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Inmunobiología Linfocitaria

Publicaciones

2025

Arroyo-Ródenas, J, Falgas, A, Díez-Alonso, L, Martinez-Moreno, A, Roca-Ho, H, Gil-Etayo, FJ, Pérez-Pons, A, Aguilar-Sopeña, O, Velasco-Sidro, M, Gómez-Rosel, M, Jiménez-Matías, B, Muñoz-Sánchez, G, Pacheco, Y, Bravo-Martín, C, Ramírez-Fernández, A, Jiménez-Reinoso, A, González-Navarro, EA, Juan, ME, Orfao, A, Blanco, B, Roda-Navarro, P, Bueno, C, Menéndez, P, Alvarez-Vallina, L (2025).

CD22 CAR-T cells secreting CD19 T-cell engagers for improved control of B-cell acute lymphoblastic leukemia progression

Journal For Immunotherapy Of Cancer. Article. 13(4).
[doi:10.1136/jitc-2024-009048]
García, AG, Aporta, MF, Palma, GV, Trujillo, AG, Castillo-González, R, Lozano, DC, Perdiguero, AM, Velasco, RM, Castro, MC, Benito, ED, Torres-Ruiz, R, Rodriguez-Perales, S, Dehairs, J, Swinnen, JV, Garcia-Cañaveras, JC, Lahoz, A, Quirós, SM, del Pozo-Rojas, C, Rioja, CL, Monroy, F, Herráez-Aguilar, D, Riaño, MA, Peralto, JLR, Lobo, VJSA (2025).

Targeting ELOVL6 to disrupt c-MYC driven lipid metabolism in pancreatic cancer enhances chemosensitivity

NATURE COMMUNICATIONS. Article. 16(1).
[doi:10.1038/s41467-025-56894-8]
Gomez-Bris, R, Rodriguez-Rodriguez, P, Ortega-Zapero, M, Ruvira, S, Castillo-Gonzalez, R, Fernandez-Acenero, MJ, Cruz-Adalia, A, Saez, A, Arribas, SM, Gonzalez-Granado, JM (2025).

Segmental Regulation of Intestinal Motility by Colitis and the Adaptive Immune System in the Mouse Ileum and Colon

AMERICAN JOURNAL OF PATHOLOGY. Article. 195(2):204-220.
[doi:10.1016/j.ajpath.2024.10.020]

2024

Vojdani, A, Yaqinuddin, A, Beretta, A, Reche, PA (2024).

Editorial: Cross-reactive immunity and COVID-19

Frontiers in immunology. Editorial Material. 15:1509379-1509379.
[doi:10.3389/fimmu.2024.1509379]
Jiménez, E, Vázquez, A, González, S, Sacedón, R, Fernández-Sevilla, LM, Varas, A, Subiza, JL, Valencia, J, Vicente, A (2024).

Mucosal Bacterial Immunotherapy Attenuates the Development of Experimental Colitis by Reducing Inflammation Through the Regulation of Myeloid Cells

International Journal Of Molecular Sciences. Article. 25(24).
[doi:10.3390/ijms252413629]
Pelaez-Prestel, HF, Gonzalez-Martin, F, Ras-Carmona, A, Rocha, A, Cabañas, C, Lafuente, EM, Reche, PA (2024).

Oral squamous cell carcinomas drive monocytes into immunosuppressive CD25+CD163+CD206+macrophages

ORAL ONCOLOGY. Article. 159:107078-107078.
[doi:10.1016/j.oraloncology.2024.107078]
Vaquero-Yuste, C, Juarez, I, Molina-Alejandre, M, Molanes-López, EM, Gutiérrez-Calvo, A, López-García, A, Lasa, I, Gómez, R, Arnaiz-Villena, A, Martín-Villa, JM (2024).

HLA-G high-expressor 3'UTR markers are linked to gastric cancer development and survival

CANCER IMMUNOLOGY IMMUNOTHERAPY. Article. 74(1):26-26.
[doi:10.1007/s00262-024-03771-w]
Izquierdo, M, Ruiz-Navarro, J, Baldari, CT, Roda-Navarro, P (2024).

Editorial: Structure and function of the immunological and redirecting artificial synapses and their clinical implications

Frontiers in immunology. Editorial Material. 15:1497118-1497118.
[doi:10.3389/fimmu.2024.1497118]
Briones, AC, Megino, RF, Marin, AV, Chacón-Arguedas, D, García-Martinez, E, Balastegui-Martín, H, Reyburn, HT, Henrickson, SE, Rodríguez-Sainz, C, Seoane-Reula, E, Sanchez-Mateos, P, Cardenas, PP, Regueiro, JR (2024).

Nonsense CD247 mutations show dominant- negative features in T-cell receptor expression and function

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 154(4):1022-1032.
[doi:10.1016/j.jaci.2024.06.019]
Fernandez, SA, Pelaez-Prestel, HF, Ras-Carmona, A, Mozas-Gutierrez, J, Reyes-Manzanas, R, Reche, PA (2024).

Eucalyptus Essential Oil Inhibits Cell Infection by SARS-CoV-2 Spike Pseudotyped Lentivirus

Biomedicines. Article. 12(8).
[doi:10.3390/biomedicines12081885]
Gómez-Morón, A, Alegre-Gómez, S, Ramirez-Muñoz, R, Hernaiz-Esteban, A, Carrasco-Padilla, C, Scagnetti, C, Aguilar-Sopeña, O, García-Gil, M, Borroto, A, Torres-Ruiz, R, Rodriguez-Perales, S, Sánchez-Madrid, F, Martín-Cófreces, NB, Roda-Navarro, P (2024).

Human T-cell receptor triggering requires inactivation of Lim kinase-1 by Slingshot-1 phosphatase

Communications Biology. Article. 7(1):918-918.
[doi:10.1038/s42003-024-06605-8]
Fernandez, SA, Pelaez-Prestel, HF, Fiyouzi, T, Gomez-Perosanz, M, Reiné, J, Reche, PA (2024).

Tetanus-diphtheria vaccine can prime SARS-CoV-2 cross-reactive T cells

Frontiers in immunology. Article. 15:1425374-1425374.
[doi:10.3389/fimmu.2024.1425374]
Budeus, B, Alvaro-Benito, M, Crivello, P (2024).

HLA-DM and HLA-DO interplay for the peptide editing of HLA class II in healthy tissues and leukemia

BEST PRACTICE & RESEARCH CLINICAL HAEMATOLOGY. Article. 37(2):101561-101561.
[doi:10.1016/j.beha.2024.101561]
Gómez-García, AR, Fernandez-Moreira, E, García-León, X, del Moral, MG (2024).

Comparative analysis of leukemia and risk estimation in working age population between provinces of Ecuador

Medwave. Article. 24(6).
[doi:10.5867/medwave.2024.06.2903]
Ras-Carmona, A, Reche, PA (2024).

Analysis of Virus-Specific B Cell Epitopes Reveals Extensive Antigen Degradation Prior to Recognition

Cells. Article. 13(13).
[doi:10.3390/cells13131076]
Ojeda, P, Barjau, MC, Subiza, J, Moreno, A, Ojeda, I, Solano, E, Alonso, A, Caballero, R, Del Pozo, S, Gomez-Perosanz, M, Sanchez-Trincado, JL, Benito-Villalvilla, C, Angelina, A, Soria, I, Reche, PA, Palomares, O, Subiza, JL, Casanovas, M (2024).

Grass pollen allergoids conjugated with mannan for subcutaneous and sublingual immunotherapy: a dose-finding study

Frontiers in immunology. Article. 15:1431351-1431351.
[doi:10.3389/fimmu.2024.1431351]
Amóros-Pérez, B, Rivas-Pardo, B, del Moral, MG, Subiza, JL, Martínez-Naves, E (2024).

State of the Art in CAR-T Cell Therapy for Solid Tumors: Is There a Sweeter Future?

Cells. Review. 13(9).
[doi:10.3390/cells13090725]
Lamas-Paz, A, Mesquita, M, Garcia-Lacarte, M, Estévez-Vázquez, O, Benedé-Ubieto, R, Gutierrez, AH, Wu, HH, Lasalle, HL, Vaquero, J, Bañares, R, Martínez-Naves, E, Roa, S, Nevzorova, YA, Jorquera, G, Cubero, FJ (2024).

Fecal microbiota transplantation from female donors restores gut permeability and reduces liver injury and inflammation in middle-aged male mice exposed to alcohol

Frontiers in nutrition. Article. 11:1393014-1393014.
[doi:10.3389/fnut.2024.1393014]
Materna M, Delmonte OM, Bosticardo M, Momenilandi M, Conrey PE, Charmeteau-De Muylder B, Bravetti C, Bellworthy R, Cederholm A, Staels F, Ganoza CA, Darko S, Sayed S, Le Floc'h C, Ogishi M, Rinchai D, Guenoun A, Bolze A, Khan T, Gervais A, Krüger R, Völler M, Palterer B, Sadeghi-Shabestari M, Langlois de Septenville A, Schramm CA, Shah S, Tello-Cajiao JJ, Pala F, Amini K, Campos JS, Lima NS, Eriksson D, Lévy R, Seeleuthner Y, Jyonouchi S, Ata M, Al Ali F, Stittrich A, Deswarte C, Pereira A, Mégret J, Le Voyer T, Bastard P, Berteloot L, Dussiot M, Vladikine N, Cardenas PP, Jouanguy E, Alqahtani M, Hasan A, Thanaraj TA, Rosain J, Al Qureshah F, Sabato V, Alyanakian MA, Leruez-Ville M, Rozenberg F, Haddad E, Regueiro JR, Toribio ML, Kelsen JR, Salehi M, Nasiri S, Torabizadeh M, Rokni-Zadeh H, Changi-Ashtiani M, Vatandoost N, Moravej H, Akrami SM, Mazloomrezaei M, Cobat A, Meyts I, Toyofuku E, Nishimura M, Moriya K, Mizukami T, Imai K, Abel L, Malissen B, Al-Mulla F, Alkuraya FS, Parvaneh N, von Bernuth H, Beetz C, Davi F, Douek DC, Cheynier R, Langlais D, Landegren N, Marr N, Morio T, Shahrooei M, Schrijvers R, Henrickson SE, Luche H, Notarangelo LD, Casanova JL, Béziat V (2024).

The immunopathological landscape of human pre-TCRa deficiency: From rare to common variants.

Science. Article. 383(6686).
[doi:10.1126/science.adh4059]
Clares-Pedrero, I, Rocha-Mulero, A, Palma-Cobo, M, Cardeñes, B, Yáñez-Mó, M, Cabañas, C (2024).

Molecular Determinants Involved in the Docking and Uptake of Tumor-Derived Extracellular Vesicles: Implications in Cancer

International Journal Of Molecular Sciences. Review. 25(6).
[doi:10.3390/ijms25063449]
Díez-Alonso, L, Falgas, A, Arroyo-Ródenas, J, Romencín, PA, Martínez, A, Gomez-Rosel, M, Blanco, B, Jiménez-Reinoso, A, Mayado, A, Perez-Pons, A, Aguilar-Sopeña, O, Ramirez-Fernández, A, Segura-Tudela, A, Pérez-Amill, L, Tapia-Galisteo, A, Domínguez-Alonso, C, Rubio-Peréz, L, Jara, M, Solé, F, Hangiu, O, Almagro, L, Albitre, A, Penela, P, Sanz, L, Anguita, E, Valeri, A, García-Ortiz, A, Río, P, Juan, ME, Martínez-López, J, Roda-Navarro, P, Martín-Antonio, B, Orfao, A, Menéndez, P, Bueno, C, alvarez-Vallina, L (2024).

Engineered T cells secreting anti-BCMA T cell engagers control multiple myeloma and promote immune memory in vivo

SCIENCE TRANSLATIONAL MEDICINE. Article. 16(734).
[doi:10.1126/scitranslmed.adg7962]
Terri, M, Sandoval, P, Bontempi, G, Montaldo, C, Tomero-Sanz, H, de Turris, V, Trionfetti, F, Pascual-Anton, L, Clares-Pedrero, I, Battistelli, C, Valente, S, Zwergel, C, Mai, ATEL, Rosanò, L, del Pozo, MA, Sanchez-Alvarez, M, Cabanas, C, Tripodi, M, López-Cabrera, M, Strippoli, R (2024).

HDAC1/2 control mesothelium/ovarian cancer adhesive interactions impacting on Talin-1-a5ß1-integrin-mediated actin cytoskeleton and extracellular matrix protein remodeling

JOURNAL OF EXPERIMENTAL & CLINICAL CANCER RESEARCH. Article. 43(1):27-27.
[doi:10.1186/s13046-023-02930-8]

2023

Valle-Noguera, A, Sancho-Temiño, L, Aragone, J, Castillo-González, R, Villa-Gómez, C, Gomez-Sánchez, MJ, Ochoa-Ramos, A, Yagüe-Fernández, P, Palacios, BS, Zorita, V, Raposo-Ponce, B, González-Granado, JM, Aragonés, J, Cruz-Adalia, A (2023).

IL-18-induced HIF-1a in ILC3s ameliorates the inflammation of C. rodentium-induced colitis

CELL REPORTS. Article. 42(12).
[doi:10.1016/j.celrep.2023.113508]
Muñoz-Ruiz M, Llorian M, D'Antuono R, Pavlova A, Mavrigiannaki AM, McKenzie D, García-Cassani B, Iannitto ML, Wu Y, Dart R, Davies D, Jamal-Hanjani M, Jandke A, Ushakov DS, Hayday AC (2023).

IFN-?-dependent interactions between tissue-intrinsic ?d T cells and tissue-infiltrating CD8 T cells limit allergic contact dermatitis.

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 152(6):1520-1540.
[doi:10.1016/j.jaci.2023.07.015]
Molina, E, García-Gutiérrez, L, Junco, V, Perez-Olivares, M, de Yébenes, VG, Blanco, R, Quevedo, L, Acosta, JC, Marín, AV, Ulgiati, D, Merino, R, Delgado, MD, Varela, I, Regueiro, JR, de Alborán, IM, Ramiro, AR, León, J (2023).

MYC directly transactivates CR2/CD21, the receptor of the Epstein-Barr virus, enhancing the viral infection of Burkitt lymphoma cells

ONCOGENE. Article. 42(45):3358-3370.
[doi:10.1038/s41388-023-02846-9]
de Lope-Planelles, A, González-Novo, R, Madrazo, E, Peralta-Carrero, G, Rodríguez, MPC, Zamora-Carreras, H, Torrano, V, López-Menéndez, H, Roda-Navarro, P, Monroy, F, Redondo-Muñoz, J (2023).

Mechanical stress confers nuclear and functional changes in derived leukemia cells from persistent confined migration

CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 80(11).
[doi:10.1007/s00018-023-04968-5]
Fuertes, T, Alvarez-Corrales, E, Gómez-Escolar, C, Ubieto-Capella, P, Serrano-Navarro, A, de Molina, A, Méndez, J, Ramiro, AR, de Ybenes, VG (2023).

miR-28-based combination therapy impairs aggressive B cell lymphoma growth by rewiring DNA replication

CELL DEATH & DISEASE. Article. 14(10).
[doi:10.1038/s41419-023-06178-0]
García-Solís, B, van den Rym, AD, Martinez-Martínez, L, Franco, T, Pérez-Caraballo, JJ, Markle, J, Cubillos-Zapata, C, Marín, A, Recio, MJ, Regueiro, JR, Navarro-Zapata, A, Mestre-Durán, C, Ferreras, C, Cotázar, CM, Mena, R, de la Calle-fabregat, C, López-Lera, A, Arquero, MF, Pérez-Martínez, A, López-Collazo, E, Sánchez-Ramón, S, Casanova, JL, Martínez-Barricarte, R, de la Calle-martin, O, de Diego, RP (2023).

Inherited human ezrin deficiency impairs adaptive immunity

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 152(4):997.
[doi:10.1016/j.jaci.2023.05.022]
Chacon-Arguedas, D, Benito, IE, Fernández-Boraita, J, Jimenez, DJ, Tortajada, A, Marin, AV, Regueiro, JR (2023).

aß T cells and complement meet again: TCR crosstalk with surface complement regulators

Immunobiology. Meeting Abstract. 228(5):28-28.
[doi:10.1016/j.imbio.2023.152525]
Bodas-Pinedo A, Lafuente EM, Pelaez-Prestel HF, Ras-Carmona A, Subiza JL, Reche PA (2023).

Combining different bacteria in vaccine formulations enhances the chance for antiviral cross-reactive immunity: a detailed in silico analysis for influenza A virus.

Frontiers in immunology. Article. 14:1235053-1235053.
[doi:10.3389/fimmu.2023.1235053]
Zheng, K, Hao, FJ, Medrano-Garcia, S, Chen, CB, Guo, FF, Morán-Blanco, L, Rodríguez-Perales, S, Torres-Ruiz, R, Peligros, MI, Vaquero, J, Bañares, R, del Moral, MG, Regueiro, JR, Martínez-Naves, E, Mohamed, MR, Gallego-Durán, R, Maya, D, Ampuero, J, Romero-Gómez, M, Gilbert-Ramos, A, Guixé-Muntet, S, Fernández-Iglesias, A, Gracia-Sancho, J, Coll, M, Graupera, I, Ginès, P, Ciudin, A, Rivera-Esteban, J, Pericàs, JM, Frutos, MD, Molina, BR, Herranz, JM, Avila, MA, Nevzorova, YA, Fernández-Malavé, E, Cubero, FJ (2023).

Neuroblastoma RAS viral oncogene homolog (N-RAS) deficiency aggravates liver injury and fibrosis

CELL DEATH & DISEASE. Article. 14(8).
[doi:10.1038/s41419-023-06029-y]
Vera-Zambrano, A, Lago-Docampo, M, Gallego, N, Franco-Gonzalez, JF, Morales-Cano, D, Cruz-Utrilla, A, Villegas-Esguevillas, M, Fernández-Malavé, E, Escribano-Subías, P, Tenorio-Castaño, JA, Perez-Vizcaino, F, Valverde, D, González, T, Cogolludo, A (2023).

Novel Loss-of-Function KCNA5 Variants in Pulmonary Arterial Hypertension

AMERICAN JOURNAL OF RESPIRATORY CELL AND MOLECULAR BIOLOGY. Article. 69(2):147-158.
[doi:10.1165/rcmb.2022-0245OC]
Martín-Adrados, B, Wculek, SK, Fernández-Bravo, S, Torres-Ruiz, R, Valle-Noguera, A, Gomez-Sánchez, MJ, Hernández-Walias, JC, Ferreira, FM, Corraliza, AM, Sancho, D, Esteban, V, Rodriguez-Perales, S, Cruz-Adalia, A, Nakaya, HI, Salas, A, Bernardo, D, Campos-Martín, Y, Martínez-Zamorano, E, Muñoz-López, D, del Moral, MG, Cubero, FJ, Blumberg, RS, Martínez-Naves, E (2023).

Expression of HMGCS2 in intestinal epithelial cells is downregulated in inflammatory bowel disease associated with endoplasmic reticulum stress

Frontiers in immunology. Article. 14.
[doi:10.3389/fimmu.2023.1185517]
Natalini, A, Simonetti, S, Favaretto, G, Lucantonio, L, Peruzzi, G, Munoz-Ruiz, M, Kelly, G, Contino, AM, Sbrocchi, R, Battella, S, Capone, S, Folgori, A, Nicosia, A, Santoni, A, Hayday, AC, Di Rosa, F (2023).

Improved memory CD8 T cell response to delayed vaccine boost is associated with a distinct molecular signature (vol 14, 1043631, 2023)

Frontiers in immunology. Correction. 14.
[doi:10.3389/fimmu.2023.1199754]
Fiyouzi, T, Pelaez-Prestel, HF, Reyes-Manzanas, R, Lafuente, EM, Reche, PA (2023).

Students' Perceptions of Their Student-Operated Restaurant Experience: A Qualitative Study

International Journal Of Molecular Sciences. Review. 24(9).
[doi:10.3390/ijms24097797]
Sanz-Garcia, Carlos, Nevzorova, Yulia A, Martinez-Naves, Eduardo, Cubero, Francisco Javier, Hionides-Gutierrez, Alejandro, Sanudo, Jose Ramon, Enrich, Carlos, Rentero, Carles, Sancho-Bru, Pau, Macias-Rodriguez, Ricardo U, Ruiz-Margain, Astrid, Kershenobich-Stalnikowitz, David, Vargas, Nestor R, Munoz, Alberto E, Nakaya, Helder I (2023).

Novel therapeutic avenues for the study of chronic liver disease and regeneration: The foundation of the Iberoamerican Consortium for the study of liver Cirrhosis.

GASTROENTEROLOGIA Y HEPATOLOGIA. Article. 46(4):322-328.
[doi:10.1016/j.gastrohep.2022.05.012]
Gómez-Morón A, Requena S, Roda-Navarro P, Martín-Cófreces NB (2023).

Activation kinetics of regulatory molecules during immunological synapse in T cells.

METHOD CELL BIOL. Article. 178:149-171.
[doi:10.1016/bs.mcb.2022.10.014]
Saksena NK, Reche PA, Bonam SR, Mancini N (2023).

Editorial: Innate immune responses to SARS-CoV-2 in infected and vaccinated individuals.

Frontiers in immunology. Editorial Material. 14:1141405-1141405.
[doi:10.3389/fimmu.2023.1141405]
Pérez-Flores I, Juarez I, Aiffil Meneses AS, Lopez-Gomez A, Romero NC, Rodriguez-Cubillo B, Moreno de la Higuera MA, Peix-Jiménez B, Gonzalez-Garcia R, Baos-Muñoz E, Vilela AA, Gómez del Moral M, Martínez-Naves E, Sanchez-Fructuoso AI (2023).

Role of mTOR inhibitor in the cellular and humoral immune response to a booster dose of SARS-CoV-2 mRNA-1273 vaccine in kidney transplant recipients.

Frontiers in immunology. Article. 14:1111569-1111569.
[doi:10.3389/fimmu.2023.1111569]
Pelaez-Prestel HF, Fernandez SA, Ballesteros-Sanabria L, Reche PA (2023).

Prediction of TAP Transport of Peptides with Variable Length Using TAPREG.

Methods in molecular biology (Clifton, N.J.). Article. 2673:227-235.
[doi:10.1007/978-1-0716-3239-0_16]
Toribio, ML, González-García, S (2023).

Notch Partners in the Long Journey of T-ALL Pathogenesis

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 24(2).
[doi:10.3390/ijms24021383]
Carrasco-Padilla C, Aguilar-Sopeña O, Gómez-Morón A, Alegre-Gómez S, Sánchez-Madrid F, Martín-Cófreces NB, Roda-Navarro P (2023).

T cell activation and effector function in the human Jurkat T cell model.

METHOD CELL BIOL. Article. 178:25-41.
[doi:10.1016/bs.mcb.2022.09.012]
Ballesteros-Sanabria L, Pelaez-Prestel HF, Reche PA, Lafuente EM (2023).

EPIPOX: A Resource Facilitating Epitope-Vaccine Design Against Human Pathogenic Orthopoxviruses.

Methods in molecular biology (Clifton, N.J.). Article. 2673:175-185.
[doi:10.1007/978-1-0716-3239-0_12]
Fiyouzi T, Reche PA (2023).

Vaccine Design: An Introduction.

Methods in molecular biology (Clifton, N.J.). Article. 2673:1-14.
[doi:10.1007/978-1-0716-3239-0_1]

2022

Carrasco-Padilla, C, Hernaiz-Esteban, A, alvarez-Vallina, L, Aguilar-Sopena, O, Roda-Navarro, P (2022).

Bispecific Antibody Format and the Organization of Immunological Synapses in T Cell-Redirecting Strategies for Cancer Immunotherapy.

Pharmaceutics. Review. 15(1).
[doi:10.3390/pharmaceutics15010132]
Cook ECL, Redondo-Urzainqui A, Iborra S (2022).

Obesity can turn a therapy into an antitherapy in atopic dermatitis.

ALLERGY. News Item. 77(11):3473-3475.
[doi:10.1111/all.15482]
Caravaca-Fontán F, Lucientes L, Serra N, Cavero T, Rodado R, Ramos N, Gonzalez F, Shabaka A, Cabello V, Huerta A, Pampa-Saico S, Gutiérrez E, Quintana LF, López-Rubio ME, Draibe J, Titos JA, Fernández-Juárez G, de Jorge EG, Praga M (2022).

C3 glomerulopathy associated with monoclonal gammopathy: impact of chronic histologic lesions and beneficial effects of clone-targeted therapies.

NEPHROLOGY DIALYSIS TRANSPLANTATION. Article. 37(11):2128-2137.
[doi:10.1093/ndt/gfab302]
Marin, AV, Jimenez-Reinoso, A, Mazariegos, MS, Roman-Ortiz, E, Regueiro, JR (2022).

T-cell receptor signaling in Schimke immuno-osseous dysplasia is SMARCAL1-independent.

Frontiers in immunology. Article. 13:979722-979722.
[doi:10.3389/fimmu.2022.979722]
Castillo-Gonzalez, R, Valle-Noguera, A, Gomez-Sanchez, MJ, Xia, P, Cruz-Adalia, A (2022).

Innate lymphoid cells type 3 in cancer.

Frontiers in immunology. Review. 13:1033252-1033252.
[doi:10.3389/fimmu.2022.1033252]
Torres-Gomez, A, Fiyouzi, T, Guerra-Espinosa, C, Cardenes, B, Clares, I, Toribio, V, Reche, PA, Cabanas, C, Lafuente, EM (2022).

Expression of the phagocytic receptors alpha(M)beta(2) and alpha(X)beta(2) is controlled by RIAM, VASP and Vinculin in neutrophil-differentiated HL-60 cells

Frontiers in immunology. Article. 13:951280-951280.
[doi:10.3389/fimmu.2022.951280]
Garcillán B, Megino RF, Herrero-Alonso M, Guardo AC, Perez-Flores V, Juraske C, Idstein V, Martin-Fernandez JM, Geisler C, Schamel WWA, Marin AV, Regueiro JR (2022).

The role of the different CD3? domains in TCR expression and signaling.

Frontiers in immunology. Article. 13:978658-978658.
[doi:10.3389/fimmu.2022.978658]
Ras-Carmona A, Lehmann AA, Lehmann PV, Reche PA (2022).

Prediction of B cell epitopes in proteins using a novel sequence similarity-based method.

SCIENTIFIC REPORTS. Article. 12(1):13739-13739.
[doi:10.1038/s41598-022-18021-1]
Medrano-Garcia S, Morales-Cano D, Barreira B, Vera-Zambrano A, Kumar R, Kosanovic D, Schermuly RT, Graham BB, Perez-Vizcaino F, Mathie A, Savai R, Pullamseti S, Butrous G, Fernández-Malavé E, Cogolludo A (2022).

HIV and Schistosoma Co-Exposure Leads to Exacerbated Pulmonary Endothelial Remodeling and Dysfunction Associated with Altered Cytokine Landscape.

Cells. Article. 11(15).
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Activation of the Unfolded Protein Response (UPR) Is Associated with Cholangiocellular Injury, Fibrosis and Carcinogenesis in an Experimental Model of Fibropolycystic Liver Disease.

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Cellular Integrin a5ß1 and Exosomal ADAM17 Mediate the Binding and Uptake of Exosomes Produced by Colorectal Carcinoma Cells.

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Skewed TCR Alpha, but not Beta, Gene Rearrangements and Lymphoma Associated with a Pathogenic TRAC Variant

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CD3G or CD3D Knockdown in Mature, but Not Immature, T Lymphocytes Similarly Cripples the Human TCR alpha beta Complex

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Transcriptomic Profiling of the Liver Sinusoidal Endothelium during Cirrhosis Reveals Stage-Specific Secretory Signature

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An Experimental DUAL Model of Advanced Liver Damage

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Liver fibrosis in patients with metabolic associated fatty liver disease is a risk factor for adverse outcomes in COVID-19.

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Gender and gut microbiota composition determine hepatic bile acid, metabolic and inflammatory response to a single fast-food meal in healthy adults

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Intestinal Epithelial Cell-Derived Extracellular Vesicles Modulate Hepatic Injury via the Gut-Liver Axis During Acute Alcohol Injury

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Resistance to Experimental Visceral Leishmaniasis in Mice Infected With Leishmania infantum Requires Batf3.

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JOURNAL OF HEPATOLOGY. Review. 73(2):423-440.
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Pilot Multi-Omic Analysis of Human Bile from Benign and Malignant Biliary Strictures: A Machine-Learning Approach

Cancers. Article. 12(6).
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Loss of c-Jun N-terminal Kinase 1 and 2 Function in Liver Epithelial Cells Triggers Biliary Hyperproliferation Resembling Cholangiocarcinoma.

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Lipid-encapsulated siRNA for hepatocyte-directed treatment of advanced liver disease

CELL DEATH & DISEASE. Article. 11(5).
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RIAM-VASP Module Relays Integrin Complement Receptors in Outside-In Signaling Driving Particle Engulfment

Cells. Article. 9(5).
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Phagocytic Integrins: Activation and Signaling.

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Multiple particle tracking analysis in isolated nuclei reveals the mechanical phenotype of leukemia cells.

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Effect of Pharmacological Inhibition of the Catalytic Activity of Phosphatases of Regenerating Liver in Early T Cell Receptor Signaling Dynamics and IL-2 Production

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Subcutaneous Immunization of Leishmania HSP70-II Null Mutant Line Reduces the Severity of the Experimental Visceral Leishmaniasis in BALB/c Mice

Vaccines. Article. 8(1).
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Reclassifying Hepatic Cell Death during Liver Damage: Ferroptosis-A Novel Form of Non-Apoptotic Cell Death?

INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES. Review. 21(5).
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Altered Microbiota Diversity and Bile Acid Signaling in Cirrhotic and Noncirrhotic NASH-HCC

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Human BCL10 Deficiency due to Homozygosity for a Rare Allele.

JOURNAL OF CLINICAL IMMUNOLOGY. Article. 40(2):388-398.
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Understanding the Spatial Topology of Artificial Immunological Synapses Assembled in T Cell-Redirecting Strategies: A Major Issue in Cancer Immunotherapy.

Frontiers In Cell And Developmental Biology. Article. 7:370-370.
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Update on C3 Glomerulopathy: A Complement-Mediated Disease.

NEPHRON. Review. 144(6):1-9.
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Evaluation of Polysaccharide Typhim Vi Antibody Response as a predictor of Humoral Immunodeficiency in Haematological Malignancies.

CLINICAL IMMUNOLOGY. Article. 210:108307-108307.
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Benedé-Ubieto R, Estévez-Vázquez O, Ramadori P, Cubero FJ, Nevzorova YA (2020).

Guidelines and Considerations for Metabolic Tolerance Tests in Mice

Diabetes Metabolic Syndrome and Obesity-Targets and Therapy. Review. 13:439-450.
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Integrated Analysis of a Noncoding RNA-Associated Competing Endogenous RNA Network in Non-Alcoholic Fatty Liver Disease

IEEE Access. Article. 8:88977-88989.
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2019

Cubero, FJ (2019).

Staging NAFLD: Diagnostic and Therapeutic Value of TAM Signaling.

CELLULAR AND MOLECULAR GASTROENTEROLOGY AND HEPATOLOGY. Editorial Material. 9(3):545-546.
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Chen, CB, Nelson, LJ, Avila, MA, Cubero, FJ (2019).

Mitogen-Activated Protein Kinases (MAPKs) and Cholangiocarcinoma: The Missing Link

Cells. Review. 8(10).
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Tortajada, A, Gutierrez, E, Pickering, MC, Praga Terente M, Medjeral-Thomas, N (2019).

The role of complement in IgA nephropathy.

MOLECULAR IMMUNOLOGY. Article. 114:123-132.
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Intestinal dysbiosis augments liver disease progression via NLRP3 in a murine model of primary sclerosing cholangitis

GUT. Article. 68(8):1477-1492.
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Editorial: Functional Relevance of Tetraspanins in the Immune System.

Frontiers in immunology. Editorial Material. 10:1714-1714.
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Development of a quantitative method to measure EV uptake.

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Human Oral Epithelial Cells Impair Bacteria-Mediated Maturation of Dendritic Cells and Render T Cells Unresponsive to Stimulation

Frontiers in immunology. Article. 10:1434-1434.
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Voltage controlled scattering from porous silicon Mie-particles in liquid crystals

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Adiponectin accounts for gender differences in hepatocellular carcinoma incidence

JOURNAL OF EXPERIMENTAL MEDICINE. Article. 216(5):1108-1119.
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Double-strand break repair through homologous recombination in autosomal-recessive BCL10 deficiency

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p38 gamma is essential for cell cycle progression and liver tumorigenesis

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Measurement of Typhim Vi IgG as a Diagnostic Tool to Determine Anti-polysaccharide Antibody Production Deficiency in Children

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Microbiota Sensing by Mincle-Syk Axis in Dendritic Cells Regulates Interleukin-17 and-22 Production and Promotes Intestinal Barrier Integrity

Immunity. Article. 50(2):446.
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Aurora A controls CD8(+) T cell cytotoxic activity and antiviral response

SCIENTIFIC REPORTS. Article. 9.
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Disruption of the FasL/Fas axis protects against inflammation-derived tumorigenesis in chronic liver disease

CELL DEATH & DISEASE. Article. 10.
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Molecular Players in Hematologic Tumor Cell Trafficking

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Mannaerts, I, Thoen, LFR, Eysackers, N, Cubero, FJ, Leite, SB, Coldham, I, Colle, I, Trautwein, C, van Grunsven, LA (2019).

Unfolded protein response is an early, non-critical event during hepatic stellate cell activation

CELL DEATH & DISEASE. Article. 10.
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Extreme Phenotypes With Identical Mutations: Two Patients With Same Non-sense NHEJ1 Homozygous Mutation

Frontiers in immunology. Article. 9:2959-2959.
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Dreger, M, Madrazo, E, Hurlstone, A, Redondo-Munoz, J (2019).

Novel contribution of epigenetic changes to nuclear dynamics

NUCLEUS. Review. 10(1):42-47.
[doi:10.1080/19491034.2019.1580100]
Regueiro, JR, Fernandez, FJ, Vega, MC (2019).

Complement in leucocyte development and function

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. Editorial Material. 85:84-85.
[doi:10.1016/j.semcdb.2018.02.024]
Lopez-Lera, A, Corvillo, F, Nozal, P, Regueiro, JR, Sanchez-Corral, P, Lopez-Trascasa, M (2019).

Complement as a diagnostic tool in immunopathology

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. Review. 85:86-97.
[doi:10.1016/j.semcdb.2017.12.017]
Marin AV, Cardenas PP, Jimenez-Reinoso A, Munoz-Ruiz M, Regueiro JR (2019).

Lymphocyte integration of complement cues

SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. Review. 85:132-142.
[doi:10.1016/j.semedb.2018.02.005]

2018

Lamas-Paz, A, Hao, FJ, Nelson, LJ, Vazquez, MT, Canals, S, Gómez Del Moral M, Martinez-Naves, E, Nevzorova, YA, Cubero, FJ (2018).

Alcoholic liver disease: Utility of animal models.

WORLD JOURNAL OF GASTROENTEROLOGY. Review. 24(45):5063-5075.
[doi:10.3748/wjg.v24.i45.5063]
Cubero, FJ, Peng, J, Liao, LJ, Su, H, Zhao, G, Zoubek, ME, Macias-Rodriguez, R, Ruiz-Margain, A, Reißing J, Zimmermann, HW, Gassler, N, Luedde, T, Liedtke, C, Hatting, M, Trautwein, C (2018).

Inactivation of caspase 8 in liver parenchymal cells confers protection against murine obstructive cholestasis.

JOURNAL OF HEPATOLOGY. Article. 69(6):1326-1334.
[doi:10.1016/j.jhep.2018.08.015]
Macias-Rodriguez, RU, Ruiz-Margain, A, Cantu-Brito, C, Flores-Silva DF, Garcia-Flores, OR, Cubero, FJ, Larrieta-Carrasco, E, Torre, A (2018).

Changes in Cerebral Hemodynamics in Patients With Cirrhosis After Liver Transplantation.

LIVER TRANSPLANTATION. Article. 24(12):1673-1679.
[doi:10.1002/lt.25335]
Castro-Sanchez, P, Ramirez-Munoz, R, Martin-Cofreces, NB, Aguilar-Sopena, O, Alegre-Gomez, S, Hernandez-Perez, S, Reyes, R, Zeng, Q, Cabañas C, Sanchez-Madrid, F, Roda-Navarro, P (2018).

Phosphatase of Regenerating Liver-1 (PRL-1) Regulates Actin Dynamics During Immunological Synapse Assembly and T Cell Effector Function.

Frontiers in immunology. Article. 9:2655-2655.
[doi:10.3389/fimmu.2018.02655]
Brazin, KN, Mallis, RJ, Boeszoermenyi, A, Feng, Y, Yoshizawa, A, Reche, PA, Kaur, P, Bi, K, Hussey, RE, Duke-Cohan, JS, Song, L, Wagner, G, Arthanari, H, Lang, MJ, Reinherz, EL (2018).

The T Cell Antigen Receptor alpha Transmembrane Domain Coordinates Triggering through Regulation of Bilayer Immersion and CD3 Subunit Associations

Immunity. Article. 49(5):829-829.
[doi:10.1016/j.immuni.2018.09.007]
Lopez-Palacios, N, Pascual, V, Castaño M, Bodas, A, Fernandez-Prieto, M, Espino-Paisan, L, Martinez-Ojinaga, E, Salazar, I, Martinez-Curiel, R, Rey, E, Estrada, L, Molero-Abraham, M, Reche, PA, Dieli-Crimi, R, Núñez C (2018).

Evaluation of T cells in blood after a short gluten challenge for coeliac disease diagnosis.

DIGESTIVE AND LIVER DISEASE. Article. 50(11):1183-1188.
[doi:10.1016/j.dld.2018.04.014]
Morán L, Cubero FJ (2018).

Extracellular vesicles in liver disease and beyond.

WORLD JOURNAL OF GASTROENTEROLOGY. Editorial Material. 24(40):4519-4526.
[doi:10.3748/wjg.v24.i40.4519]
Stephen, LA, ElMaghloob, Y, McIlwraith, MJ, Yelland, T, Castro Sanchez, Patricia, Roda-Navarro, P, Ismail, S (2018).

The Ciliary Machinery Is Repurposed for T Cell Immune Synapse Trafficking of LCK

DEVELOPMENTAL CELL. Article. 47(1):122-122.
[doi:10.1016/j.devcel.2018.08.012]
Guo, FF, Zheng, K, Benede-Ubieto, R, Cubero, FJ, Nevzorova, YA (2018).

The Lieber-DeCarli Diet-A Flagship Model for Experimental Alcoholic Liver Disease.

ALCOHOLISM-CLINICAL AND EXPERIMENTAL RESEARCH. Review. 42(10):1828-1840.
[doi:10.1111/acer.13840]
Goicoechea de Jorge E, Lopez Lera A, Bayarri-Olmos, R, Yebenes, H, Lopez-Trascasa, M, Rodriguez de Cordoba S (2018).

Common and rare genetic variants of complement components in human disease

MOLECULAR IMMUNOLOGY. Article. 102:42-57.
[doi:10.1016/j.molimm.2018.06.011]
Madrazo, E, Ruano, D, Abad, L, Alonso-Gomez, E, Sanchez-Valdepenas, C, Gonzalez-Murillo, A, Ramirez, M, Redondo-Munoz, J (2018).

G9a Correlates with VLA-4 Integrin and Influences the Migration of Childhood Acute Lymphoblastic Leukemia Cells

Cancers. Article. 10(9).
[doi:10.3390/cancers10090325]
Sonntag, R, Giebeler, N, Nevzorova, YA, Bangen, JM, Fahrenkamp, D, Lambertz, D, Haas, U, Hu, W, Gassier, N, Cubero, FJ, Muller-Newen, G, Abdallan, AT, Weiskirchen, R, Ticconi, F, Costa, IG, Barbacid, M, Trautwein, C, Liedtke, C (2018).

Cyclin E1 and cyclin-dependent kinase 2 are critical for initiation, but not for progression of hepatocellular carcinoma

PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA. Article. 115(37):9282-9287.
[doi:10.1073/pnas.1807155115]
Blaya, D, Aguilar-Bravo, B, Hao, FJ, Casacuberta-Serra, S, Coll, M, Perea, L, Vallverdu, J, Graupera, I, Pose, E, Llovet, L, Barquinero, J, Cubero, FJ, Caballeria, J, Gines, P, Sancho-Bru, P (2018).

Expression of microRNA-155 in inflammatory cells modulates liver injury

HEPATOLOGY. Article. 68(2):691-706.
[doi:10.1002/hep.29833]
Enamorado, M, Khouili, SC, Iborra, S, Sancho, D (2018).

Genealogy, Dendritic Cell Priming, and Differentiation of Tissue-Resident Memory CD8 + T Cells.

Frontiers in immunology. Review. 9:1751-1751.
[doi:10.3389/fimmu.2018.01751]
Lopez-Relano, J, Martin-Adrados, B, Real-Arevalo, I, Lozano-Bartolome, J, Abos, B, Sanchez-Ramon, S, Alonso, B, Gómez Del Moral M, Martinez-Naves, E (2018).

Monocyte-Derived Dendritic Cells Differentiated in the Presence of Lenalidomide Display a Semi-Mature Phenotype, Enhanced Phagocytic Capacity, and Th1 Polarization Capability.

Frontiers in immunology. Article. 9:1328-1328.
[doi:10.3389/fimmu.2018.01328]
Rowe, JH, Delmonte, OM, Keles, S, Stadinski, BD, Dobbs, AK, Henderson, LA, Yamazaki, Y, Allende, LM, Bonilla, FA, Gonzalez-Granado, LI, Celik, SC, Guner, SN, Kapakli, H, Yee, C, Pai, SY, Huseby, ES, Reisli, I, Regueiro, JR, Notarangelo, LD (2018).

Patients with CD3G mutations reveal a role for human CD3 gamma in T-reg diversity and suppressive function

BLOOD. Article. 131(21):2335-2344.
[doi:10.1182/blood-2018-02-835561]
Shah, P, Mistry, J, Reche, PA, Gatherer, D, Flower, DR (2018).

In silico design of Mycobacterium tuberculosis epitope ensemble vaccines

MOLECULAR IMMUNOLOGY. Article. 97:56-62.
[doi:10.1016/j.molimm.2018.03.007]
Bravo Garcia-Morato M, Aracil Santos FJ, Briones, AC, Blazquez Moreno A, Del Pozo Mate A, Dominguez-Soto, A, Beato Merino MJ, Del Pino Molina L, Torres Canizales J, Marin, AV, Vallespin Garcia E, Feito Rodriguez M, Plaza Lopez Sabando D, Jimenez-Reinoso, A, Mozo Del Castillo Y, Sanz Santaeufemia FJ, de Lucas-Laguna, R, Cardenas, PP, Casamayor Polo L, Coronel Diaz M, Vales-Gomez, M, Roldan Santiago E, Ferreira Cerdan A, Nevado Blanco J, Corbi, AL, Reyburn, HT, Regueiro, JR, Lopez-Granados, E, Rodriguez Pena R (2018).

New human combined immunodeficiency caused by interferon regulatory factor 4 (IRF4) deficiency inherited by uniparental isodisomy

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 141(5):1924.
[doi:10.1016/j.jaci.2017.12.995]
Ye, H, Nelson, LJ, Gómez Del Moral M, Martinez-Naves, E, Cubero, FJ (2018).

Dissecting the molecular pathophysiology of drug-induced liver injury.

WORLD JOURNAL OF GASTROENTEROLOGY. Review. 24(13):1373-1385.
[doi:10.3748/wjg.v24.i13.1373]
Jimenez-Reinoso A, Marin AV, Subias M, Lopez-Lera A, Roman-Ortiz E, Payne K, Ma CS, Arbore G, Kolev M, Freeley SJ, Kemper C, Tangye SG, Fernandez-Malave E, Rodriguez de Cordoba S, Lopez-Trascasa M, Regueiro JR (2018).

Human plasma C3 is essential for the development of memory B, but not T, lymphocytes

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 141(3):1151.
[doi:10.1016/j.jaci.2017.09.037]
Zoubek, ME, Gonzalez-Jimenez, A, Medina-Caliz, I, Robles-Diaz, M, Hernandez, N, Romero-Gomez, M, Bessone, F, Hallal, H, Cubero, FJ, Lucena, MI, Stephens, C, Andrade, RJ (2018).

LHigh Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. Article. 16(2):292-294.
[doi:10.1016/j.cgh.2017.07.037]
Merinero, HM, Garcia, SP, Garcia-Fernandez, J, Arjona, E, Tortajada, A, Rodriguez de Cordoba S (2018).

Complete functional characterization of disease-associated genetic variants in the complement factor H gene

KIDNEY INTERNATIONAL. Article. 93(2):470-481.
[doi:10.1016/j.kint.2017.07.015]
Goicoechea de Jorge E, Tortajada, A, Garcia, SP, Gastoldi, S, Merinero, HM, Garcia-Fernandez, J, Arjona, E, Cao, M, Remuzzi, G, Noris, M, Rodríguez de Córdoba S (2018).

Factor H Competitor Generated by Gene Conversion Events Associates with Atypical Hemolytic Uremic Syndrome

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Article. 29(1):240-249.
[doi:10.1681/ASN.2017050518]
de Jorge, EG, Yebenes, H, Serna, M, Tortajada, A, Llorca, O, de Cordoba, SR (2018).

How novel structures inform understanding of complement function

SEMINARS IN IMMUNOPATHOLOGY. Review. 40(1):3-14.
[doi:10.1007/s00281-017-0643-z]

2017

Sanchez-Trincado JL, Gomez-Perosanz M, Reche PA (2017).

Fundamentals and Methods for T- and B-Cell Epitope Prediction.

JOURNAL OF IMMUNOLOGY RESEARCH. Article. 2017:2680160-2680160.
[doi:10.1155/2017/2680160]
Damfo SA, Reche P, Gatherer D, Flower DR (2017).

In silico design of knowledge-based Plasmodium falciparum epitope ensemble vaccines

JOURNAL OF MOLECULAR GRAPHICS & MODELLING. Article. 78:195-205.
[doi:10.1016/j.jmgm.2017.10.004]
Hao F, Cubero FJ, Ramadori P, Liao L, Haas U, Lambertz D, Sonntag R, Bangen JM, Gassler N, Hoss M, Streetz KL, Reissing J, Zimmermann HW, Trautwein C, Liedtke C, Nevzorova YA (2017).

Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice

CELL DEATH & DISEASE. Article. 8(10).
[doi:10.1038/cddis.2017.532]
Tortajada A, Gutiérrez E, Goicoechea de Jorge E, Anter J, Segarra A, Espinosa M, Blasco M, Roman E, Marco H, Quintana LF, Gutiérrez J, Pinto S, Lopez-Trascasa M, Praga M, Rodriguez de Córdoba S (2017).

Elevated factor H-related protein 1 and factor H pathogenic variants; decrease complement regulation in IgA nephropathy

KIDNEY INTERNATIONAL. Article. 92(4):953-963.
[doi:10.1016/j.kint.2017.03.041]
Harwood, SL, Alvarez-Cienfuegos, A, Nuñez-Prado N, Compte, M, Hernandez-Perez, S, Merino, N, Bonet, J, Navarro, R, Van Bergen En Henegouwen PMP, Lykkemark, S, Mikkelsen, K, Mølgaard K, Jabs, F, Sanz, L, Blanco, FJ, Roda-Navarro, P, Alvarez-Vallina, L (2017).

ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy.

OncoImmunology. Article. 7(1).
[doi:10.1080/2162402X.2017.1377874]
Ramadori P, Cubero FJ, Liedtke C, Trautwein C, Nevzorova YA (2017).

Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame.

Cancers. Article. 9(10).
[doi:10.3390/cancers9100130]
Blázquez-Moreno A, Pérez-Portilla A, Agúndez-Llaca M, Dukovska D, Valés-Gómez M, Aydogmus C, Ikinciogullari A, Regueiro JR, Reyburn HT (2017).

Analysis of the recovery of CD247 expression in a PID patient: insights; into the spontaneous repair of defective genes

BLOOD. Article. 130(10):1205-1208.
[doi:10.1182/blood-2017-01-762864]
Bettoni, S, Galbusera, M, Gastoldi, S, Donadelli, R, Tentori, C, Sparta, G, Bresin, E, Mele, C, Alberti, M, Tortajada, A, Yebenes, H, Remuzzi, G, Noris, M (2017).

Interaction between Multimeric von Willebrand Factor and Complement: A; Fresh Look to the Pathophysiology of Microvascular Thrombosis

JOURNAL OF IMMUNOLOGY. Article. 199(3):1021-1040.
[doi:10.4049/jimmunol.1601121]
Castro-Sánchez P, Ramirez-Munoz R, Lamana A, Ortiz A, González-Álvaro I, Roda-Navarro P (2017).

mRNA profilin identifies low levels of phosphatases dual-specific phosphatase-7 (DUSP7) and cell division cycle-25B (CDC25B) in patients with early arthritis

CLINICAL AND EXPERIMENTAL IMMUNOLOGY. Article. 189(1):113-119.
[doi:10.1111/cei.12953]
Guasp P, Barnea E, González-Escribano MF, Jiménez-Reinoso A, Regueiro JR, Admon A, López de Castro JA (2017).

The Behcet's disease-associated variant of the aminopeptidase ERAP1; shapes a low-affinity HLA-B*51 peptidome by differential subpeptidome; processing

JOURNAL OF BIOLOGICAL CHEMISTRY. Article. 292(23):9680-9689.
[doi:10.1074/jbc.M117.789180]
Ramadori P, Drescher H, Erschfeld S, Fragoulis A, Kensler TW, Wruck CJ, Cubero FJ, Trautwein C, Streetz KL, Kroy DC (2017).

Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH

Oxidative Medicine And Cellular Longevity. Article. 2017:3420286-3420286.
[doi:10.1155/2017/3420286]
Abos Gracia B, López Relaño J, Revilla A, Castro L, Villalba M, Martín Adrados B, Regueiro JR, Fernández-Malavé E, Martínez Naves E, Gómez Del Moral M (2017).

Human Invariant Natural Killer T Cells Respond to Antigen-Presenting Cells Exposed to Lipids from Olea europaea Pollen

INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. Article. 173(1):12-22.
[doi:10.1159/000467394]
Kuttkat N, Mohs A, Ohl K, Hooiveld G, Longerich T, Tenbrock K, Cubero FJ, Trautwein C (2017).

Hepatic overexpression of cAMP-responsive element modulator a induces a regulatory T-cell response in a murine model of chronic liver disease.

GUT. Article. 66(5):908-919.
[doi:10.1136/gutjnl-2015-311119]
Zheng K, Cubero FJ, Nevzorova YA (2017).

c-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease

Genes. Review. 8(4).
[doi:10.3390/genes8040123]
Querol-García J, Fernández FJ, Marin AV, Gómez S, Fullà D, Melchor-Tafur C, Franco-Hidalgo V, Albertí S, Juanhuix J, Rodríguez de Córdoba S, Regueiro JR, Vega MC (2017).

Crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from the; Gram-Positive Bacterial Pathogen A. vaginae, an Immunoevasive Factor; that Interacts with the Human C5a Anaphylatoxin

FRONTIERS IN MICROBIOLOGY. Article. 8:541-541.
[doi:10.3389/fmicb.2017.00541]
Mohs A, Kuttkat N, Reißing J, Zimmermann HW, Sonntag R, Proudfoot A, Youssef SA, de Bruin A, Cubero FJ, Trautwein C (2017).

Functional role of CCL5/RANTES for HCC progression during chronic liver; disease

JOURNAL OF HEPATOLOGY. Article. 66(4):743-753.
[doi:10.1016/j.jhep.2016.12.011]
Jiménez-Reinoso A, Marin AV, Regueiro JR (2017).

Complement in basic processes of the cell

MOLECULAR IMMUNOLOGY. Article. 84(SI):10-16.
[doi:10.1016/j.molimm.2016.11.011]
Castro-Sánchez P, Ramirez-Munoz R, Roda-Navarro P (2017).

Gene Expression Profiles of Human Phosphotyrosine Phosphatases Consequent to Th1 Polarisation and Effector Function

JOURNAL OF IMMUNOLOGY RESEARCH. Article. 2017:8701042-8701042.
[doi:10.1155/2017/8701042]
Marin AV, Jiménez-Reinoso A, Briones AC, Muñoz-Ruiz M, Aydogmus C, Pasick LJ, Couso J, Mazariegos MS, Alvarez-Prado AF, Blázquez-Moreno A, Cipe FE, Haskologlu S, Dogu F, Morín M, Moreno-Pelayo MA, García-Sánchez F, Gil-Herrera J, Fernández-Malavé E, Reyburn HT, Ramiro AR, Ikinciogullari A, Recio MJ, Regueiro JR, Garcillán B (2017).

Primary T-cell immunodeficiency with functional revertant somatic mosaicism in CD247

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 139(1):347-347.
[doi:10.1016/j.jaci.2016.06.020]
Pennisi, Marzio, Sanchez-Lantaron, Juan A., Reche, Pedro A., Russo, Giulia, Pappalardo, Francesco (2017).

Optimization and analisys of vaccination schedules using Simulated Annealing and Agent Based Models

Ieee International Conference On Bioinformatics And Biomedicine-Bibm. Proceedings Paper. 1455-1460.
Sanchez-Lantaron, Juan A., Reche, Pedro A., Pennisi, Marzio, Russo, Giulia, Pappalardo, Francesco (2017).

Introducing scale factor adjustments on agent-based simulations of the immune system

Ieee International Conference On Bioinformatics And Biomedicine-Bibm. Proceedings Paper. 1461-1468.

2016

Alcover A, Di Bartolo V, Roda-Navarro P (2016).

Editorial: Molecular dynamics at the immunological Synapse

Frontiers in immunology. Editorial Material. 7:632-632.
[doi:10.3389/fimmu.2016.00632]
Ruiz-Margáin A, Macías-Rodríguez RU, Ampuero J, Cubero FJ, Chi-Cervera L, Ríos-Torres SL, Duarte-Rojo A, Espinosa-Cuevas Á, Romero-Gómez M, Torre A (2016).

Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis

WORLD JOURNAL OF GASTROENTEROLOGY. Article. 22(45):10064-10070.
[doi:10.3748/wjg.v22.i45.10064]
Teresa Martinez-Saavedra, Maria, Garcia-Gomez, Sonia, Dominguez Acosta, Ana, Mendoza Quintana, Juan Jesus, Poch Paez, Jesus, Garcia-Reino, Eduardo J., Camps, Gracian, Martinez-Barricarte, Ruben, Itan, Yuval, Boisson, Bertrand, Sanchez-Ramon, Silvia, Ramon Regueiro, Jose, Casanova, Jean-Laurent, Rodriguez-Gallego, Carlos, Perez de Diego, Rebeca (2016).

Gain-of-function mutation in PIK3R1 in a patient with a narrow clinical phenotype of respiratory infections

CLINICAL IMMUNOLOGY. Letter. 173:117-120.
[doi:10.1016/j.clim.2016.09.011]
Sheikh QM, Gatherer D, Reche PA, Flower DR (2016).

Towards the knowledge-based design of universal influenza epitope ensemble vaccines

Bioinformatics. Article. 32(21):3233-3239.
[doi:10.1093/bioinformatics/btw399]
Gutierrez Tenorio, Josue, Pinto Garcia, Sheila, Garcia-Fernandez, Jesus, Arjona, Emilia, Rodriguez de Cordoba, Santiago, Goicoechea de Jorge, Elena (2016).

Insight into the role of CFHR proteins in renal disease

Immunobiology. Meeting Abstract. 221(10, SI):1214-1214.
[doi:10.1016/j.imbio.2016.06.198]
Moreno A, Pineda F, Alcover J, Rodríguez D, Palacios R, Martínez-Naves E (2016).

Orthologous Allergens and Diagnostic Utility of Major Allergen Alt a 1

ALLERGY ASTHMA & IMMUNOLOGY RESEARCH. Article. 8(5):428-437.
[doi:10.4168/aair.2016.8.5.428]
Sirvent, S, Soria, I, Cirauqui, C, Cases, B, Manzano, AI, Diez-Rivero, CM, Reche, PA, Lopez-Relano, J, Martinez-Naves, E, Cañada FJ, Jimenez-Barbero, J, Subiza, J, Casanovas, M, Fernandez-Caldas, E, Subiza, JL, Palomares, O (2016).

Novel vaccines targeting dendritic cells by coupling allergoids to nonoxidized mannan enhance allergen uptake and induce functional regulatory T cells through programmed death ligand 1

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 138(2):558-558.
[doi:10.1016/j.jaci.2016.02.029]
Muñoz-Ruiz M, Ribot JC, Grosso AR, Gonçalves-Sousa N, Pamplona A, Pennington DJ, Regueiro JR, Fernández-Malavé E, Silva-Santos B (2016).

TCR signal strength controls thymic differentiation of discrete proinflammatory gamma delta T cell subsets

NATURE IMMUNOLOGY. Article. 17(6):721-721.
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Recalde, Sergio, Tortajada, Agustin, Subias, Marta, Anter, Jaouad, Blasco, Miguel, Maranta, Ramona, Coco, Rosa, Pinto, Sheila, Noris, Marina, Garcia-Layana, Alfredo, Rodriguez de Cordoba, Santiago (2016).

Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Article. 27(5):1305-1311.
[doi:10.1681/ASN.2015050580]
Valés-Gómez M, Esteso G, Aydogmus C, Blázquez-Moreno A, Marín AV, Briones AC, Garcillán B, García-Cuesta EM, Cobo SL, Haskologlu S, Moraru M, Cipe F, Dobbs K, Dogu F, Parolini S, Notarangelo LD, Vilches C, Recio MJ, Regueiro JR, Ikinciogullari A, Reyburn HT (2016).

Natural killer cell hyporesponsiveness and impaired development in a CD247-deficient patient

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 137(3):942-945.
[doi:10.1016/j.jaci.2015.07.051]
Ramirez-Munoz R, Castro-Sánchez P, Roda-Navarro P (2016).

Ultrasensitivity in the Cofilin Signaling Module: A Mechanism for Tuning T Cell Responses

Frontiers in immunology. Article. 7:59-59.
[doi:10.3389/fimmu.2016.00059]

2015

Echbarthi, Meriem, Zonca, Manuela, Mellwig, Rachel, Schwab, Yannick, Kaplan, Gerardo, DeKruyff, Rosemarie H., Roda-Navarro, Pedro, Casasnovas, Jose M. (2015).

Distinct Trafficking of Cell Surface and Endosomal TIM-1 to the Immune Synapse

Traffic. Article. 16(11):1193-1207.
[doi:10.1111/tra.12329]
Reyes R, Monjas A, Yánez-Mó M, Cardeñes B, Morlino G, Gilsanz A, Machado-Pineda Y, Lafuente E, Monk P, Sánchez-Madrid F, Cabañas C (2015).

Different states of integrin LFA-1 aggregation are controlled through its association with tetraspanin CD9

BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. Article. 1853(10):2464-2480.
[doi:10.1016/j.bbamcr.2015.05.018]
Rahman, Sunniyat, Pinto, Sheila, Hajji, Nabil, Rodriguez de Cordoba, Santiago, Goicoechea de Jorge, Elena (2015).

miRNAs as novel biomarkers of disease status in atypical haemolytic uremic syndrome

MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):172-173.
Marin, Ana V. M., Jimenez-Reinosol, Anais, Juana-Lopez, Lucia, Rodriguez de Cordoba, Santiago, Regueiro, Jose R. (2015).

Altered B cell and bone marrow-derived dendritic cell phenotype in mouse models with secondary C3 deficiency

MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):158-159.
Jimenez-Reinoso, Anais, Lopez-Lera, Alberto, Marin, Ana V. M., Lopez-Relano, Juan, Martinez-Naves, Eduardo, Rodriguez de Cordoba, Santiago, Roman-Ortiz, Elena, Lopez-Trascasa, Margarita, Regueiro, Jose R. (2015).

Differential impairment of dendritic, Band T cell differentiation in congenital primary (C3-deficient) as opposed to secondary (factor I-deficient) human plasma C3 deficiencies

MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):147-147.
Jimenez-Reinoso, Anais, Marin, Ana V. M., Lopez-Lera, Alberto, Rodriguez de Cordoba, Santiago, Roman-Ortiz, Elena, Lopez-Trascasa, Margarita, Regueiro, Jose R. (2015).

Severe congenital plasma C3 deficiency does not preclude intracellular C3 expression by immortalized T cell lines in two unrelated patients

MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):147-148.
Álvarez B, Escalona Z, Uenishi H, Toki D, Revilla C, Yuste M, Del Moral MG, Alonso F, Ezquerra A, Domínguez J (2015).

Molecular and functional characterization of porcine Siglec-3/CD33 and analysis of its expression in blood and tissues

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. Article. 51(2):238-250.
[doi:10.1016/j.dci.2015.04.002]
Jozsi, Mihaly, Tortajada, Agustin, Uzonyi, Barbara, Goicoechea de Jorge, Elena, Rodriguez de Cordoba, Santiago (2015).

Factor H-related proteins determine complement-activating surfaces

TRENDS IN IMMUNOLOGY. Review. 36(6):374-384.
[doi:10.1016/j.it.2015.04.008]
Csincsi ÁI, Kopp A, Zöldi M, Bánlaki Z, Uzonyi B, Hebecker M, Caesar JJ, Pickering MC, Daigo K, Hamakubo T, Lea SM, Goicoechea de Jorge E, Józsi M (2015).

Factor H-Related Protein 5 Interacts with Pentraxin 3 and the Extracellular Matrix and Modulates Complement Activation

JOURNAL OF IMMUNOLOGY. Article. 194(10):4963-4973.
[doi:10.4049/jimmunol.1403121]
Garcillán B, Marin AV, Jiménez-Reinoso A, Briones AC, Muñoz-Ruiz M, García-León MJ, Gil J, Allende LM, Martínez-Naves E, Toribio ML, Regueiro JR (2015).

gamma delta T lymphocytes in the diagnosis of human T cell receptor immunodeficiencies

Frontiers in immunology. Editorial Material. 6:20-20.
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López-Cotarelo P, Escribano-Díaz C, González-Bethencourt IL, Gómez-Moreira C, Deguiz ML, Torres-Bacete J, Gómez-Cabañas L, Fernández-Barrera J, Delgado-Martín C, Mellado M, Regueiro JR, Miranda-Carús ME, Rodríguez-Fernández JL (2015).

A Novel MEK-ERK-AMPK Signaling Axis Controls Chemokine Receptor CCR7-dependent Survival in Human Mature Dendritic Cells

JOURNAL OF BIOLOGICAL CHEMISTRY. Article. 290(2):827-840.
[doi:10.1074/jbc.M114.596551]
Molero-Abraham M, Glutting JP, Flower DR, Lafuente EM, Reche PA (2015).

EPIPOX: Immunoinformatic Characterization of the Shared T-Cell Epitome between Variola Virus and Related Pathogenic Orthopoxviruses

JOURNAL OF IMMUNOLOGY RESEARCH. Article. 2015:738020-738020.
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Escalona Z, Álvarez B, Uenishi H, Toki D, Yuste M, Revilla C, del Moral MG, Alonso F, Ezquerra A, Domínguez J (2015).

Molecular characterization of porcine Siglec-10 and analysis of its expression in blood and tissues

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. Article. 48(1):116-123.
[doi:10.1016/j.dci.2014.09.011]

2014

Manuel Torres, Juan, Martinez-Barricarte, Ruben, Garcia-Gomez, Sonia, Mazariegos, Marina S., Itan, Yuval, Boisson, Bertrand, Alvarez, Rita, Jimenez-Reinoso, Anais, del Pino, Lucia, Rodriguez-Pena, Rebeca, Ferreira, Antonio, Hernandez-Jimenez, Enrique, Toledano, Victor, Cubillos-Zapata, Carolina, Diaz-Almiron, Mariana, Lopez-Collazo, Eduardo, Unzueta-Roch, Jose L., Sanchez-Ramon, Silvia, Regueiro, Jose R., Lopez-Granados, Eduardo, Casanova, Jean-Laurent, Perez de Diego, Rebeca (2014).

Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity

JOURNAL OF CLINICAL INVESTIGATION. Article. 124(12):5239-5248.
[doi:10.1172/JCI77493]
Subias Hidalgo, Marta, Yebenes, Hugo, Dominguez, Mercedes, Jimenez, Anais, Regueiro, J. R., Llorca, Oscar, Rodriguez de Cordoba, Santiago (2014).

Dissection of C3 functions using novel mouse monoclonal antibodies to activated human C3 fragments

MOLECULAR IMMUNOLOGY. Meeting Abstract. 61(2, SI):253-254.
Roda-Navarro P, Bastiaens PI (2014).

Dynamic Recruitment of Protein Tyrosine Phosphatase PTPD1 to EGF Stimulation Sites Potentiates EGFR Activation

PLOS ONE. Article. 9(7).
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Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WW (2014).

The CD3 Conformational Change in the gamma delta T Cell Receptor Is Not Triggered by Antigens but Can Be Enforced to Enhance Tumor Killing

CELL REPORTS. Article. 7(5):1704-1715.
[doi:10.1016/j.celrep.2014.04.049]
Escalona Z, Álvarez B, Uenishi H, Toki D, Yuste M, Revilla C, Gómez del Moral M, Alonso F, Ezquerra A, Domínguez J (2014).

Molecular characterization and expression of porcine Siglec-5

DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. Article. 44(1):206-216.
[doi:10.1016/j.dci.2013.12.013]
Garcillán B, Mazariegos MS, Fisch P, Res PC, Muñoz-Ruiz M, Gil J, López-Granados E, Fernández-Malavé E, Regueiro JR (2014).

Enrichment of the rare CD4(+) gamma delta T-cell subset in patients with atypical CD3 delta deficiency

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 133(4):1205-1208.
[doi:10.1016/j.jaci.2013.10.002]

2013

Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS (2013).

Paneth cells as a site of origin for intestinal inflammation

Nature. Article. 503(7475):272-272.
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Medraño-Fernandez I, Reyes R, Olazabal I, Rodriguez E, Sanchez-Madrid F, Boussiotis VA, Reche PA, Cabañas C, Lafuente EM (2013).

RIAM (Rap1-interacting adaptor molecule) regulates complement-dependent phagocytosis

CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 70(13):2395-2410.
[doi:10.1007/s00018-013-1268-6]
Iborra S, Ramos M, Arana DM, Lázaro S, Aguilar F, Santos E, López D, Fernández-Malavé E, Del Val M (2013).

N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8(+) T cell memory but not to effector differentiation

JOURNAL OF EXPERIMENTAL MEDICINE. Article. 210(7):1463-1479.
[doi:10.1084/jem.20112495]
Abós-Gracia B, del Moral MG, López-Relaño J, Viana-Huete V, Castro L, Villalba M, Martínez-Naves E (2013).

Olea europaea pollen lipids activate invariant natural killer T cells by upregulating CD1d expression on dendritic cells

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 131(5):1393-221.
[doi:10.1016/j.jaci.2012.11.014]
Gilsanz A, Sánchez-Martín L, Gutiérrez-López MD, Ovalle S, Machado-Pineda Y, Reyes R, Swart GW, Figdor CG, Lafuente EM, Cabañas C (2013).

ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9

CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 70(3):475-493.
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Roda-Navarro P (2013).

Microspectroscopy reveals mechanisms of lymphocyte activation

INTEGRATIVE BIOLOGY. Review. 5(2):300-311.
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Munoz-Ruiz, Miguel, Perez-Flores, Veronica, Garcillan, Beatriz, Guardo, Alberto C., Mazariegos, Marina S., Takada, Hidetoshi, Allende, Luis M., Kilic, Sara S., Sanal, Ozden, Roifman, Chaim M., Lopez-Granados, Eduardo, Recio, Maria J., Martinez-Naves, Eduardo, Fernandez-Malave, Edgar, Regueiro, Jose R. (2013).

Human CD3 gamma, but not CD3 delta, haploinsufficiency differentially impairs gamma delta versus alpha beta surface TCR expression

BMC IMMUNOLOGY. Article. 14(3):3-3.
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Munoz-Ruiz, M., Mazariegos, M. S., Garcillan, B., Sanz, M., Delgado, M., Fernandez-Malave, E., Regueiro, J. R. (2013).

Cd3 haploinsufficiencies reveal the existence of differential CD3 chain functions in murine alpha beta T cell development, phenotype and function.

Proceedings Of The 15th Meeting Of The European Society Immunodeficiencies (esid). Capítulo de un Libro. 105-110.
Molero-Abraham M, Lafuente EM, Flower DR, Reche PA (2013).

Selection of Conserved Epitopes from Hepatitis C Virus for Pan-Populational Stimulation of T-Cell Responses

CLINICAL & DEVELOPMENTAL IMMUNOLOGY. Article. 2013:601943-601943.
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Jiménez-Periáñez A, Abos Gracia B, López Relaño J, Diez-Rivero CM, Reche PA, Martínez-Naves E, Matveyeva E, Gómez del Moral M (2013).

Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells

CLINICAL & DEVELOPMENTAL IMMUNOLOGY. Article. 2013:362163-362163.
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2012

García-Zaragoza E, Pérez-Tavarez R, Ballester A, Lafarga V, Jiménez-Reinoso A, Ramírez A, Murillas R, Gallego MI (2012).

Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland

DEVELOPMENTAL BIOLOGY. Article. 372(1):28-44.
[doi:10.1016/j.ydbio.2012.09.005]
Coló GP, Lafuente EM, Teixidó J (2012).

The MRL proteins: Adapting cell adhesion, migration and growth

EUROPEAN JOURNAL OF CELL BIOLOGY. Review. 91(11-12):861-868.
[doi:10.1016/j.ejcb.2012.03.001]
Argilaguet, Jordi M., Perez-Martin, Eva, Nofrarias, Miquel, Gallardo, Carmina, Accensi, Francesc, Lacasta, Anna, Mora, Mercedes, Ballester, Maria, Galindo-Cardiel, Ivan, Lopez-Soria, Sergio, Escribano, Jose M., Reche, Pedro A., Rodriguez, Fernando (2012).

DNA Vaccination Partially Protects against African Swine Fever Virus Lethal Challenge in the Absence of Antibodies

PLOS ONE. Article. 7(9).
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Recio, M. J., Couso, J., Busto, E., Allende, L. M., van Montfrans, J., Lefranc, G., Pablos, J. L., Regueiro, J. R. (2012).

THE CD3G P.V131F MUTATION IN IMMUNODEFICIENCY AND AUTOIMMUNITY

JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):320-321.
Ruiz-Garcia, R., Recio, M. J., Dominguez-Pinilla, N., Mancebo, E., Martinez-Feito, A., Mora, S., Ramirez-Munoz, R., Menchen, M., Diaz-Madronero, M. J., Regueiro, J. R., Ruiz-Contreras, J., Paz-Artal, E., Allende-Martinez, L., Gonzalez-Granado, L. I. (2012).

NON-HOMOLOGOUS END-JOINING DEFECTS WITHIN DNA-REPAIRING DEFECTS: WIDE CLINICAL SPECTRUM AND OUTCOME IN A TERTIARY SINGLE HOSPITAL

JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):313-314.
Garcillan, B., Mazariegos, M. S., Fish, P., Munoz-Ruiz, M., Gil, J., Lopez-Granados, E., Recio, M. J., Regueiro, J. (2012).

CHARACTERIZATION OF Gamma Delta T LYMPHOCYTES IN TAB(-)T Gamma Delta plus B plus NK plus SCID DUE TO LEAKY CD3D MUTATIONS

JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):308-308.
Munoz-Ruiz, M., Mazariegos, M. S., Garcillan, B., Delgado, M., Fernandez-Malave, E., Regueiro, J. R. (2012).

Selective roles of CD3 chains in T cell development, TCR expression and T cell effector functions revealed by CD3 haploinsufficiencies

Immunology. Meeting Abstract. 137(1, SI):10-10.
Mazariegos, M. S., Garcillan, B., Munoz-Ruiz, M., Regueiro, J. R. (2012).

Physiopathology of TCR/CD3: genomic induction in CD3gamma deficient cells

Immunology. Meeting Abstract. 137(1, SI):377-378.
Garcillan, B., Mazariegos, M. S., Fish, P., Munoz-Ruiz, M., Gil, J., Lopez-Granados, E., Regueiro, J. R. (2012).

Study of gamma delta T cells in a Tab-Tgd plus B plus NK plus SCID due to CD3D mutations

Immunology. Meeting Abstract. 137(1, SI):569-569.
Munoz-Ruiz, M., Mazariegos, M. S., Garcillan, B., Delgado, M., Fernandez-Malave, E., Regueiro, J. R. (2012).

CD3 HAPLOINSUFFICIENCIES REVEAL THE EXISTENCE OF DIFFERENTIAL CD3 CHAIN FUNCTIONS IN MURINE.. T CELL DEVELOPMENT, PHENOTYPE AND FUNCTION EX AND IN VIVO

JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):19-20.
Diez-Rivero, Carmen M., Reche, Pedro A. (2012).

CD8 T Cell Epitope Distribution in Viruses Reveals Patterns of Protein Biosynthesis

PLOS ONE. Article. 7(8).
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Beltrán E, Hernández A, Lafuente EM, Coret F, Simó-Castelló M, Boscá I, Pérez-Miralles FC, Burgal M, Casanova B (2012).

Neuronal antigens recognized by cerebrospinal fluid IgM in multiple sclerosis

JOURNAL OF NEUROIMMUNOLOGY. Article. 247(1-2):63-69.
[doi:10.1016/j.jneuroim.2012.03.013]
Zakka, Labib R., Reche, Pedro A., Ahmed, A. Razzaque (2012).

The molecular basis for the presence of two autoimmune diseases occurring simultaneously - Preliminary observations based on computer analysis

AUTOIMMUNITY. Article. 45(3):253-263.
[doi:10.3109/08916934.2011.632454]
Muñoz Ruiz M, Regueiro JR (2012).

NEW TOOLS IN REGENERATIVE MEDICINE: Gene Therapy

Advances in Experimental Medicine and Biology. Article. 741:254-275.
[doi:10.1007/978-1-4614-2098-9_17]

2011

Martinez-Naves, Eduardo, Lafuente, Esther M., Reche, Pedro A. (2011).

Recognition of the ligand-type specificity of classical and non-classical MHC I proteins

FEBS LETTERS. Article. 585(21):3478-3484.
[doi:10.1016/j.febslet.2011.10.007]
Zakka, L. R., Reche, P., Ahmed, A. R. (2011).

Role of MHC Class II Genes in the pathogenesis of pemphigoid

AUTOIMMUNITY REVIEWS. Review. 11(1):40-47.
[doi:10.1016/j.autrev.2011.07.002]
Marcus, Nufar, Takada, Hidetoshi, Law, Jason, Cowan, Morton J., Gil, Juana, Regueiro, Jose R., Lopez de Sabando, Diego Plaza, Lopez-Granados, Eduardo, Dalal, Jignesh, Friedrich, Wilhelm, Manfred, Hoenig, Hanson, Imelda Celine, Grunebaum, Eyal, Shearer, William T., Roifman, Chaim M. (2011).

Hematopoietic stem cell transplantation for CD3 delta deficiency

JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 128(5):1050-1057.
[doi:10.1016/j.jaci.2011.05.031]
Gil, Juana, Busto, Elena M., Garcillan, Beatriz, Chean, Carmen, Cruz Garcia-Rodriguez, Maria, Diaz-Alderete, Andrea, Navarro, Joaquin, Reine, Jesus, Mencia, Angeles, Gurbindo, Dolores, Belendez, Cristina, Gordillo, Isabel, Duchniewicz, Marlena, Hoehne, Kerstin, Garcia-Sanchez, Felix, Fernandez-Cruz, Eduardo, Lopez-Granados, Eduardo, Schamel, Wolfgang W. A., Moreno-Pelayo, Miguel A., Recio, Maria J., Regueiro, Jose R. (2011).

A leaky mutation in CD3D differentially affects alpha beta and gamma delta T cells and leads to a T alpha beta T-gamma delta+B+NK+ human SCID

JOURNAL OF CLINICAL INVESTIGATION. Article. 121(10):3872-3876.
[doi:10.1172/JCI44254]
Dolores Gutierrez-Lopez, Maria, Gilsanz, Alvaro, Yanez-Mo, Maria, Ovalle, Susana, Lafuente, Esther M., Dominguez, Carmen, Monk, Peter N., Gonzalez-Alvaro, Isidoro, Sanchez-Madrid, Francisco, Cabanas, Carlos (2011).

The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9

CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 68(19):3275-3292.
[doi:10.1007/s00018-011-0639-0]
Abos, Beatriz, Gomez del Moral, Manuel, Gozalbo-Lopez, Beatriz, Lopez-Relano, Juan, Viana, Vanesa, Martinez-Naves, Eduardo (2011).

Human MR1 expression on the cell surface is acid sensitive, proteasome independent and increases after culturing at 26 degrees C

BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. Article. 411(3):632-636.
[doi:10.1016/j.bbrc.2011.07.007]
Hernandez-Varas, Pablo, Colo, Georgina P., Bartolome, Ruben A., Paterson, Andrew, Medrano-Fernandez, Iria, Arellano-Sanchez, Nohem, Cabanas, Carlos, Sanchez-Mateos, Paloma, Lafuente, Esther M., Boussiotis, Vassiliki A., Stromblad, Staffan, Teixido, Joaquin (2011).

Rap1-GTP-interacting Adaptor Molecule (RIAM) Protein Controls Invasion and Growth of Melanoma Cells

JOURNAL OF BIOLOGICAL CHEMISTRY. Article. 286(21):18492-18504.
[doi:10.1074/jbc.M110.189811]
Iborra S, Soto M, Stark-Aroeira L, Castellano E, Alarcón B, Alonso C, Santos E, Fernández-Malavé E (2011).

H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity

BLOOD. Article. 117(19):5102-5111.
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Fernández-Malavé E, Stark-Aroeira L (2011).

A natural anti-T-cell receptor monoclonal antibody protects against experimental autoimmune encephalomyelitis

JOURNAL OF NEUROIMMUNOLOGY. Article. 234(1-2):63-70.
[doi:10.1016/j.jneuroim.2011.02.006]
Marcus, N., Takada, H., Dalal, J., Regueiro, J. R., Friedrich, W., Roifman, C. (2011).

STEM CELL TRANSPLANTATION FOR CD3-DELTA DEFICIENCY

BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. Meeting Abstract. 17(2, 2):184-184.
[doi:10.1016/j.bbmt.2010.12.096]
Mancebo, Esther, Jose Recio, Maria, Martinez-Busto, Elena, Gonzalez-Granado, Luis I., Rojo, Pablo, Fernandez-Diaz, Eva, Ruiz-Contreras, Jesus, Paz-Artal, Estela, Allende, Luis M. (2011).

Possible role of Artemis c.512C > G polymorphic variant in Omenn syndrome

Dna Repair. Letter. 10(1):3-4.
[doi:10.1016/j.dnarep.2010.09.022]
Reine, Jesus, Busto, Elena M., Munoz-Ruiz, Miguel, Rossi, Nineth E., Rodriguez-Fernandez, Jose L., Martinez-Naves, Eduardo, Regueiro, Jose R., Recio, Maria J. (2011).

CD3 gamma-independent pathways in TCR-mediated signaling in mature T and iNKT lymphocytes

CELLULAR IMMUNOLOGY. Article. 271(1):62-66.
[doi:10.1016/j.cellimm.2011.06.009]

2010

Zakka, L. R., Keskin, D. B., Reche, P., Ahmed, A. R. (2010).

Relationship between target antigens and major histocompatibility complex (MHC) class II genes in producing two pathogenic antibodies simultaneously

CLINICAL AND EXPERIMENTAL IMMUNOLOGY. Review. 162(2):224-236.
[doi:10.1111/j.1365-2249.2010.04239.x]
Berger, Scott B., Romero, Xavier, Ma, Chunyan, Wang, Guoxing, Faubion, William A., Liao, Gongxian, Compeer, Ewoud, Keszei, Marton, Rameh, Lucia, Wang, Ninghai, Boes, Marianne, Regueiro, Jose R., Reinecker, Hans-Christian, Terhorst, Cox (2010).

SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages

NATURE IMMUNOLOGY. Article. 11(10):920-70.
[doi:10.1038/ni.1931]
Diez-Rivero, Carmen M., Lafuente, Esther M., Reche, Pedro A. (2010).

Computational analysis and modeling of cleavage by the immunoproteasome and the constitutive proteasome

BMC BIOINFORMATICS. Article. 11(479):479-479.
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Liao, Gongxian, Nayak, Sushrusha, Regueiro, Jose R., Berger, Scott B., Detre, Cynthia, Romero, Xavier, Malefyt, Rene de Waal, Chatila, Talal A., Herzog, Roland W., Terhorst, Cox (2010).

GITR engagement preferentially enhances proliferation of functionally competent CD4(+)CD25(+)FoxP3(+) regulatory T cells

INTERNATIONAL IMMUNOLOGY. Article. 22(4):259-270.
[doi:10.1093/intimm/dxq001]

Arechederra, M, Rullan, M, Amat, I, Oyon, D, Zabalza, L, Elizalde, M, Latasa, MU, Mercado, MR, Ruiz-Clavijo, D, Saldana, C, Fernandez-Urien, I, Carrascosa, J, Jusue, V, Guerrero-Setas, D, Zazpe, C, Gonzalez-Borja, I, Sangro, B, Herranz, JM, Purroy, A, Gil, I, Nelson, LJ, Vila, JJ, Krawczyk, M, Zieniewicz, K, Patkowski, W, Milkiewicz, P, Cubero, FJ, Alkorta-Aranburu, G, Fernandez-Barrena, MG, Urman, JM, Berasain, C, Avila, MA ().

Next-generation sequencing of bile cell-free DNA for the early detection of patients with malignant biliary strictures

GUT. Article.
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Martínez-Saavedra MT, García-Gomez S, Domínguez Acosta A, Mendoza Quintana JJ, Páez JP, García-Reino EJ, Camps G, Martinez-Barricarte R, Itan Y, Boisson B, Sánchez-Ramón S, Regueiro JR, Casanova JL, Rodríguez-Gallego C, Pérez de Diego R ().

Gain-of-function mutation in PIK3R1 in a patient with a narrow clinical phenotype of respiratory infections.

CLINICAL IMMUNOLOGY. Letter.
[doi:10.1016/j.clim.2016.09.011]
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