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Lymphocyte Immunobiology


The group was established in 2000, recognized by the Complutense Univ. (UCM) in 2004 and externally evaluated in 2005, 2007 and 2008 by the Governmental Evaluation Agency ANEP with the highest scores among immunology teams at UCM (85, 78 and 89%, respectively). In the last internal evaluation by UCM, in 2014, it ranked 1st of 8 immunology teams at UCM and 5th of 32 groups at the UCM School of Medicine. It joined both the Moncloa International Excellence Campus (Innovative Medicine cluster, 2009) and the 12 de Octubre Health Research Institute (imas12, 2011) at the time of their creation. All researchers share scientific interests, facilities, papers, projects, training programs (see below) and weekly lab seminars, as well as a strong commitment towards internationalization by supporting both staff sabbaticals and hiring young scientists under the Juan de la Cierva , Ramón  y Cajal and I3 programs.

Scientific interests and research lines

We study lymphocyte immunobiology and inflammation with genetic, cellular, molecular and bioinformatic approaches (PhD staff in brackets, currently 13):

  • Antigen-presenting cells and molecules (Martinez-Naves E, Gomez del Moral M)
  • Cell adhesion and intracellular signalling (Lafuente EM)
  • Cell migration and epigenetics (Redondo-Muñoz J)
  • Complement physiopathology (Goicoechea E, Tortajada A)
  • Immune synapse and intracellular signalling (Roda-Navarro P)
  • Immunomedicine/epitomics (Reche PA)
  • Liver injury and inflammation (Cubero FJ)
  • T cell physiopathology (Regueiro JR, Fernandez-Malave E, Recio MJ, Cardenas PP)

 Training programs

The group is involved in two higher academic Aneca-certified postgraduate programs run by the UCM:

  1. Master´s degree in Immunology since 2010 (around 5 students/year)
  2. PhD program in Biomedical Research since 2013 (currently 16 students enrolled, 3 with Harvard UCM joint supervisors)

Both programs require attendance to a number of research seminars. In addition, the group has weekly (Fridays) lab meetings. Attendance to research seminars (CBM, CNB, CIB, CNIC, CNIO, Hospital 12 de Octubre) in other centers is promoted through a physical notice board and by virtual procedures (email, web site). The group promotes attendance to national and international meetings. All students and postdocs receive personal email, and we encourage the use of journal electronic subscriptions and etocs (electronic table of contents). PhD students are encouraged to train abroad to apply for an international PhD mention (at least 3 months abroad and an international evaluation board).