The MedChemLab has been involved in more than 21 projects funded in competitive calls by national and international sources and also in projects funded by pharmaceutical companies.
Currently active research projects
The MedChemLab has a consolidated experience in the transference of research results. The results generated by the group have been translated into 15 scientific projects funded by the private sector, into 14 international patents (PCT), 12 of them transferred and under exploitation by the pharma industry, and into the commercialization of compounds as pharmacological tools. This strong background has been recently recognized by the Universidad Complutense with the Technology and Knowledge Transference Award in the Biomedicine and Health Area (May 2017).
M.L. López-Rodríguez, B. Benhamú, H. Vázquez-Villa, J. Ballesteros et al.
1,2,4-Oxadiazole derivatives as modulators of the GLP1 receptor.
EP12005.365.7/2012
VIVIABIOTECH
M.L. López-Rodríguez, S. Ortega-Gutiérrez, M. Martín-Fontecha, M. Balabasquer, F.J. Ortega, N. Marín
New inhibitors of the enzyme isoprenylcysteine carboxyl methyltransferase (ICMT)
PCT/EP201330129
M.L. López-Rodríguez, B. Benhamú, H. Vázquez-Villa, J. García-Cárceles, F.A. Rodríguez de Fonseca, J.M. Brea Floriani, M.I. Loza
Novel biphenylsulfoximines as allosteric modulators of the dopamine D1 receptor
EP17382372
One of the MedChemLab objectives is the appropriate training of the next generation of scientists. More than 30 people have carried out their PhD projects in the MedChemLab and more than 17 postdoctoral researchers have joined the group from its inception. In addition, the members of the group have supervised more than 25 undergraduate scientific projects and 12 foreign researcher projects within Erasmus or other European Commission programs.
Identification of new inhibitors of the isoprenylcysteine carboxymethyltransferase (ICMT) enzyme
Moisés Balabasquer Peña
Universidad Complutense de Madrid, School of Chemistry
March 2013
Development of new antagonists of the 5-HT6 y 5-HT7 serotonin receptors
Rocío Almudena Medina Muñoz
Universidad Complutense de Madrid, School of Chemistry
July 2013
New inhibitors of the fatty acid synthase (FASN) enzyme: validation as a therapeutic target for the treatment of breast cancer
Carlos Turrado García
Universidad Complutense de Madrid, School of Chemistry
July 2013
Development of new ligands for the validation of the LPA1 lysophosphatidic acid receptor
Inés González Gil
Universidad Complutense de Madrid, School of Chemistry
October 2014
Development of chemical probes for the study of the 5-HT1A serotonin receptor
Ana María Gamo Albero
Universidad Complutense de Madrid, School of Chemistry
November 2014
Chemical probes for the study of the endogenous cannabinoid system
Ainoa Rueda Zubiaurre
Universidad Complutense de Madrid, School of Chemistry
October 2015
Blockade of tumoral processes by inhibition of angiogenesis and Ras protein activity
Nagore I. Marín Ramos
Universidad Complutense de Madrid, School of Chemistry
December 2015
Validation of the ICMT enzyme as a new therapeutic target for the treatment of cancer and progeria
Francisco J. Ortega Nogales
Universidad Complutense de Madrid, School of Chemistry
July 2016
Allosteric modulators of serotonin and dopamine receptors: new drugs on GPCRs
Javier García Cárceles
Universidad Complutense de Madrid, School of Chemistry
April 2017
LPA1 and LPA2 receptors as new therapeutic targets for the treatment of central nervous system pathologies
Debora Zian
Universidad Complutense de Madrid, School of Chemistry
May 2017
