Publications
2019
Marin AV, Cardenas PP, Jimenez-Reinoso A, Munoz-Ruiz M, Regueiro JR (2019).
Lymphocyte integration of complement cues
SEMINARS IN CELL & DEVELOPMENTAL BIOLOGY. Review. 85:132-142.
[doi:10.1016/j.semedb.2018.02.005]
2018
Rowe, JH, Delmonte, OM, Keles, S, Stadinski, BD, Dobbs, AK, Henderson, LA, Yamazaki, Y, Allende, LM, Bonilla, FA, Gonzalez-Granado, LI, Celik, SC, Guner, SN, Kapakli, H, Yee, C, Pai, SY, Huseby, ES, Reisli, I, Regueiro, JR, Notarangelo, LD (2018).
Patients with CD3G mutations reveal a role for human CD3 gamma in T-reg diversity and suppressive function
BLOOD. Article. 131(21):2335-2344.
[doi:10.1182/blood-2018-02-835561]
Bravo Garcia-Morato M, Aracil Santos FJ, Briones, AC, Blazquez Moreno A, Del Pozo Mate A, Dominguez-Soto, A, Beato Merino MJ, Del Pino Molina L, Torres Canizales J, Marin, AV, Vallespin Garcia E, Feito Rodriguez M, Plaza Lopez Sabando D, Jimenez-Reinoso, A, Mozo Del Castillo Y, Sanz Santaeufemia FJ, de Lucas-Laguna, R, Cardenas, PP, Casamayor Polo L, Coronel Diaz M, Vales-Gomez, M, Roldan Santiago E, Ferreira Cerdan A, Nevado Blanco J, Corbi, AL, Reyburn, HT, Regueiro, JR, Lopez-Granados, E, Rodriguez Pena R (2018).
New human combined immunodeficiency caused by interferon regulatory factor 4 (IRF4) deficiency inherited by uniparental isodisomy
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 141(5):1924.
[doi:10.1016/j.jaci.2017.12.995]
Jimenez-Reinoso A, Marin AV, Subias M, Lopez-Lera A, Roman-Ortiz E, Payne K, Ma CS, Arbore G, Kolev M, Freeley SJ, Kemper C, Tangye SG, Fernandez-Malave E, Rodriguez de Cordoba S, Lopez-Trascasa M, Regueiro JR (2018).
Human plasma C3 is essential for the development of memory B, but not T, lymphocytes
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 141(3):1151.
[doi:10.1016/j.jaci.2017.09.037]
Zoubek, ME, Gonzalez-Jimenez, A, Medina-Caliz, I, Robles-Diaz, M, Hernandez, N, Romero-Gomez, M, Bessone, F, Hallal, H, Cubero, FJ, Lucena, MI, Stephens, C, Andrade, RJ (2018).
LHigh Prevalence of Ibuprofen Drug-Induced Liver Injury in Spanish and Latin-American Registries
CLINICAL GASTROENTEROLOGY AND HEPATOLOGY. Article. 16(2):292-294.
[doi:10.1016/j.cgh.2017.07.037]
Merinero, HM, Garcia, SP, Garcia-Fernandez, J, Arjona, E, Tortajada, A, Rodriguez de Cordoba S (2018).
Complete functional characterization of disease-associated genetic variants in the complement factor H gene
KIDNEY INTERNATIONAL. Article. 93(2):470-481.
[doi:10.1016/j.kint.2017.07.015]
Goicoechea de Jorge E, Tortajada, A, Garcia, SP, Gastoldi, S, Merinero, HM, Garcia-Fernandez, J, Arjona, E, Cao, M, Remuzzi, G, Noris, M, Rodríguez de Córdoba S (2018).
Factor H Competitor Generated by Gene Conversion Events Associates with Atypical Hemolytic Uremic Syndrome
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Article. 29(1):240-249.
[doi:10.1681/ASN.2017050518]
de Jorge, EG, Yebenes, H, Serna, M, Tortajada, A, Llorca, O, de Cordoba, SR (2018).
How novel structures inform understanding of complement function
SEMINARS IN IMMUNOPATHOLOGY. Review. 40(1):3-14.
[doi:10.1007/s00281-017-0643-z]
2017
Sanchez-Trincado JL, Gomez-Perosanz M, Reche PA (2017).
Fundamentals and Methods for T- and B-Cell Epitope Prediction.
JOURNAL OF IMMUNOLOGY RESEARCH. Article. 2017:2680160-2680160.
[doi:10.1155/2017/2680160]
Damfo SA, Reche P, Gatherer D, Flower DR (2017).
In silico design of knowledge-based Plasmodium falciparum epitope ensemble vaccines
JOURNAL OF MOLECULAR GRAPHICS & MODELLING. Article. 78:195-205.
[doi:10.1016/j.jmgm.2017.10.004]
Hao F, Cubero FJ, Ramadori P, Liao L, Haas U, Lambertz D, Sonntag R, Bangen JM, Gassler N, Hoss M, Streetz KL, Reissing J, Zimmermann HW, Trautwein C, Liedtke C, Nevzorova YA (2017).
Inhibition of Caspase-8 does not protect from alcohol-induced liver apoptosis but alleviates alcoholic hepatic steatosis in mice
CELL DEATH & DISEASE. Article. 8(10).
[doi:10.1038/cddis.2017.532]
Tortajada A, Gutiérrez E, Goicoechea de Jorge E, Anter J, Segarra A, Espinosa M, Blasco M, Roman E, Marco H, Quintana LF, Gutiérrez J, Pinto S, Lopez-Trascasa M, Praga M, Rodriguez de Córdoba S (2017).
Elevated factor H-related protein 1 and factor H pathogenic variants; decrease complement regulation in IgA nephropathy
KIDNEY INTERNATIONAL. Article. 92(4):953-963.
[doi:10.1016/j.kint.2017.03.041]
Harwood, SL, Alvarez-Cienfuegos, A, Nuñez-Prado N, Compte, M, Hernandez-Perez, S, Merino, N, Bonet, J, Navarro, R, Van Bergen En Henegouwen PMP, Lykkemark, S, Mikkelsen, K, Mølgaard K, Jabs, F, Sanz, L, Blanco, FJ, Roda-Navarro, P, Alvarez-Vallina, L (2017).
ATTACK, a novel bispecific T cell-recruiting antibody with trivalent EGFR binding and monovalent CD3 binding for cancer immunotherapy.
OncoImmunology. Article. 7(1).
[doi:10.1080/2162402X.2017.1377874]
Ramadori P, Cubero FJ, Liedtke C, Trautwein C, Nevzorova YA (2017).
Alcohol and Hepatocellular Carcinoma: Adding Fuel to the Flame.
Cancers. Article. 9(10).
[doi:10.3390/cancers9100130]
Blázquez-Moreno A, Pérez-Portilla A, Agúndez-Llaca M, Dukovska D, Valés-Gómez M, Aydogmus C, Ikinciogullari A, Regueiro JR, Reyburn HT (2017).
Analysis of the recovery of CD247 expression in a PID patient: insights; into the spontaneous repair of defective genes
BLOOD. Article. 130(10):1205-1208.
[doi:10.1182/blood-2017-01-762864]
Bettoni, S, Galbusera, M, Gastoldi, S, Donadelli, R, Tentori, C, Sparta, G, Bresin, E, Mele, C, Alberti, M, Tortajada, A, Yebenes, H, Remuzzi, G, Noris, M (2017).
Interaction between Multimeric von Willebrand Factor and Complement: A; Fresh Look to the Pathophysiology of Microvascular Thrombosis
JOURNAL OF IMMUNOLOGY. Article. 199(3):1021-1040.
[doi:10.4049/jimmunol.1601121]
Castro-Sánchez P, Ramirez-Munoz R, Lamana A, Ortiz A, González-Álvaro I, Roda-Navarro P (2017).
mRNA profilin identifies low levels of phosphatases dual-specific phosphatase-7 (DUSP7) and cell division cycle-25B (CDC25B) in patients with early arthritis
CLINICAL AND EXPERIMENTAL IMMUNOLOGY. Article. 189(1):113-119.
[doi:10.1111/cei.12953]
Guasp P, Barnea E, González-Escribano MF, Jiménez-Reinoso A, Regueiro JR, Admon A, López de Castro JA (2017).
The Behcet's disease-associated variant of the aminopeptidase ERAP1; shapes a low-affinity HLA-B*51 peptidome by differential subpeptidome; processing
JOURNAL OF BIOLOGICAL CHEMISTRY. Article. 292(23):9680-9689.
[doi:10.1074/jbc.M117.789180]
Ramadori P, Drescher H, Erschfeld S, Fragoulis A, Kensler TW, Wruck CJ, Cubero FJ, Trautwein C, Streetz KL, Kroy DC (2017).
Genetic Nrf2 Overactivation Inhibits the Deleterious Effects Induced by Hepatocyte-Specific c-met Deletion during the Progression of NASH
Oxidative Medicine And Cellular Longevity. Article. 2017:3420286-3420286.
[doi:10.1155/2017/3420286]
Abos Gracia B, López Relaño J, Revilla A, Castro L, Villalba M, Martín Adrados B, Regueiro JR, Fernández-Malavé E, Martínez Naves E, Gómez Del Moral M (2017).
Human Invariant Natural Killer T Cells Respond to Antigen-Presenting Cells Exposed to Lipids from Olea europaea Pollen
INTERNATIONAL ARCHIVES OF ALLERGY AND IMMUNOLOGY. Article. 173(1):12-22.
[doi:10.1159/000467394]
Kuttkat N, Mohs A, Ohl K, Hooiveld G, Longerich T, Tenbrock K, Cubero FJ, Trautwein C (2017).
Hepatic overexpression of cAMP-responsive element modulator a induces a regulatory T-cell response in a murine model of chronic liver disease.
GUT. Article. 66(5):908-919.
[doi:10.1136/gutjnl-2015-311119]
Zheng K, Cubero FJ, Nevzorova YA (2017).
c-MYC-Making Liver Sick: Role of c-MYC in Hepatic Cell Function, Homeostasis and Disease
Genes. Review. 8(4).
[doi:10.3390/genes8040123]
Querol-García J, Fernández FJ, Marin AV, Gómez S, Fullà D, Melchor-Tafur C, Franco-Hidalgo V, Albertí S, Juanhuix J, Rodríguez de Córdoba S, Regueiro JR, Vega MC (2017).
Crystal Structure of Glyceraldehyde-3-Phosphate Dehydrogenase from the; Gram-Positive Bacterial Pathogen A. vaginae, an Immunoevasive Factor; that Interacts with the Human C5a Anaphylatoxin
FRONTIERS IN MICROBIOLOGY. Article. 8:541-541.
[doi:10.3389/fmicb.2017.00541]
Mohs A, Kuttkat N, Reißing J, Zimmermann HW, Sonntag R, Proudfoot A, Youssef SA, de Bruin A, Cubero FJ, Trautwein C (2017).
Functional role of CCL5/RANTES for HCC progression during chronic liver; disease
JOURNAL OF HEPATOLOGY. Article. 66(4):743-753.
[doi:10.1016/j.jhep.2016.12.011]
Jiménez-Reinoso A, Marin AV, Regueiro JR (2017).
Complement in basic processes of the cell
MOLECULAR IMMUNOLOGY. Article. 84(SI):10-16.
[doi:10.1016/j.molimm.2016.11.011]
Castro-Sánchez P, Ramirez-Munoz R, Roda-Navarro P (2017).
Gene Expression Profiles of Human Phosphotyrosine Phosphatases Consequent to Th1 Polarisation and Effector Function
JOURNAL OF IMMUNOLOGY RESEARCH. Article. 2017:8701042-8701042.
[doi:10.1155/2017/8701042]
Marin AV, Jiménez-Reinoso A, Briones AC, Muñoz-Ruiz M, Aydogmus C, Pasick LJ, Couso J, Mazariegos MS, Alvarez-Prado AF, Blázquez-Moreno A, Cipe FE, Haskologlu S, Dogu F, Morín M, Moreno-Pelayo MA, García-Sánchez F, Gil-Herrera J, Fernández-Malavé E, Reyburn HT, Ramiro AR, Ikinciogullari A, Recio MJ, Regueiro JR, Garcillán B (2017).
Primary T-cell immunodeficiency with functional revertant somatic mosaicism in CD247
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 139(1):347-347.
[doi:10.1016/j.jaci.2016.06.020]
Pennisi, Marzio, Sanchez-Lantaron, Juan A., Reche, Pedro A., Russo, Giulia, Pappalardo, Francesco (2017).
Optimization and analisys of vaccination schedules using Simulated Annealing and Agent Based Models
Ieee International Conference On Bioinformatics And Biomedicine-Bibm. Proceedings Paper. 1455-1460.
Sanchez-Lantaron, Juan A., Reche, Pedro A., Pennisi, Marzio, Russo, Giulia, Pappalardo, Francesco (2017).
Introducing scale factor adjustments on agent-based simulations of the immune system
Ieee International Conference On Bioinformatics And Biomedicine-Bibm. Proceedings Paper. 1461-1468.
2016
Alcover A, Di Bartolo V, Roda-Navarro P (2016).
Editorial: Molecular dynamics at the immunological Synapse
Frontiers in immunology. Editorial Material. 7:632-632.
[doi:10.3389/fimmu.2016.00632]
Ruiz-Margáin A, Macías-Rodríguez RU, Ampuero J, Cubero FJ, Chi-Cervera L, Ríos-Torres SL, Duarte-Rojo A, Espinosa-Cuevas Á, Romero-Gómez M, Torre A (2016).
Low phase angle is associated with the development of hepatic encephalopathy in patients with cirrhosis
WORLD JOURNAL OF GASTROENTEROLOGY. Article. 22(45):10064-10070.
[doi:10.3748/wjg.v22.i45.10064]
Teresa Martinez-Saavedra, Maria, Garcia-Gomez, Sonia, Dominguez Acosta, Ana, Mendoza Quintana, Juan Jesus, Poch Paez, Jesus, Garcia-Reino, Eduardo J., Camps, Gracian, Martinez-Barricarte, Ruben, Itan, Yuval, Boisson, Bertrand, Sanchez-Ramon, Silvia, Ramon Regueiro, Jose, Casanova, Jean-Laurent, Rodriguez-Gallego, Carlos, Perez de Diego, Rebeca (2016).
Gain-of-function mutation in PIK3R1 in a patient with a narrow clinical phenotype of respiratory infections
CLINICAL IMMUNOLOGY. Letter. 173:117-120.
[doi:10.1016/j.clim.2016.09.011]
Sheikh QM, Gatherer D, Reche PA, Flower DR (2016).
Towards the knowledge-based design of universal influenza epitope ensemble vaccines
Bioinformatics. Article. 32(21):3233-3239.
[doi:10.1093/bioinformatics/btw399]
Gutierrez Tenorio, Josue, Pinto Garcia, Sheila, Garcia-Fernandez, Jesus, Arjona, Emilia, Rodriguez de Cordoba, Santiago, Goicoechea de Jorge, Elena (2016).
Insight into the role of CFHR proteins in renal disease
Immunobiology. Meeting Abstract. 221(10, SI):1214-1214.
[doi:10.1016/j.imbio.2016.06.198]
Moreno A, Pineda F, Alcover J, Rodríguez D, Palacios R, Martínez-Naves E (2016).
Orthologous Allergens and Diagnostic Utility of Major Allergen Alt a 1
ALLERGY ASTHMA & IMMUNOLOGY RESEARCH. Article. 8(5):428-437.
[doi:10.4168/aair.2016.8.5.428]
Sirvent, S, Soria, I, Cirauqui, C, Cases, B, Manzano, AI, Diez-Rivero, CM, Reche, PA, Lopez-Relano, J, Martinez-Naves, E, Cañada FJ, Jimenez-Barbero, J, Subiza, J, Casanovas, M, Fernandez-Caldas, E, Subiza, JL, Palomares, O (2016).
Novel vaccines targeting dendritic cells by coupling allergoids to nonoxidized mannan enhance allergen uptake and induce functional regulatory T cells through programmed death ligand 1
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 138(2):558-558.
[doi:10.1016/j.jaci.2016.02.029]
Muñoz-Ruiz M, Ribot JC, Grosso AR, Gonçalves-Sousa N, Pamplona A, Pennington DJ, Regueiro JR, Fernández-Malavé E, Silva-Santos B (2016).
TCR signal strength controls thymic differentiation of discrete proinflammatory gamma delta T cell subsets
NATURE IMMUNOLOGY. Article. 17(6):721-721.
[doi:10.1038/ni.3424]
Recalde, Sergio, Tortajada, Agustin, Subias, Marta, Anter, Jaouad, Blasco, Miguel, Maranta, Ramona, Coco, Rosa, Pinto, Sheila, Noris, Marina, Garcia-Layana, Alfredo, Rodriguez de Cordoba, Santiago (2016).
Molecular Basis of Factor H R1210C Association with Ocular and Renal Diseases
JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY. Article. 27(5):1305-1311.
[doi:10.1681/ASN.2015050580]
Valés-Gómez M, Esteso G, Aydogmus C, Blázquez-Moreno A, Marín AV, Briones AC, Garcillán B, García-Cuesta EM, Cobo SL, Haskologlu S, Moraru M, Cipe F, Dobbs K, Dogu F, Parolini S, Notarangelo LD, Vilches C, Recio MJ, Regueiro JR, Ikinciogullari A, Reyburn HT (2016).
Natural killer cell hyporesponsiveness and impaired development in a CD247-deficient patient
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 137(3):942-945.
[doi:10.1016/j.jaci.2015.07.051]
Ramirez-Munoz R, Castro-Sánchez P, Roda-Navarro P (2016).
Ultrasensitivity in the Cofilin Signaling Module: A Mechanism for Tuning T Cell Responses
Frontiers in immunology. Article. 7:59-59.
[doi:10.3389/fimmu.2016.00059]
2015
Echbarthi, Meriem, Zonca, Manuela, Mellwig, Rachel, Schwab, Yannick, Kaplan, Gerardo, DeKruyff, Rosemarie H., Roda-Navarro, Pedro, Casasnovas, Jose M. (2015).
Distinct Trafficking of Cell Surface and Endosomal TIM-1 to the Immune Synapse
Traffic. Article. 16(11):1193-1207.
[doi:10.1111/tra.12329]
Reyes R, Monjas A, Yánez-Mó M, Cardeñes B, Morlino G, Gilsanz A, Machado-Pineda Y, Lafuente E, Monk P, Sánchez-Madrid F, Cabañas C (2015).
Different states of integrin LFA-1 aggregation are controlled through its association with tetraspanin CD9
BIOCHIMICA ET BIOPHYSICA ACTA-MOLECULAR CELL RESEARCH. Article. 1853(10):2464-2480.
[doi:10.1016/j.bbamcr.2015.05.018]
Jimenez-Reinoso, Anais, Marin, Ana V. M., Lopez-Lera, Alberto, Rodriguez de Cordoba, Santiago, Roman-Ortiz, Elena, Lopez-Trascasa, Margarita, Regueiro, Jose R. (2015).
Severe congenital plasma C3 deficiency does not preclude intracellular C3 expression by immortalized T cell lines in two unrelated patients
MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):147-148.
Jimenez-Reinoso, Anais, Lopez-Lera, Alberto, Marin, Ana V. M., Lopez-Relano, Juan, Martinez-Naves, Eduardo, Rodriguez de Cordoba, Santiago, Roman-Ortiz, Elena, Lopez-Trascasa, Margarita, Regueiro, Jose R. (2015).
Differential impairment of dendritic, Band T cell differentiation in congenital primary (C3-deficient) as opposed to secondary (factor I-deficient) human plasma C3 deficiencies
MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):147-147.
Marin, Ana V. M., Jimenez-Reinosol, Anais, Juana-Lopez, Lucia, Rodriguez de Cordoba, Santiago, Regueiro, Jose R. (2015).
Altered B cell and bone marrow-derived dendritic cell phenotype in mouse models with secondary C3 deficiency
MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):158-159.
Rahman, Sunniyat, Pinto, Sheila, Hajji, Nabil, Rodriguez de Cordoba, Santiago, Goicoechea de Jorge, Elena (2015).
miRNAs as novel biomarkers of disease status in atypical haemolytic uremic syndrome
MOLECULAR IMMUNOLOGY. Meeting Abstract. 67(1, SI):172-173.
Álvarez B, Escalona Z, Uenishi H, Toki D, Revilla C, Yuste M, Del Moral MG, Alonso F, Ezquerra A, Domínguez J (2015).
Molecular and functional characterization of porcine Siglec-3/CD33 and analysis of its expression in blood and tissues
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. Article. 51(2):238-250.
[doi:10.1016/j.dci.2015.04.002]
Jozsi, Mihaly, Tortajada, Agustin, Uzonyi, Barbara, Goicoechea de Jorge, Elena, Rodriguez de Cordoba, Santiago (2015).
Factor H-related proteins determine complement-activating surfaces
TRENDS IN IMMUNOLOGY. Review. 36(6):374-384.
[doi:10.1016/j.it.2015.04.008]
Csincsi ÁI, Kopp A, Zöldi M, Bánlaki Z, Uzonyi B, Hebecker M, Caesar JJ, Pickering MC, Daigo K, Hamakubo T, Lea SM, Goicoechea de Jorge E, Józsi M (2015).
Factor H-Related Protein 5 Interacts with Pentraxin 3 and the Extracellular Matrix and Modulates Complement Activation
JOURNAL OF IMMUNOLOGY. Article. 194(10):4963-4973.
[doi:10.4049/jimmunol.1403121]
Garcillán B, Marin AV, Jiménez-Reinoso A, Briones AC, Muñoz-Ruiz M, García-León MJ, Gil J, Allende LM, Martínez-Naves E, Toribio ML, Regueiro JR (2015).
gamma delta T lymphocytes in the diagnosis of human T cell receptor immunodeficiencies
Frontiers in immunology. Editorial Material. 6:20-20.
[doi:10.3389/fimmu.2015.00020]
López-Cotarelo P, Escribano-Díaz C, González-Bethencourt IL, Gómez-Moreira C, Deguiz ML, Torres-Bacete J, Gómez-Cabañas L, Fernández-Barrera J, Delgado-Martín C, Mellado M, Regueiro JR, Miranda-Carús ME, Rodríguez-Fernández JL (2015).
A Novel MEK-ERK-AMPK Signaling Axis Controls Chemokine Receptor CCR7-dependent Survival in Human Mature Dendritic Cells
JOURNAL OF BIOLOGICAL CHEMISTRY. Article. 290(2):827-840.
[doi:10.1074/jbc.M114.596551]
Molero-Abraham M, Glutting JP, Flower DR, Lafuente EM, Reche PA (2015).
EPIPOX: Immunoinformatic Characterization of the Shared T-Cell Epitome between Variola Virus and Related Pathogenic Orthopoxviruses
JOURNAL OF IMMUNOLOGY RESEARCH. Article. 2015:738020-738020.
[doi:10.1155/2015/738020]
Escalona Z, Álvarez B, Uenishi H, Toki D, Yuste M, Revilla C, del Moral MG, Alonso F, Ezquerra A, Domínguez J (2015).
Molecular characterization of porcine Siglec-10 and analysis of its expression in blood and tissues
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. Article. 48(1):116-123.
[doi:10.1016/j.dci.2014.09.011]
2014
Manuel Torres, Juan, Martinez-Barricarte, Ruben, Garcia-Gomez, Sonia, Mazariegos, Marina S., Itan, Yuval, Boisson, Bertrand, Alvarez, Rita, Jimenez-Reinoso, Anais, del Pino, Lucia, Rodriguez-Pena, Rebeca, Ferreira, Antonio, Hernandez-Jimenez, Enrique, Toledano, Victor, Cubillos-Zapata, Carolina, Diaz-Almiron, Mariana, Lopez-Collazo, Eduardo, Unzueta-Roch, Jose L., Sanchez-Ramon, Silvia, Regueiro, Jose R., Lopez-Granados, Eduardo, Casanova, Jean-Laurent, Perez de Diego, Rebeca (2014).
Inherited BCL10 deficiency impairs hematopoietic and nonhematopoietic immunity
JOURNAL OF CLINICAL INVESTIGATION. Article. 124(12):5239-5248.
[doi:10.1172/JCI77493]
Subias Hidalgo, Marta, Yebenes, Hugo, Dominguez, Mercedes, Jimenez, Anais, Regueiro, J. R., Llorca, Oscar, Rodriguez de Cordoba, Santiago (2014).
Dissection of C3 functions using novel mouse monoclonal antibodies to activated human C3 fragments
MOLECULAR IMMUNOLOGY. Meeting Abstract. 61(2, SI):253-254.
Roda-Navarro P, Bastiaens PI (2014).
Dynamic Recruitment of Protein Tyrosine Phosphatase PTPD1 to EGF Stimulation Sites Potentiates EGFR Activation
PLOS ONE. Article. 9(7).
[doi:10.1371/journal.pone.0103203]
Dopfer EP, Hartl FA, Oberg HH, Siegers GM, Yousefi OS, Kock S, Fiala GJ, Garcillán B, Sandstrom A, Alarcón B, Regueiro JR, Kabelitz D, Adams EJ, Minguet S, Wesch D, Fisch P, Schamel WW (2014).
The CD3 Conformational Change in the gamma delta T Cell Receptor Is Not Triggered by Antigens but Can Be Enforced to Enhance Tumor Killing
CELL REPORTS. Article. 7(5):1704-1715.
[doi:10.1016/j.celrep.2014.04.049]
Escalona Z, Álvarez B, Uenishi H, Toki D, Yuste M, Revilla C, Gómez del Moral M, Alonso F, Ezquerra A, Domínguez J (2014).
Molecular characterization and expression of porcine Siglec-5
DEVELOPMENTAL AND COMPARATIVE IMMUNOLOGY. Article. 44(1):206-216.
[doi:10.1016/j.dci.2013.12.013]
Garcillán B, Mazariegos MS, Fisch P, Res PC, Muñoz-Ruiz M, Gil J, López-Granados E, Fernández-Malavé E, Regueiro JR (2014).
Enrichment of the rare CD4(+) gamma delta T-cell subset in patients with atypical CD3 delta deficiency
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Letter. 133(4):1205-1208.
[doi:10.1016/j.jaci.2013.10.002]
2013
Adolph TE, Tomczak MF, Niederreiter L, Ko HJ, Böck J, Martinez-Naves E, Glickman JN, Tschurtschenthaler M, Hartwig J, Hosomi S, Flak MB, Cusick JL, Kohno K, Iwawaki T, Billmann-Born S, Raine T, Bharti R, Lucius R, Kweon MN, Marciniak SJ, Choi A, Hagen SJ, Schreiber S, Rosenstiel P, Kaser A, Blumberg RS (2013).
Paneth cells as a site of origin for intestinal inflammation
Nature. Article. 503(7475):272-272.
[doi:10.1038/nature12599]
Medraño-Fernandez I, Reyes R, Olazabal I, Rodriguez E, Sanchez-Madrid F, Boussiotis VA, Reche PA, Cabañas C, Lafuente EM (2013).
RIAM (Rap1-interacting adaptor molecule) regulates complement-dependent phagocytosis
CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 70(13):2395-2410.
[doi:10.1007/s00018-013-1268-6]
Iborra S, Ramos M, Arana DM, Lázaro S, Aguilar F, Santos E, López D, Fernández-Malavé E, Del Val M (2013).
N-ras couples antigen receptor signaling to Eomesodermin and to functional CD8(+) T cell memory but not to effector differentiation
JOURNAL OF EXPERIMENTAL MEDICINE. Article. 210(7):1463-1479.
[doi:10.1084/jem.20112495]
Abós-Gracia B, del Moral MG, López-Relaño J, Viana-Huete V, Castro L, Villalba M, Martínez-Naves E (2013).
Olea europaea pollen lipids activate invariant natural killer T cells by upregulating CD1d expression on dendritic cells
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 131(5):1393-221.
[doi:10.1016/j.jaci.2012.11.014]
Gilsanz A, Sánchez-Martín L, Gutiérrez-López MD, Ovalle S, Machado-Pineda Y, Reyes R, Swart GW, Figdor CG, Lafuente EM, Cabañas C (2013).
ALCAM/CD166 adhesive function is regulated by the tetraspanin CD9
CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 70(3):475-493.
[doi:10.1007/s00018-012-1132-0]
Roda-Navarro P (2013).
Microspectroscopy reveals mechanisms of lymphocyte activation
INTEGRATIVE BIOLOGY. Review. 5(2):300-311.
[doi:10.1039/c2ib20190a]
Munoz-Ruiz, Miguel, Perez-Flores, Veronica, Garcillan, Beatriz, Guardo, Alberto C., Mazariegos, Marina S., Takada, Hidetoshi, Allende, Luis M., Kilic, Sara S., Sanal, Ozden, Roifman, Chaim M., Lopez-Granados, Eduardo, Recio, Maria J., Martinez-Naves, Eduardo, Fernandez-Malave, Edgar, Regueiro, Jose R. (2013).
Human CD3 gamma, but not CD3 delta, haploinsufficiency differentially impairs gamma delta versus alpha beta surface TCR expression
BMC IMMUNOLOGY. Article. 14(3):3-3.
[doi:10.1186/1471-2172-14-3]
Munoz-Ruiz, M., Mazariegos, M. S., Garcillan, B., Sanz, M., Delgado, M., Fernandez-Malave, E., Regueiro, J. R. (2013).
Cd3 haploinsufficiencies reveal the existence of differential CD3 chain functions in murine alpha beta T cell development, phenotype and function.
Proceedings Of The 15th Meeting Of The European Society Immunodeficiencies (esid). Capítulo de un Libro. 105-110.
Molero-Abraham M, Lafuente EM, Flower DR, Reche PA (2013).
Selection of Conserved Epitopes from Hepatitis C Virus for Pan-Populational Stimulation of T-Cell Responses
CLINICAL & DEVELOPMENTAL IMMUNOLOGY. Article. 2013:601943-601943.
[doi:10.1155/2013/601943]
Jiménez-Periáñez A, Abos Gracia B, López Relaño J, Diez-Rivero CM, Reche PA, Martínez-Naves E, Matveyeva E, Gómez del Moral M (2013).
Mesoporous Silicon Microparticles Enhance MHC Class I Cross-Antigen Presentation by Human Dendritic Cells
CLINICAL & DEVELOPMENTAL IMMUNOLOGY. Article. 2013:362163-362163.
[doi:10.1155/2013/362163]
2012
García-Zaragoza E, Pérez-Tavarez R, Ballester A, Lafarga V, Jiménez-Reinoso A, Ramírez A, Murillas R, Gallego MI (2012).
Intraepithelial paracrine Hedgehog signaling induces the expansion of ciliated cells that express diverse progenitor cell markers in the basal epithelium of the mouse mammary gland
DEVELOPMENTAL BIOLOGY. Article. 372(1):28-44.
[doi:10.1016/j.ydbio.2012.09.005]
Coló GP, Lafuente EM, Teixidó J (2012).
The MRL proteins: Adapting cell adhesion, migration and growth
EUROPEAN JOURNAL OF CELL BIOLOGY. Review. 91(11-12):861-868.
[doi:10.1016/j.ejcb.2012.03.001]
Argilaguet, Jordi M., Perez-Martin, Eva, Nofrarias, Miquel, Gallardo, Carmina, Accensi, Francesc, Lacasta, Anna, Mora, Mercedes, Ballester, Maria, Galindo-Cardiel, Ivan, Lopez-Soria, Sergio, Escribano, Jose M., Reche, Pedro A., Rodriguez, Fernando (2012).
DNA Vaccination Partially Protects against African Swine Fever Virus Lethal Challenge in the Absence of Antibodies
PLOS ONE. Article. 7(9).
[doi:10.1371/journal.pone.0040942]
Munoz-Ruiz, M., Mazariegos, M. S., Garcillan, B., Delgado, M., Fernandez-Malave, E., Regueiro, J. R. (2012).
CD3 HAPLOINSUFFICIENCIES REVEAL THE EXISTENCE OF DIFFERENTIAL CD3 CHAIN FUNCTIONS IN MURINE.. T CELL DEVELOPMENT, PHENOTYPE AND FUNCTION EX AND IN VIVO
JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):19-20.
Garcillan, B., Mazariegos, M. S., Fish, P., Munoz-Ruiz, M., Gil, J., Lopez-Granados, E., Regueiro, J. R. (2012).
Study of gamma delta T cells in a Tab-Tgd plus B plus NK plus SCID due to CD3D mutations
Immunology. Meeting Abstract. 137(1, SI):569-569.
Mazariegos, M. S., Garcillan, B., Munoz-Ruiz, M., Regueiro, J. R. (2012).
Physiopathology of TCR/CD3: genomic induction in CD3gamma deficient cells
Immunology. Meeting Abstract. 137(1, SI):377-378.
Munoz-Ruiz, M., Mazariegos, M. S., Garcillan, B., Delgado, M., Fernandez-Malave, E., Regueiro, J. R. (2012).
Selective roles of CD3 chains in T cell development, TCR expression and T cell effector functions revealed by CD3 haploinsufficiencies
Immunology. Meeting Abstract. 137(1, SI):10-10.
Garcillan, B., Mazariegos, M. S., Fish, P., Munoz-Ruiz, M., Gil, J., Lopez-Granados, E., Recio, M. J., Regueiro, J. (2012).
CHARACTERIZATION OF Gamma Delta T LYMPHOCYTES IN TAB(-)T Gamma Delta plus B plus NK plus SCID DUE TO LEAKY CD3D MUTATIONS
JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):308-308.
Recio, M. J., Couso, J., Busto, E., Allende, L. M., van Montfrans, J., Lefranc, G., Pablos, J. L., Regueiro, J. R. (2012).
THE CD3G P.V131F MUTATION IN IMMUNODEFICIENCY AND AUTOIMMUNITY
JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):320-321.
Ruiz-Garcia, R., Recio, M. J., Dominguez-Pinilla, N., Mancebo, E., Martinez-Feito, A., Mora, S., Ramirez-Munoz, R., Menchen, M., Diaz-Madronero, M. J., Regueiro, J. R., Ruiz-Contreras, J., Paz-Artal, E., Allende-Martinez, L., Gonzalez-Granado, L. I. (2012).
NON-HOMOLOGOUS END-JOINING DEFECTS WITHIN DNA-REPAIRING DEFECTS: WIDE CLINICAL SPECTRUM AND OUTCOME IN A TERTIARY SINGLE HOSPITAL
JOURNAL OF CLINICAL IMMUNOLOGY. Meeting Abstract. 32(1):313-314.
Diez-Rivero, Carmen M., Reche, Pedro A. (2012).
CD8 T Cell Epitope Distribution in Viruses Reveals Patterns of Protein Biosynthesis
PLOS ONE. Article. 7(8).
[doi:10.1371/journal.pone.0043674]
Beltrán E, Hernández A, Lafuente EM, Coret F, Simó-Castelló M, Boscá I, Pérez-Miralles FC, Burgal M, Casanova B (2012).
Neuronal antigens recognized by cerebrospinal fluid IgM in multiple sclerosis
JOURNAL OF NEUROIMMUNOLOGY. Article. 247(1-2):63-69.
[doi:10.1016/j.jneuroim.2012.03.013]
Zakka, Labib R., Reche, Pedro A., Ahmed, A. Razzaque (2012).
The molecular basis for the presence of two autoimmune diseases occurring simultaneously - Preliminary observations based on computer analysis
AUTOIMMUNITY. Article. 45(3):253-263.
[doi:10.3109/08916934.2011.632454]
Muñoz Ruiz M, Regueiro JR (2012).
NEW TOOLS IN REGENERATIVE MEDICINE: Gene Therapy
Advances in Experimental Medicine and Biology. Article. 741:254-275.
[doi:10.1007/978-1-4614-2098-9_17]
2011
Martinez-Naves, Eduardo, Lafuente, Esther M., Reche, Pedro A. (2011).
Recognition of the ligand-type specificity of classical and non-classical MHC I proteins
FEBS LETTERS. Article. 585(21):3478-3484.
[doi:10.1016/j.febslet.2011.10.007]
Zakka, L. R., Reche, P., Ahmed, A. R. (2011).
Role of MHC Class II Genes in the pathogenesis of pemphigoid
AUTOIMMUNITY REVIEWS. Review. 11(1):40-47.
[doi:10.1016/j.autrev.2011.07.002]
Marcus, Nufar, Takada, Hidetoshi, Law, Jason, Cowan, Morton J., Gil, Juana, Regueiro, Jose R., Lopez de Sabando, Diego Plaza, Lopez-Granados, Eduardo, Dalal, Jignesh, Friedrich, Wilhelm, Manfred, Hoenig, Hanson, Imelda Celine, Grunebaum, Eyal, Shearer, William T., Roifman, Chaim M. (2011).
Hematopoietic stem cell transplantation for CD3 delta deficiency
JOURNAL OF ALLERGY AND CLINICAL IMMUNOLOGY. Article. 128(5):1050-1057.
[doi:10.1016/j.jaci.2011.05.031]
Dolores Gutierrez-Lopez, Maria, Gilsanz, Alvaro, Yanez-Mo, Maria, Ovalle, Susana, Lafuente, Esther M., Dominguez, Carmen, Monk, Peter N., Gonzalez-Alvaro, Isidoro, Sanchez-Madrid, Francisco, Cabanas, Carlos (2011).
The sheddase activity of ADAM17/TACE is regulated by the tetraspanin CD9
CELLULAR AND MOLECULAR LIFE SCIENCES. Article. 68(19):3275-3292.
[doi:10.1007/s00018-011-0639-0]
Gil, Juana, Busto, Elena M., Garcillan, Beatriz, Chean, Carmen, Cruz Garcia-Rodriguez, Maria, Diaz-Alderete, Andrea, Navarro, Joaquin, Reine, Jesus, Mencia, Angeles, Gurbindo, Dolores, Belendez, Cristina, Gordillo, Isabel, Duchniewicz, Marlena, Hoehne, Kerstin, Garcia-Sanchez, Felix, Fernandez-Cruz, Eduardo, Lopez-Granados, Eduardo, Schamel, Wolfgang W. A., Moreno-Pelayo, Miguel A., Recio, Maria J., Regueiro, Jose R. (2011).
A leaky mutation in CD3D differentially affects alpha beta and gamma delta T cells and leads to a T alpha beta T-gamma delta+B+NK+ human SCID
JOURNAL OF CLINICAL INVESTIGATION. Article. 121(10):3872-3876.
[doi:10.1172/JCI44254]
Abos, Beatriz, Gomez del Moral, Manuel, Gozalbo-Lopez, Beatriz, Lopez-Relano, Juan, Viana, Vanesa, Martinez-Naves, Eduardo (2011).
Human MR1 expression on the cell surface is acid sensitive, proteasome independent and increases after culturing at 26 degrees C
BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS. Article. 411(3):632-636.
[doi:10.1016/j.bbrc.2011.07.007]
Hernandez-Varas, Pablo, Colo, Georgina P., Bartolome, Ruben A., Paterson, Andrew, Medrano-Fernandez, Iria, Arellano-Sanchez, Nohem, Cabanas, Carlos, Sanchez-Mateos, Paloma, Lafuente, Esther M., Boussiotis, Vassiliki A., Stromblad, Staffan, Teixido, Joaquin (2011).
Rap1-GTP-interacting Adaptor Molecule (RIAM) Protein Controls Invasion and Growth of Melanoma Cells
JOURNAL OF BIOLOGICAL CHEMISTRY. Article. 286(21):18492-18504.
[doi:10.1074/jbc.M110.189811]
Iborra S, Soto M, Stark-Aroeira L, Castellano E, Alarcón B, Alonso C, Santos E, Fernández-Malavé E (2011).
H-ras and N-ras are dispensable for T-cell development and activation but critical for protective Th1 immunity
BLOOD. Article. 117(19):5102-5111.
[doi:10.1182/blood-2010-10-315770]
Fernández-Malavé E, Stark-Aroeira L (2011).
A natural anti-T-cell receptor monoclonal antibody protects against experimental autoimmune encephalomyelitis
JOURNAL OF NEUROIMMUNOLOGY. Article. 234(1-2):63-70.
[doi:10.1016/j.jneuroim.2011.02.006]
Marcus, N., Takada, H., Dalal, J., Regueiro, J. R., Friedrich, W., Roifman, C. (2011).
STEM CELL TRANSPLANTATION FOR CD3-DELTA DEFICIENCY
BIOLOGY OF BLOOD AND MARROW TRANSPLANTATION. Meeting Abstract. 17(2, 2):184-184.
[doi:10.1016/j.bbmt.2010.12.096]
Mancebo, Esther, Jose Recio, Maria, Martinez-Busto, Elena, Gonzalez-Granado, Luis I., Rojo, Pablo, Fernandez-Diaz, Eva, Ruiz-Contreras, Jesus, Paz-Artal, Estela, Allende, Luis M. (2011).
Possible role of Artemis c.512C > G polymorphic variant in Omenn syndrome
Dna Repair. Letter. 10(1):3-4.
[doi:10.1016/j.dnarep.2010.09.022]
Reine, Jesus, Busto, Elena M., Munoz-Ruiz, Miguel, Rossi, Nineth E., Rodriguez-Fernandez, Jose L., Martinez-Naves, Eduardo, Regueiro, Jose R., Recio, Maria J. (2011).
CD3 gamma-independent pathways in TCR-mediated signaling in mature T and iNKT lymphocytes
CELLULAR IMMUNOLOGY. Article. 271(1):62-66.
[doi:10.1016/j.cellimm.2011.06.009]
2010
Zakka, L. R., Keskin, D. B., Reche, P., Ahmed, A. R. (2010).
Relationship between target antigens and major histocompatibility complex (MHC) class II genes in producing two pathogenic antibodies simultaneously
CLINICAL AND EXPERIMENTAL IMMUNOLOGY. Review. 162(2):224-236.
[doi:10.1111/j.1365-2249.2010.04239.x]
Berger, Scott B., Romero, Xavier, Ma, Chunyan, Wang, Guoxing, Faubion, William A., Liao, Gongxian, Compeer, Ewoud, Keszei, Marton, Rameh, Lucia, Wang, Ninghai, Boes, Marianne, Regueiro, Jose R., Reinecker, Hans-Christian, Terhorst, Cox (2010).
SLAM is a microbial sensor that regulates bacterial phagosome functions in macrophages
NATURE IMMUNOLOGY. Article. 11(10):920-70.
[doi:10.1038/ni.1931]
Diez-Rivero, Carmen M., Lafuente, Esther M., Reche, Pedro A. (2010).
Computational analysis and modeling of cleavage by the immunoproteasome and the constitutive proteasome
BMC BIOINFORMATICS. Article. 11(479):479-479.
[doi:10.1186/1471-2105-11-479]
Liao, Gongxian, Nayak, Sushrusha, Regueiro, Jose R., Berger, Scott B., Detre, Cynthia, Romero, Xavier, Malefyt, Rene de Waal, Chatila, Talal A., Herzog, Roland W., Terhorst, Cox (2010).
GITR engagement preferentially enhances proliferation of functionally competent CD4(+)CD25(+)FoxP3(+) regulatory T cells
INTERNATIONAL IMMUNOLOGY. Article. 22(4):259-270.
[doi:10.1093/intimm/dxq001]
Martínez-Saavedra MT, García-Gomez S, Domínguez Acosta A, Mendoza Quintana JJ, Páez JP, García-Reino EJ, Camps G, Martinez-Barricarte R, Itan Y, Boisson B, Sánchez-Ramón S, Regueiro JR, Casanova JL, Rodríguez-Gallego C, Pérez de Diego R ().
Gain-of-function mutation in PIK3R1 in a patient with a narrow clinical phenotype of respiratory infections.
CLINICAL IMMUNOLOGY. Letter.