Chemokine Receptor CCR7-dependent Survival in Human Mature Dendritic Cells
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EPIPOX: Immunoinformatic Characterization of the Shared T-Cell Epitome between Variola Virus and Related Pathogenic Orthopoxviruses
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Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity
JOURNAL OF CLINICAL INVESTIGATION. Article. 124(12):5239-5248.
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Subias Hidalgo, Marta, Yebenes, Hugo, Dominguez, Mercedes, Jimenez, Anais, Regueiro, J. R., Llorca, Oscar, Rodriguez de Cordoba, Santiago (2014).
Dissection of C3 functions using novel mouse monoclonal antibodies to activated human C3 fragments
MOLECULAR IMMUNOLOGY. Meeting Abstract. 61(2, SI):253-254.
Roda-Navarro P, Bastiaens PI (2014).
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The CD3 Conformational Change in the gamma delta T Cell Receptor Is Not Triggered by Antigens but Can Be Enforced to Enhance Tumor Killing
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DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. Article. 44(1):206-216.
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Enrichment of the rare CD4(+) gamma delta T-cell subset in patients with atypical CD3 delta deficiency
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 133(4):1205-1208.
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2013
Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS (2013).
Paneth cells as a site of origin for intestinal inflammation
Nature. Article. 503(7475):272-272.
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RIAM (Rap1-interacting adaptor molecule) regulates complement-dependent phagocytosis
CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 70(13):2395-2410.
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N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8(+) T cell memory but not to effector differentiation
JOURNAL OF EXPERIMENTAL MEDICINE. Article. 210(7):1463-1479.
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Abós-Gracia B, del Moral MG, López-Relaño J, Viana-Huete V, Castro L, Villalba M, Martínez-Naves E (2013).
Olea europaea pollen lipids activate invariant natural killer T cells by upregulating CD1d expression on dendritic cells
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INTEGRATIVE BIOLOGY. Review. 5(2):300-311.
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Gilsanz A, Sánchez-Martín L, Gutiérrez-López MD, Ovalle S, Machado-Pineda Y, Reyes R, Swart GW, Figdor CG, Lafuente EM, Cabañas C (2013).
ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9
CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 70(3):475-493.
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Munoz-Ruiz, Miguel, Perez-Flores, Veronica, Garcillan, Beatriz, Guardo, Alberto C., Mazariegos, Marina S., Takada, Hidetoshi, Allende, Luis M., Kilic, Sara S., Sanal, Ozden, Roifman, Chaim M., Lopez-Granados, Eduardo, Recio, Maria J., Martinez-Naves, Eduardo, Fernandez-Malave, Edgar, Regueiro, Jose R. (2013).
Human CD3 gamma, but not CD3 delta, haploinsufficiency differentially impairs gamma delta versus alpha beta surface TCR expression
BMC IMMUNOLOGY. Article. 14(3):3-3.
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Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells
CLINICAL & DEVELOPMENTAL IMMUNOLOGY. Article. 2013:362163-362163.
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Molero-Abraham M, Lafuente EM, Flower DR, Reche PA (2013).
Selection of Conserved Epitopes from Hepatitis C Virus for Pan-Populational Stimulation of T-Cell Responses
CLINICAL & DEVELOPMENTAL IMMUNOLOGY. Article. 2013:601943-601943.
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Cd3 haploinsufficiencies reveal the existence of differential CD3 chain functions in murine alpha beta T cell development, phenotype and function.
Proceedings Of The 15th Meeting Of The European Society Immunodeficiencies (esid). Capítulo de un Libro. 105-110.
2012
García-Zaragoza E, Pérez-Tavarez R, Ballester A, Lafarga V, Jiménez-Reinoso A, Ramírez A, Murillas R, Gallego MI (2012).
Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland
DEVELOPMENTAL BIOLOGY. Article. 372(1):28-44.
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NON-HOMOLOGOUS END-JOINING DEFECTS WITHIN DNA-REPAIRING DEFECTS: WIDE CLINICAL SPECTRUM AND OUTCOME IN A TERTIARY SINGLE HOSPITAL
JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):313-314.
Garcillan, B., Mazariegos, M. S., Fish, P., Munoz-Ruiz, M., Gil, J., Lopez-Granados, E., Recio, M. J., Regueiro, J. (2012).
CHARACTERIZATION OF Gamma Delta T LYMPHOCYTES IN TAB(-)T Gamma Delta plus B plus NK plus SCID DUE TO LEAKY CD3D MUTATIONS
JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):308-308.
Recio, M. J., Couso, J., Busto, E., Allende, L. M., van Montfrans, J., Lefranc, G., Pablos, J. L., Regueiro, J. R. (2012).
THE CD3G P.V131F MUTATION IN IMMUNODEFICIENCY AND AUTOIMMUNITY
JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):320-321.
Munoz-Ruiz, M., Mazariegos, M. S., Garcillan, B., Delgado, M., Fernandez-Malave, E., Regueiro, J. R. (2012).
Selective roles of CD3 chains in T cell development, TCR expression and T cell effector functions revealed by CD3 haploinsufficiencies
Immunology. Meeting Abstract. 137(1, SI):10-10.
Mazariegos, M. S., Garcillan, B., Munoz-Ruiz, M., Regueiro, J. R. (2012).
Physiopathology of TCR/CD3: genomic induction in CD3gamma deficient cells
Immunology. Meeting Abstract. 137(1, SI):377-378.
Garcillan, B., Mazariegos, M. S., Fish, P., Munoz-Ruiz, M., Gil, J., Lopez-Granados, E., Regueiro, J. R. (2012).
Study of gamma delta T cells in a Tab-Tgd plus B plus NK plus SCID due to CD3D mutations
Immunology. Meeting Abstract. 137(1, SI):569-569.
Munoz-Ruiz, M., Mazariegos, M. S., Garcillan, B., Delgado, M., Fernandez-Malave, E., Regueiro, J. R. (2012).
CD3 HAPLOINSUFFICIENCIES REVEAL THE EXISTENCE OF DIFFERENTIAL CD3 CHAIN FUNCTIONS IN MURINE.. T CELL DEVELOPMENT, PHENOTYPE AND FUNCTION EX AND IN VIVO
JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):19-20.
Diez-Rivero, Carmen M., Reche, Pedro A. (2012).
CD8 T Cell Epitope Distribution in Viruses Reveals Patterns of Protein Biosynthesis
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AUTOIMMUNITY REVIEWS. Review. 11(1):40-47.
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Marcus, Nufar, Takada, Hidetoshi, Law, Jason, Cowan, Morton J., Gil, Juana, Regueiro, Jose R., Lopez de Sabando, Diego Plaza, Lopez-Granados, Eduardo, Dalal, Jignesh, Friedrich, Wilhelm, Manfred, Hoenig, Hanson, Imelda Celine, Grunebaum, Eyal, Shearer, William T., Roifman, Chaim M. (2011).
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The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9
CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 68(19):3275-3292.
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A leaky mutation in CD3D differentially affects alpha beta and gamma delta T cells and leads to a T alpha beta T-gamma delta+B+NK+ human SCID
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